-
公开(公告)号:WO2007118954A8
公开(公告)日:2008-12-04
申请号:PCT/FR2007000490
申请日:2007-03-23
Applicant: MAUNA KEA TECHNOLOGIES , ABRAT BENJAMIN , CAVE CHARLOTTE , LOISEAU ALEXANDRE , LOPEZ JEROME , OSDOIT ANNE , VIELLEROBE BERTRAND
Inventor: ABRAT BENJAMIN , CAVE CHARLOTTE , LOISEAU ALEXANDRE , LOPEZ JEROME , OSDOIT ANNE , VIELLEROBE BERTRAND
CPC classification number: A61B5/0071 , A61B1/043 , A61B1/07 , A61B5/0068 , A61B5/0084 , G01N21/6428 , G01N21/6458 , G01N2021/6484
Abstract: The invention relates to a method for the acquisition of in-vivo fluorescence imaging from a fabric using an acquisition system that includes at least one optical fibre exciting the fabric by scanning light beam. According to the invention, the system is used to detect fluorescence signals emitted by the Methylene Blue present in the fabric.
Abstract translation: 本发明涉及一种使用采集系统从织物获取体内荧光成像的方法,该采集系统包括通过扫描光束激发织物的至少一个光纤。 根据本发明,该系统用于检测由织物中存在的亚甲基蓝发射的荧光信号。
-
公开(公告)号:BR0215370A
公开(公告)日:2004-12-07
申请号:BR0215370
申请日:2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: BERIER FREDERIC , BOURRIAUX STEPHANE , GENET MAGALIE , VIELLEROBE BERTRAND , LOISEAU ALEXANDRE , ABRAT BENJAMIN
Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.
-
公开(公告)号:AT320614T
公开(公告)日:2006-04-15
申请号:AT02801158
申请日:2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: BERIER FREDERIC , BOURRIAUX STEPHANE , GENET MAGALIE , VIELLEROBE BERTRAND , LOISEAU ALEXANDRE , ABRAT BENJAMIN
Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.
-
公开(公告)号:FR2834348A1
公开(公告)日:2003-07-04
申请号:FR0116979
申请日:2001-12-28
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: BERIER FREDERIC , BOURRIAUX STEPHANE , GENET MAGALIE , VIELLEROBE BERTRAND , LOISEAU ALEXANDRE , ABRAT BENJAMIN
Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.
-
公开(公告)号:FR2834340A1
公开(公告)日:2003-07-04
申请号:FR0116981
申请日:2001-12-28
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: GENET MAGALIE , BOURG HECKLY GENEVIEVE , VILETTE SANDRINE , LACOMBE FRANCOIS , LOISEAU ALEXANDRE , ABRAT BENJAMIN
IPC: A61B1/00 , A61B5/00 , G01N21/64 , G01N33/483 , A61B1/07
Abstract: An equipment includes an excitation source ( 1 ), elements for injecting ( 2 ) an excitation signal produced by the source in an ordered bundle ( 3 ) of flexible optical fibers, elements for analyzing ( 21, 22 ) an emitted autofluorescence signal. The equipment also includes at the output of the optical fiber bundle ( 3 ) an optical head ( 4 ) designed to be placed in contact with the biological tissue ( 6 ), the optical head being equipped with optical elements adapted to cause the excitation signal output from the bundle ( 3 ) to converge into a subsurface analyzing zone ( 5 ), the same optical fiber(s) used for excitation of the bundle ( 3 ) being used for detecting the signal emitted by the subsurface analyzing zone, elements (D) placed upstream of the injection elements ( 2 ) being further provided to separate the wavelength of the excitation signal and the wavelength of the autofluorescence signal.
-
公开(公告)号:FR2899088B1
公开(公告)日:2008-06-27
申请号:FR0602793
申请日:2006-03-31
Applicant: MAUNA KEA TECHNOLOGIES SOC PAR
Inventor: ABRAT BENJAMIN , CAVE CHARLOTTE , LOISEAU ALEXANDRE , LOPEZ JEROME , OSDOIT ANNE , VIELLEROBE BERTRAND
Abstract: The method involves utilizing a confocal endo-microscopy system for detecting fluorescence signals emitted by methylene blue injected into a sample (13) e.g. biological tissue, where the system has an image guide (6) constituted of a flexible optical fiber for exciting the tissue by scanning a light beam e.g. laser beam. The light beam has wavelength ranging between 600-680 nanometers, and the methylene blue has a concentration ranging between 0.1-0.01 percentages.
-
公开(公告)号:FR2834340B1
公开(公告)日:2004-07-16
申请号:FR0116981
申请日:2001-12-28
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: GENET MAGALIE , BOURG HECKLY GENEVIEVE , VILETTE SANDRINE , LACOMBE FRANCOIS , LOISEAU ALEXANDRE , ABRAT BENJAMIN
IPC: A61B1/00 , A61B5/00 , G01N21/64 , G01N33/483 , A61B1/07
Abstract: An equipment includes an excitation source ( 1 ), elements for injecting ( 2 ) an excitation signal produced by the source in an ordered bundle ( 3 ) of flexible optical fibers, elements for analyzing ( 21, 22 ) an emitted autofluorescence signal. The equipment also includes at the output of the optical fiber bundle ( 3 ) an optical head ( 4 ) designed to be placed in contact with the biological tissue ( 6 ), the optical head being equipped with optical elements adapted to cause the excitation signal output from the bundle ( 3 ) to converge into a subsurface analyzing zone ( 5 ), the same optical fiber(s) used for excitation of the bundle ( 3 ) being used for detecting the signal emitted by the subsurface analyzing zone, elements (D) placed upstream of the injection elements ( 2 ) being further provided to separate the wavelength of the excitation signal and the wavelength of the autofluorescence signal.
-
公开(公告)号:CA2471724C
公开(公告)日:2012-03-13
申请号:CA2471724
申请日:2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: BERIER FREDERIC , BOURRIAUX STEPHANE , GENET MAGALIE , VIELLEROBE BERTRAND , LOISEAU ALEXANDRE , ABRAT BENJAMIN
Abstract: Elle est prévue pour équiper l'extrémité distale d'un faisceau de fibres optiques souples (2), destinée à venir au contact d'une surface d'analyse et comprenant des moyens optiques (3) pour focaliser un signal d'excitation en un point focal dit d'excitation situé à une profondeur donnée sous la surface d'analyse et pour prélever un signal rétroémis par le point focal d'excitation qui est véhiculé en retour par ledit faisceau de fibres. Elle est caractérisée par un tube porte-optique (4) au sein duquel sont introduits d'un côté la partie terminale distale (1) du faisceau de fibres (2) et de l'autre les moyens optiques, ces derniers comprenant une lame (21) placée au contact de l'extrémité (14) du faisceau de fibres dont l'indice est proche de celui du coeur des fibres et un bloc optique de focalisation (3), un hublot de sortie (30) étant en outre prévu adapté à réaliser une adaptation d'indice de manière à s'affranchir de la réflexion parasite s'opérant sur la surface d'analyse.
-
公开(公告)号:CA2647688A1
公开(公告)日:2007-10-25
申请号:CA2647688
申请日:2007-03-23
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: OSDOIT ANNE , LOPEZ JEROME , LOISEAU ALEXANDRE , CAVE CHARLOTTE , VIELLEROBE BERTRAND , ABRAT BENJAMIN
Abstract: L'invention concerne un procédé d'acquisition d'imagerie de fluorescence, in vivo, d'un tissu au moyen d'un système d'acquisition comprenant au moins une fibre optique d'excitation du tissu par balayage d'un faisceau lumineux. Sel on l'invention, on utilise le système pour la détection de signaux de fluorescence émis par du Bleu de Méthylène présent dans le tissu.
-
公开(公告)号:DE60209942T2
公开(公告)日:2006-11-30
申请号:DE60209942
申请日:2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: BERIER FREDERIC , BOURRIAUX STEPHANE , GENET MAGALIE , VIELLEROBE BERTRAND , LOISEAU ALEXANDRE , ABRAT BENJAMIN
Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.
-
-
-
-
-
-
-
-
-