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1.发明申请
公开(公告)号：WO0064414A3
公开(公告)日：2001-05-31
申请号：PCT/EP0003232
申请日：2000-04-11
Applicant: BASF AG , HEGER ROBERT , SCHROF WOLFGANG , RIEGER JENS , VOELKEL RUEDIGER , BREITENBACH JOERG , ZEIDLER JUERGEN , LIEPOLD BERND , BERNDL GUNTHER , BINDER RUDOLF
Inventor： HEGER ROBERT , SCHROF WOLFGANG , RIEGER JENS , VOELKEL RUEDIGER , BREITENBACH JOERG , ZEIDLER JUERGEN , LIEPOLD BERND , BERNDL GUNTHER , BINDER RUDOLF
IPC: A61K47/22 , A61K9/16 , A61K31/4184 , A61K31/4439 , A61K45/00 , A61K47/34 , A61K47/42 , A61P1/00 , A61P1/04 , A61P35/00
CPC classification number: A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1658 , A61K31/4184 , A61K31/4439
Abstract: The invention relates to a solid preparation, containing an acid-sensitive proton-pump blocker as the active substance, whereby said active substance is present in an x-ray amorphous form and is embedded in molecularly dispersed form in an auxiliary agent matrix.
Abstract translation: 含有固体制剂，作为活性物质可使用酸不稳定的质子泵抑制剂，其特征在于所述活性物质是X射线无定形并且被嵌入在分子中的赋形剂基质中。
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2.发明申请MECHANICALLY STABLE PHARMACEUTICAL PRESENTATION FORM CONTAINING LIQUID OR SEMI-SOLID SURFACE-ACTIVE SUBSTANCES 审中-公开机械稳定的药物剂型含液体或半固体表面活性物质
公开(公告)号：WO0057854A3
公开(公告)日：2001-03-15
申请号：PCT/EP0002381
申请日：2000-03-17
Applicant: BASF AG , ROSENBERG JOERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JOERG
Inventor： ROSENBERG JOERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JOERG
IPC: A61K47/10 , A61K9/16 , A61K9/20 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
CPC classification number: A61K9/1617 , A61K9/1635 , A61K9/1694
Abstract: The invention relates to mechanically stable pharmaceutical presentation forms for peroral administration which in addition to one or more active ingredients and at least one thermoplastically mouldable matrix-forming auxiliary contain more than 10 and up to 40 % by weight of a surface-active substance which has an HLB of between 2 and 18 and is liquid at 20 DEG C or has a dropping point at between 20 and 50 DEG C.
Abstract translation: 使用涉及机械稳定的药物剂型经口给药，包括，除了一种或多种活性成分和至少一种可熔融加工的基质形成赋形剂大于10和高达40重量具有2至18的HLB值的表面活性剂的％，其中 20℃下是液体或在20〜50℃的滴点
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公开(公告)号：DE19913692A1
公开(公告)日：2000-09-28
申请号：DE19913692
申请日：1999-03-25
Applicant: BASF AG
Inventor： ROSENBERG JOERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JOERG
IPC: A61K47/10 , A61K9/16 , A61K9/20 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
Abstract: The invention relates to mechanically stable pharmaceutical presentation forms for peroral administration which in addition to one or more active ingredients and at least one thermoplastically mouldable matrix-forming auxiliary contain more than 10 and up to 40 % by weight of a surface-active substance which has an HLB of between 2 and 18 and is liquid at 20 DEG C or has a dropping point at between 20 and 50 DEG C.
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公开(公告)号：AU8632298A
公开(公告)日：1999-02-22
申请号：AU8632298
申请日：1998-07-21
Applicant: BASF AG
Inventor： ZEIDLER JUERGEN , NEUMANN JOERG , LIEPOLD BERND , ROSENBERG JOERG , BERNDL GUNTHER , BREITENBACH JOERG , VOLLGRAF CHRISTIANE
Abstract: A fast-acting analgesic comprises as analgesic substance ibuprofen in an adjuvant matrix with a porous structure and a density of greater than 1 and up to 2.5 g/cm3.
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公开(公告)号：CA2298659C
公开(公告)日：2007-09-11
申请号：CA2298659
申请日：1998-07-21
Applicant: BASF AG
Inventor： NEUMANN JORG , LIEPOLD BERND , VOLLGRAF CHRISTIANE , ROSENBERG JORG , ZEIDLER JURGEN , BREITENBACH JORG , BERNDL GUNTHER
Abstract: The invention relates to a fast acting analgesic, containing ibuprofen as th e active analgesic substance in an auxiliary substance matrix, with a porous structure and a density of greater than 1 - 2.5 g/cm3.
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Patent Agency Ranking
公开(公告)号：BR0012735A
公开(公告)日：2005-02-22
申请号：BR0012735
申请日：2000-04-11
Applicant: BASF AG
Inventor： HEGER ROBERT , SCHROF WOLFGANG , RIEGER JEANS , VOELKEL RUEDIGER , BREITTENBACH JOERG , ZEIDLER JUERGEN , LIEPOLD BERND , BERNDL GUNTHER , BINDER RUDOLF
IPC: A61K47/22 , A61K9/16 , A61K31/4184 , A61K31/4439 , A61K45/00 , A61K47/34 , A61K47/42 , A61P1/00 , A61P1/04 , A61P35/00
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公开(公告)号：EA002853B1
公开(公告)日：2002-10-31
申请号：EA200000132
申请日：1998-07-21
Applicant: BASF AG
Inventor： ZEIDER JURGEN , NEUMANN JORG , LIEPOLD BERND , ROSENBERG JOERG , BERNDL GUNTHER , BREITENBACH JORG , VOLLGRAF CHRISTIANE
Abstract: Настоящееизобретениеотноситсяк быстродействующемуобезболивающемупрепарату, содержащемув качествеобезболивающеговеществаибупрофенв матрицевспомогательныхвеществи имеющемупористуюструктуруи плотностьотболее 1 г/смидо 2,5 г/см. Изобретениетакжеотноситсяк способуполучениятакогопрепарата.
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公开(公告)号：CA2369951A1
公开(公告)日：2000-11-02
申请号：CA2369951
申请日：2000-04-11
Applicant: BASF AG
Inventor： SCHROF WOLFGANG , VOELKEL RUDIGER , ZEIDLER JURGEN , BINDER RUDOLF , HEGER ROBERT , BREITENBACH JORG , LIEPOLD BERND , BERNDL GUNTHER , RIEGER JENS
IPC: A61K47/22 , A61K9/16 , A61K31/4184 , A61K31/4439 , A61K45/00 , A61K47/34 , A61K47/42 , A61P1/00 , A61P1/04 , A61P35/00
Abstract: The invention relates to a solid preparation, containing an acid-sensitive proton-pump blocker as the active substance, whereby said active substance i s present in an x-ray amorphous form and is embedded in molecularly dispersed form in an auxiliary agent matrix.
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公开(公告)号：DE19918434A1
公开(公告)日：2000-10-26
申请号：DE19918434
申请日：1999-04-23
Applicant: BASF AG
Inventor： HEGER ROBERT , SCHROF WOLFGANG , RIEGER JENS , VOELKEL RUEDIGER , BREITENBACH JOERG , ZEIDLER JUERGEN , LIEPOLD BERND , BERNDL GUNTHER , BINDER RUDOLF
IPC: A61K47/22 , A61K9/16 , A61K31/4184 , A61K31/4439 , A61K45/00 , A61K47/34 , A61K47/42 , A61P1/00 , A61P1/04 , A61P35/00 , A61K31/415 , A61K9/14
Abstract: In a solid preparation (A) containing an acid-labile proton pump blocker (I) as active agent, (I) is in X-ray amorphous form and embedded in an auxiliary matrix. An Independent claim is included for the production of (A).
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公开(公告)号：CA2368138A1
公开(公告)日：2000-10-05
申请号：CA2368138
申请日：2000-03-17
Applicant: BASF AG
Inventor： BERNDL GUNTHER , LIEPOLD BERND , ROSENBERG JORG , BREITENBACH JORG
IPC: A61K47/10 , A61K9/16 , A61K9/20 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
Abstract: The invention relates to mechanically stable pharmaceutical presentation for ms for peroral administration which in addition to one or more active ingredien ts and at least one thermoplastically mouldable matrix-forming auxiliary contai n more than 10 and up to 40 % by weight of a surface-active substance which ha s an HLB of between 2 and 18 and is liquid at 20 ~C or has a dropping point at between 20 and 50 ~C.
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