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公开(公告)号：CA2841360A1
公开(公告)日：2013-01-24
申请号：CA2841360
申请日：2012-07-12
Applicant: MICELL TECHNOLOGIES INC
Inventor： MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , ZANI BRETT G , NEET JOHN , KIORPES TIMOTHY CHARLES
IPC: A61F2/06
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.
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公开(公告)号：CA2756307A1
公开(公告)日：2010-09-30
申请号：CA2756307
申请日：2010-03-22
Applicant: MICELL TECHNOLOGIES INC
Inventor： MCCLAIN JAMES B , TAYLOR DOUGLAS
Abstract: Provided herein is a coated coronary stent, comprising: a. stent; b. a plurality of layers deposited on said stent to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
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公开(公告)号：AU7594100A
公开(公告)日：2001-04-30
申请号：AU7594100
申请日：2000-09-20
Applicant: MICELL TECHNOLOGIES INC
Inventor： MCCLAIN JAMES B , COLE MICHAEL E , BRAINARD DAVID E , WORM STEVE L
Abstract: Cleaning apparatus having multiple wash tanks for washing articles in a carbon dioxide dry cleaning system employing a liquid carbon dioxide cleaning solution are provided. Cleaning apparatus having multiple wash tanks of the present invention may provide improved thermodynamic efficiency by allowing carbon dioxide vapor to be transferred between wash tanks rather than condensed. Cleaning apparatus having multiple wash tanks of the present invention may have a lower capital cost than multiple cleaning systems having single wash tanks. Cleaning apparatus having multiple wash tanks of the present invention include a first wash tank for contacting a first article with liquid carbon dioxide cleaning solution, and a second wash tank for contacting a second article with liquid carbon dioxide cleaning solution. The second wash tank is in fluid communication with the first wash tank. Methods of utilizing such cleaning apparatus are also provided. Coating apparatus having multiple coating tanks and methods of utilizing such coating apparatus are also provided.
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公开(公告)号：AU2732200A
公开(公告)日：2000-08-01
申请号：AU2732200
申请日：2000-01-19
Applicant: MICELL TECHNOLOGIES INC
Inventor： ROMACK TIMOTHY J , CAUBLE DAVID F , MCCLAIN JAMES B
Abstract: A method for dry-cleaning articles such as fabrics and clothing in carbon dioxide comprises contacting an article to be cleaned with a liquid dry cleaning composition for a time sufficient to clean the fabric. The liquid dry-cleaning composition comprises a mixture of carbon dioxide, a surfactant, and an organic co-solvent. After the contacting step, the article is separated from the liquid dry cleaning composition. The method is preferably carried out at ambient temperature. The surfactant is preferably one that does not contain a CO2-philic group. The organic co-solvent is preferably an alkane and has a flash point above 140° F.
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公开(公告)号：CA2912387C
公开(公告)日：2019-04-16
申请号：CA2912387
申请日：2014-05-15
Applicant: MICELL TECHNOLOGIES INC
Inventor： MCCLAIN JAMES B
Abstract: A bioabsorbable biomedical implant is disclosed. The implant includes a tubular scaffold comprising a plurality of interconnected polymer struts. The interconnected polymer struts defines a plurality of deformable cells. The polymer struts have an average thickness of no more than 150 µm. Methods for making the bioabsorbable biomedical implant, including the methods for making the fiber-reinforced polymer composite materials for the tubular scaffold, are also disclosed.
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Patent Agency Ranking
公开(公告)号：CA2810842C
公开(公告)日：2018-06-26
申请号：CA2810842
申请日：2011-09-09
Applicant: MICELL TECHNOLOGIES INC
Inventor： MCCLAIN JAMES B , CARLYLE WENDA C , TAYLOR CHARLES DOUGLAS
Abstract: Provided is a drug delivery composition comprising at least one polymer and at least one active agent; wherein the active agent is present in crystalline form on at least one region of an outer surface of the composition and wherein active agent surface content is adjusted to provide a selected active agent release profile.
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公开(公告)号：CA2977289A1
公开(公告)日：2018-03-23
申请号：CA2977289
申请日：2017-08-22
Applicant: MICELL TECHNOLOGIES INC
Inventor： KIORPES TIMOTHY CHARLES , MCCLAIN JAMES B
Abstract: A drug-eluting product is disclosed comprising an at least partially bioabsorbable element and an active pharmaceutical agent having a morphology, a solubility, and an average particle size which are selected so that the active pharmaceutical agent continues to dissolve during the biodegradation of the bioabsorbable element. The morphology is a crystalline, semi-crystalline or amorphous morphology, the solubility is less than 100 µg/ml and the average particle size is grater that about 100 nm.
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公开(公告)号：CA2922492C
公开(公告)日：2018-02-20
申请号：CA2922492
申请日：2006-06-21
Applicant: MICELL TECHNOLOGIES INC
Inventor： MCCLAIN JAMES B , DEYOUNG JAMES P
IPC: A61K9/00
Abstract: A method of forming a drug/polymer composite material is carried out by combining a drug material with a polymer material under pressure in the presence of a densified gas solvent (e.g., carbon dioxide) to form the drug/polymer composite material. Drug/polymer composite materials and shaped articles (e.g., subcutaneous drug depots) which may be produced by a process are also described, along with methods of use thereof.
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公开(公告)号：CA2730995C
公开(公告)日：2016-11-22
申请号：CA2730995
申请日：2009-07-16
Applicant: MICELL TECHNOLOGIES INC
Inventor： MCCLAIN JAMES B , TAYLOR DOUGLAS , NEET JOHN
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.
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公开(公告)号：HK1213503A1
公开(公告)日：2016-07-08
申请号：HK16101611
申请日：2016-02-15
Applicant: MICELL TECHNOLOGIES INC
Inventor： MCCLAIN JAMES B , TAYLOYR CHARLES DOUGLAS , FAGAN MEAGAN M
IPC: A61L20060101
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