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    탈모방지 및 발모촉진용 외용제 조성물
    13.
    发明公开
    탈모방지 및 발모촉진용 외용제 조성물 无效
    外用组合物，用于抑制头发损失和增加头发生长

    公开(公告)号：KR1020080027526A

    公开(公告)日：2008-03-28

    申请号：KR1020060092676

    申请日：2006-09-25

    Applicant: (주)아모레퍼시픽

    Inventor： 박원석 ,  성대석 ,  박종희 ,  한지숙 ,  이창훈 ,  황재성 ,  장이섭

    IPC: A61K31/506 ,  A61K31/19 ,  A61P17/14

    CPC classification number: A61K8/4953 ,  A61K8/34 ,  A61K8/92 ,  A61Q7/00 ,  Y10S514/88 ,  Y10S514/969

    Abstract: A composition comprising minoxidil, tretinoin(all-trans retinoic acid), a solvent and glycerine is provided to promote permeation of the minoxidil without stimulus of the tretinoin, thereby inducing hair growth and alleviating alopecia. An external composition for preventing hair loss and promoting hair growth comprises 0.5-7.5 weight/volume% of minoxidil as a hair growth ingredient, 0.007-0.015 weight/volume% of tretinoin, 72-83 weight/volume% of ethanol, and 15-20 weight/volume% of glycerine.

    Abstract translation: 提供包含米诺地尔，维A酸（全反式视黄酸），溶剂和甘油的组合物，以促进米诺地尔的渗透，而不刺激维甲酸，从而诱导毛发生长和减轻脱发。 用于防止脱发和促进毛发生长的外用组合物包含0.5-7.5重量/体积％的作为毛发生长成分的米诺地尔，0.007-0.015重量/体积％的维甲酸，72-83重量/体积％的乙醇和15- 20重量/体积％的甘油。

    생약 추출물을 함유하는 가려움증 억제 및 완화용 조성물
    14.
    发明公开
    생약 추출물을 함유하는 가려움증 억제 및 완화용 조성물 有权
    组合物包含原发性药物提取物显示抗病毒作用

    公开(公告)号：KR1020070107961A

    公开(公告)日：2007-11-08

    申请号：KR1020060040588

    申请日：2006-05-04

    Applicant: (주)아모레퍼시픽

    Inventor： 김대권 ,  성대석 ,  김광미 ,  김형준 ,  한지숙 ,  김혁 ,  성기사 ,  박종희 ,  조선아 ,  이창훈 ,  김정주

    IPC: A61K36/9068 ,  A61K36/754

    CPC classification number: A61K36/00 ,  A61K8/97 ,  A61K9/00 ,  A61K36/754 ,  A61K36/9062 ,  A61K36/9068 ,  A61K2236/33 ,  A61Q19/00 ,  A61Q19/005 ,  Y10S514/857

    Abstract: A composition comprising extracts of crude drugs is provided to suppress and relieve itching caused by inflammatory and atopic dermatitis without side effects such as toxicity and skin irritation. A composition for suppressing and relieving itching comprises 0.1-10 wt.% of the extracts of Zingiber officinale Rosc., Evodia officinalis and Alpinia katsumadai Hayata which are prepared by extracting them with water, C1-C4 lower alcohol or a mixed solvent thereof. The daily dosage of crude drug extracts is 0.001-100 mg/kg, preferably 0.1-30 mg/kg and the composition is a pharmaceutical composition having a formulation selected from ointment, plaster, lotion and liniment, or a cosmetic composition having a formulation selected from skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutrition lotion, massage cream, nutrition cream, moisture cream, hand cream, foundation, essence, nutrition essence, pack, soap, cleansing foam, cleansing lotion, cleansing cream, body lotion and body cleanser.

    Abstract translation: 提供包含生药提取物的组合物以抑制和缓解由炎性和特应性皮炎引起的瘙痒，而没有副作用，例如毒性和皮肤刺激。 用于抑制和缓解瘙痒的组合物包括通过用水，C1-C4低级醇或其混合溶剂提取它们制备的姜黄提取物的0.1-10重量％的提取物。 生药提取物的日剂量为0.001-100mg / kg，优选0.1-30mg / kg，并且组合物是具有选自软膏，石膏，洗剂和搽剂的制剂的药物组合物或具有选择的制剂的化妆品组合物 从皮肤洗剂，皮肤柔肤剂，皮肤调色剂，收敛剂，乳液，乳液，滋润乳液，营养乳液，按摩霜，营养霜，保湿霜，护手霜，粉底，精华，营养精华，包装，肥皂，清洁泡沫，清洁 洗剂，清洁霜，身体乳液和身体清洁剂。

    2,2-디메틸-3-알킬에테르-4-알콕시-6-알킬 아미노벤조피란 유도체를 유효성분으로 함유하는 PGE2 활성에 관련된 염증질환 치료제
    15.
    发明公开
    2,2-디메틸-3-알킬에테르-4-알콕시-6-알킬 아미노벤조피란 유도체를 유효성분으로 함유하는 PGE2 활성에 관련된 염증질환 치료제 有权
    含有2,2-二甲基-3-烷基-4-烷氧基-6-烷基氨基苯甲酰基衍生物的2,2-二甲基-3-烷基-4-烷氧基-6-烷基氨基苯并噻吩衍生物和PGE2生产抑制剂作为有效成分

    公开(公告)号：KR1020060123000A

    公开(公告)日：2006-12-01

    申请号：KR1020050045294

    申请日：2005-05-28

    Applicant: 한국화학연구원 ,  (주)아모레퍼시픽

    Inventor： 공영대 ,  이일영 ,  이종철 ,  조희영 ,  황종연 ,  최형섭 ,  전현숙 ,  유성은 ,  이창훈 ,  성대석 ,  김광미 ,  김대권 ,  양혜진 ,  김형준 ,  박종희 ,  심영철

    IPC: C07D311/22 ,  C07D311/24

    CPC classification number: C07D311/22

    Abstract: 2,2-Dimethyl-3-alkylether-4-alkoxy-6-alkyl amino benzopyrane derivatives and PGE2(prostagrandine E2) production inhibitors containing the same compounds as an effective ingredient are provided to treat diseases associated with the activity of PGE2 by suppressing inflammation caused by PGE2. The 2,2-dimethyl-3-alkylether-4-alkoxy-6-alkyl amino benzopyrane derivatives represented by the formula(1) or their pharmaceutically acceptable salts are provided, wherein R^1 and R^2 are identical or different, and are each independently C1-C10 linear, branched or cyclic alkyl group, optionally substituted benzyl group or penethyl group; and R^3 is hydrogen, C1-C10 alkyl group, C2-C10 alkenyl group, C2-C10 alkynyl group, optionally substituted benzyl group or naphthylmethyl group. The PGE2 production inhibitors contain 2,2-dimethyl-3-alkylether-4-alkoxy-6-alkyl amino benzopyrane derivatives represented by the formula(1) or their pharmaceutically acceptable salts as effective ingredient.

    Abstract translation: 提供含有相同化合物作为有效成分的2,2-二甲基-3-烷基醚-4-烷氧基-6-烷基氨基苯并吡喃衍生物和PGE2（前列腺素E2）产生抑制剂，用于通过抑制炎症来治疗与PGE2的活性相关的疾病 由PGE2引起。 提供由式（1）表示的2,2-二甲基-3-烷基醚-4-烷氧基-6-烷基氨基苯并吡喃衍生物或其药学上可接受的盐，其中R 1和R 2相同或不同，和 各自独立地为C 1 -C 10直链，支链或环状烷基，任选取代的苄基或苯乙基; R 3为氢，C 1 -C 10烷基，C 2〜C 10烯基，C 2〜C 10炔基，任意取代的苄基或萘甲基。 PGE 2生成抑制剂含有式（1）表示的2,2-二甲基-3-烷基醚-4-烷氧基-6-烷基氨基苯并吡喃衍生物或其药学上可接受的盐作为有效成分。

    헥사미딘류 및 레티노이드류를 함유하는 피부 개선 조성물
    20.
    发明公开
    헥사미딘류 및 레티노이드류를 함유하는 피부 개선 조성물 有权
    包含一类类别的异黄酮和一类用于改善皮肤状况的再生剂的组合物

    公开(公告)号：KR1020110019571A

    公开(公告)日：2011-02-28

    申请号：KR1020090077158

    申请日：2009-08-20

    Applicant: (주)아모레퍼시픽

    Inventor： 박종희 ,  박신영 ,  신홍주 ,  김도훈 ,  이창근 ,  박원석 ,  고현주 ,  김정환 ,  김형준

    IPC: A61K31/155 ,  A61P17/10 ,  A61P17/08 ,  A61K31/203

    CPC classification number: A61K31/155 ,  A61K31/203

    Abstract: PURPOSE: A composition containing hexamidine and retinoid is provided to prevent skin pigmentation and control sebum and pore. CONSTITUTION: A compositioin contains 0.0001-15 weight% of hexamidine, derivative thereof, or pharmaceutically acceptable salt thereof; and 0.0001-15 weight% of retinoid, derivative thereof, or pharmaceutically acceptable salt thereof as an active ingredient. The composition is used for controlling sebum and pore and preventing skin pigmentation. The composition further contains 0.001-10 weight% of ceramide.

    Abstract translation: 目的：提供含有己脒和类视色素的组合物，以防止皮肤色素沉淀和控制皮脂和毛孔。 组成：组合物含有0.0001-15重量％的己脒，其衍生物或其药学上可接受的盐; 和0.0001-15重量％的类视黄醇，其衍生物或其药学上可接受的盐作为活性成分。 该组合物用于控制皮脂和毛孔并防止皮肤色素沉着。 组合物还含有0.001-10重量％的神经酰胺。

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