公开(公告)号：CZ185197A3

公开(公告)日：1998-03-18

申请号：CZ185197

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG DR ,  MAIER WERNER ,  BREITENBACH JORG DR

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05119 Sec. 371 Date Jun. 20, 1997 Sec. 102(e) Date Jun. 20, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19964 PCT Pub. Date Jul. 4, 1996The present invention relates to a process for the production of lenticular tablets by melt calendering in which molding rolls with depressions in the shape of segments of an ellipsoid are used. The process according to the invention affords tablets which are easily deflashed and in which the tablet residue to be abraded when there is a displacement between the upper and lower half of the tablet is small.

公开(公告)号：DE19629040A1

公开(公告)日：1998-01-22

申请号：DE19629040

申请日：1996-07-19

Applicant: BASF AG

Inventor： BERNDL GUNTHER DR ,  ROSENBERG JOERG DR ,  SANNER AXEL DR

IPC: A61K9/16 ,  A61K9/20 ,  A61K36/00 ,  A61K36/16 ,  A61K36/38 ,  A61K36/48 ,  A61K36/61 ,  A61K35/78

Abstract: The invention concerns solid active substance preparations containing as active substances plant extracts, with the exception of extracts of Gingko biloba, Glycyrrhiza glabra and Eucalyptus globulus. The preparations are obtained by extruding a mixture of at least one plant extract and at least one meltable polymer and subsequent shaping.

公开(公告)号：DE19509806A1

公开(公告)日：1996-09-26

申请号：DE19509806

申请日：1995-03-21

Applicant: BASF AG

Inventor： BREITENBACH JOERG DR ,  RIEGER JENS DR ,  ROSENBERG JOERG DR ,  SANNER AXEL DR

IPC: A61K9/20 ,  A61K9/16 ,  A61K47/30 ,  A61K31/485

Abstract: Solid medicaments obtainable by the extrusion of a melt, containing a mixture of homo and/or copolymers of N-vinyl pyrrolidone and degraded starches besides one or more active agents.

公开(公告)号：DE4446467A1

公开(公告)日：1996-06-27

申请号：DE4446467

申请日：1994-12-23

Applicant: BASF AG

Inventor： ROSENBERG JOERG DR ,  MAIER WERNER ,  BREITENBACH JOERG DR

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: The invention concerns a method of producing lenticular tablets by melt calendering, using form cylinders provided with ellipsoid-segment recesses. The proposed method produces tablets which are easy to trim and in which any misalignement between the top and bottom halves of the tablet is such that only a small residue needs to be ground off.

公开(公告)号：CZ300895A3

公开(公告)日：1996-02-14

申请号：CZ300895

申请日：1994-05-09

Applicant: BASF AG

Inventor： GRABOWSKI SVEN DR ,  MUELLER WINFRIED DR ,  ROSENBERG JOERG DR ,  BINDER RUDOLF DR ,  SANNER AXEL DR

IPC: A61K47/32 ,  A61K9/14 ,  A61K31/37 ,  A61K31/41 ,  A61K31/425 ,  A61K31/433 ,  A61K47/30 ,  A61K47/38

Abstract: PCT No. PCT/EP94/01489 Sec. 371 Date Nov. 7, 1995 Sec. 102(e) Date Nov. 7, 1995 PCT Filed May 9, 1994 PCT Pub. No. WO94/26267 PCT Pub. Date Nov. 24, 1994Compositions in the form of solid solutions containing a) 1-90% by weight of a coumarin derivative A from the group of alkoxycoumarins with a heterocyclic substituent or of hydroxycoumarins esterified with a sulfonic acid as active substance and b) 10-99% by weight of at least one water-soluble polymer B as carrier substance.

公开(公告)号：DE4316537A1

公开(公告)日：1994-11-24

申请号：DE4316537

申请日：1993-05-18

Applicant: BASF AG

Inventor： GRABOWSKI SVEN DR ,  MUELLER WINFRIED DR ,  ROSENBERG JOERG DR ,  BINDER RUDOLF DR ,  SANNER AXEL DR

IPC: A61K47/32 ,  A61K9/14 ,  A61K31/37 ,  A61K31/41 ,  A61K31/425 ,  A61K31/433 ,  A61K47/30 ,  A61K47/38 ,  A61K31/35

Abstract: PCT No. PCT/EP94/01489 Sec. 371 Date Nov. 7, 1995 Sec. 102(e) Date Nov. 7, 1995 PCT Filed May 9, 1994 PCT Pub. No. WO94/26267 PCT Pub. Date Nov. 24, 1994Compositions in the form of solid solutions containing a) 1-90% by weight of a coumarin derivative A from the group of alkoxycoumarins with a heterocyclic substituent or of hydroxycoumarins esterified with a sulfonic acid as active substance and b) 10-99% by weight of at least one water-soluble polymer B as carrier substance.

公开(公告)号：CZ9800959A3

公开(公告)日：1998-08-12

申请号：CZ95998

申请日：1996-09-30

Applicant: BASF AG

Inventor： ZEIDLER JURGEN DR ,  ROSENBERG JOERG DR ,  NEUMANN JORG DR ,  BREITENBACH JORG DR

IPC: A61K9/16 ,  A61K9/20 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30

CPC classification number: A61K9/2027 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2095 ,  A61K31/277

公开(公告)号：CZ9801242A3

公开(公告)日：1998-07-15

申请号：CZ124298

申请日：1996-10-23

Applicant: BASF AG

Inventor： BREITENBACH JORG DR ,  HARTL AXEL PAUL DR ,  HOFMANN JURGEN ,  ROSENBERG JOERG DR ,  SCHIESSL MICHAEL ,  ZETTLER HANS DIETER

IPC: A61J3/10 ,  A61K9/20 ,  A61K9/24 ,  A61K9/28 ,  A61K31/07 ,  A61K31/167 ,  A61K31/192 ,  A61K31/277 ,  A61K31/355 ,  A61K31/375 ,  A61K31/401 ,  A61K31/4422 ,  A61K31/52 ,  A61K31/522 ,  A61K31/60

CPC classification number: A61J3/10 ,  A61J2200/20 ,  A61K9/209 ,  A61K9/2095 ,  A61K9/2893 ,  A61K31/07 ,  A61K31/167 ,  A61K31/192 ,  A61K31/277 ,  A61K31/355 ,  A61K31/375 ,  A61K31/401 ,  A61K31/4422 ,  A61K31/52 ,  A61K31/522 ,  A61K31/616 ,  B30B11/14 ,  B30B11/16 ,  B30B11/18 ,  B30B11/34 ,  B30B15/308 ,  A61K31/19 ,  A61K2300/00

公开(公告)号：CZ280297A3

公开(公告)日：1998-03-18

申请号：CZ280297

申请日：1996-03-09

Applicant: BASF AG

Inventor： BREITENBACH JORG DR ,  SANNER AXEL DR ,  ROSENBERG JOERG DR

IPC: A61K9/00 ,  A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K47/30

Abstract: PCT No. PCT/EP96/01021 Sec. 371 Date Sep. 16, 1997 Sec. 102(e) Date Sep. 16, 1997 PCT Filed Mar. 9, 1996 PCT Pub. No. WO96/29053 PCT Pub. Date Sep. 26, 1996Transparent rapid release active substance compositions obtainable by extrusion of melts, containing non-steroidal analgesics, homopolymers of N-vinylpyrrolidone, saccharides or sugar alcohols and sodium or potassium salts.

公开(公告)号：CZ9702394A3

公开(公告)日：1998-01-14

申请号：CZ239497

申请日：1996-02-01

Applicant: BASF AG

Inventor： GRABOWSKI SVEN DR ,  BREITENBACH JORG DR ,  ROSENBERG JOERG DR ,  SANNER AXEL DR

IPC: A61K9/22 ,  A61K9/20

CPC classification number: A61K9/2054 ,  A61K9/2095