公开(公告)号：DK24984A

公开(公告)日：1984-07-23

申请号：DK24984

申请日：1984-01-20

Applicant: BASF AG

Inventor： ROSSY PHILLIP A ,  THYES MARCO ,  FRANKE ALBRECHT ,  KOENIG HORST ,  LEHMANN HANS DIETER ,  GRIES JOSEF ,  FRIEDRICH LUDWIG ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00 ,  C07D

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

公开(公告)号：CA1169862A

公开(公告)日：1984-06-26

申请号：CA372457

申请日：1981-03-06

Applicant: BASF AG

Inventor： MAY HANS-JOACHIM ,  LENKE DIETER ,  GRIES JOSEF ,  TESCHENDORF HANS-JUERGEN ,  WORSTMANN WOLFGANG

IPC: C07D409/06 ,  A61K31/33 ,  A61K31/415 ,  A61K31/465 ,  A61K31/47 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P43/00 ,  C07D233/54 ,  C07D233/64 ,  C07D401/06 ,  C07D403/06 ,  C07D405/06 ,  C07D413/06 ,  C07D417/06 ,  C07D233/50

Abstract: 1-Aroyl-2-phenylamino-2-imidazolines of the general formula where R1 and R2 are identical or different end each is chloroine, bromine, fluorine, methyl, ethyl, methoxy, trifluoromethyl or cyano, R3 has the meanings given for R1 and R2 or is hydrogen and Ar is an unsubstituted or substituted monocyclic or bicyclic heteroaromatic radical containing 1, 2 or 3 nitrogen and/or oxygen and/or sulfur atoms, their salts with physiologically tolerated acids, their preparation, and drugs containing these compounds The compounds have, inter alia, a blood pressurereducing action.

公开(公告)号：FI65616B

公开(公告)日：1984-02-29

申请号：FI810380

申请日：1981-02-10

Applicant: BASF AG

Inventor： THIEME PETER C ,  FRANKE ALBRECHT ,  LENKE DIETER ,  LEHMANN HANS DIETER ,  GRIES JOSEF

IPC: C07D413/12 ,  A61K31/495 ,  A61K31/496 ,  A61P9/12 ,  C07D271/10 ,  C07D405/12

Abstract: Novel phenylpiperazinylpropanols of 1,3,4-oxadiazolylphenols and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and are useful in the treatment of hypertonia.

公开(公告)号：FI840224A0

公开(公告)日：1984-01-19

申请号：FI840224

申请日：1984-01-19

Applicant: BASF AG

Inventor： ROSSY PHILLIP A ,  THYES MARCO ,  FRANKE ALBRECHT ,  KOENIG HORST ,  LEHMANN HANS DIETER ,  GRIES JOSEF ,  FRIEDRICH LUDWIG ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00 ,  C07D

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

公开(公告)号：AU532983B2

公开(公告)日：1983-10-20

申请号：AU6366780

申请日：1980-10-24

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  THIEME PETER C ,  FRANKE ALBRECHT ,  THEOBALD HANS ,  LENKE DIETER ,  GRIES JOSEF

IPC: A61K31/42 ,  A61P9/00 ,  A61P9/12 ,  A61P25/02 ,  C07C43/12 ,  C07C45/61 ,  C07C45/64 ,  C07C45/70 ,  C07D261/08 ,  C07F9/653 ,  C07D413/12 ,  E04F15/18

Abstract: Novel aminopropanol derivatives of 5-(2-hydroxystyryl)-isoxazole and their addition salts with acids, their preparation, pharmaceutical formulations containing these compounds, and their use in the treatment of hypertonia, coronary heart disease and cardiac arrhythmias.

公开(公告)号：AU8249082A

公开(公告)日：1983-04-21

申请号：AU8249082

申请日：1982-04-08

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETZSCHMAR ROLF ,  LEHMANN HANS DIETER ,  FRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER ,  TREIBER HANS GEORG ,  DENGEL FERDINAND ,  FRANK WOLFRAM ,  KURBJUWEIT HANS-GEORG ,  MUELLER CLAUS D

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18 ,  C07C121/78

公开(公告)号：NO147384C

公开(公告)日：1983-04-06

申请号：NO780388

申请日：1978-02-03

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  HAGEN HELMUT ,  OHNSORGE ULRICH ,  FRANKE ALBRECHT ,  LENKE DIETER ,  GRIES JOSEF ,  LEHMANN HANS DIETER

IPC: A61K31/428 ,  C07D275/04

Abstract: New aminopropanol derivatives of 4-hydroxy-1,2-benzisothiazole and their addition salts with acids, their preparation, and pharmaceutical formulations which contain the said compounds and may be used for the treatment and prophylaxis of cardiac and circulatory disorders.

公开(公告)号：ZA822416B

公开(公告)日：1983-03-30

申请号：ZA822416

申请日：1982-04-08

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETSZSCHMAR ROLF ,  LEHMANN HANS DIETER ,  FRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER ,  TREIBER HANS JOERG ,  DENGEL FERDINAND ,  FRANK WOLFRAM ,  KURBJUWEIT HANS GEORG ,  MUELLER CLAUS D

IPC: A61K31/275 ,  A61K20060101 ,  A61K31/335 ,  A61K31/357 ,  A61K31/36 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/06 ,  A61P9/12 ,  A61P37/08 ,  C07C20060101 ,  C07C67/00 ,  C07C253/00 ,  C07C255/42 ,  C07C313/00 ,  C07C323/25 ,  C07C323/62 ,  C07D317/58 ,  C07D319/08 ,  C07D319/18 ,  A61K ,  C07C

公开(公告)号：ZA82294B

公开(公告)日：1982-12-29

申请号：ZA82294

申请日：1982-01-18

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  STEINER GERD ,  THIEME PETER C ,  LENKE DIETER ,  GRIES JOSEF ,  TESCHENDORF HANS JUERGEN

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D233/88 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00 ,  A61K ,  C06D

Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.

公开(公告)号：ZA8200294B

公开(公告)日：1982-12-29

申请号：ZA8200294

申请日：1982-01-18

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  STEINER GERD ,  THIEME PETER C ,  LENKE DIETER ,  GRIES JOSEF ,  TESCHENDORF HANS JUERGEN

IPC: C07D249/08 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00 ,  A61K ,  C06D

CPC classification number: C07D231/12 ,  C07D233/56 ,  C07D239/42 ,  C07D249/08 ,  C07D261/08 ,  C07D295/088 ,  Y10S514/923