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11.发明专利
公开(公告)号：CA2774621A1
公开(公告)日：2011-03-24
申请号：CA2774621
申请日：2010-09-17
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： BOULAROT NICOLAS , GENET MAGALIE , SCHWARZ FRANCE
IPC: A61B1/04
Abstract: A method to inspect a solid organ in a subject includes introducing a needle in a predetermined area of the solid organ, inserting an optical probe through a lumen of the needle, and imaging the predetermined area using the optical probe. An optical probe to inspect a solid organ in a subject, the optical probe being intended to be positioned in the solid organ through a needle, the optical probe includes an optical fiber bundle, a ferule to protect the distal tip of the optical fiber bundle, the ferule comprising a shank and a head, and a sheath wrapping the fiber bundle and the shank, wherein the head of the ferule has a length adapted for the optical probe to image the solid organ while keeping the sheath inside the needle.
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公开(公告)号：FR2900741B1
公开(公告)日：2008-07-18
申请号：FR0604019
申请日：2006-05-05
Applicant: MAUNA KEA TECHNOLOGIES SOC PAR
Inventor： GENET MAGALIE , MATHIEU GILLES , VIELLEROBE BERTRAND , DOUSSOUX FRANCOIS , BOULAROT NICOLAS , LAVILLONNIERE NICOLAS
Abstract: A miniaturized optical head provided to equip the distal end of a beam of flexible optical fibers scanned by a laser beam, is designed to come in contact with a sample and to excite the sample confocally. This optical head includes elements for correcting spherical aberrations and focusing members. The focusing members include: at least a first lens (L4) of high convergence associated with a spherical or hemispherical lens (L5) arranged at the distal end of the optical head, and elements for correcting the axial and lateral chromatic aberration provided with a single divergent lens (3b) whose curvature is substantially centered on the pupil of the optical fiber beam and arranged at the exact distance for this pupil for which the conditions of lateral achromatization coincide with the conditions of axial achromatization; this divergent lens being associated with a second convergent lens (L3a) in the form of a doublet (L3).
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公开(公告)号：ES2410538T3
公开(公告)日：2013-07-02
申请号：ES07731377
申请日：2007-04-27
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： GENET MAGALIE , MATHIEU GILLES , VIELLEROBE BERTRAND , DOUSSOUX FRANCOIS , BOULAROT NICOLAS , LAVILLONNIERE NICOLAS
Abstract: Cabezal óptico miniaturizado previsto para equipar el extremo distal de un haz de fibras ópticas flexibles barridopor un haz láser, estando dicho cabezal óptico destinado a entrar en contacto con una muestra y excitar dichamuestra de manera confocal; comprendiendo este cabezal óptico un bloque óptico de corrección de aberracionesesféricas y un bloque óptico de enfoque; caracterizado porque el bloque de enfoque comprende: - al menos una primera lente convergente (4; 18, 19) asociada con una lente esférica o semiesférica (5; 10)dispuesta en el extremo distal del cabezal óptico, y - medios de corrección del cromatismo axial y lateral que se proporcionan con una sola lente divergente (3b) quetiene una curvatura centrada sobre la pupila del haz de fibras ópticas; estando esta lente divergente asociada conuna segunda lente convergente (3a) en forma de un doblete (3; 17) comprendiendo el bloque de corrección de las aberraciones esféricas una tercera lente convergente (2); estando los espesores de la primera (4) y tercera (2) lentes convergentes dispuestos para corregir la aberraciónesférica acumulada sobre las dioptrías convergentes, estando también el espesor de la tercera lente convergente (2) dispuesto para obtener imágenes de la pupila sobrela segunda lente convergente (3).
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14.发明专利
公开(公告)号：AU2010296946A1
公开(公告)日：2012-05-03
申请号：AU2010296946
申请日：2010-09-17
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： BOULAROT NICOLAS , GENET MAGALIE , SCHWARZ FRANCE
IPC: A61B1/04
Abstract: A method to inspect a solid organ in a subject includes introducing a needle in a predetermined area of the solid organ, inserting an optical probe through a lumen of the needle, and imaging the predetermined area using the optical probe. An optical probe to inspect a solid organ in a subject, the optical probe being intended to be positioned in the solid organ through a needle, the optical probe includes an optical fiber bundle, a ferule to protect the distal tip of the optical fiber bundle, the ferule comprising a shank and a head, and a sheath wrapping the fiber bundle and the shank, wherein the head of the ferule has a length adapted for the optical probe to image the solid organ while keeping the sheath inside the needle.
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公开(公告)号：CA2769607A1
公开(公告)日：2011-02-03
申请号：CA2769607
申请日：2010-07-19
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： BOULAROT NICOLAS , CRESSANT ARNAUD
Abstract: An intracranial implant to position a fiber bundle to a specified region of a brain of an animal. The implant may include a base support to be fixed to a skull of the animal over an orifice drilled in the skull, a hollow conduit arranged through the base support to guide the fiber bundle to the brain of the animal through the drilled orifice and a first locking member arranged on the base support, to cooperate with a ferrule of the fiber bundle, the first locking member configured to lock the fiber bundle to the specified region of the brain of the animal.
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Patent Agency Ranking16.发明专利
公开(公告)号：FR2922308A1
公开(公告)日：2009-04-17
申请号：FR0758236
申请日：2007-10-11
Applicant: MAUNA KEA TECHNOLOGIES SOC PAR
Inventor： VIELLEROBE BERTRAND , LACOMBE FRANCOIS , BOULAROT NICOLAS , DOUSSOUX FRANCOIS , LAVILLONNIERE NICOLAS
Abstract: La présente invention concerne un dispositif d'imagerie, comprenant : un module d'illumination (1) comprenant des moyens pour émettre au moins un faisceau d'excitation ; un module de balayage et d'injection (2) comprenant un guide d'image (3) dont deux extrémités respectivement proximale (3a) et distale (3b) sont reliées par une pluralité de fibres optiques, et des moyens (6) de balayage et d'injection agencés pour injecter l'au moins un faisceau d'excitation tour à tour dans une fibre du guide d'image (3) et du côté proximal (3a) du guide ; un module de détection (4) comprenant des moyens pour détecter un flux lumineux (14) collecté à l'extrémité distale (3b) du guide. Au moins un parmi le module d'illumination (1) et le module de détection (4) est conjugué optiquement au module de balayage et d'injection (2) par une fibre optique de conjugaison (5, 7). L'utilisation de fibres de conjugaison (5, 7) permet d'améliorer la maintenance, la réparation et la mise à jour du dispositif, et peut en outre permettre de réaliser un filtrage modal du faisceau d'excitation et d'assurer la confocalité du dispositif.
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公开(公告)号：ES2524480T3
公开(公告)日：2014-12-09
申请号：ES10768547
申请日：2010-07-19
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： BOULAROT NICOLAS , CRESSANT ARNAUD
Abstract: Un implante intracraneal (1) para colocar un manojo de fibras de una sonda de manojo de fibras en una región especificada de un cerebro de un animal, en donde la sonda de manojo de fibras comprende además un casquillo dispuesto en una parte distal del manojo de fibras, el implante intracraneal (1) comprende: un soporte de base (11) para ser fijado a un cráneo del animal sobre un orificio taladrado en el cráneo; un conducto hueco (12) dispuesto a través de la base de soporte (11) para guiar el manojo de fibras al cerebro del animal a través del orificio taladrado; un primer miembro de trabado (100) dispuesto en la base de soporte (11), para cooperar con el casquillo de la sonda de manojo de fibras, el primer miembro de trabado (100) se configura para trabar el manojo de fibras en la región especificada del cerebro del animal, caracterizado porque el primer miembro de trabado (100) comprende un pasador (13) substancialmente perpendicular al soporte de base (11).
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公开(公告)号：AU2010277231A1
公开(公告)日：2012-03-08
申请号：AU2010277231
申请日：2010-07-19
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： BOULAROT NICOLAS , CRESSANT ARNAUD
Abstract: An intracranial implant to position a fiber bundle to a specified region of a brain of an animal. The implant may include a base support to be fixed to a skull of the animal over an orifice drilled in the skull, a hollow conduit arranged through the base support to guide the fiber bundle to the brain of the animal through the drilled orifice and a first locking member arranged on the base support, to cooperate with a ferrule of the fiber bundle, the first locking member configured to lock the fiber bundle to the specified region of the brain of the animal.
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公开(公告)号：CA2754863A1
公开(公告)日：2010-09-16
申请号：CA2754863
申请日：2010-03-12
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： ROCHER ALEXANDRA , DOUSSOUX FRANCOIS , CLADE SOPHIE , PETIT SYLVAIN , BOULAROT NICOLAS
Abstract: A connector to connect a fiber bundle probe to a light injection module including a tightening cam having an opening of a specified shape adapted to receive the fiber bundle probe, a cam driving coupled to the tightening cam, wherein the tightening cam is configured to translate in response to rotation of the cam driving until the tightening cam is blocked, at least one spring extending between the tightening cam and the cam driving, wherein the at least one spring is configured to resist when the cam driving is actuated by rotation and the tightening cam is blocked, and a locking mechanism to lock the cam driving into a selected position.
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20.发明专利
公开(公告)号：AU2008315834A1
公开(公告)日：2009-04-30
申请号：AU2008315834
申请日：2008-10-10
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： LAVILLONNIERE NICOLAS , DOUSSOUX FRANCOIS , BOULAROT NICOLAS , LACOMBE FRANCOIS , VIELLEROBE BERTRAND
Abstract: An imaging device includes an illumination module comprising at least one emitter for emitting at least one excitation beam; a scanning and injection module comprising an image guide, a proximal end and a distal end of which are linked by a plurality of optical fibers; a scanning and injection optical system configured to alternately inject the at least one excitation beam into an optical fiber of the image guide from the proximal end of the image guide; a detection module comprising a detector for detecting a luminous flux collected at the distal end of the image guide, wherein at least one of the illumination module and the detection module is optically conjugated with the scanning and injection module using a conjugating optical fiber.
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