公开(公告)号：JPH1067717A

公开(公告)日：1998-03-10

申请号：JP11326997

申请日：1997-05-01

Applicant: BASF AG

Inventor： RUEHL THOMAS DR ,  PREISS THOMAS DR ,  HENKELMANN JOCHEM DR

IPC: B01J31/26 ,  C07B61/00 ,  C07C213/02 ,  C07C213/08 ,  C07C215/08 ,  C07C215/12 ,  C07C215/24 ,  C07C217/08 ,  C07C217/46

Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound in a high yield by the reaction of an alkyne with a carbonyl compound and an amine in the presence of a heterogeneous catalyst. SOLUTION: This compound, a hydroxyalkyl-substituted aminoalkyne of formula IV [e.g. 3-(di-2-hydroxyethylamino)propyne], is obtained by reaction of an alkyne of formula I (R1 is H, an alkyl, hydroxyalkyl, etc.) with a carbonyl compound of formula II (R2 and R3 are each H, an alkyl, aryl, alkoxy, etc..) and an amine of formula III (R4 and R5 are each H, an alkyl, hydroxyalkyl, etc., or joined together with a bound N atom to form a five- or six-membered ring) in the presence of a heterogeneous catalyst such as an acetylated copper catalyst carried on a bismuth-doped silicate support. By virtue of this method, the objective desired aminoalkyne can be obtained in high yield without the need of any special means for pH adjustment.

公开(公告)号：JP2002179691A

公开(公告)日：2002-06-26

申请号：JP2001338322

申请日：2001-11-02

Applicant: BASF AG

Inventor： HENKELMANN JOCHEM DR ,  KLASS KATRIN ,  ARNDT JAN-DIRK

IPC: B01J31/24 ,  C07F9/40

Abstract: PROBLEM TO BE SOLVED: To provide an improved method for producing an alkenylphosphonic acid derivative. SOLUTION: This method for producing the alkenylphosphonic acid derivative comprises reacting a phosphonic acid derivative with an alkyne in the presence of a metal complex catalyst system containing (a) nickel and (b) a phosphine having at least two trivalent phosphorus atoms.

公开(公告)号：JP2000044492A

公开(公告)日：2000-02-15

申请号：JP20331099

申请日：1999-07-16

Applicant: BASF AG

Inventor： BREITSCHEIDEL BORIS DR ,  DIEHLMANN UWE ,  KINDLER ALOIS DR ,  HENKELMANN JOCHEM DR ,  BOETTCHER ARND DR

IPC: B01J23/44 ,  B01J21/02 ,  B01J35/10 ,  C07B31/00 ,  C07B35/02 ,  C07B61/00 ,  C08F8/04

Abstract: PROBLEM TO BE SOLVED: To obtain a further improved method for reacting an organic compound, especially selectively hydrogenating a polymer having a C-C multiple bond. SOLUTION: This method for reacting an organic compound on a macroporous carrier catalyst containing a boron oxide is a method for reacting the organic compound in the presence of a catalyst containing as an active metal loaded on a carrier having macropores, at least only one kind of a transition metal of the VIII group of the Periodic Table, or together with at least one kind of a transition metal of the I or VII group of the Periodic Table in 0.01 to 30 wt.% based on the total weight of the catalyst, and as the component of the carrier, boron(III) oxide is contained in a mass ratio of 10 to 100 wt.% based on the total weight of the carrier.

公开(公告)号：JP2005132840A

公开(公告)日：2005-05-26

申请号：JP2004311068

申请日：2004-10-26

Applicant: Basf Ag ,  ビーエーエスエフ アクチェンゲゼルシャフト

Inventor： KESSINGER ROLAND ,  ARNDT JAN-DIRK ,  HENKELMANN JOCHEM DR ,  THOMAS FLORIAN

IPC: C07F9/40 ,  C07F9/50 ,  C07F15/04

CPC classification number: C07F9/4015

Abstract: PROBLEM TO BE SOLVED: To provide a process for preparation of an alkenylphosphonic acid derivative.
SOLUTION: The invention relates to the process for preparation of the alkenylphosphonic acid derivative comprising reaction of a phosphonic acid derivative and an alkyne in the presence of a complex catalyst system, wherein the complex catalyst system comprises (a) nickel, (b) a phosphine having at least two trivalent phosphorus atoms and additionally (c) a phosphine having a trivalent phosphorus atom.
COPYRIGHT: (C)2005,JPO&NCIPI

Abstract translation: 待解决的问题：提供烯基膦酸衍生物的制备方法。 解决方案：本发明涉及烯基膦酸衍生物的制备方法，其包括在络合催化剂体系存在下膦酸衍生物和炔烃的反应，其中复合催化剂体系包含（a）镍，（b ）具有至少两个三价磷原子的膦，另外（c）具有三价磷原子的膦。 版权所有（C）2005，JPO＆NCIPI

公开(公告)号：JP2001233855A

公开(公告)日：2001-08-28

申请号：JP2001049221

申请日：2001-02-23

Applicant: BASF AG

Inventor： HENKELMANN JOCHEM DR ,  ARNDT JAN-DIRK

IPC: C07B61/00 ,  C07D209/08 ,  C07D209/12 ,  C07D209/14 ,  C07D209/18 ,  C07D209/40 ,  C07D409/04 ,  C07D417/04 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing an indole type compound of formula (I) (A, R1 and R2 are each mentioned in the claim 1) by the cyclization of an alkynylamino aromatic compound of formula (II). SOLUTION: The reaction is carried out in the presence of the proper compound of Na, K, Rb or Cs in a polar aprotic solvent. The substituted indole compound can be produced in a high yield by the simple method.

公开(公告)号：JP2001002606A

公开(公告)日：2001-01-09

申请号：JP2000151403

申请日：2000-05-23

Applicant: BASF AG

Inventor： AISCAR BAYETO JUAN JOSE ,  HENKELMANN JOCHEM DR ,  PREISS THOMAS DR ,  KNOCHEL PAUL ,  TZALIS DIMITRIOS ,  KORADIN CHRISTOPHER

IPC: B01J23/04 ,  C07B61/00 ,  C07C29/38 ,  C07C29/42 ,  C07C33/042 ,  C07C33/30 ,  C07C35/17 ,  C07C35/21 ,  C07C41/30 ,  C07C43/178 ,  C07C213/00 ,  C07C215/24 ,  C07C215/26 ,  C07C215/42

Abstract: PROBLEM TO BE SOLVED: To produce an alkyne compound through an improved generally applicable process by reacting a carbonyl-containing compound with an acetylenic group-containing compound in the presence of a specific basic catalyst. SOLUTION: (A) A compound of the formula: R1C(=O)R2 [R1 and R2 are each H or a (substituted or interrupted with non-adjacent hetero atom, or containing a C=C bond) 1-20C hydrocarbon; at least one of R1 and R2 is not H] is made to react with (B) a compound of the formula HC≡CR3 [R3 is H or a (substituted or interrupted with non-adjacent hetero atom, or containing a C=C bond) 1-20C hydrocarbon] in the presence of (C) a basic catalyst consisting of CsOH.H2O optionally in (D) an N-methylpyrrolidone-based solvent to obtain the objective compound of the formula R1R2C(OH)C≡CR3.

公开(公告)号：JP2000169408A

公开(公告)日：2000-06-20

申请号：JP34913799

申请日：1999-12-08

Applicant: BASF AG

Inventor： RAHN RALF-THOMAS ,  RUST HARALD ,  RUEHL THOMAS DR ,  HENKELMANN JOCHEM DR ,  STUTZ SUSANNE DR

IPC: C07C29/82 ,  C07C29/16 ,  C07C29/80 ,  C07C33/025 ,  C07C33/042 ,  C07C33/048

Abstract: PROBLEM TO BE SOLVED: To provide a continuous distillation method having excellent economic efficiency, guaranteeing safety of high level in the case of isolating α- ethynylcarbinol on an industrial scale. SOLUTION: α-Ethynylcarbinol is isolated from a liquid reaction mixture obtained by adding acetylene to an α,β-unsaturated carbonyl compound by a continuous distillation comprising introducing a feed stream to the central part of a distillation column, azeotropically distilling away most of water together with a solvent at the top of the column and taking out α- ethynylcarbinol of the objective product at a part below the feeding part to the column.

公开(公告)号：JPH10316591A

公开(公告)日：1998-12-02

申请号：JP33877697

申请日：1997-12-09

Applicant: BASF AG

Inventor： BREITSCHEIDEL BORIS DR ,  RUEHL THOMAS DR ,  FLICK KLEMENS DR ,  HENKELMANN JOCHEM DR ,  HENNE ANDREAS DR ,  LEBKUECHER ROLF DR

IPC: B01J23/36 ,  B01J23/40 ,  B01J23/46 ,  B01J23/72 ,  B01J23/75 ,  B01J23/755 ,  B01J35/10 ,  B01J37/00 ,  C07B35/02 ,  C07B61/00 ,  C07C29/20 ,  C07C35/08 ,  C07C209/72 ,  C07C211/35

Abstract: PROBLEM TO BE SOLVED: To provide a process for hydrogenating an aromatic compound, enabling to perfectly hydrogenate the aromatic compound in a high yield. SOLUTION: This process for hydrogenating an aromatic compound in which a least one hydroxyl group is bonded to an aromatic ring or an aromatic compound in which at least one amino group is bonded to an aromatic ring, in the presence of a catalyst comprising, as catalytically active component, at least one metal of transition group I, VII or VIII of the periodic table applied to a support, wherein the catalyst is obtainable by (a) dissolving the catalytically active compound or a precursor compound thereof in a solvent, (b) admixing the solution thus obtained with an organic polymer which is able to bind at least ten times its own weight of water, giving a swollen polymer, (c) subsequently mixing the swollen polymer with a catalyst support material and (d) shaping, drying and calcining the composition obtained in this way.

公开(公告)号：JPH10120633A

公开(公告)日：1998-05-12

申请号：JP28191897

申请日：1997-10-15

Applicant: BASF AG

Inventor： PREISS THOMAS DR ,  HENKELMANN JOCHEM DR ,  WULFF-DOERING JOACHIM DR ,  STUTZ SUSANNE DR ,  RUEHL THOMAS DR

IPC: B01J23/72 ,  C07B61/00 ,  C07C213/00 ,  C07C213/02 ,  C07C215/08 ,  C07C217/08

Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound under low pressure by using a catalyst containing metal compounds of a first and a second subgroup elements and gaseous C2 H2 , etc., when carrying out the reaction of an alkyd with a 1-oxa-3- azaheterocycloalkane. SOLUTION: An N-hydroxyalkyl substituted aminoalkyne expressed by formula II is manufactured by reacting a mixture of a compound expressed by the formula R -C≡C-H(R is H, an alkyl, etc.) and a compound expressed by formula I (R , R are each H, an alkyl, etc.; A is a 2-5 alkylene) in the presence of a catalyst containing a metal compound of a first subgroup elements under a heterogeneous catalytic system. A suitable catalyst contains a complex of copper acetylide and Bi compound, for example, (BiO)2 CO3 , etc., the preferable catalyst contains about 40-70wt.% of Cu and about 0.1-10% of Bi. The reaction is carried out in a reactor such as a tubular reactor, etc., provided with a stirrer, generally at 0-200 deg.C, preferably at 20-120 deg.C, especially preferably at 40-120 deg.C.

公开(公告)号：JP2001002614A

公开(公告)日：2001-01-09

申请号：JP2000151402

申请日：2000-05-23

Applicant: BASF AG

Inventor： AISCAR BAYETO JUAN JOSE ,  HENKELMANN JOCHEM DR ,  PREISS THOMAS DR ,  KNOCHEL PAUL ,  TZALIS DIMITRIOS ,  KORADIN CHRISTOPHER

IPC: C07B37/02 ,  C07B41/04 ,  C07B43/04 ,  C07B61/00 ,  C07C41/08 ,  C07C43/166 ,  C07C67/347 ,  C07C209/60 ,  C07C211/55 ,  C07C253/30 ,  C07C255/34 ,  C07D207/32 ,  C07D207/323 ,  C07D209/08 ,  C07D233/58 ,  C07D235/06 ,  C07D235/08 ,  C07D521/00

Abstract: PROBLEM TO BE SOLVED: To obtain an alkene compound in an improved and generally utilizable way by reacting an organic compound having at least one amino group, hydroxyl group and/or nitrile group with a compound having at least one acetylene group. SOLUTION: The objective compound of the formula R3-HC=CR2-R4 [wherein R2 and R3 are each H, NH2 or a (substituted) 1-20C hydrocarbon which may be interrupted by at least one nonadjacent heteroatom or may have at least one C-C double bond; R4 is R5R6N, R5R6C(Z) or R7O; R5 to R7 are each NH2 or a (substituted) 1-20C hydrocarbon which may be interrupted by at least one nonadjacent heteroatom or may have at least one C-C double bond; R7O is not a 1,2-aminoalkanol; and Z is CN or COOR (wherein R is H or a 1-6C alkyl)] is obtained by reacting (A) an alkene compound of the formula R4-H except 1,2-aminoalkanols with (B) a compound of the formula R2-C≡C-R3 in the presence of (C) CsOH.H2O as one kind of basic catalyst.