Abstract:
본 발명은 벌개미취( Aster koraiensis ) 추출물, 벌개미취 분획물, 이로부터 분리한 짐나스테르코리아인(Gymnasterkoreaynes) 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 발암 예방용 건강기능성 식품 조성물에 관한 것으로서, 특히 벌개미취 추출물로부터 분리한 단일화합물인 짐나스테르코리아인 B는 암 예방 지표효소인 퀴논 리덕타제(Quinone reductase)의 활성을 유도하므로, 본 발명에 따른 조성물은 암을 예방하는데 유용하게 사용될 수 있다.
Abstract:
Provided are a method for producing a compound having decreased sugar of a glycoside compound, and an extract, a pharmaceutical composition, and a food composition including a compound having reduced or removed sugar of the glycoside compound. And more specifically, provided is a method for producing a compound having decreased or removed sugar of the glycoside compound comprising a step of microwave-irradiating a glycoside compound including O-glycoside combination.
Abstract:
본 발명은 녹는점 이상으로 가열하여 녹였다가 녹는점 미만으로 식힌 강황 추출물 (tumeric extract) 또는 커큐민, 이들을 포함하는 조성물 및 제조방법에 대한 것이다. 녹인 후 식힌 강황 추출물 또는 커큐민은 무정형 (amorphous)을 이루며 결정성인 녹이지 않은 강황 추출물 또는 커큐민에 비해 생체적합성 용매인에 높은 용해도를 가진다.
Abstract:
Provided is a composition containing arylnaphthalene lignan derivatives, that are one or more selected from a group consisting of Justicidin A, 5-methoxyjusticidin A, Chinensinaphtol, and a pharmaceutically acceptable salt thereof as an active ingredient for preventing, relieving, and/or treating dementia, and ameliorating memory impairment and/or improving memory.
Abstract:
PURPOSE: A biocompatible polymer delivery system for drug delivery with the surface modified by glycol chitosan and heparin is provided to enhance blood retention and circulation and to effectively deliver a drug to a target site of cancer tissue. CONSTITUTION: A method for preparing biocompatible polymer nano delivery system comprises: a step of mixing and dissolving polyoxyethylene sorbitan monooleate(Tween80) of chemical formula 1 with drug; a step of adding lecithin lipid of chemical formula 2 to the mixture and mixing; a step of impregnating the secondary mixture to a triblock copolymer solution of chemical formula 3(HO(C_2H_4O)_a(C_3H_6O)_b(C_2H_4O)_cH) to prepare a nano delivery system; and a step of adding glycol chitosan of chemical formula 4 and heparin solution of chemical formula 5 to the nano delivery system to modifier the surface of the nano delivery system.
Abstract translation:目的:提供用于药物递送的生物相容性聚合物递送系统,其由乙二醇壳聚糖和肝素修饰,以增强血液保持和循环,并有效地将药物递送至癌组织的靶位点。 构成:制备生物相容性聚合物纳米递送系统的方法包括:将化学式1的聚氧乙烯山梨糖醇酐单油酸酯(吐温80)与药物混合并溶解的步骤; 将化学式2的卵磷脂脂加入混合物中并混匀; 将二次混合物浸渍到化学式3(HO(C 2 H 4 O)_a(C 3 H 6 O)_b(C 2 H 4 O)_cH)的三嵌段共聚物溶液中以制备纳米递送系统; 将化学式4的乙二醇壳聚糖和化学式5的肝素溶液加入到纳米递送系统中以改性纳米递送系统的表面的步骤。