公开(公告)号：JPS62207268A

公开(公告)日：1987-09-11

申请号：JP4936686

申请日：1986-03-06

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  YANAGIYA KOSHIN ,  SHIBUYA ISAO ,  SUHARA YASUO

IPC: C07D339/06

Abstract: PURPOSE:To obtain the titled compound useful as an intermediate for tetrathiafulvalene (electric charge transfer complex) or an intermediate substance for physiological active substance simply and in high yield, by reacting thiirane compound with carbon disulfide in the presence of a base at a high temperature. CONSTITUTION:A thiirane compound shown by formula I (R is alkyl or aryl; R and R are alkyl or H) is reacted with carbon disulfide in the presence of a base such as tertiary amine, e.g. triethylamine, pyridine, etc. at high pressure of 500-9,000kg/cm at room temperature -100 deg.C to give the aimed compound shown by formula II in high yield and efficiently. The compound shown by formula I can be readily synthesized from a corresponding epoxide and thiourea or potassium thiocyanate and carbon dioxide is inexpensively sold on the market.

公开(公告)号：JPS6219582A

公开(公告)日：1987-01-28

申请号：JP15952585

申请日：1985-07-19

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  SUHARA YASUO

IPC: C07D333/32 ,  C07D333/38 ,  C07D333/68

Abstract: PURPOSE:To obtain simply in high yield a compound useful as a germicide, an anti-inflammatory agent, an activator for polymerization, etc., by reacting thiirane with an active methylene compound in the presence of a strong base. CONSTITUTION:A thiirane shown by the formula I (R is alkyl, aryl, or H; R and R are alkyl or H) is reacted with an active methylene compound shown by the formula II (R is alkyl; R is alkyl or alkoxy) in the presence of a base (e.g., sodium ethoxide) in a solution of an alkali catalyst (e.g., sodium hydride) in a solvent such as ethanol, etc., at room temperature or under heating to give the aimed compound shown by the formula III or formula IV. The compound shown by the formula I is easily synthesized from a corresponding epoxide by the use of thiourea or potassium thiocyanate and the compound shown by the formula II is inexpensively on the market and easily obtainable.

公开(公告)号：JP2000281764A

公开(公告)日：2000-10-10

申请号：JP9339799

申请日：1999-03-31

Applicant: AGENCY IND SCIENCE TECHN

Inventor： OISHI AKIHIRO ,  TAGUCHI YOICHI ,  FUJITA KENICHI ,  IKEDA YOSHIKAZU ,  MASUDA TAKASHI ,  ISHIGAMI YUTAKA ,  NAKAYAMA KAZUO ,  KINUGASA SHINICHI ,  NAKAHARA HISAE

IPC: C08G63/08 ,  C08G63/78 ,  C08G63/82 ,  C08L101/16

Abstract: PROBLEM TO BE SOLVED: To provide a process for preparing a polymer polyester or polyester copolymer from a cyclic lactone through ring-opening polymerization. SOLUTION: In a preparation process of a polymer polyester, a cyclic lactone of the formula (wherein, (n) is 1, 3 or 4) is allowed to react under a high- pressure condition of at least 200 MPa without using a catalyst. Alternatively, in the absence of catalysts or in the presence of a non-metal esterification catalyst, a lactone mixture comprising two or more cyclic lactones of the formula is allowed to react under a high-pressure condition of at least 200 MPa.

公开(公告)号：JPH03258768A

公开(公告)日：1991-11-19

申请号：JP5577990

申请日：1990-03-07

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  SHIBUYA ISAO

IPC: C07D251/38 ,  A01N43/64

Abstract: PURPOSE:To simply prepare a 1,3,5-perhydrotriazine-2,4,6-trithione derivative in a high yield by reacting an isothiocyanic acid ester in the presence of a base under a high pressure. CONSTITUTION:An isothiocyanic acid ester of formula RNCS (R is alkyl, aryl) is reacted with in the presence of a base such as triethylamine in a solvent such as benzene at room temperature to 100 deg.C under a high pressure of 500-9000kg/cm to provide the objective compound. 1,3,5-Trimethyl-1,3,5- perhydrotrithione is active to diseases of rice and an oxygen homologue thereof, an isocyanuric acid derivative, is useful as a modifying agent for resins, etc.

公开(公告)号：JPS63218672A

公开(公告)日：1988-09-12

申请号：JP5274887

申请日：1987-03-07

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  YANAGIYA KOSHIN ,  SHIBUYA ISAO ,  SUHARA YASUO

IPC: C07D327/04 ,  B01J31/02 ,  C07B61/00 ,  C07D339/06

Abstract: PURPOSE:To obtain the titled substance useful as a synthetic intermediate for tetrathiafulvalene which is a charge-transfer complex, intermediate material for physiologically active substance or the like in one stage and good yield, by reacting an epoxide with CS2 in the presence of a base under high pressure. CONSTITUTION:An epoxide expressed by formula I (R is alkyl or aryl; R and R are alkyl or H) is reacted with CS2 in the presence of a base (preferably tert. amine) at high pressure of 500-9,000kg/cm2 and room temperature - 120 deg.C for 5-50hr to provide the aimed compounds expressed by formula II and formula III.

公开(公告)号：JP2000256418A

公开(公告)日：2000-09-19

申请号：JP5982599

申请日：1999-03-08

Applicant: AGENCY IND SCIENCE TECHN

Inventor： FUJITA KENICHI ,  TAGUCHI YOICHI ,  OISHI AKIHIRO ,  IKEDA YOSHIKAZU

IPC: C07B61/00 ,  C08F8/30 ,  C08F12/14

Abstract: PROBLEM TO BE SOLVED: To obtain a novel polystyrene-supported chalcogenocyanate which consists of a polystyrene containing styrene units having a chalcogenocyanate group and is useful as a reaction reagent. SOLUTION: This polystyrene-supported chalcogenocyanate has units of formula I. It is obtained by reacting a potassium chalcogenocyanate and a polystyrene containing units of formula II in a solvent. In the formulas, R1 is a bivalent hydrocarbon; R2 is a bivalent aliphatic group; Ar is an arylene; Z is a bivalent coupling group consisting of a hetero atom or carbonyl; X is a chalcogen atom; Y is a halogen; and s, t, and n are each 0 or 1. Preferably, the polystyrene containing styrene units of formula II is in the form of spherical beads of 400-200 μm (100-400 mesh). A corresponding nucleophilic chalcogen reagent is obtained by reacting a reducing agent such as lithium borohydride or the like in a solvent such as tetrahydrofuran or the like.

公开(公告)号：JPH0899955A

公开(公告)日：1996-04-16

申请号：JP23730194

申请日：1994-09-30

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  OISHI AKIHIRO ,  SHIBUYA ISAO ,  TSUCHIYA TORU

IPC: C07D201/02 ,  C07D205/08

Abstract: PURPOSE: To easily and efficiently obtain the subject derivative useful as a synthetic intermediate for β-amino acid derivatives or antibiotics having penicillin-simulated structure, by reaction between an isocyanate and a vinyl ether compound. CONSTITUTION: This β-lactam derivative of the formula is obtained by reacting (A) an isocyanate of formula, R NCO (R is a hydrocarbon) (e.g. methyl isocyanate, cyclopentyl isocyanate, phenyl isocyanate) with (B) a vinyl ether compound of formula, CH2 =CH-O-R (R is a hydrocarbon) (pref. methyl vinyl ether, ethyl vinyl ether, cyclopentyl vinyl ether etc.) under a pressure of pref. >=2000atm (more pref. 2000-12000atm) at 20-130 deg.C.

公开(公告)号：JPH06263744A

公开(公告)日：1994-09-20

申请号：JP7891193

申请日：1993-03-12

Applicant: AGENCY IND SCIENCE TECHN

Inventor： OISHI AKIHIRO ,  YASUMOTO MASAHIKO ,  GOTO MIDORI ,  TSUCHIYA TORU ,  SHIBUYA ISAO ,  TAGUCHI YOICHI

IPC: C07D239/95

Abstract: PURPOSE:To obtain the subject compound useful as a physiologically active substance, etc., from inexpensive raw materials direct and in high yield by reacting a phenyl isothiocyanate with an N,N-di-substituted cyanamide under high pressure. CONSTITUTION:A compound of formula I (R is alkyl, cycloalkyl, acryl, alkoxy, etc.; (n) is 0-4; with the proviso that at leas one ortho position based on isothiocyanate group of benzene ring has H) is reacted with a compound of formula II (R and R are alkyl, cycloalkyl, aryl, arylalkyl, alkoxy, etc.; R together R may form a ring) under 500-20,000 atmospheric pressure at 30-20 deg.C preferably in the absence of a solvent. Optionally, the reactional product is treated with an acid to give the objective compound of formula III (HX is inorganic acid or organic acid; (m) is 0 or 1).

公开(公告)号：JPH05310730A

公开(公告)日：1993-11-22

申请号：JP11396292

申请日：1992-04-07

Applicant: AGENCY IND SCIENCE TECHN

Inventor： SHIBUYA ISAO ,  YONEMOTO KATSUMI ,  YASUMOTO MASAHIKO ,  TAGUCHI YOICHI ,  TSUCHIYA TORU ,  MIZUNO MASAKI

IPC: B01J27/12 ,  B01J27/06 ,  B01J27/25 ,  B01J31/02 ,  B01J31/04 ,  B01J31/26 ,  C07B61/00 ,  C07D339/06

Abstract: PURPOSE:To easily and directly obtain a 2-(disubstituted methylens)-1,3-dithiol in an economically advantageous way from a 1,3-dithiol-2-thione compound. CONSTITUTION:The compound of formula II can advantageously be obtained by reaction of (A) a compound of formula I (R and R are each H or inert substituent, or may form a ring through mutual binding of their terminals) with (B) a compound of formula R -CH2-R (R and R are each electron- accepting group) in the presence of (C) a silver salt, e.g. an organic carboxylic acid silver salt such as silver benzoate or silver acetate, or an inorganic silver salt such as silver nitrate, silver tetrafluoroborate or silver perchlorate, esp. a fluorine-contg. organic carboxylic acid silver salt such as CF3COOAg and (D) a base, pref. a tertiary amine, pref. in an anhydrous solvent at 0-150 (pref. room temperature to 80) deg.C. The amounts of the components to be used are as follows: B=1-2mol, C=1-5mol (each per mol of A); D=2-10mol per mol of B.

公开(公告)号：JPH04210672A

公开(公告)日：1992-07-31

申请号：JP34105290

申请日：1990-11-30

Applicant: AGENCY IND SCIENCE TECHN

Inventor： SHIBUYA ISAO ,  YONEMOTO KATSUMI ,  TSUCHIYA TORU ,  YASUMOTO MASAHIKO ,  TAGUCHI YOICHI

IPC: C07C333/02 ,  C07C333/04 ,  C07C333/08

Abstract: NEW MATERIAL:An N-aroyl-S-(di-substituted carbamoyl)sulfenamide expressed by formula I (R is di-substituted amino; R is aryl). EXAMPLE:N-Benzoyl-S-(dimethylcarbamoyl) sulfenamide. USE:An anti-fogging agent in silver halide photograph. The compound expressed by formula I has complex forming ability also to various kind of metal ions other than silver and is useful also as a chelate agent and extracting reagent. PREPARATION:N-aroyl-S-substituted thiocarbonylsulfenamides expressed by formula II are reacted with metal salts (e.g. silver, copper (I), mercury or lead (II)) in the presence of an acid and water in a solvent (e.g. chloroform) at ambient temperature to heated temperature to provide the compound expressed by formula I.