公开(公告)号：US20230244058A1

公开(公告)日：2023-08-03

申请号：US18112061

申请日：2023-02-21

Applicant: Eric Todd Marple ,  Kirk David Urmey

Inventor： Eric Todd Marple ,  Kirk David Urmey

IPC: G02B7/10 ,  G02B5/32 ,  G02B5/18 ,  G03H1/02 ,  G02B7/02 ,  G01J3/02 ,  G01J3/18 ,  G02B27/30

CPC classification number: G02B7/10 ,  G02B5/32 ,  G02B5/1866 ,  G03H1/0248 ,  G02B7/021 ,  G01J3/0208 ,  G01J3/1838 ,  G02B27/30 ,  G01J3/44

Abstract: The technology provides a spectroscopy system having a fringe tilted grating that varies a refractive index to diffract light. The diffracting mechanism may be formed by modulating a refractive index to produce fringe planes that are oriented relative to each other through a depth of the grating material The spectroscopy system includes a detector that converts optical signals into electrical signals to render spectral data. The spectroscopy system employs the fringe tilted grating to minimize fictitious Raman peaks that correspond to a fluorescence response signature.

公开(公告)号：US20190186991A1

公开(公告)日：2019-06-20

申请号：US15844228

申请日：2017-12-15

Applicant: Horiba Instruments Incorporated

Inventor： Ronald Joseph KOVACH ,  Salvatore Hauptmann ATZENI

IPC: G01J3/02 ,  G01J3/18 ,  G01J3/42

CPC classification number: G01J3/0256 ,  G01J3/0202 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0235 ,  G01J3/0237 ,  G01J3/0291 ,  G01J3/04 ,  G01J3/18 ,  G01J3/1838 ,  G01J3/40 ,  G01J3/42 ,  G01J2003/045 ,  G01J2003/1842

Abstract: An optical instrument for spectroscopy applications includes a compact arrangement having a three-dimensional folded optical path. A plate configured as an optical reference plane is secured to a housing and is configured to secure optical components above or below the plate. A modular light source module may be secured within the housing without fasteners. A monochromator and spectrometer are secured below the plate. Mirrors disposed above the plate are configured to direct light from the monochromator passing through a first opening in the plate through a sample disposed above the plate, and to direct light from the sample through a second opening in the plate to the spectrometer. A controller is configured for communication with the monochromator and the spectrometer. The controller may control an entrance slit actuator for the spectrometer and positioning of an aperture upstream of the spectrometer to adjust resolution and throughput.

公开(公告)号：US20190183346A1

公开(公告)日：2019-06-20

申请号：US16284514

申请日：2019-02-25

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G16H40/67 ,  G01N33/15 ,  G01J3/10 ,  G01J3/28 ,  G01J3/42 ,  G01J3/453 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01J3/02 ,  A61C19/04 ,  G01J3/14 ,  G01N33/49 ,  G01N33/44

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7203 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  A61C1/0046 ,  A61C19/04 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A smart phone or tablet includes laser diodes, at least some of which may be pulsed and generate near-infrared light and include Bragg reflectors to direct light to tissue/skin. An array of laser diodes generates near-infrared light and has an assembly in front of the array that forms the light into a plurality of spots on the tissue/skin. A receiver includes detectors that receive light reflected from the tissue/skin. An infrared camera receives light reflected from the tissue/skin and generates data based on the received light. The smart phone or tablet is configured to generate a two-dimensional or three-dimensional image using at least part of the data from the infrared camera.

公开(公告)号：US09995722B2

公开(公告)日：2018-06-12

申请号：US15855201

申请日：2017-12-27

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  G01N33/15 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/145 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  G01N21/3563 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/44 ,  G01N33/49 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18 ,  G01M3/38

CPC classification number: G01N33/15 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/0088 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3513 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  H01S3/302

Abstract: A measurement system includes a light source having semiconductor sources configured to generate an input optical beam, a multiplexer configured form an intermediate optical beam from the input optical beam, fibers including a fused silica fiber configured to receive the intermediate optical beam and to form an output optical beam. The output optical beam comprises wavelengths between 700 and 2500 nanometers with a bandwidth of at least 10 nanometers. A measurement apparatus is configured to deliver the output beam to a sample to generate a spectroscopy output beam. A receiver is configured to receive and process the spectroscopy output beam to generate an output signal, wherein the receiver processing includes chemometrics or multivariate analysis methods to permit identification of materials within the sample, the light source and the receiver are remote from the sample, and the sample includes plastics or food industry goods.

公开(公告)号：US20180140198A1

公开(公告)日：2018-05-24

申请号：US15860065

申请日：2018-01-02

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/453 ,  A61B5/145 ,  A61B5/1455 ,  G01J3/10 ,  G01J3/28 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N33/49 ,  G01N33/44 ,  G01N33/15 ,  G01N33/02 ,  G01N21/88 ,  G01M3/38 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device includes a measurement device having light emitting diodes (LEDs) measuring a physiological parameter. The measurement device modulates the LEDs to generate an optical beam having a near-infrared wavelength between 700-2500 nanometers. Lenses receive and deliver the optical beam to tissue, which reflects the optical beam to a receiver having spatially separated detectors coupled to analog-to-digital converters configured to generate receiver outputs. The receiver captures light while the LEDs are off, and reflected light from the tissue while the LEDs are on, to generate first and second signals, respectively. Signal-to-noise ratio is improved by differencing the first and second signals and by differencing the receiver outputs. The measurement device further improves signal-to-noise ratio of the reflected optical beam by increasing light intensity of the LEDs relative to an initial light intensity. The measurement device generates an output signal representing a non-invasive measurement on blood contained within the tissue.

公开(公告)号：US09885698B2

公开(公告)日：2018-02-06

申请号：US15212549

申请日：2016-07-18

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  G01N33/15 ,  A61B5/1455 ,  A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  G01J3/14 ,  A61B5/145 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  G01J3/42 ,  G01J3/02 ,  H01S3/30 ,  G01J3/18 ,  G01M3/38 ,  G01J3/12 ,  G01N21/35 ,  G01N21/85 ,  G01N21/95 ,  H01S3/067 ,  H01S3/00

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device for use with a smart phone or tablet includes a measurement device having a light source with a plurality of light emitting diodes (LEDs) for measuring physiological parameters and configured to generate an optical beam with wavelengths including a near-infrared wavelength between 700 and 2500 nanometers. The measurement device includes lenses configured to deliver the optical beam to a sample of skin or tissue, which reflects the optical beam to a receiver located a first distance from one of the LEDs and a different distance from another of the LEDs, and is also configured to generate an output signal representing a non-invasive measurement on blood contained within the sample. The wearable device is configured to communicate with the smart phone or tablet, which receives, processes, stores and displays the output signal with the processed output signal configured to be transmitted over a wireless transmission link.

公开(公告)号：US20170071474A1

公开(公告)日：2017-03-16

申请号：US15357136

申请日：2016-11-21

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01N21/88 ,  G01N21/39 ,  G01N21/3563

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device for use with a smart phone or tablet includes a measurement device having a plurality of LEDs generating a near-infrared input optical beam that measures physiological parameters. The measurement device includes lenses configured to receive and to deliver the input beam to skin which reflects the beam. The measurement device includes a reflective surface configured to receive and redirect the light from the skin, and a receiver configured to receive the reflected beam. The light source is configured to increase a signal-to-noise ratio of the input beam reflected from the skin by increasing the light intensity from the LEDs and modulation of the LEDs. The measurement device is configured to generate an output signal representing a non-invasive measurement on blood contained within the skin. The wearable device is configured to wirelessly communicate with the smart phone or tablet which receives and processes the output signal.

Abstract translation: 用于智能手机或平板电脑的可佩戴装置包括具有多个LED的测量装置，所述多个LED产生测量生理参数的近红外输入光束。 测量装置包括被配置为接收并将输入光束传送到反射光束的皮肤的透镜。 测量装置包括被配置为接收并重定向来自皮肤的光的反射表面和被配置为接收反射光束的接收器。 光源被配置为通过增加来自LED的光强度和LED的调制来增加从皮肤反射的输入光束的信噪比。 测量装置被配置为产生表示对包含在皮肤内的血液进行非侵入性测量的输出信号。 可穿戴设备被配置为与接收和处理输出信号的智能电话或平板电脑进行无线通信。

公开(公告)号：US20170067820A1

公开(公告)日：2017-03-09

申请号：US15357225

申请日：2016-11-21

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: G01N21/3563 ,  G01J3/28 ,  G01N21/39 ,  G01N33/44 ,  G01N33/02

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A measurement system includes semiconductor light sources generating an input beam, optical amplifiers receiving the input beam and delivering an intermediate beam, and fused silica fibers with core diameters less than 400 microns receiving and delivering the intermediate beam to the fibers forming a first optical beam. A nonlinear element receives the first optical beam and broadens the spectrum to at least 10 nm through a nonlinear effect to form the output optical beam which includes a near-infrared wavelength of 700-2500 nm. A measurement apparatus is configured to receive the output optical beam and deliver it to a sample to generate a spectroscopy output beam. A receiver receives the spectroscopy output beam having a bandwidth of at least 10 nm and processes the beam to generate an output signal, wherein the light source and the receiver are remote from the sample, and wherein the sample comprises plastics or food industry goods.

Abstract translation: 测量系统包括产生输入光束的半导体光源，接收输入光束的光放大器和输送中间光束，以及芯直径小于400微米的熔融石英光纤接收并将中间光束传送到形成第一光束的光纤。 非线性元件接收第一光束并且通过非线性效应将光谱扩展至至少10nm，以形成包括700-2500nm的近红外波长的输出光束。 测量装置被配置为接收输出光束并将其传送到样本以产生光谱输出光束。 接收器接收具有至少10nm的带宽的光谱输出光束，并处理该光束以产生输出信号，其中光源和接收器远离样品，并且其中样品包括塑料或食品工业产品。

公开(公告)号：US20160047787A1

公开(公告)日：2016-02-18

申请号：US14875709

申请日：2015-10-06

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01N33/15 ,  G01N33/49 ,  G01N21/359

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A measurement system includes a light source generating an output optical beam using semiconductor sources generating an input beam, optical amplifiers outputting an intermediate beam, and optical fibers receiving the intermediate beam and forming a first optical beam. A nonlinear element broadens the output beam spectrum to at least 10 nm, the spectrum comprising a near-infrared wavelength of 700-2500 nm. A measurement apparatus receives the output optical beam and delivers to a sample an analysis output beam. A receiver receives and processes the analysis output beam reflected or transmitted from the sample.

Abstract translation: 测量系统包括使用产生输入光束的半导体源产生输出光束的光源，输出中间光束的光放大器和接收中间光束并形成第一光束的光纤。 非线性元件将输出光束光谱拓宽至至少10nm，该光谱包括700-2500nm的近红外波长。 测量装置接收输出光束并向样品传送分析输出光束。 接收器接收并处理从样本反射或发射的分析输出光束。

公开(公告)号：US08885162B2

公开(公告)日：2014-11-11

申请号：US13669634

申请日：2012-11-06

Applicant: Olympus Corporation

Inventor： Masaharu Tomioka

IPC: G01J3/28 ,  G01J3/18 ,  G02B21/00 ,  G01J3/06 ,  G01J3/02 ,  G01J3/44

CPC classification number: G02B21/0076 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0237 ,  G01J3/06 ,  G01J3/1838 ,  G01J3/4406 ,  G02B21/0064

Abstract: Provided is a detection optical system that is provided with a dispersed-light detection function and that can increase the amount of detected light by enhancing the diffraction efficiency. A detection optical system is employed which includes a transmissive VPH diffraction grating that disperses fluorescence from a specimen into a plurality of wavelength bands; a rotating mechanism that rotates the VPH diffraction grating about an axial line that is perpendicular to an incident optical axis of the fluorescence from the specimen and an emission optical axis from the VPH diffraction grating; a light detection portion that detects the fluorescence from the specimen that has been dispersed by the VPH diffraction grating; and a correcting portion that corrects an incident position on the light detection portion in accordance with a displacement of the optical axis caused by the rotation of the VPH diffraction grating in synchronization with the rotating mechanism.

Abstract translation: 提供了一种具有分散光检测功能并且可以通过提高衍射效率来增加检测光量的检测光学系统。 使用检测光学系统，其包括将来自样本的荧光分散到多个波长带中的透射VPH衍射光栅; 围绕垂直于来自样本的荧光的入射光轴的轴线和来自VPH衍射光栅的发射光轴旋转VPH衍射光栅的旋转机构; 光检测部，其检测由所述VPH衍射光栅分散的所述样本的荧光; 以及校正部，其根据与旋转机构同步的VPH衍射光栅的旋转引起的光轴的位移校正光检测部上的入射位置。