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    Smartphone-Based Apparatus and Method
    1.
    发明申请
    Smartphone-Based Apparatus and Method 有权
    基于智能手机的设备和方法

    公开(公告)号：US20160080548A1

    公开(公告)日：2016-03-17

    申请号：US14804386

    申请日：2015-07-21

    Applicant: Cornell University

    Inventor： David Erickson ,  Seoho Lee ,  Dakota O'Dell ,  Saurabh Mehta ,  Vlad-Victor Oncescu ,  Matthew Mancuso

    IPC: H04M1/725 ,  H04N5/225 ,  G01N21/80 ,  G01N33/487 ,  G01N21/78 ,  G06K9/46 ,  G06T7/40

    CPC classification number: H04M1/72527 ,  G01N21/78 ,  G01N21/80 ,  G01N21/8483 ,  G01N33/48785 ,  G01N2021/7759 ,  G01N2201/0221 ,  G01N2201/062 ,  G01N2201/127 ,  H04N5/2251

    Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.

    Abstract translation: 使用智能手机获得测试条上的分析物的收集点的选定定量标记的方法涉及对由于智能手机的测试条照明而在其上发生目标样品的比色反应的测试条进行成像。 智能手机包括智能手机应用程序和智能手机附件，可提供独立于所使用智能手机平台的外部环境独立/内部无光环境的成像环境。 然后可以将结果定量呈现或变成更为消费者友好的测量（正，负，高于平均水平等），显示给用户，存储供以后使用，并传达到从业者可以提供额外审查的位置。 此外，社交媒体整合可以允许将设备结果广播给特定的受众，将健康生活与他人进行比较，以竞争健康的游戏，创建映射和其他应用程序。

    Device and method for point-of-care diagnostics and antibiotic resistance identification, and applications thereof
    5.
    发明授权
    Device and method for point-of-care diagnostics and antibiotic resistance identification, and applications thereof 有权

    公开(公告)号：US10345295B2

    公开(公告)日：2019-07-09

    申请号：US15875686

    申请日：2018-01-19

    Applicant: CORNELL UNIVERSITY

    Inventor： Saurabh Mehta ,  David Erickson ,  Seoho Lee

    IPC: G01N33/543 ,  G01N33/558 ,  B01L3/00 ,  C12Q1/18

    Abstract: A device for detecting the presence of a target in a sample including a first port configured to receive a multi-layered substrate having a sample inlet and a reagent inlet. The sample inlet is connected to a first microfluidic channel and the reagent inlet is connected to both the first microfluidic channel and a second microfluidic channel. The second microfluidic channel has a longer pathway than the first microfluidic channel. A first test strip and a second test strip are each connected to both the first microfluidic channel and the second microfluidic channel, while a third test strip is connected only to the first microfluidic channel. Each test strip includes a conjugate section, a detection section, and a collection section.

    SMARTPHONE-BASED APPARATUS AND METHOD FOR OBTAINING REPEATABLE, QUANTITATIVE COLORIMETRIC MEASUREMENT
    7.
    发明申请
    SMARTPHONE-BASED APPARATUS AND METHOD FOR OBTAINING REPEATABLE, QUANTITATIVE COLORIMETRIC MEASUREMENT 有权
    基于智能手段的设备和获取可重复定量色彩测量的方法

    公开(公告)号：US20150359458A1

    公开(公告)日：2015-12-17

    申请号：US14762214

    申请日：2014-01-21

    Applicant: CORNELL UNIVERSITY

    Inventor： David Erickson ,  Dakota O'Dell ,  Vlad-Victor Oncescu ,  Matthew Mancuso ,  Seoho Lee

    IPC: A61B5/103 ,  G06T7/40 ,  G01N21/78

    CPC classification number: A61B5/1032 ,  A61B5/0022 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/157 ,  A61B5/4845 ,  A61B5/6898 ,  G01N21/78 ,  G01N21/80 ,  G01N33/52 ,  G01N33/558 ,  G06F19/00 ,  G06T7/90 ,  G06T2207/10024 ,  G06T2207/10056 ,  G06T2207/30024 ,  G16H40/67

    Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.

    Abstract translation: 使用智能手机获得测试条上的分析物的收集点的选定定量标记的方法涉及对由于智能手机的测试条照明而在其上发生目标样品的比色反应的测试条进行成像。 智能手机包括智能手机应用程序和智能手机附件，可提供独立于所使用智能手机平台的外部环境独立/内部无光环境的成像环境。 然后可以将结果定量呈现或变成更为消费者友好的测量（正，负，高于平均水平等），显示给用户，存储供以后使用，并传达到从业者可以提供额外审查的位置。 此外，社交媒体整合可以允许将设备结果广播给特定的受众，将健康生活与他人进行比较，以竞争健康的游戏，创建映射和其他应用程序。

    APPARATUS AND METHOD FOR POINT-OF-COLLECTION MEASUREMENT OF A BIOMOLECULAR REACTION
    8.
    发明申请
    APPARATUS AND METHOD FOR POINT-OF-COLLECTION MEASUREMENT OF A BIOMOLECULAR REACTION 有权
    生物分子反应点收集测量的装置和方法

    公开(公告)号：US20150244852A1

    公开(公告)日：2015-08-27

    申请号：US14427049

    申请日：2013-09-06

    Applicant: CORNELL UNIVERSITY

    Inventor： David Erickson ,  Matthew Mancuso ,  Seoho Lee

    IPC: H04M1/725 ,  G01N21/78 ,  G01N21/31

    CPC classification number: H04M1/72527 ,  B01L3/502715 ,  G01N21/31 ,  G01N21/78 ,  G01N33/48792 ,  G01N2015/0038 ,  G01N2035/00881 ,  G01N2201/062 ,  G01N2201/12 ,  G06F19/00 ,  G06F19/3418 ,  G06Q50/22 ,  G16H10/40 ,  G16H40/63 ,  Y02A90/22 ,  Y02A90/26

    Abstract: A system, methods, and apparatus for biomolecular measurements, monitoring, and tracking uses a smartphone-based system. A biological sample, including, but not limited to blood, saliva, biopsy, or sweat, is collected on a modular diagnostic test platform, which is then inserted into a smartphone accessory. Optical, electrical, mechanical, or other means are used to transduce a biomolecular binding event, including antibody, aptamer, enzymatic, base-pair matching, or other biological recognition reaction and communicate the results with the smartphone. Some specific examples of targets include 25-hydroxyvitamin D, folic acid, DNA, or proteins from infectious agents, and zinc. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later comparison, and communicated to a central hub location where medical professionals can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with friends, to compete in health based games, create mappings, and other applications.

    Abstract translation: 用于生物分子测量，监测和跟踪的系统，方法和装置使用基于智能手机的系统。 将生物样品（包括但不限于血液，唾液，活组织检查或汗液）收集在模块化诊断测试平台上，然后将其插入智能手机附件。 光学，电学，机械或其他手段用于转导生物分子结合事件，包括抗体，适体，酶，碱基对匹配或其他生物识别反应，并将结果与​​智能手机通信。 目标的一些具体实例包括25-羟基维生素D，叶酸，DNA或来自感染剂的蛋白质和锌。 然后可以将结果定量呈现或变成对消费者友好的测量（正，负，高于平均水平等），显示给用户，存储供以后比较，并传达给医疗专业人员可以提供的中心枢纽位置 额外的评论。 此外，社交媒体整合可以允许将设备结果广播到特定的观众，将健康生活与朋友进行比较，竞争健康游戏，创建映射和其他应用程序。

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