公开(公告)号：CA2115277A1

公开(公告)日：1993-02-18

申请号：CA2115277

申请日：1992-08-05

Applicant: BASF AG

Inventor： MISSLITZ ULF DR ,  MEYER NORBERT DR ,  KAST JUERGEN DR ,  BRATZ MATTHIAS DR ,  HARREUS ALBRECHT DR ,  WALTER HELMUT DR ,  WESTPHALEN KARL-OTTO DR ,  GERBER MATTHIAS DR

IPC: A01N31/06 ,  A01N35/10 ,  A01N39/00 ,  A01N41/10 ,  A01N43/08 ,  A01N43/10 ,  A01N43/36 ,  A01N43/80 ,  A01P13/00 ,  C07C317/30 ,  C07C323/47 ,  C07D261/08 ,  C07D333/16 ,  C07D333/28 ,  A01N53/00 ,  C07D333/22

Abstract: 2115277 9303010 PCTABScor01 Cyclohexenone oximethers have the formula (I), in which n is 0 to 5; m is 0 to 2; R1 stands for C1-C6 alkyl; R2 stands for C1-C4 alkyl or benzyl; A stands for C1-C6 alkylene, C3-C6 alkenylene, C3-C6 alkinylene, C3-C6 alkylene or C4-C6 alkenylene chains, all these elements being optionally substituted. In each of them a methylene group may be substituted by O, S, SO, SO2 or -N(Ra)-; Ra stands for H, C1-C4 alkyl, C3-C6 alkenyl, C3-C6 alkinyl; Z stands for phenyl, 5-membered heteroaromate or 6-membered heteroaromate with 1 to 4 N atoms; X stands for NO2, CN, halogen, C1-C4 alkyl, C1-C4 halogenalkyl, C1-C4 alkoxy, C1-C4 alkylthio, C1-C4 halogenalkoxy, COOH, C1-C4 alkoxycarbonyl, optionally substituted benzyloxycarbonyl, optionally substituted phenyl, optionally substituted pyridyl, -NRbRc,; Rb stands for H, C1-C4 alkyl, C3-C6 alkenyl, C3-C6 alkinyl, Rc stands for H, C1-C4 alkyl, C3-C6 alkenyl, C3-C6 alkinyl C1-C6 acyl, optionally substituted benzoyl. The compounds having the formula (I), as well as their salts and esters of C1-C10 carboxylic and anorganic acids useful in agriculture, are suitable as herbicides.

公开(公告)号：DE4126479A1

公开(公告)日：1993-02-11

申请号：DE4126479

申请日：1991-08-09

Applicant: BASF AG

Inventor： MISSLITZ ULF DR ,  MEYER NORBERT DR ,  KAST JUERGEN DR ,  BRATZ MATTHIAS DR ,  HARREUS ALBRECHT DR ,  WALTER HELMUT DR ,  WESTPHALEN KARL-OTTO DR ,  GERBER MATTHIAS DR

IPC: A01N31/06 ,  A01N35/10 ,  A01N39/00 ,  A01N41/10 ,  A01N43/08 ,  A01N43/10 ,  A01N43/36 ,  A01N43/80 ,  A01P13/00 ,  C07C317/30 ,  C07C323/47 ,  C07D261/08 ,  C07D333/16 ,  C07D333/28

Abstract: Cyclohexenone oximethers have the formula (I), in which n is 0 to 5; m is 0 to 2; R stands for C1-C6 alkyl; R stands for C1-C4 alkyl or benzyl; A stands for C1-C6 alkylene, C3-C6 alkenylene, C3-C6 alkinylene, C3-C6 alkylene or C4-C6 alkenylene chains, all these elements being optionally substituted. In each of them a methylene group may be substituted by O, S, SO, SO2 or -N(R )-; R stands for H, C1-C4 alkyl, C3-C6 alkenyl, C3-C6 alkinyl; Z stands for phenyl, 5-membered heteroaromate or 6-membered heteroaromate with 1 to 4 N atoms; X stands for NO2, CN, halogen, C1-C4 alkyl, C1-C4 halogenalkyl, C1-C4 alkoxy, C1-C4 alkylthio, C1-C4 halogenalkoxy, COOH, C1-C4 alkoxycarbonyl, optionally substituted benzyloxycarbonyl, optionally substituted phenyl, optionally substituted pyridyl, -NR R ,; R stands for H, C1-C4 alkyl, C3-C6 alkenyl, C3-C6 alkinyl, R stands for H, C1-C4 alkyl, C3-C6 alkenyl, C3-C6 alkinyl C1-C6 acyl, optionally substituted benzoyl. The compounds having the formula (I), as well as their salts and esters of C1-C10 carboxylic and anorganic acids useful in agriculture, are suitable as herbicides.

公开(公告)号：DE4105518A1

公开(公告)日：1992-08-27

申请号：DE4105518

申请日：1991-02-22

Applicant: BASF AG

Inventor： MAYER HORST DR ,  HAMPRECHT GERHARD DR ,  WESTPHALEN KARL-OTTO DR ,  GERBER MATTHIAS DR ,  WALTER HELMUT DR

IPC: A01N47/36 ,  A01P13/00 ,  A61K47/36 ,  C07D239/42 ,  C07D239/46 ,  C07D239/47 ,  C07D239/52 ,  C07D251/42 ,  C07D251/46 ,  C07D251/52 ,  C07D521/00

Abstract: The invention concerns sulfonyl urea derivatives of formula (I), wherein R stands for optionally substituted alkyl or phenyl; alkenyl or propargyl; alkylamino or dialkylamino; R stands for hydrogen, halogen, optionally halogen-substituted methyl, methoxy or ethoxy, an alklylsulfonyl group, nitro or cyano; R stands for difluoromethoxy, trifluoromethoxy, bromodifluoromethoxy, chlorodifluoromethoxy or fluorine; R stands for halogen, optionally halogen-substituted methyl, ethyl, methoxy or ethoxy or the methylamino or dimethylamino group; R stands for hydrogen, alkyl, alkenyl or an alkinyl; Z stands for CH or N, provided that a) if R stands for the difluoromethoxy group, R does not stand for a di(alkyl)amino group, R does not stand for an alkylsulfonyl group, and R does not stand for a methyl or methoxy group, b) if R stands for a fluorine atom and Z stands for nitrogen, R does not stand for an alkylamino group. The invention also concerns their salts. The sulfonyl urea derivatives can be used as herbicides.

公开(公告)号：DE4039733A1

公开(公告)日：1992-06-17

申请号：DE4039733

申请日：1990-12-13

Applicant: BASF AG

Inventor： HAGEN HELMUT DR ,  NILZ GERHARD DR ,  WALTER HELMUT DR ,  LANDES ANDREAS DR

IPC: A01N43/56 ,  A01N25/32 ,  C07D231/38 ,  C07D231/40 ,  C07D309/12 ,  C07D335/02 ,  C07D403/04

Abstract: Substituted 5-aminopyrazols have formula (I), in which R stands for C1-C8-alkyl, C1-C8-hydroxyalkyl, phenyl, that can also carry 1-3 of the following residues: halogen, nitro, alkyl, halogen alkyl, alkoxy, halogen alkoxy, alkylthio or -NR R , and that can in addition carry as many halogen atoms as necessary for the total number of residues to be 5; R , R stand for H, C1-C4-alkyl; R stands for H, C1-C4-alkyl, C1-C4-halogen alkyl; R stands for CN, -CO-R , -CS-R ; R stands for OH, C1-C4-alkoxy, NH2, C1-C4-alkylamino, di-(C1-C4)-alkylamino; R , R stand for H, C1-C4-alkyl, -PX(OR )2, -SO2-R , -CX-R , -CX-NH-CY-R , CX-NH-SO2-R ; X, Y stand for O, S; R stands for one of the substituents named under R ; R stands for C1-C20-alkyl, C1-C4-alkoxy, if necessary substituted phenyl, NH2; R stands for NH2, C1-C4-alkylamino, di-(C1-C4)-alkylamino, pyrolidinyl, piperidinyl, morpholinyl; R and R together represent a group =CR R or -CO-W-CO; R stands for H, NH2, C1-C4-alkylamino or C3-C8-cycloalkylamino; R stands for NH2, C1-C4-alkylamino, di-(C1-C4)alkylamino, C3-C8-cacloalkylamino, pyrrolidin-1-yl, pipieridin-1-yl, morpholin-4-yl, if necessary substituted phenyl or pyridyl; W stands for an ethylene or ethenylene bridge, if necessary substituted, a 5 or 6 membered, 1,2-C linked aromatic or heteroaromatic bridge, if necessary substituted, or a 5 or 6 membered, 1,2-C linked cycloalkylene or cycloalkenylene bridge, if necessary substituted. Also disclosed are the basic salts of such compounds (I), in which R stands for a hydroxycarbonyl or hydroxythiocarbonyl group, and the acid salts of such compounds (I), containing a basic nitrogen atom, with the exception of 1-phenyl- and 1-methyl-4-cyano-5-(acylamino)-pyrazol, 1-methyl-4-cyano-5-(chloromethylcarbonylamino)-pyrazol, 1-methyl-4-cyano-5-(phenylcarbonylamino)-pyrazol, 1-methyl-4-cyano-5-(p-chlorophenylcarbonylamino)-pyrazol, as well as the compounds (I), in which R stands for a methyl, phenyl, 4-chlorophenyl or 4-nitrophenyl group, R stands for hydrogen, a methyl or trifluoromethyl group, R stands for a cyano group and R and R simultaneously stand for hydrogen. Also disclosed are herbicides that contain 2-(4-heteroaryloxy)- and 2-(4-aryloxy)- phenoxyacetic acid or propionic acid derivatives and/or cyclohexenone derivatives as herbicidal active substances and substituted 5-aminopyrazols I' as antidotes, as well as the salts of I', if acid terminal groups or basic nitrogen atoms are present.

公开(公告)号：DE4033193A1

公开(公告)日：1992-04-23

申请号：DE4033193

申请日：1990-10-19

Applicant: BASF AG

Inventor： KAST JUERGEN DR ,  MEYER NORBERT DR ,  MISSLITZ ULF DR ,  HARREUS ALBRECHT DR ,  RANG HARALD DR ,  GERBER MATTHIAS DR ,  WALTER HELMUT DR ,  WESTPHALEN KARL-OTTO DR

IPC: A01N35/10 ,  A01N43/14 ,  A01N49/00 ,  C07C239/20 ,  C07C251/42 ,  C07C251/52 ,  C07C317/28 ,  C07C323/47 ,  C07D213/30 ,  C07D261/08 ,  C07D307/12 ,  C07D309/06 ,  C07D309/22 ,  C07D309/28 ,  C07D317/26 ,  C07D333/22 ,  C07D339/06 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12

Abstract: 1-Oxo-3-hydroxy-2-cyclohexenyl ketoxime ethers of formula (I) are new. In (I) Q is H, 2-7 alkanoyl, benzoyl, alkali(ne earth) metal, opt. substd. ammonium, phosphonium, sulphonium, sulphoxonium or transition metal; W is CC or CH=CH; R1 is (a) alkoxyalkyl or alkylthioalkyl, (b) cycloalkyl, cycloalkenyl or 6-membered heterocyclyl contg. 1-2 nonadjacent O and/or S atoms, opt. substd. by 1-3 of OH, halogen, alkyl, haloalkyl, alkoxy or alkylthio, (c) 5-membered satd. heterocyclyl contg. 1-2 O and/or S atoms, opt. substd. by 1-3 of alkyl, haloalkyl, alkoxy or alkylthio, (d) 5-membered heteroaryl contg. 1-2 N atoms and/or an O or S atom, opt. substd. by 1-3 of CN, halogen, alkyl, haloalkyl, alkenyl, haloalkenyl, alkoxy, alkylthio, alkenyloxy or alkoxyalkyl, (e) phenyl or pyridyl opt. substd. by 1-3 of NO2, CN, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, alkoxyalkyl, alkylthioalkyl, alkenyloxy, alkynyloxy or NR8R9, or (f) R7X-substd. alkyl, where X is O, S, SO, or SO2 and R7 is alkyl, or phenyl or 5- or 6- membered heteroaryl opt. substd. as in (e); R8 is H, alkyl, alkenyl or alkynyl; R9 is H, alkyl, alkenyl, alkynyl, alkanoyl, or benzoyl opt. substd. by 1-3 of NO2, CN, halogen, alkyl, haloalkyl, alkoxy or alkylthio; R2 is alkyl; R3 is H or alkyl; R4 is H, halogen or alkyl; R5 is H or alkyl; or R3+R4, R3+R5 or R4+R5 are each alkylene or alkenylene; R6 is (a) H, alkyl, haloalkyl, phenylhaloalkyl, alkenyl, alkoxyalkyl or alkylthioalkyl, (b) cycloalkyl or cycloalkenyl, opt. substd. by 1-3 of OH, alkyl, haloalkyl, alkoxy, alkoxyalkyl or alkylthioalkyl or (c) phenyl or pyridyl opt. substd. by 1-3 of NO2, CN, OH, halogen, alkyl, haloalkyl, alkoxy, alkylthio, alkoxyalkyl or alkylthioalkyl. (B) Intermediates of formula (IIa) and (IIIa) are also new.

公开(公告)号：DE4023048A1

公开(公告)日：1992-01-23

申请号：DE4023048

申请日：1990-07-20

Applicant: BASF AG

Inventor： MUENSTER PETER DR ,  FREUND WOLFGANG DR ,  STEINER GERD DR ,  WALTER HELMUT DR ,  WESTPHALEN KARL-OTTO DR ,  GERBER MATTHIAS DR

IPC: A01N43/36 ,  A01N43/90 ,  C07D307/68 ,  C07D333/38 ,  C07D333/40 ,  C07D409/04 ,  C07D409/12 ,  C07D491/04 ,  C07D491/048 ,  C07D495/04

Abstract: Dicarboximides of the general formula Ia and Ib ulfur, R1 is hydrogen, cycloalkyl, alkyl, hydroxyl, alkoxy, cyanoalkyl, alkenyl, alkynyl, phenyl, naphthyl or a 5-membered or 6-membered heterocyclic structure, where the stated radicals may be substituted, and R2 and R3 are each nitro, cyano, halogen, amino, mono- or dialkylamino, alkylcarbonylamino, unsubstituted or halogen-substituted alkoxy or alkylthio, alkylsulfonyl, haloalkylsulfonyl, alkenyl, alkynyl, phenyl, phenoxy or phenylthio or one of the radicals R1, with the proviso that specific compounds named in the description are excluded. Processes for the preparation of the compounds Ia and Ib and herbicides containing them.

公开(公告)号：DE3926055A1

公开(公告)日：1991-02-14

申请号：DE3926055

申请日：1989-08-07

Applicant: BASF AG

Inventor： GROSSMANN KLAUS DR ,  WALTER HELMUT DR ,  WUERZER BRUNO DR

IPC: A01N33/00 ,  A01N33/18 ,  A01N33/22 ,  A01N37/48 ,  A01N41/08

Abstract: The use of diphenyl ether derivatives of the general formula I (I) where A is a radical where R1 is hydrogen, an alkali metal or alkaline earth metal ion, substituted or unsubstituted ammonium, alkyl of from 1 to 4 carbon atoms or alkoxycarbonylalkyl of a total of 1 to 6 carbon atoms and R2 is alkyl of from 1 to 4 carbon atoms, for the desiccation and abscission of plant organs.

公开(公告)号：HU228459B1

公开(公告)日：2013-03-28

申请号：HU0001493

申请日：1998-01-08

Applicant: BASF AG

Inventor： KARDORFF UWE DR ,  RHEINHEIMER JOACHIM DR ,  WALTER HELMUT DR ,  VON DEYN WOLFGANG DR ,  BAUMANN ERNST DR ,  MISSLITZ ULF DR ,  HILL REGINA LUISE DR ,  OTTEN MARTINA DR ,  ENGEL STEFAN ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  WITSCHEL MATTHIAS ,  WESTPHALEN KARL-OTTO DR ,  MAYER GUIDO ,  GOETZ NORBERT DR

IPC: C07D277/10 ,  C07D413/10 ,  A01N43/72 ,  A01N43/76 ,  A01N43/78 ,  A01N43/80 ,  C07D231/20 ,  C07D237/00 ,  C07D261/00 ,  C07D261/04 ,  C07D261/20 ,  C07D263/10 ,  C07D273/00 ,  C07D277/20 ,  C07D277/34 ,  C07D291/04 ,  C07D311/00 ,  C07D403/10 ,  C07D417/10 ,  C07D419/10 ,  C07D498/10

Abstract: Benzoyl derivatives of the formula I where the variables have the following meanings: R1, R2 are hydrogen, nitro, halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl or C1-C6-haloalkylsulfonyl; R3 is hydrogen, halogen or alkyl; R4, R5 are hydrogen, halogen, cyano, nitro, alkyl, alkoxy, alkylthio, dialkylamino, phenyl or carbonyl, it being possible for the 6 last-mentioned radicals to be substituted; X is O, S, NR9, CO or CR10R11; Y is O, S, NR12, CO or CR13R14; R15 is pyrazole which is unsubstituted or substituted, linked in the 4-position and has attached to it in the 5-position a hydroxyl or sulfonyloxy radical; and the agriculturally useful salts thereof; processes and intermediates for the preparation of the 3-heterocyclyl-substituted benzoyl derivatives; compositions comprising them; and the use of these derivatives or compositions comprising them for controlling undesirable plants.

公开(公告)号：HU226012B1

公开(公告)日：2008-02-28

申请号：HU0002178

申请日：1998-01-08

Applicant: BASF AG

Inventor： RHEINHEIMER JOACHIM DR ,  WALTER HELMUT DR ,  BAUMANN ERNST DR ,  MISSLITZ ULF DR ,  OTTEN MARTINA DR ,  HILL REGINA LUISE ,  ENGEL STEFAN ,  VON DEYN WOLFGANG ,  WITSCHEL MATTHIAS ,  WAGNER OLIVER DR ,  WESTPHALEN KARL-OTTO DR ,  MAYER GUIDO

IPC: C07D277/10 ,  A01N43/18 ,  C07D413/10 ,  A01N43/48 ,  A01N43/56 ,  A01N43/72 ,  A01N43/76 ,  A01N43/78 ,  A01N43/80 ,  C07D231/20 ,  C07D231/24 ,  C07D261/04 ,  C07D261/20 ,  C07D263/10 ,  C07D273/00 ,  C07D277/20 ,  C07D277/34 ,  C07D291/04 ,  C07D401/10 ,  C07D403/10 ,  C07D405/10 ,  C07D409/10 ,  C07D411/10 ,  C07D417/10 ,  C07D419/10 ,  C07D498/10

Abstract: 4-(3-Heterocyclyl-benzoyl)-pyrazole derivatives (I) and their salts are new: R1, R3 = H; NO2; halo; CN; 1-6C alkyl, 1-6C alkoxy, 1-6C alkylthio, 1-6C alkylsulphinyl or 1-6C alkylsulphonyl optionally substituted by halo; H2NSO2; (1-6C alkyl)NHSO2; (1-6C alkyl)2NSO2; (1-6C alkyl)SO2NH-; (1-6C haloalkyl-SO2)NH-; (1-6C alkyl)(1-6C alkyl-SO2)N-; or (1-6C haloalkyl)(1-6C alkyl-SO2)N-; R2 = optionally substituted 5- or 6-membered heterocycle containing 1-4 O, S and/or N atoms; R6 = 1-6C alkyl; R7 = 1-6C alkyl; 3-6C alkenyl or 3-6C alkynyl optionally substituted by halo; 3-6C cycloalkyl; 1-6C alkylcarbonyl; 2-6C alkenylcarbonyl; 2-6C alkynylcarbonyl; 3-6C cycloalkylcarbonyl; 1-6C alkoxycarbonyl; 3-6C alkenyloxycarbonyl; 3-6C alkynyloxycarbonyl; 1-6C alkyl-NH-CO-; 3-6C alkenyl-NH-CO-; 3-6C alkynyl-NH-CO-; (1-6C alkyl)2N-CO-; (3-6C alkenyl)(1-6C alkyl)N-CO-carbonyl; (3-6C alkynyl)(1-6C alkyl)N-CO-; (1-6C alkoxy)(1-6C alkyl)N-CO-; (3-6C alkenyl)(1-6C alkoxy)N-CO-; (3-6C alkynyl)(1-6C alkoxy)N-CO-; (1-6C alkyl)2N-CS-; 1-6C alkoxyimino-1-6C alkyl; 1-6C alkylamino imino-1-6C alkyl; or di(1-6C alkylamino)imino-1-6C alkyl (alkyl, cycloalkyl and alkoxy groups are optionally substituted by 1 or more halo and/or by 1-3 CN, OH, 1-4C alkoxy, 1-4C alkylthio, di(1-4C alkyl)amino, 1-4C alkylcarbonyl, 1-4C alkoxycarbonyl, 1-4C alkoxy-1-4C alkoxycarbonyl, (1-4C alkyl)2N-1-4C alkoxycarbonyl, COOH, 1-4C alkyl-NH-CO-, (1-4C alkyl)2N-CO-, CONH2; 1-4C alkylcarbonyloxy or 3-6C cycloalkyl); or Ar; Ar-1-6C alkyl; Ar-CO-1-6C alkyl; Ar-CO-; Ar-O-CO-; Ar-NH-CO-; (1-6C alkyl)(Ar)N-CO-; or Ar-2-6C alkenylcarbonyl; Ar = phenyl or heterocyclyl optionally substituted by 1 or more halo and/or by 1-3 NO2, CN or 1-4C alkyl or 1-4C alkoxy (optionally substituted by halo), and R8 = H, 1-6C alkyl or 1-6C haloalkyl.

公开(公告)号：AT341207T

公开(公告)日：2006-10-15

申请号：AT04019639

申请日：1996-09-12

Applicant: BASF AG

Inventor： LANDES MAX DR ,  SIEVERNICH BERND ,  KIBLER ELMAR DR ,  NUYKEN WESSEL DR ,  WALTER HELMUT DR ,  WESTPHALEN KARL-OTTO DR ,  MAYER HORST DR ,  HADEN EGON DR ,  MULDER CHRISTIAAN DR ,  SCHOENHAMMER ALFONS DR ,  HAMPRECHT GERHARD DR

IPC: A01N47/36

Abstract: Herbicidal mixt. comprises: (a) at least one fluoro-substd. sulphonyl urea derivs. of formula (I) or their salts; and (b) at least one herbicide in a synergistic amt. selected from e.g. buthidazole or cyprazole; allidochlor (CDDA), benzoylprop-ethyl, bromobutide, chlorthiamid, dimepiperate, dimethenamid, diphenamid, etobenzanid (benzchlomet), flampropmethyl, fosamin, isoxaben, monalide, naptalame, pronamid (propyzamid) or propanil; bilanafos (bialophos), buminafos, glufosinate ammonium, glyphospate or sulfosate; amitrole, anilofos or mefenacet; 2,4-D, 2,4-DB, clomeprop, dichlorprop, dichlorprop-P, dichlorprop-P (2,4-DP-P), fenoprop (2,4,5-TP, fluoroxypyr, MCPA, MCPB, mecoprop, mecoprop-P, napropamide, napropanilide or triclopyr, or salts of these. Z = N or CH; R1 = 1-6C alkyl opt. substd. by 1-5 OMe, OEt, SO2Me; CN; Cl; F; SMe; or S(O)Me; halo; ER6; COOR8; NO2; S(O)oR9, SO2NR10R11,; or CONR10R11; E = O; S or NR7; R2 = H; 1-4C alkyl or 1-4C alkoxy opt. substd. by halo; 2-4C alkenyl; 2-4C alkynyl; halo; SO2Me; SO2Et; NO2; CN; or 1-4C alkylthio; R3 = F, CF3; CF2Cl; CF2H; OCF3; OCF2Cl; Cl (when R1 - CO2Me and R2 = F); Me (when R1 = CH2CF3 or CF2CF3); or OCF2H or OCF2Br (when R4 =- OCF3 or OCF2Cl); R4 = OMe; OEt; Me or Et opt. substd. by halo; SMe; SEt; NHMe; NHEt; N(1-2C alkyl)2; or halo; R5 = H, OMe; OEt; or 1-4C alkyl; R6 = 1-4C alkyl, 2-4C alkenyl, 2-4C alkynyl or 3-6C cycloalkyl opt. substd by 1-5 halo (except allyl, OCH2F, OCF2Cl or 2-Cl-Et) when E = O or S; or SO2Me, SO2Et, SO2CF3, SO2-allyl or SO2-propargyl when E = O or NR7; R7 = H; Me; or Et; R8 = 1-6C alkyl opt. mono-, di- or trisubstd. by halo, 1-4C alkoxy, 1-4C alkylthio, 1-4C haloalkoxy, 1-4C alkoxy-1-2C alkoxy, 3-7C cycloalkyl and/or Ph; 5-7C cycloalkyl opt. mono-, di- or trisubstd. by 1-4C alkyl; 3-6C alkenyl; or 3-6C alkynyl; R10 = H; OMe; OEt; or 1-6C alkyl; and R11 = 1-4C alkyl opt. substd by 1-4 halo or 1-4C alkoxy; or 3-6C cycloalkyl; or R10+R11 = 4-6C alkylene with 1 CH2 opt. replaced by O or 1-4C alkylimino; n = 0-3; and o = 1-2.