公开(公告)号：FR2865369A1

公开(公告)日：2005-07-29

申请号：FR0400579

申请日：2004-01-22

Applicant: CENTRE NAT RECH SCIENT ,  OBSERVATOIRE PARIS ,  MAUNA KEA TECHNOLOGIES ,  UNIV PARIS 7 DENIS DIDEROT ,  UNIV PARIS CURIE

Inventor： LACOMBE FRANCOIS ,  GENDRON ERIC ,  GLANC MARIE ,  LAFAILLE DAVID

IPC: A61B3/12 ,  G01B9/02 ,  A61B3/103 ,  A61B3/14

Abstract: The device has two identical prisms (A, B), and a plate (C) with parallel sides. The prisms have fast axes that are parallel to each other and to edges of the prisms. The axes of the prisms are perpendicular to a fast axis of a plate. A variable retardant effect is created, according to relation position of the prisms. The plate has same birefringence as cornea, and axis of the plate is perpendicular to that of the cornea. Independent claims are also included for the following: (A) a method of compensating corneal birefringence in examination of parts of an eye situated beyond cornea (B) an in-vivo tomography system for examining an eye, including corneal birefringence compensating device.

公开(公告)号：FR2864631A1

公开(公告)日：2005-07-01

申请号：FR0315628

申请日：2003-12-31

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： BERIER FREDERIC ,  PERCHANT AYMERIC

IPC: G06T5/50 ,  G02B6/06 ,  A61B1/07 ,  G06T5/00

Abstract: The method involves performing a set of acquisitions across an image guide (1). Each acquisition is performed for a given spatial offset at a distal end of the guide with respect to an optical head. Each acquired data is transformed in a scatter diagram and each diagram is readjusted with respect to a reference scatter diagram. A final image is reconstructed by superimposing readjusted diagram. Independent claims are also included for the following: (A) a device for enhancing resolution of confocal image acquired across an image guide (B) a system implementing confocal image resolution enhancing method.

公开(公告)号：FR2849218B1

公开(公告)日：2005-03-04

申请号：FR0216279

申请日：2002-12-20

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： BERIER FREDERIC ,  VIELLEROBE BERTRAND ,  GENET MAGALIE ,  LACOMBE FRANCOIS ,  SANTOS PEDRO

IPC: G02B21/00 ,  G02B23/24 ,  G02B26/08 ,  G02B26/10 ,  G02B6/35

Abstract: The confocal optical miniature head has optical convergers (12,13) to an excitation point (S) on a subsurface. There is a sweep system around the observation point. There is a mechanical microsystem (14a,14b) moving one of the lenses following an offset (DC) in two planes to obtain the sweep.

公开(公告)号：FR2834348B1

公开(公告)日：2004-02-27

申请号：FR0116979

申请日：2001-12-28

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： BERIER FREDERIC ,  BOURRIAUX STEPHANE ,  GENET MAGALIE ,  VIELLEROBE BERTRAND ,  LOISEAU ALEXANDRE ,  ABRAT BENJAMIN

IPC: G02B23/26 ,  A61B1/00 ,  G02B21/02 ,  A61B1/07

Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.

公开(公告)号：CA2491751A1

公开(公告)日：2004-01-29

申请号：CA2491751

申请日：2003-07-11

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： PERCHANT AYMERIC ,  BERIER FREDERIC ,  LE GOUALHER GEORGES

IPC: A61B1/04 ,  G06T5/00

Abstract: L'invention concerne un procede de traitement d'image acquise au moyen d'un guide constitué par une pluralité de fibres optiques. Selon l'invention, pou r chaque fibre optique, on isole sur l'image acquise une zone correspondante à cette fibre optique, on traite localement chaque zone de façon individuelle pour corriger le flux de photon détecté dans chaque fibre optique, puis on reconstruit l'image acquise en éliminant le motif dû aux fibres optiques. Le procédé comprend également un processus d'étalonnage permettant d'obtenir, pour chaque fibre optique et à partir d'une image d'étalonnage, un taux d'injection étalon qui va servir à la reconstruction des images acquises. Le procédé comprend également en premier lieu une étape de détection des fibres à partir d'une image témoin.

公开(公告)号：FR2842628A1

公开(公告)日：2004-01-23

申请号：FR0209100

申请日：2002-07-18

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： PERCHANT AYMERIC ,  LE GOUALHER GEORGES ,  BERIER FREDERIC

IPC: G06T5/00 ,  A61B1/04 ,  G06K9/78 ,  G02B6/06

Abstract: A method for processing an image acquired through a guide consisting of a plurality of optical fibers includes, for each optical fiber, isolating on the acquired image a zone corresponding to the optical fiber, locally processing each zone individually to correct the photon flux detected in each optical fiber, then reconstructing the acquired image by eliminating the pattern caused by the optical fiber. The method also includes a sampling process for obtaining, for each optical fiber and from a sampling image, a sample injection rate which can be used for reconstructing the acquired images. The method also includes a prior step which consists in detecting the fibers from a target.

公开(公告)号：FR2842407A1

公开(公告)日：2004-01-23

申请号：FR0209099

申请日：2002-07-18

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： GENET MAGALIE ,  VIELLEROBE BERTRAND ,  BERIER FREDERIC ,  CLADE SOPHIE

IPC: A61B1/00 ,  G01N21/64 ,  A61B1/04 ,  A61B5/00 ,  G02B21/00 ,  G02B23/24 ,  G02B23/26 ,  G02B26/10 ,  H04N1/028

Abstract: The method consists in deflecting the excitation signal at a speed corresponding to acquisition of a number of images per second sufficient for real time use and in detecting the fluorescence signal at a detecting frequency corresponding to a minimum frequency for sampling the fibers one by one. The method uses an image guide consisting of several thousands of optical fibers, an excitation signal being emitted by a source, deflected and injected by turns into the optical fibers of the guide, each excitation point of the tissue in the fiber output emitting in return a fluorescence signal collected by the fiber, then detected and digitized to form an image element. The method also provides for the focussing of the beam in the fiber output to excite a subsurface plane to produce a confocal image. The method also provides for the production of a divergent beam in the fiber output capable of exciting a micro-volume of the tissue from the surface.

公开(公告)号：AU2002364332A1

公开(公告)日：2003-07-30

申请号：AU2002364332

申请日：2002-12-20

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： GENET MAGALIE ,  BOURG-HECKLY GENEVIEVE ,  VILETTE SANDRINE ,  LACOMBE FRANCOIS ,  LOISEAU ALEXANDRE ,  ABRAT BENJAMIN

IPC: A61B1/00 ,  A61B5/00 ,  G01N21/64 ,  A61B1/04 ,  G02B23/26

Abstract: An equipment includes an excitation source ( 1 ), elements for injecting ( 2 ) an excitation signal produced by the source in an ordered bundle ( 3 ) of flexible optical fibers, elements for analyzing ( 21, 22 ) an emitted autofluorescence signal. The equipment also includes at the output of the optical fiber bundle ( 3 ) an optical head ( 4 ) designed to be placed in contact with the biological tissue ( 6 ), the optical head being equipped with optical elements adapted to cause the excitation signal output from the bundle ( 3 ) to converge into a subsurface analyzing zone ( 5 ), the same optical fiber(s) used for excitation of the bundle ( 3 ) being used for detecting the signal emitted by the subsurface analyzing zone, elements (D) placed upstream of the injection elements ( 2 ) being further provided to separate the wavelength of the excitation signal and the wavelength of the autofluorescence signal.

公开(公告)号：CA2491751C

公开(公告)日：2015-10-13

申请号：CA2491751

申请日：2003-07-11

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： PERCHANT AYMERIC ,  LE GOUALHER GEORGES ,  BERIER FREDERIC

IPC: A61B1/04 ,  G06T5/00

Abstract: L'invention concerne un procede de traitement d'image acquise au moyen d'un guide constitué par une pluralité de fibres optiques. Selon l'invention, pour chaque fibre optique, on isole sur l'image acquise une zone correspondante à cette fibre optique, on traite localement chaque zone de façon individuelle pour corriger le flux de photon détecté dans chaque fibre optique, puis on reconstruit l'image acquise en éliminant le motif dû aux fibres optiques. Le procédé comprend également un processus d'étalonnage permettant d'obtenir, pour chaque fibre optique et à partir d'une image d'étalonnage, un taux d'injection étalon qui va servir à la reconstruction des images acquises. Le procédé comprend également en premier lieu une étape de détection des fibres à partir d'une image témoin.

公开(公告)号：CA2561770C

公开(公告)日：2015-06-23

申请号：CA2561770

申请日：2005-03-25

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： LACOMBE FRANCOIS ,  LE GOUALHER GEORGES ,  PERCHANT AYMERIC ,  AYACHE NICHOLAS

IPC: G01S15/89 ,  A61B3/12 ,  G01F1/00 ,  G01F1/708 ,  G01N15/14 ,  G02B21/00

Abstract: L'invention concerne un procédé pour mesurer la vitesse d'une particule telle qu'un globule rouge en mouvement au sein d'un écoulement, tel qu'un flux sanguin, à partir d'un microscope à balayage lumineux, ce procédé comprenant les étapes suivantes: acquisition d'une image par balayage lumineux en x et y d'un plan contenant ledit objet; détection dans le plan (x, y) d'une strie engendrée par le déplacement dudit objet lors de l'acquisition de ladite image ; détermination de la pente de ladite strie dans le plan (x, y) ; estimation de la vitesse v g dudit objet à partir de la pente ainsi déterminée.