公开(公告)号：US09561003B2

公开(公告)日：2017-02-07

申请号：US14198074

申请日：2014-03-05

Applicant: Spectrx, Inc.

Inventor： Shabbir Bakir Bambot ,  Mark Faupel ,  Jonathan David Mongin

IPC: A61B5/00 ,  G01J3/02 ,  G01J3/10 ,  G01J3/28 ,  G01J3/44 ,  G01N21/27 ,  G01N21/31 ,  G01N21/47 ,  G01N21/64 ,  G01J3/12

CPC classification number: A61B5/4331 ,  A61B5/0059 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0077 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/0262 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/28 ,  G01J3/4406 ,  G01J2003/1213 ,  G01J2003/2866 ,  G01N21/274 ,  G01N21/31 ,  G01N21/474 ,  G01N21/645 ,  G01N2021/6417 ,  G01N2021/6423 ,  G01N2021/6484 ,  G01N2201/0221

Abstract: A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics and correlate same to photographic images. Further, the system and method accomplish this measurement rapidly by increasing the light throughput by integrating optics into a hand held unit and avoiding the need for a coherent fiber optic bundle being used. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.

Abstract translation: 提供了一种方法和装置，用于询问，接收和分析至少一种荧光激发波长的全发射光谱，以及至少一种反射测量以确定组织特征并将其与摄影图像相关联。 此外，该系统和方法通过将光学器件集成到手持式单元中并且避免对使用的相干光纤束的需要而增加光通量而快速地完成该测量。 该方法包括用光能照射目标组织的第一部分，形成目标组织的第一图像，用光能照射目标组织的第二部分，对目标反射和/或发射的光能进行光谱测量 基于光谱测量的结果确定目标组织的第二部分的光能量的组织，以及确定靶组织的组织特征。

公开(公告)号：US09513167B2

公开(公告)日：2016-12-06

申请号：US14579832

申请日：2014-12-22

Applicant: Thermo Scientific Portable Analytical Instruments Inc.

Inventor： Michael Derek Hargreaves ,  Timothy M. Pastore ,  Gregory H. Vander Rhodes ,  Brendon D. Tower

IPC: G01N21/00 ,  G01J3/44 ,  G01J3/02 ,  G01J3/28 ,  G01J3/45 ,  G01N21/35 ,  G01N21/65 ,  G01J3/453

CPC classification number: G01J3/4412 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/28 ,  G01J3/44 ,  G01J3/45 ,  G01J3/453 ,  G01J2003/2833 ,  G01N21/35 ,  G01N21/65 ,  G01N2021/3595 ,  G01N2201/0221

Abstract: A spectrometer configurable for field analyses of chemical properties of a material is provided. The spectrometer includes: at least one sensor adapted for providing Fourier transform infrared spectroscopy (FTIR) surveillance and at least another sensor for providing Raman spectroscopy surveillance. The spectrometer can be provided with a user accessible instruction set for modifying a sampling configuration of the spectrometer. A method of determining the most likely composition of a sample by at least two technologies using the spectrometer is also provided.

Abstract translation: 提供了可配置用于材料的化学性质的现场分析的光谱仪。 光谱仪包括：适于提供傅里叶变换红外光谱（FTIR）监视的至少一个传感器和用于提供拉曼光谱监视的至少一个传感器。 光谱仪可以设置有用于修改光谱仪的采样配置的用户可访问指令集。 还提供了通过使用光谱仪的至少两种技术来确定样品的最可能组成的方法。

公开(公告)号：US20140042322A1

公开(公告)日：2014-02-13

申请号：US14055554

申请日：2013-10-16

Applicant: ChemImage Corporation

Inventor： Patrick Treado ,  MATTHEW NELSON ,  CHARLES GARDNER, JR.

IPC: G01N21/25

CPC classification number: G01N21/25 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/10 ,  G01J3/26 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/44 ,  G01N21/31 ,  G01N21/6456 ,  G01N21/65 ,  G01N2021/3155 ,  G01N2021/6423 ,  G01N2201/0221 ,  G01N2201/129

Abstract: A portable system and method for detecting drug materials. A portable system may comprise at least one collection lens for collecting a plurality of interacted photons, a tunable filter for filtering the photons, and a SWIR detector for generating at least one SWIR data set representative of a first location comprising an unknown sample. A processor may analyze the SWIR data set to associate the unknown material with a known drug material. A method may comprise collecting a plurality of interacted photons, filtering the interacted photons into a plurality of wavelength bands, detecting the filtered photons to generate a SWIR data set and analyzing the SWIR data set to associate an unknown material with a known drug material.

Abstract translation: 一种用于检测药物材料的便携式系统和方法。 便携式系统可以包括用于收集多个相互作用的光子的至少一个收集透镜，用于滤波光子的可调滤波器，以及用于生成代表包含未知样本的第一位置的至少一个SWIR数据集的SWIR检测器。 处理器可以分析SWIR数据集以将未知材料与已知药物材料相关联。 方法可以包括收集多个相互作用的光子，将相互作用的光子过滤成多个波长带，检测滤波后的光子以产生SWIR数据集，并分析SWIR数据集以将未知材料与已知药物材料相关联。

公开(公告)号：US20130308317A1

公开(公告)日：2013-11-21

申请号：US13474206

申请日：2012-05-17

Applicant: Kenneth J. Vachon, JR. ,  Walter J. Doherty, III ,  Leonid Y. Krasnobaev ,  Scott E. Miller

Inventor： Kenneth J. Vachon, JR. ,  Walter J. Doherty, III ,  Leonid Y. Krasnobaev ,  Scott E. Miller

IPC: F21V15/01 ,  F21V5/04

CPC classification number: G01N21/359 ,  G01J3/0202 ,  G01J3/024 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0286 ,  G01J3/0291 ,  G01N21/01 ,  G01N21/031 ,  G01N2021/3595 ,  G01N2201/0221 ,  G01N2201/024

Abstract: In an embodiment, an apparatus includes a module assembly and a main assembly. The module assembly includes a module assembly housing, a first face plate and an analysis unit attached to the first face. The main assembly includes a main assembly housing, a second face plate and an engine unit rigidly attached to the second face plate. The engine unit generates a light that passes to the analysis unit via a first lens assembly and a second lens assembly. The first lens assembly is attached to the first face plate and the second lens assembly is attached to the second face plate. The module assembly when attached to the main assembly causes the first and second face plates to act as a single mechanical unit that moves independent of movement of the module assembly housing and/or the main assembly housing.

Abstract translation: 在一个实施例中，装置包括模块组件和主组件。 模块组件包括模块组件壳体，第一面板和附接到第一面的分析单元。 主组件包括主组件壳体，第二面板和刚性地附接到第二面板的发动机单元。 发动机单元产生经由第一透镜组件和第二透镜组件传递到分析单元的光。 第一透镜组件附接到第一面板，第二透镜组件附接到第二面板。 当附接到主组件时，模块组件使得第一和第二面板作为独立于模块组件壳体和/或主组件壳体的运动而移动的单个机械单元。

公开(公告)号：US08269174B2

公开(公告)日：2012-09-18

申请号：US12719904

申请日：2010-03-09

Applicant: Charles W. Gardner ,  Patrick J. Treado ,  Matthew Nelson ,  Robert Schweitzer

Inventor： Charles W. Gardner ,  Patrick J. Treado ,  Matthew Nelson ,  Robert Schweitzer

IPC: G01J5/02

CPC classification number: G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0256 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/44 ,  G01N21/31 ,  G01N21/6456 ,  G01N21/6486 ,  G01N21/65

Abstract: A method and a portable device for assessing the occurrence of an agent in a sample. A sample is illuminated with photons emanating from a portable device to produce photons reflected, emitted, or absorbed from a set of multiple points in the sample having a defined geometric relationship. The portable device is used to simultaneously illuminate the sample and analyze the photons reflected, emitted, or absorbed from the set of multiple points using spectroscopic methods, including infrared, fluorescence, and UV/visible. The agent assessed may include a hazardous agent, a chemical agent, a biological agent, a microorganism, a bacterium, a protozoan, a virus, and combinations thereof.

Abstract translation: 一种用于评估样品中的试剂的发生的方法和便携式装置。 用便携式设备发出的光子照射样品，以产生从具有确定的几何关系的样品中的一组多个点反射，发射或吸收的光子。 便携式设备用于同时照亮样品并使用包括红外，荧光和紫外/可见光在内的光谱方法分析从该组多个点反射，发射或吸收的光子。 所评估的试剂可以包括危险剂，化学试剂，生物制剂，微生物，细菌，原生动物，病毒及其组合。

公开(公告)号：US20120232404A1

公开(公告)日：2012-09-13

申请号：US13228717

申请日：2011-09-09

Applicant: Shabbir Bakir Bambot ,  Mark Faupel ,  Jonathan David Mongin

Inventor： Shabbir Bakir Bambot ,  Mark Faupel ,  Jonathan David Mongin

IPC: A61B6/00

CPC classification number: A61B5/4331 ,  A61B5/0059 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0077 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/0262 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/28 ,  G01J3/4406 ,  G01J2003/1213 ,  G01J2003/2866 ,  G01N21/274 ,  G01N21/31 ,  G01N21/474 ,  G01N21/645 ,  G01N2021/6417 ,  G01N2021/6423 ,  G01N2021/6484 ,  G01N2201/0221

Abstract: A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics and correlate same to photographic images. Further, the system and method accomplish this measurement rapidly by increasing the light throughput by integrating optics into a hand held unit and avoiding the need for a coherent fiber optic bundle being used. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.

Abstract translation: 提供了一种方法和装置，用于询问，接收和分析至少一种荧光激发波长的全发射光谱，以及至少一种反射测量以确定组织特征并将其与摄影图像相关联。 此外，该系统和方法通过将光学器件集成到手持式单元中并且避免对使用的相干光纤束的需要而增加光通量而快速地完成该测量。 该方法包括用光能照射目标组织的第一部分，形成目标组织的第一图像，用光能照射目标组织的第二部分，对目标反射和/或发射的光能进行光谱测量 基于光谱测量的结果确定目标组织的第二部分的光能量的组织，以及确定靶组织的组织特征。

公开(公告)号：US08184287B2

公开(公告)日：2012-05-22

申请号：US12547317

申请日：2009-08-25

Applicant: Mark A. Hamilton ,  John E. Goulter

Inventor： Mark A. Hamilton ,  John E. Goulter

IPC: G01N21/67 ,  G01N21/63

CPC classification number: G01J3/443 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0286 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/18

Abstract: An optical emission spectroscopic system contains multiple distinct light paths that provide increased light to a spectrometer, thereby increasing sensitivity and signal-to-noise of the system.

Abstract translation: 光发射光谱系统包含多个不同的光路，其向光谱仪提供增加的光，从而增加系统的灵敏度和信号对噪声。

公开(公告)号：US20110199606A1

公开(公告)日：2011-08-18

申请号：US12661419

申请日：2010-03-15

Applicant: Wayne D. Jung ,  Russell W. Jung ,  Alan R. Loudermilk

Inventor： Wayne D. Jung ,  Russell W. Jung ,  Alan R. Loudermilk

IPC: G01N21/00

CPC classification number: G01J3/51 ,  A61B5/0088 ,  A61B2560/0233 ,  A61B2562/247 ,  A61C19/10 ,  G01J1/04 ,  G01J1/0411 ,  G01J1/0437 ,  G01J1/0474 ,  G01J1/06 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0251 ,  G01J3/0259 ,  G01J3/0264 ,  G01J3/0278 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/508 ,  G01J3/513 ,  G01N21/474 ,  G01N21/57 ,  G07D7/1205 ,  G07D7/17

Abstract: Optical characteristic measuring systems and methods such as for determining the color or other optical characteristics of teeth are disclosed. Perimeter receiver fiber optics preferably are spaced apart from a source fiber optic and receive light from the surface of the object/tooth being measured. Light from the perimeter fiber optics pass to a variety of filters. The system utilizes the perimeter receiver fiber optics to determine information regarding the height and angle of the probe with respect to the object/tooth being measured. Under processor control, the optical characteristics measurement may be made at a predetermined height and angle. Various color spectral photometer arrangements are disclosed. Translucency, fluorescence, gloss and/or surface texture data also may be obtained. Audio feedback may be provided to guide operator use of the system. The probe may have a removable or shielded tip for contamination prevention. A method of producing dental prostheses based on measured data also is disclosed. Measured data also may be stored and/or organized as part of a patient data base. Such methods and implements may be desirably utilized for purposes of detecting and preventing counterfeiting or the like.

公开(公告)号：US20110075146A1

公开(公告)日：2011-03-31

申请号：US12569226

申请日：2009-09-29

Applicant: Nathan Moroney ,  Jeffrey M. DiCarlo ,  Steven W. Trovinger ,  Melanie M. Gottwals ,  Glen E. Montgomery ,  Carl E. Picciotto ,  Miheer Bhachech

Inventor： Nathan Moroney ,  Jeffrey M. DiCarlo ,  Steven W. Trovinger ,  Melanie M. Gottwals ,  Glen E. Montgomery ,  Carl E. Picciotto ,  Miheer Bhachech

IPC: G01J3/46

CPC classification number: G01J3/50 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/501 ,  G01J3/524

Abstract: A device includes a housing; a color sensor within a first end of the housing, the color sensor configured to sense a color of a sample when the color sensor is placed proximate the sample; and a display within the housing, the display configured to display the color of the sample sensed by the color sensor.

Abstract translation: 一种装置包括壳体; 在所述壳体的第一端内的颜色传感器，所述颜色传感器被配置为当所述颜色传感器靠近所述样品放置时感测样品的颜色; 以及在所述外壳内的显示器，所述显示器被配置为显示由所述颜色传感器感测到的样本的颜色。

公开(公告)号：US20100078564A1

公开(公告)日：2010-04-01

申请号：US12631574

申请日：2009-12-04

Applicant: Abraham McAllister ,  Malcolm Smith ,  Kostas Zafiriou ,  David Day ,  Michael Butler

Inventor： Abraham McAllister ,  Malcolm Smith ,  Kostas Zafiriou ,  David Day ,  Michael Butler

IPC: G01J5/02

CPC classification number: G01J3/18 ,  G01J1/0228 ,  G01J3/02 ,  G01J3/0229 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/06 ,  G01J3/2846 ,  G01J3/32 ,  G01J2003/1213 ,  G01J2003/1286

Abstract: According to one aspect, an IR spectrometer includes a light source adapted to illuminate a sample, a grating adapted to spectrally disperse a light that has illuminated the sample, a MEMS array adapted to be electrostatically actuated by a controller to control a diffraction of the light, a detector configured to detect the light, and a power source adapted to supply power to the light source and to the MEMS array, wherein the controller is adapted to control the MEMS array so as to manage a power consumption of the IR spectrometer. In one embodiment, the IR spectrometer includes a housing sized and arranged to house the light source, the grating, the MEMS array, the controller, the detector, to and the power source in a hand-held device.

Abstract translation: 根据一个方面，一种IR光谱仪包括适于照射样品的光源，适于光谱分散已经照射样品的光的光栅;适于由控制器静电致动以控制光的衍射的MEMS阵列 ，被配置为检测光的检测器，以及适于向所述光源和所述MEMS阵列供电的电源，其中所述控制器适于控制所述MEMS阵列以便管理所述IR光谱仪的功率消耗。 在一个实施例中，IR光谱仪包括尺寸和布置成在手持式装置中容纳光源，光栅，MEMS阵列，控制器，检测器和电源的外壳。