公开(公告)号：US20150216417A1

公开(公告)日：2015-08-06

申请号：US14421979

申请日：2013-08-16

Applicant: NATIONAL UNIVERSITY OF SINGAPORE

Inventor： Zhiwei Huang ,  Mads Sylvest Bergholt ,  Wei Zheng ,  Khek Yu Ho

IPC: A61B5/00

CPC classification number: A61B5/0075 ,  A61B5/0086 ,  A61B5/4233 ,  A61B5/4238 ,  A61B5/441 ,  A61B5/7221 ,  A61B5/7282 ,  A61B2562/0233 ,  G01J3/0221 ,  G01J3/0289 ,  G01J3/44 ,  G01N21/65

Abstract: A probe head for a diagnostic instrument, the probe head comprising; a transmission optical fiber, a plurality of collection optical fibers, and a lens to transmit light from the transmission optical fiber to a test site, wherein the ends of the collection optical fibers are bevelled.

Abstract translation: 一种用于诊断仪器的探头，所述探头包括： 传输光纤，多个收集光纤和透镜，用于将光从传输光纤传输到测试位置，其中收集光纤的端部被斜切。

公开(公告)号：US20150230697A1

公开(公告)日：2015-08-20

申请号：US14429132

申请日：2013-09-19

Applicant: Nanyang Technological University ,  National University of Singapore

Inventor： Soo Jay Louis Phee ,  Van An Huynh ,  Zheng Wang ,  Isaac David Penny ,  Khek Yu Ho

IPC: A61B1/012 ,  A61B1/005 ,  A61B1/05 ,  A61B1/018

CPC classification number: A61B1/0125 ,  A61B1/00098 ,  A61B1/00135 ,  A61B1/00183 ,  A61B1/0051 ,  A61B1/0057 ,  A61B1/018 ,  A61B1/05 ,  A61B8/12 ,  A61B8/4466 ,  A61B34/30 ,  A61B34/37 ,  A61B34/71 ,  A61B2017/2906 ,  A61B2034/303 ,  F04C2270/0421 ,  Y10S901/02 ,  Y10S901/41

Abstract: A master-slave robotic endoscopy system includes a flexible primary endoscope probe having at least one tool channel for carrying a tendon-sheath driven robot arm and corresponding end effector, and a secondary endoscope probe channel for carrying an imaging endoscope. The imaging endoscope provides enhanced image capture range relative to a distal end of the primary endoscope probe by way of a secondary endoscope probe channel distal opening proximally offset from the primary endoscope probe distal end; a ramp structure distally carried by the primary endoscope probe; and/or one or more actuatable distal imaging endoscope regions. Robot arms can include joint primitives that enable robot arm/end effector manipulation in accordance with intended degrees of freedom. A set of quick connect/disconnect interfaces couple an actuation controller to one or more actuation assemblies insertable into the tool channel(s), where each actuation assembly includes tendon-sheath elements, a robot arm, and its corresponding end effector.

Abstract translation: 主从机器人内窥镜系统包括具有至少一个用于承载腱鞘驱动的机器人手臂和相应的末端执行器的工具通道的柔性主内窥镜探针和用于承载成像内窥镜的辅助内窥镜探针通道。 成像内窥镜通过从主内窥镜探针远端向近侧偏移的第二内窥镜探针通道远侧开口提供相对于主内窥镜探针的远端的增强的图像捕获范围; 由主内窥镜探针远端承载的斜坡结构; 和/或一个或多个可致动的远端成像内窥镜区域。 机器人手臂可以包括根据预期的自由度使机器人手臂/末端执行器操纵的关节基元。 一组快速连接/断开接口将致动控制器耦合到可插入到工具通道中的一个或多个致动组件，其中每个致动组件包括腱鞘元件，机器人臂及其对应的端部执行器。

公开(公告)号：US09931039B2

公开(公告)日：2018-04-03

申请号：US14412053

申请日：2013-07-02

Applicant: National University of Singapore

Inventor： Zhiwei Huang ,  Khek Yu Ho ,  Mads Sylvest Bergholt ,  Wei Zheng ,  Khay Guan Yeoh ,  Shiyamala Duraipandian

IPC: A61B5/02 ,  A61B5/00 ,  A61B1/00 ,  G01N21/65 ,  G01N21/27 ,  G01J3/44

CPC classification number: A61B5/0075 ,  A61B1/00165 ,  A61B5/0084 ,  A61B2560/0233 ,  G01J2003/4424 ,  G01N21/274 ,  G01N21/65 ,  G01N2021/656 ,  G01N2201/08 ,  G01N2201/12753 ,  G01N2201/129

Abstract: A method of achieving instrument independent measurements for quantitative analysis of fiber-optic Raman spectroscope system, the system comprising a laser source, a spectroscope and a fiber optic probe to transmit light from the laser source to a target and return scattered light to the spectroscope, the method comprising transmitting light from the laser source to a standard target having a known spectrum, recording a calibration spectrum of the scattered light from the standard target, comparing the known spectrum and the calibration system and generating a probe and/or probe-system transfer function, and storing the transfer function. Further provided is a method of performing real-time diagnostic Raman spectroscopy optionally in combination with the other disclosed methods.

公开(公告)号：US09877655B2

公开(公告)日：2018-01-30

申请号：US14768521

申请日：2014-02-19

Applicant: National University of Singapore

Inventor： Zhiwei Huang ,  Mads Sylvest Bergholt ,  Wei Zheng ,  Khek Yu Ho

IPC: A61B5/00 ,  G01J3/28 ,  G01J3/44 ,  G01N21/65 ,  G02B23/24 ,  G02B23/26 ,  G01J3/02 ,  A61B1/00 ,  G01J3/18

CPC classification number: A61B5/0075 ,  A61B1/00165 ,  A61B5/0084 ,  G01J3/0218 ,  G01J3/0272 ,  G01J3/18 ,  G01J3/28 ,  G01J3/44 ,  G01N21/65 ,  G01N2201/129 ,  G02B23/2469 ,  G02B23/26

Abstract: A diagnostic instrument comprises a monochromatic light source, transmission means to transmit light from the light source to a test site, collection means to transmit scattered light from the test site, and spectral analysis apparatus to receive light from the collection means, the spectral analysis apparatus comprising a diffraction grating having a first grating element and a second grating element, wherein the first grating element diffracts light within a first wavelength range and the second grating element diffracts light within a second wavelength range, the spectral analysis apparatus further comprising a light-sensing apparatus, the first grating element arranged to diffract light onto a first area of the light-sensing apparatus and the second grating element arranged to diffract light onto a second area of the light-sensing apparatus.

公开(公告)号：US09622825B2

公开(公告)日：2017-04-18

申请号：US14121594

申请日：2014-09-22

Applicant: NATIONAL UNIVERSITY OF SINGAPORE ,  NANYANG TECHNOLOGICAL UNIVERSITY

Inventor： Soo Jay Louis Phee ,  Soon Chiang Low ,  Khek Yu Ho ,  Sheung Chee Chung

IPC: A61B1/00 ,  A61B34/30 ,  B25J9/16 ,  A61B1/04

CPC classification number: A61B34/30 ,  A61B1/00087 ,  A61B1/0014 ,  A61B34/74 ,  A61B34/76 ,  A61B2034/301 ,  B25J9/1674 ,  B25J9/1689 ,  G05B2219/45118

Abstract: A robotic manipulator 100, controller 300 and system for use in flexible endoscopy, the manipulator 100 comprising a flexible member configured to be coupled to an endoscope, and an arm connected to and movable by the flexible member, wherein the flexible member has a first end connected to the arm and a second end connectable to the controller 300 to allow a physical movement of the arm to be controllable by a physical movement of the controller 300.

公开(公告)号：US10470909B2

公开(公告)日：2019-11-12

申请号：US15749437

申请日：2016-08-19

Applicant: NANYANG TECHNOLOGICAL UNIVERSITY ,  NATIONAL UNIVERSITY OF SINGAPORE

Inventor： Soo Jay Louis Phee ,  Thanh Nho Do ,  Tian En Timothy Seah ,  Khek Yu Ho

IPC: A61F5/00 ,  A61B34/00 ,  A61L31/14

Abstract: An intragastric device comprising: an inflation magnet provided within a capsule and configured to move towards a first end of a capsule during activation of the intragastric device by applying a magnetic field externally to a user after swallowing the intragastric device; a first chamber and a second chamber physically separated by a partition having a through hole; a separator connected to the inflation magnet and sealing the through hole before activation of the intragastric device, wherein activation of the intragastric device moves the separator to unseal the through hole to allow a chemical reaction between a first chemical stored in the first chamber and a second chemical stored in the second chamber; a balloon secured to the capsule and collapsed against the capsule before activation of the intragastric device; and an expandable volume configured to expand when the balloon is inflated by a gaseous product of the chemical reaction.