公开(公告)号：CA2332270A1

公开(公告)日：1999-11-25

申请号：CA2332270

申请日：1999-05-04

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  ZEIDLER JURGEN ,  BINDER RUDOLF ,  BREITENBACH JORG ,  PFLUGER PETER ,  AUWETER HELMUT ,  HEGER ROBERT

IPC: A61K9/16 ,  A61K9/51 ,  A61K38/00 ,  A61K38/13 ,  A61K47/14 ,  A61K47/36 ,  A61P37/06

Abstract: The invention relates to solid or liquid cyclosporin preparations for oral administration in which the cyclosporin is presented in the form of solid Xamorphous particles embedded in a coating matrix in a colloidally dispersed manner.

公开(公告)号：BR9711777A

公开(公告)日：1999-08-24

申请号：BR9711777

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：NZ298414A

公开(公告)日：1999-02-25

申请号：NZ29841495

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  GRABOWSKI SVEN ,  BREITENBACH JORG

IPC: A61J1/03 ,  A61J3/00 ,  A61J3/10 ,  A61K9/20 ,  A61K9/28 ,  B30B11/16 ,  B65B9/04

公开(公告)号：AU702198B2

公开(公告)日：1999-02-18

申请号：AU4434296

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  BREITENBACH JORG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05119 Sec. 371 Date Jun. 20, 1997 Sec. 102(e) Date Jun. 20, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19964 PCT Pub. Date Jul. 4, 1996The present invention relates to a process for the production of lenticular tablets by melt calendering in which molding rolls with depressions in the shape of segments of an ellipsoid are used. The process according to the invention affords tablets which are easily deflashed and in which the tablet residue to be abraded when there is a displacement between the upper and lower half of the tablet is small.

公开(公告)号：NZ302243A

公开(公告)日：1999-01-28

申请号：NZ30224396

申请日：1996-02-01

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  BREITENBACH JORG ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/22 ,  A61K9/20 ,  A61K47/48

Abstract: PCT No. PCT/EP96/00417 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/25151 PCT Pub. Date Aug. 22, 1996Solid preparations are obtainable by melt extrusion of A) at least one active compound, B) a mixture of B1) from 10 to 90% by weight of a water-soluble, thermoplastic polymer, and B2) from 10 to 90% by weight of a low-substituted hydroxypropylcellulose, and C) from 0 to 50% by weight, based on the total amount of the preparation, of customary pharmaceutical auxiliaries.

公开(公告)号：MX9704568A

公开(公告)日：1998-07-31

申请号：MX9704568

申请日：1997-06-19

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  GRABOWSKI SVEN ,  BREITENBACH JORG

IPC: A61J1/03 ,  A61J3/00 ,  A61J3/10 ,  A61K9/20 ,  A61K9/28 ,  B30B11/16 ,  B65B9/04 ,  A61J03/10 ,  A61K09/50 ,  B65B09/04

Abstract: La presente invencion se refiere a un proceso para la produccion de tabletas recubiertas mediante el calandrado de una masa fundida en el que la masa fundida que contiene el ingrediente activo se introduce entre dos hojas del material recubridor en los rodillos de moldeo.

公开(公告)号：AU4384697A

公开(公告)日：1998-04-02

申请号：AU4384697

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：AU2770097A

公开(公告)日：1997-11-26

申请号：AU2770097

申请日：1997-04-24

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  KOLTER KARL ,  SCHMITT ANGELIKA

IPC: C08J3/12 ,  A61K8/81 ,  A61K9/28 ,  A61K47/32 ,  A61Q1/12 ,  C08J3/03 ,  C08L31/00 ,  C08L33/08 ,  C08L33/10

Abstract: Polymer powders redispersible in aqueous solution, their use in cosmetic, pharmaceutical or crop protection formulations and a process for preparing polymer powders redispersible in aqueous solution comprising copolymers carrying free acid or base groups and, if appropriate, auxiliaries, which comprises adjusting the pH of the dispersion prior to drying by the addition of at least one buffer system to a pH of from 2.0 to 6.5 in the case of copolymers carrying free acid groups or a pH of from pH 7.5 to 12 in the case of copolymers carrying free base groups.

公开(公告)号：AU6875396A

公开(公告)日：1997-03-19

申请号：AU6875396

申请日：1996-08-21

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JORG

IPC: A61K9/20

Abstract: Lipids are used as aids in the production of solid drug forms by melt extrusion.

公开(公告)号：MX9602809A

公开(公告)日：1997-01-31

申请号：MX9602809

申请日：1996-07-17

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  SANNER AXEL ,  LANG SIEGFRIED ,  REICH HANS-BERND

IPC: A61L2/16 ,  A01N25/10 ,  A01N25/12 ,  A01N59/12 ,  A61K9/16 ,  A61K9/20 ,  A61K33/18 ,  A61K47/32 ,  A61P17/00

Abstract: Preparaciones adecuadas para desinfeccion que contienen un yodoforo que consiste de: a) 20 a 71% en peso de polivinilpirrolidona, poli-N-vinilcaprolactam o bien mezclas de los mismos. b) de 20 a 71% en peso de dextrina con un valor equivalente de dextrosa de 2 a 40, c) de 6 a 25% en peso de iodo elemental, y d) de 3 a 12.5% en peso de iones yoduro.