公开(公告)号：KR1020120021397A

公开(公告)日：2012-03-09

申请号：KR1020100073498

申请日：2010-07-29

Applicant: 강원대학교산학협력단

Inventor： 이현용 ,  정향숙 ,  김승섭 ,  오성호 ,  정명훈 ,  최운용 ,  서용창 ,  김지선 ,  황보영 ,  나천수

IPC: A61K47/38 ,  A61K36/73 ,  A61K9/16 ,  A61P35/00

CPC classification number: A61K47/38 ,  A61K9/16 ,  A61K36/73 ,  A61K2236/331 ,  Y10S514/885

Abstract: PURPOSE: A method for making Rubus coreanus Miquel nanoparticles using water soluble cellulose is provided to enhance colon cell immunite and anticancer activity. CONSTITUTION: A method for making Rubus coreanus Miquel nanoparticles for enhancing immunity and anti-cancer activity using hydroxypropyl cellulose comprises: a step of extracting Rubus coreanus Miquel at 60°C for 24 hours and filtering and freeze-drying to prepare powder; a step of dissolving the powder in 1mg/ml of distilled water; a step of mixing with 0.05 wt% of tween 80 on a container on which bottom is coated with hydroxypropyl cellulose; and a step of passing the mixture through a nano disperser at 2 ml/min for 10 minutes.

Abstract translation: 目的：提供使用水溶性纤维素制备Rubus coreanus Miquel纳米颗粒的方法，以增强结肠细胞免疫和抗癌活性。 构成：使用羟丙基纤维素来增强免疫力和抗癌活性的Rubus coreanus Miquel纳米颗粒的方法包括：在60℃下提取Rubus coreanus Miquel 24小时并过滤并冷冻干燥以制备粉末的步骤; 将粉末溶解在1mg / ml蒸馏水中的步骤; 在底部涂有羟丙基纤维素的容器上与0.05重量％的吐温80混合的步骤; 以及将混合物通过纳米分散器以2ml / min进行10分钟的步骤。

公开(公告)号：KR1020100124413A

公开(公告)日：2010-11-29

申请号：KR1020090043391

申请日：2009-05-19

Applicant: 강원대학교산학협력단

Inventor： 이현용 ,  정향숙 ,  한재건 ,  하지혜 ,  정명훈 ,  김승섭 ,  오성호 ,  김영 ,  곽형근 ,  황보영 ,  나천수

IPC: A61K8/97 ,  A61Q19/10 ,  A61K8/02

Abstract: PURPOSE: A method for manufacturing a cleansing composition by alginate nano granulation of Angelica gigas nakai is provided to obtain an active substance without damage. CONSTITUTION: A method for manufacturing cleansing composition by alginate nano granulation of Angelica gigas nakai comprises: a step of pulverizing Angelica gigas nakai; a step of extracting pulverized Angelica gigas nakai in 10 times volume of distilled water at 60°C for 24 hours; a step of filtering/concentrating the hot water extract and freeze-drying to obtain powder; a step of dissolving the powder in 1mg/ml of distilled water; a step of dissolving alginate in distilled water and evaporating distilled water to form multilayer; a step of adding liquid phase Angelica gigas nakai extract sample and homogenizing by sonication.

Abstract translation: 目的：提供当归粉末的藻酸盐纳米颗粒制造清洁组合物的方法，以获得活性物质而不损坏。 构成：当归黑藻的藻酸盐纳米颗粒制造清洁组合物的方法包括：将当归粉末粉碎的步骤; 在10℃下将10倍体积的蒸馏水中的当归提取粉末状的步骤在60℃下提取24小时; 过滤/浓缩热水提取物并冷冻干燥以获得粉末的步骤; 将粉末溶解在1mg / ml蒸馏水中的步骤; 将藻酸盐溶解在蒸馏水中并蒸发蒸馏水形成多层的步骤; 加入液相当归黑加提取物样品并通过超声处理均质化的步骤。