公开(公告)号：EP2981249A1

公开(公告)日：2016-02-10

申请号：EP14778464.9

申请日：2014-04-02

Applicant: STC.UNM ,  Sandia Corporation

Inventor： CARNES, Eric C. ,  BRINKER, C. Jeffrey ,  ASHLEY, Carlee Erin

IPC: A61K9/16 ,  A61K47/48 ,  A61K38/20 ,  A61K49/04

CPC classification number: A61K39/39 ,  A61K9/127 ,  A61K9/146 ,  A61K9/5115 ,  A61K9/5184 ,  A61K31/365 ,  A61K38/19 ,  A61K39/0208 ,  A61K39/07 ,  A61K39/08 ,  A61K45/06 ,  A61K47/6923 ,  A61K47/6929 ,  A61K2039/55505 ,  A61K2039/55555 ,  A61K2300/00

Abstract: The present invention relates to mesoporous alum nanoparticles which can be used as a universal platform for antigen adsorption, presentation and delivery to provide immune compositions, including vaccines and to generate an immune response (preferably, both humoral and cell mediated immune response), preferably a heightened immune response to the presentation of one or more antigens to a patient or subject.

公开(公告)号：EP2782672A1

公开(公告)日：2014-10-01

申请号：EP12852129.1

申请日：2012-11-21

Applicant: STC.UNM ,  Luhrs, Claudia, Catalina ,  Brosha, Eric ,  Phillips, Jonathan

Inventor： LUHRS, Claudia, Catalina ,  BROSHA, Eric ,  PHILLIPS, Jonathan

IPC: B01J37/08 ,  B01J23/44 ,  B01J23/40 ,  B01J6/00

CPC classification number: B01J23/42 ,  B01J21/04 ,  B01J21/063 ,  B01J21/18 ,  B01J23/44 ,  B01J23/745 ,  B01J23/755 ,  B01J35/002 ,  B01J35/006 ,  B01J35/0093 ,  B01J35/1014 ,  B01J35/1028 ,  B01J37/0036 ,  B01J37/04 ,  B01J37/16 ,  H01M4/88 ,  H01M4/8842 ,  H01M4/9041 ,  H01M4/925 ,  H01M4/926

Abstract: Provided is a method for making a supported metal catalyst. The method includes forming a mixture comprising a high surface area support, a reducing agent precursor that decomposes to produce reducing gases below about 1200 °C, and a metal catalyst precursor. The mixture is heated to a temperature sufficient to decompose the reducing agent precursor to produce a reducing agent, and then cooled to form the supported metal catalyst.

公开(公告)号：EP1354338B1

公开(公告)日：2012-11-14

申请号：EP01981320.3

申请日：2001-09-21

Applicant: STC.UNM

Inventor： STINTZ, Andreas ,  VARANGIS, Petros, N. ,  MALLOY, Kevin, J. ,  LESTER, Luke, F. ,  NEWELL, Timothy, C. ,  LI, Hua

IPC: H01S5/34 ,  H01S5/12 ,  H01S5/14

CPC classification number: B82Y30/00 ,  B82Y10/00 ,  B82Y20/00 ,  H01S5/1228 ,  H01S5/143 ,  H01S5/183 ,  H01S5/3201 ,  H01S5/34 ,  H01S5/341 ,  H01S5/3412 ,  H01S5/4031 ,  H01S5/4043 ,  H01S5/4087

公开(公告)号：EP2498848A2

公开(公告)日：2012-09-19

申请号：EP10830835.4

申请日：2010-11-12

Applicant: STC.UNM

Inventor： SMYTH, Hugh, D.C. ,  SELVAM, Parthiban ,  TRUMAN, Charles, Randall

IPC: A61M15/00 ,  A61M11/02

CPC classification number: A61M15/0028 ,  A61M11/003 ,  A61M15/0031 ,  A61M15/0038 ,  A61M15/0086 ,  A61M2202/064 ,  A61M2205/0233 ,  A61M2206/16

Abstract: A dry powder inhaler including a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and a flutter element in the chamber and associated with a dose of powdered medicament. The flutter element has a tensioned distal end proximate the at least one airflow inlet and a free proximal end opposite to the distal end and downstream of the inlet. The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.

公开(公告)号：EP2470167A2

公开(公告)日：2012-07-04

申请号：EP10815900.5

申请日：2010-08-27

Applicant: STC.UNM

Inventor： SMYTH, Hugh, D.C. ,  DONOVAN, Martin, J.

IPC: A61K9/28 ,  A61K9/14 ,  A61K9/12

CPC classification number: A61K9/0075 ,  A61K9/14 ,  A61K31/58

Abstract: A method of method of coating powdered medical agent onto a carrier particle for use in a dry powder inhaler may include applying ultrasonic energy to agglomerated powdered medical agent to deaggregate and aerosolize particles of the medical agent into particles having a desired average particle size, and coating at least one carrier particle with a desired amount of the deaggregated and aerosolized particles of the medical agent.

公开(公告)号：EP2294147A2

公开(公告)日：2011-03-16

申请号：EP09814933.9

申请日：2009-06-30

Applicant: STC.UNM

Inventor： KISSEL, David, J. ,  BRINKER, Charles, Jeffrey

IPC: C09D133/04 ,  C09D183/02 ,  C09D5/00 ,  B05D5/00 ,  B05D7/00

CPC classification number: C09D7/1225 ,  A01N55/00 ,  C08K3/36 ,  C08K9/06 ,  C09D5/006 ,  C09D5/14 ,  C09D5/165 ,  C09D5/1681 ,  C09D7/62 ,  C09D133/12 ,  D06N3/0043 ,  D06N3/0063 ,  D10B2401/10 ,  D10B2401/13 ,  Y10T428/249953 ,  Y10T428/249972 ,  Y10T428/24999 ,  Y10T428/249991 ,  Y10T442/20

Abstract: Provided are polymer-aerogel composite coatings, devices and articles including polymer-aerogel composite coatings, and methods for preparing the polymer-aerogel composite. The exemplary article can include a surface, wherein the surface includes at least one region and a polymer-aerogel composite coating disposed over the at least one region, wherein the polymer-aerogel composite coating has a water contact angle of at least about 140° and a contact angle hysteresis of less than about 1°. The polymer-aerogel composite coating can include a polymer and an ultra high water content catalyzed polysilicate aerogel, the polysilicate aerogel including a three dimensional network of silica particles having surface functional groups derivatized with a silylating agent and a plurality of pores.

公开(公告)号：EP2281188A2

公开(公告)日：2011-02-09

申请号：EP09770680.8

申请日：2009-06-01

Applicant: STC.UNM

Inventor： CHEN, Jingkuang

IPC: G01N29/00 ,  G01N21/00 ,  A61B8/00

CPC classification number: A61B5/0095 ,  A61B5/0048 ,  A61B5/0091 ,  A61B5/0093 ,  A61B5/4312 ,  A61B8/44 ,  A61B8/4444 ,  A61B8/4483 ,  A61B8/483 ,  A61B2562/02 ,  A61B2562/028 ,  G01N21/1702 ,  G01N29/24 ,  G01N29/2406 ,  G01N29/2418 ,  G01N2021/1706 ,  G01N2291/02475 ,  G01N2291/106

Abstract: A photoacoustic imaging device includes an array of light sources configured and arranged to illuminate a target region and an array of ultrasonic transducers between the array of light sources and the target region. The array of transducers may be fixedly coupled to the array of light sources, and the array of ultrasonic transducers may be configured and arranged to receive ultrasound transmissions from the target region.

公开(公告)号：EP1993645A2

公开(公告)日：2008-11-26

申请号：EP07752039.3

申请日：2007-03-01

Applicant: STC.UNM

Inventor： SMYTH, Hugh ,  TRUMAN, Charles, Randall

IPC: A61M15/00

CPC classification number: A61M15/0065 ,  A61M15/0003 ,  A61M15/001 ,  A61M15/0028 ,  A61M15/0043 ,  A61M15/0045 ,  A61M15/0051 ,  A61M15/0055 ,  A61M15/0068 ,  A61M2202/064 ,  A61M2205/8275 ,  A61M2206/14 ,  A61M2206/16

Abstract: The present invention comprises a dry powder inhaler (DPI) that uses a patient's inhalation flow to concentrate energy in an aeroelastic element for deaggregation and dispersion of a powder dose. The result is a DPI that delivers a dose independent of inspiratory abilities of the patient, solving a major problem of conventional DPIs. Increased tension on the aeroelastic element causes higher frequency vibrations and improved powder dispersion. The tension of the aeroelastic element can be modified prior to dispensing the DPI to the patient, allowing for individualization for single patients or groups of patients. In addition, the DPI has features that increase the turbulence of the airflow as it passes through the device, further increasing the dispersion and deaggregation of the powder. The DPI can hold a single dose or multiple doses. The powder doses can be dispensed directly onto the aeroelastic element, or may be in adjacent blister packaging.

公开(公告)号：EP3055431B1

公开(公告)日：2020-06-24

申请号：EP14852570.2

申请日：2014-09-24

Applicant: STC.UNM

Inventor： EDWARDS, Jeremy Scott

IPC: C12Q1/6853 ,  C12Q1/689

公开(公告)号：EP3074134B1

公开(公告)日：2020-03-18

申请号：EP14865949.3

申请日：2014-11-26

Applicant: STC.UNM

Inventor： BRUECK, Steven, R.J. ,  EDWARDS, Jeremy, Scott ,  NEUMANN, Alexander ,  KUZNETSOVA, Yuliya ,  MENDOZA, Edgar, A.

IPC: B01L7/00 ,  C12M1/34 ,  C12Q1/68 ,  G01N33/487