公开(公告)号：DE3302442A1

公开(公告)日：1984-07-26

申请号：DE3302442

申请日：1983-01-26

Applicant: BASF AG

Inventor： THYES MARCO DR ,  ROSSY PHILLIP A DR ,  KOENIG HORST PROF DR ,  LEHMANN HANS DIETER PROF DR ,  GRIES JOSEF DR MED ,  LENKE DIETER PROF DR

IPC: A61K31/50 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/14

公开(公告)号：DE3302021A1

公开(公告)日：1984-07-26

申请号：DE3302021

申请日：1983-01-22

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST PROF DR ,  LEHMANN HANS DIETER PROF DR ,  GRIES JOSEF DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER PROF DR

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

公开(公告)号：AT53210T

公开(公告)日：1990-06-15

申请号：AT87100041

申请日：1987-01-03

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  SCHMIED BERNHARD DR ,  KROPP RUDOLF ,  BALDINGER VERENA DR ,  GRIES JOSEF DR ,  LEHMANN HANS DIETER PROF DR ,  RUEBSAMEN KLAUS DR ,  TRAUT MARTIN DR

IPC: C07D237/00 ,  A61K31/50 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D403/04 ,  C07D403/10

公开(公告)号：DE3471655D1

公开(公告)日：1988-07-07

申请号：DE3471655

申请日：1984-01-16

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST PROF DR ,  LEHMANN HANS DIETER PROF DR ,  GRIES JOSEF DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER PROF DR

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

公开(公告)号：DE3819052A1

公开(公告)日：1989-12-07

申请号：DE3819052

申请日：1988-06-04

Applicant: BASF AG

Inventor： SCHMIED BERNHARD DR ,  LEHMANN HANS DIETER PROF DR ,  BALDINGER VERENA DR ,  RUEBSAMEN KLAUS DR

IPC: A61K31/18 ,  A61K31/185 ,  A61K31/19 ,  A61K31/22 ,  A61K31/41 ,  A61K31/66 ,  A61K31/675 ,  A61P7/02 ,  A61P9/10 ,  A61P35/00 ,  C07C311/03 ,  C07C311/04 ,  C07C311/05 ,  C07C311/16 ,  C07C311/17 ,  C07C311/18 ,  C07C311/19 ,  C07D257/04 ,  C07F9/09 ,  C07F9/38 ,  C07F9/6524

Abstract: Sulphonamide derivatives of the formula I … … in which R is a C1-4-alkyl or phenyl group which can be substituted by halogen atoms, trifluoromethyl or C1-4-alkyl groups, R is a hydrogen atom or a C1-4-alkyl group, A is one of the groups CHOR , C=O, C=S or C=N-OR where R is a hydrogen atom, a C1-4-alkyl, phenyl, benzyl or C1-4-acyl group and R is a hydrogen atom or a methyl group, B can be a meta or para methylene, ethylene or, if A is not a carbonyl group, a methyleneoxy group, where the oxygen atom is bonded to the aromatic ring, E can be a carboxyl, phospho or sulpho radical, their physiologically suitable salts, esters with C1-4-alcohols and amides, and the tetrazol-5-yl radical, their preparation and use as pharmaceuticals.

公开(公告)号：DE3600275A1

公开(公告)日：1987-07-09

申请号：DE3600275

申请日：1986-01-08

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  SCHMIED BERNHARD DR ,  KROPP RUDOLF ,  BALDINGER VERENA DR ,  GRIES JOSEF DR MED ,  LEHMANN HANS DIETER PROF DR ,  RUEBSAMEN KLAUS DR ,  TRAUT MARTIN DR

IPC: C07D237/00 ,  A61K31/50 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D403/04 ,  C07D403/10 ,  A61K31/40

公开(公告)号：DE3535950A1

公开(公告)日：1987-04-09

申请号：DE3535950

申请日：1985-10-09

Applicant: BASF AG

Inventor： LEHMANN HANS DIETER PROF DR ,  KRETZSCHMAR ROLF PROF DR MED ,  HAHN KLAUS-JUERGEN PROF DR

IPC: A61K31/60 ,  A61K31/275 ,  A61K31/277 ,  A61P7/02 ,  A61K31/605

Abstract: A combination of verapamil, gallopamil or anipamil and acetylsalicylic acid in a weight ratio of from 10:1 to 2:1 being useful in the treatment of circulatory disorders.

公开(公告)号：DE3762970D1

公开(公告)日：1990-07-05

申请号：DE3762970

申请日：1987-01-03

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  SCHMIED BERNHARD DR ,  KROPP RUDOLF ,  BALDINGER VERENA DR ,  GRIES JOSEF DR ,  LEHMANN HANS DIETER PROF DR ,  RUEBSAMEN KLAUS DR ,  TRAUT MARTIN DR

IPC: C07D237/00 ,  A61K31/50 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D403/04 ,  C07D403/10

公开(公告)号：AT45674T

公开(公告)日：1989-09-15

申请号：AT86113453

申请日：1986-10-01

Applicant: BASF AG

Inventor： LEHMANN HANS DIETER PROF DR ,  KRETZSCHMAR ROLF PROF DR ,  HAHN KLAUS-JUERGEN PROF DR

IPC: A61K31/60 ,  A61K31/275 ,  A61K31/277 ,  A61P7/02 ,  A61K31/615

公开(公告)号：DE3425632A1

公开(公告)日：1986-01-16

申请号：DE3425632

申请日：1984-07-12

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  RASCHACK MANFRED DR ,  LEHMANN HANS DIETER PROF DR ,  GRIES JOSEF DR MED ,  RUEBSAMEN HANS DR ,  SCHMIED BERNHARD DR

IPC: A61K31/50 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D237/00 ,  C07D403/04 ,  C07D403/10 ,  C07D237/14 ,  A61K31/495

Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula I their preparation and their use in the treatment of disorders.