公开(公告)号：DE19617802A1

公开(公告)日：1997-11-06

申请号：DE19617802

申请日：1996-05-03

Applicant: BASF AG

Inventor： RUEHL THOMAS DR ,  PREISS THOMAS DR ,  HENKELMANN JOCHEM DR

IPC: B01J31/26 ,  C07B61/00 ,  C07C213/02 ,  C07C213/08 ,  C07C215/08 ,  C07C215/12 ,  C07C215/24 ,  C07C217/08 ,  C07C217/46 ,  C07C213/00 ,  C07D295/027

Abstract: Preparation of hydroxy-alkyl substd. amino-alkyne derivatives of formula R1-C IDENTICAL C-CR2R3-NR4R5 (I) is claimed in reaction by the heterogeneously catalysed reaction of an alkyne of formula R1-C IDENTICAL CH (II), a carbonyl compound of formula O=CR2R3 (III) and an amine of formula H-NR4R5 (IV). R1 = H, alkyl, haloalkyl, cycloalkyl, aryl, alkoxy, alkoxyalkyl or hydroxyalkyl; R2, R3 = H, alkyl, haloalkyl, aryl or alkoxy; R4, R5 = H, alkyl, haloalkyl, aryl, alkoxy or hydroxyalkyl; or NR4R5 = a 5-6 membered heterocyclic ring; providing that at least one of R1, R4 and R5 = hydroxyalkyl.

公开(公告)号：DE50012953D1

公开(公告)日：2006-07-27

申请号：DE50012953

申请日：2000-05-24

Applicant: BASF AG

Inventor： KINDLER ALOIS DR ,  PREISS THOMAS DR ,  HENKELMANN JOCHEM DR

IPC: B01J31/02 ,  C07C29/42 ,  C07B61/00 ,  C07C33/044 ,  C07C33/046

Abstract: Alkyne diol preparation from a carbonyl compound and acetylene uses an alkali metal salt prepared in situ as an alcoholate a catalyst. Preparation of alkyne diol of formula (I)comprises reacting a carbonyl compound of formula (II) with acetylene in the prese of an alkali metal salt as catalyst and a polar aprotic solvent. R R C(OH)-C IDENTICAL C-C(OH)R R (I) R -C(=O)-R (II) R and R = H or 1-20C hydrocarbon optionally substituted by 1-6C alkyl and/or halogen and/or interrupted by halogen and/or containing a CC double or triple bond.

公开(公告)号：DE19642553A1

公开(公告)日：1998-04-16

申请号：DE19642553

申请日：1996-10-15

Applicant: BASF AG

Inventor： PREISS THOMAS DR ,  HENKELMANN JOCHEM DR ,  WULFF-DOERING JOACHIM DR ,  STUTZ SUSANNE DR ,  RUEHL THOMAS DR

IPC: C07B61/00 ,  C07C213/00 ,  C07C213/02 ,  C07C215/08 ,  C07C217/08 ,  B01J23/72 ,  C07C215/14

Abstract: Preparation of N-hydroxyalkyl -substituted amino-alkynol derivatives of formula (I) involves reaction of an alkyne of formula R1-C IDENTICAL CH (II) with a 1-oxa-3-aza-heterocycloalkane of formula (III) over a heterogeneous catalyst comprising a compound of a first or second transition group metal. R1= H, alkyl, haloalkyl, cycloalkyl, aryl, alkoxy, alkoxyalkyl, hydroxyalkyl or -CR2R3-N(R4)-A-OH; R2-R4 = H, alkyl, haloalkyl, cycloalkyl, aryl, alkoxy, alkoxyalkyl or hydroxyalkyl; A = 2-5C alkylene (optionally substituted by one or more of alkyl, haloalkyl, aryl, alkoxy, hydroxy and hydroxyalkyl).

公开(公告)号：ES2151216T3

公开(公告)日：2000-12-16

申请号：ES97117797

申请日：1997-10-14

Applicant: BASF AG

Inventor： PREISS THOMAS DR ,  HENKELMANN JOCHEM DR ,  WULFF-DORING JOACHIM DR ,  STUTZ SUSANNE DR ,  RUHL THOMAS DR

IPC: C07B61/00 ,  C07C213/00 ,  B01J23/72 ,  C07C213/02 ,  C07C215/08 ,  C07C217/08

Abstract: Preparation of N-hydroxyalkyl -substituted amino-alkynol derivatives of formula (I) involves reaction of an alkyne of formula R1-C IDENTICAL CH (II) with a 1-oxa-3-aza-heterocycloalkane of formula (III) over a heterogeneous catalyst comprising a compound of a first or second transition group metal. R1= H, alkyl, haloalkyl, cycloalkyl, aryl, alkoxy, alkoxyalkyl, hydroxyalkyl or -CR2R3-N(R4)-A-OH; R2-R4 = H, alkyl, haloalkyl, cycloalkyl, aryl, alkoxy, alkoxyalkyl or hydroxyalkyl; A = 2-5C alkylene (optionally substituted by one or more of alkyl, haloalkyl, aryl, alkoxy, hydroxy and hydroxyalkyl).

公开(公告)号：DE19753458A1

公开(公告)日：1999-06-10

申请号：DE19753458

申请日：1997-12-02

Applicant: BASF AG

Inventor： BOETTCHER ARND DR ,  HENKELMANN JOCHEM DR ,  PREISS THOMAS DR ,  BRUNNER MELANIE DR

IPC: B01J23/84 ,  B01J31/22 ,  C07B61/00 ,  C07C29/42 ,  C07C33/042 ,  C07C209/60 ,  C07C211/23 ,  C07C213/00 ,  C07C213/02 ,  C07C215/24 ,  B01J31/00 ,  C07B43/04 ,  C07C41/26 ,  C07C211/20 ,  C07C215/22 ,  C07D211/04 ,  C07D295/04

Abstract: The invention relates to a method for preparing a catalyst through activation of a catalytic material comprising a) at least one metal from the first or second side group or one compound thereof and b) optionally a carrier. This catalyst is characterised in that the material is treated with an alkine of formula (I): R1-CC-R , in which R represents alkyl, cycloalkyl, aryl, hydroxyalkyl, alkyl halide, alkoxy or alkoxyalkyl, R represents hydrogen, alkyl, cycloalkyl or aryl, as well as with a carbonyl compound of formula (II), in which R and R represent independently from each other hydrogen, alkyl, alkyl halide, cycloalkyl or aryl. The invention also relates to catalysts obtained according to said method, and to alkinylations and aminoalkylations using said catalysts.

公开(公告)号：DE19636078A1

公开(公告)日：1998-03-12

申请号：DE19636078

申请日：1996-09-05

Applicant: BASF AG

Inventor： PREISS THOMAS DR ,  HENKELMANN JOCHEM DR ,  WULFF-DOERING JOACHIM DR ,  STUTZ SUSANNE DR

IPC: C07D295/04 ,  B01J31/26 ,  C07C209/60 ,  C07C211/08 ,  C07C211/23 ,  C07C211/25 ,  C07C211/26 ,  C07C211/43 ,  C07C211/54 ,  C07C211/21

Abstract: Preparation of N-alkyl-substituted amino-alkynes of formula R1-C IDENTICAL C-CR2R3-NR4R5 comprises the heterogeneous reaction of an alkyne of formula R1-C IDENTICAL CH, a carbonyl compound of formula R2R3C=O and an amine of formula R4-NH-R5 using an unsupported copper catalyst derived from malachite. R1 = H, alkyl, haloalkyl, cycloalkyl, aryl, alkoxy, alkoxyalkyl or hydroxyalkyl; R2, R3 = H, alkyl, haloalkyl, aryl or alkoxy; R4, R5 = H, alkyl, haloalkyl, aryl, alkoxy or hydroxyalkyl; or NR4R5 = a 5-6 membered heterocycle.

公开(公告)号：DE19734445A1

公开(公告)日：1999-02-11

申请号：DE19734445

申请日：1997-08-08

Applicant: BASF AG

Inventor： KELLER HARALD DR ,  SCHEHLMANN VOLKER DR ,  WESTENFELDER HORST ,  PREISS THOMAS DR

IPC: A61K8/00 ,  A61K8/90 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q5/00 ,  A61Q17/04 ,  C08F216/14 ,  C08F216/16 ,  C08F216/18 ,  C08F218/00 ,  C08F218/10 ,  C08F220/36 ,  C09K3/00 ,  G02B1/04 ,  C08F216/12 ,  C08F220/10 ,  C08F218/04 ,  A61K7/42

Abstract: Polymeric UV absorbers based on units of formula (I) are new, where a+b+c+d = 100; a, c = 5-95; b, d = 0-70; R , R = H or 1-8C alkyl; R = 3-hydroxy-4-benzoylphenoxy, a benzoyloxy group substituted in the 2-position by N(X )(X ), a group of formula (i)-(iv), 2-hydroxybenzoyloxy, 4-(2-oxo-3-bornylidenemethyl)phenoxy, 3-hydroxy-4-(benzylÄbÜ1,2,3-triazol-2-yl)phenoxy or 4-hydroxy-3-(benzylÄbÜ1,2,3-triazol-2-yl)benzoyloxy; X -X = H or 1-8C alkyl; R = (CO)n-R ; R = 1-28C alkyl; n = 0 or 1; R = 1-22C alkyl; R = H or CH3; and R (sic) = H or CH3.

公开(公告)号：DE19715667A1

公开(公告)日：1998-10-22

申请号：DE19715667

申请日：1997-04-15

Applicant: BASF AG

Inventor： HENKELMANN JOCHEM DR ,  PREISS THOMAS DR ,  BOETTCHER ARND DR

IPC: C07B61/00 ,  C07F9/38 ,  C07F9/40 ,  C07F9/32

Abstract: The invention relates to a method for producing vinyl phosphonic acid compounds of general formula (I) wherein R and R are independently H, C1-16-aryl, C7-12-alkaryl or C7-12-aralkyl radicals, wherein the organic radicals can be substituted by one or several halogen atoms, hydroxyl, acyl or acetoxy groups. Production occurs by reacting phosphoric acid compounds of general formula (II) with acetylene in the presence of a Pd(II) complex and/or a Pd(0) complex or corresponding Pt complexes as a catalyst.

公开(公告)号：DE19544408A1

公开(公告)日：1997-06-05

申请号：DE19544408

申请日：1995-11-29

Applicant: BASF AG

Inventor： HEIDER MARC DR ,  PREISS THOMAS DR ,  HENKELMANN JOCHEM DR ,  RUETTER HEINZ DR ,  SCHAEFER MARTIN DR ,  HOEHN ARTHUR DR

IPC: C07D315/00 ,  C07D307/33 ,  C07B41/00

Abstract: A method (a) of preparing butyrolactones of formula (I) comprises reacting an alkyne of formula R -C?=C-R (II) with CO and H2 or H2 formed in situ at elevated pressure and temp. in the presence of a transition metal catalyst. R , R = H, (hydroxy)alkyl or trialkylsilyl or aryl gps., opt. with inert substits. Also claimed is a second method (b) of preparing the corresp. 2-(5H)-furanones of formula (III) which comprises reacting (II) with CO and H2 gas in the presence of transition metal catalysts and amine bases at 60-140 deg C and a H2 partial pressure of > 50 bar. (III) may then be hydrogenated to (I) in a separate hydrogenation reaction.