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公开(公告)号:NZ283333A
公开(公告)日:1997-02-24
申请号:NZ28333395
申请日:1995-03-23
Applicant: BASF AG
Inventor: BAUMANN ERNST , VOGELBACHER UWE JOSEF , RHEINHEIMER JOACHIM , KLINGE DAGMAR , RIECHERS HARTMUT , KROGER BURKHARD , BIALOJAN SIEGFRIED , BOLLSCHWEILER CLAUS , WERNET WOLFGANG , UNGER LILIANE , RASCHACK MANFRED
IPC: A61K31/00 , A61K31/505 , A61K31/506 , A61K31/53 , C07D251/26 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P25/04 , A61P39/02 , C07D239/26 , C07D239/34 , C07D239/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D239/00 , C07D251/00
Abstract: PCT No. PCT/EP95/01099 Sec. 371 Date Sep. 30, 1996 Sec. 102(e) Date Sep. 30, 1996 PCT Filed Mar. 23, 1995 PCT Pub. No. WO95/26716 PCT Pub. Date Oct. 12, 1995A method of inhibiting endothelin receptors by administering to a patient a compound of the formula I I
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公开(公告)号:AT146526T
公开(公告)日:1997-01-15
申请号:AT92919916
申请日:1992-09-21
Applicant: BASF AG
Inventor: FRIEDRICH THOMAS , BIALOJAN SIEGFRIED , BOLLSCHWEILER CLAUS , KUENAST CHRISTOPH
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公开(公告)号:NO970161D0
公开(公告)日:1997-01-14
申请号:NO970161
申请日:1997-01-14
Applicant: BASF AG
Inventor: HELLENDAHL BEATE , LANSKY ANNEGRET , MUNSCHAUER RAINER , BIALOJAN SIEGFRIED , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , WICKE KARSTEN , DRESCHER KARLA
IPC: C07D249/08 , A61K31/41 , A61K31/435 , A61K31/4427 , A61K31/445 , A61K31/505 , A61K31/53 , A61P1/08 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , C07D249/12 , C07D249/14 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14
Abstract: PCT No. PCT/EP95/02781 Sec. 371 Date Jan. 14, 1997 Sec. 102(e) Date Jan. 14, 1997 PCT Filed Jul. 14, 1995 PCT Pub. No. WO96/02520 PCT Pub. Date Feb. 1, 1996The present invention relates to triazole compounds of the following formula: where R1, R2, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.
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公开(公告)号:NO964121A
公开(公告)日:1996-11-26
申请号:NO964121
申请日:1996-09-27
Applicant: BASF AG
Inventor: BAUMANN ERNST , VOGELBACHER UWE JOSEF , RHEINHEIMER JOACHIM , KLINGE DAGMAR , RIECHERS HARTMUT , KROGER BURKHARD , BIALOJAN SIEGFRIED , BOLLSCHWEILER CLAUS , WERNET WOLFGANG , UNGER LILIANE , RASCHACK MANFRED
IPC: C07D251/26 , A61K31/505 , A61K31/506 , A61K31/53 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P25/04 , A61P39/02 , C07D239/26 , C07D239/34 , C07D239/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , A61K
CPC classification number: A61K31/505 , A61K31/506 , A61K31/53
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公开(公告)号:FI963885A0
公开(公告)日:1996-09-27
申请号:FI963885
申请日:1996-09-27
Applicant: BASF AG
Inventor: BAUMANN ERNST , VOGELBACHER UWE JOSEF , RHEINHEIMER JOACHIM , KLINGE DAGMAR , RIECHERS HARTMUT , KROEGER BURKHARD , BIALOJAN SIEGFRIED , BOLLSCHWEILER CLAUS , WERNET WOLFGANG , UNGER LILIANE , RASCHACK MANFRED
IPC: C07D251/26 , A61K31/00 , A61K31/505 , A61K31/506 , A61K31/53 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P25/04 , A61P39/02 , C07D239/26 , C07D239/34 , C07D239/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , A61K
Abstract: PCT No. PCT/EP95/01099 Sec. 371 Date Sep. 30, 1996 Sec. 102(e) Date Sep. 30, 1996 PCT Filed Mar. 23, 1995 PCT Pub. No. WO95/26716 PCT Pub. Date Oct. 12, 1995A method of inhibiting endothelin receptors by administering to a patient a compound of the formula I I
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公开(公告)号:AT130872T
公开(公告)日:1995-12-15
申请号:AT91912909
申请日:1991-07-19
Applicant: BASF AG
Inventor: BACH ALFRED , HILLEN HEINZ , BIALOJAN SIEGFRIED
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公开(公告)号:CA2121352A1
公开(公告)日:1993-05-13
申请号:CA2121352
申请日:1992-10-27
Applicant: BASF AG
Inventor: FRIEDRICH THOMAS , BIALOJAN SIEGFRIED , KROEGER BURKHARD , KUENAST CHRISTOPH
IPC: A61K35/64 , A61K38/00 , A61K38/55 , A61P7/02 , C07K14/00 , C07K14/245 , C07K14/435 , C07K14/81 , C12N15/15 , C12P21/02 , C12R1/19 , A61K38/57
Abstract: 2121352 9309232 PCTABS00022 The description relates to a novel thrombin inhibiting protein from reduvii with a molecular weight of some 12000 Dalton and the N-terminus Glu-Gly-Gly-Glu-Pro-Cys-Ala-Cys-Pro-His-Ala-Leu-His-Arg-Val-Cys-Gly-Ser-Asp. The protein is useful in combatting diseases.
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公开(公告)号:CA2121246A1
公开(公告)日:1993-05-13
申请号:CA2121246
申请日:1992-09-23
Applicant: BASF AG
Inventor: FRIEDRICH THOMAS , KOERWER WOLFGANG , KROEGER BURKHARD , BIALOJAN SIEGFRIED
IPC: A61K35/64 , A61K38/00 , A61K38/55 , A61P7/02 , C07K1/14 , C07K14/435 , C07K14/81 , C12N15/09 , C12N15/15 , C12P21/02 , A61K38/57
Abstract: 2121246 9309231 PCTABS00022 The invention relates to a novel thrombin-inhibiting protein from ticks with a molecular weight of some 26000 Dalton and which has the amino acid partial sequences Val-Ala-Lys-Phe-Ala-X-Asn-Ser-Gly-Ser-Glu-Thr-Gly, His-Ala-Y-Phe-Glu, Arg-Val-Ser-Asp-Phe-Glu and Phe-Val-Tyr-Thr-Ile-Glu, in which X and Y may be the same or different and stand for a naturally occurring amino acid. The protein is suitable for combatting diseases.
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公开(公告)号:MX9206339A
公开(公告)日:1993-05-01
申请号:MX9206339
申请日:1992-11-04
Applicant: BASF AG
Inventor: FRIEDRICH THOMAS , BIALOJAN SIEGFRIED , KROEGER BURKHARD , KUENAST CHRISTIPH
IPC: A61K35/64 , A61K38/00 , A61K38/55 , A61P7/02 , C07K14/00 , C07K14/245 , C07K14/435 , C07K14/81 , C12N15/15 , C12P21/02 , C12R1/19
Abstract: PCT No. PCT/EP92/02450 Sec. 371 Date Apr. 26, 1994 Sec. 102(e) Date Apr. 26, 1994 PCT Filed Oct. 27, 1992 PCT Pub. No. WO93/09232 PCT Pub. Date May 13, 1993.A novel thrombin-inhibitory protein from assassin bugs with a molecular weight of about 12,000 dalton and the N terminus Glu-Gly-Gly-Glu-Pro-Cys-Ala-Cys-Pro-His-Ala-Leu-His-Arg-Val-Cys-Gly-Ser-Asp is described. The protein is suitable for controlling diseases.
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公开(公告)号:CA2186784C
公开(公告)日:2007-02-20
申请号:CA2186784
申请日:1995-03-23
Applicant: BASF AG
Inventor: BAUMANN ERNST , VOGELBACHER UWE JOSEF , RHEINHEIMER JOACHIM , KLINGE DAGMAR , RIECHERS HARTMUT , KROGER BURKHARD , BIALOJAN SIEGFRIED , WERNET WOLFGANG , UNGER LILIANE , RASCHACK MANFRED , BOLLSCHWEILER CLAUS
IPC: A61K31/505 , C07D251/26 , A61K31/00 , A61K31/19 , A61K31/215 , A61K31/506 , A61K31/53 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P25/04 , A61P39/02 , C07D239/26 , C07D239/34 , C07D239/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12
Abstract: The invention concerns the use of carboxylic acid derivatives of formula I ( I) in which R means a formyl group, a CO2H group or a residue which can be hydrolysed to form COOH; X means nitrogen or CR14, wherein R14 means hydroge n or, together with R3, forms a 3- to 4-member alkylene or alkenylene chain in each of which a methyl group can be replaced by oxygen; Y means sulphur or oxygen or a single bond; Z means sulphur or oxygen; and the other substituen ts have the meanings given in the description. These derivatives can be used fo r preparing medicaments.
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