公开(公告)号：AT279973T

公开(公告)日：2004-11-15

申请号：AT01116442

申请日：1999-08-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： TURNER HOWARD ,  DALES G CAMERON ,  VAN ERDEN LYNN ,  VAN BEEK JOHANNES A M ,  HAJDUK DAMIAN A ,  NIELSEN RALPH B ,  MANSKY PAUL ,  MATSIEV LEONID ,  WANG PEI ,  MCFARLAND ERIC

IPC: B01J19/18 ,  B01F13/06 ,  B01F13/08 ,  B01F15/00 ,  B01J19/00 ,  B01J19/26 ,  B01L3/00 ,  B01L7/00 ,  C40B40/14 ,  C40B40/18 ,  F28F27/00 ,  G01K13/00 ,  G01N21/25 ,  G01N35/10 ,  G05B23/02 ,  G05D21/00 ,  B01F7/16

Abstract: An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight.

公开(公告)号：CA2306807C

公开(公告)日：2003-11-25

申请号：CA2306807

申请日：1999-08-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： HAJDUK DAMIAN A ,  NIELSEN RALPH B ,  MCFARLAND ERIC ,  WANG PEI ,  MANSKY PAUL ,  VAN BEEK JOHANNES A M ,  DALES G CAMERON ,  MATSIEV LEONID ,  VAN ERDEN LYNN ,  TURNER HOWARD

IPC: B01J19/18 ,  B01F13/06 ,  B01F13/08 ,  B01F15/00 ,  B01J19/00 ,  B01J19/26 ,  B01L3/00 ,  B01L7/00 ,  C40B40/14 ,  C40B40/18 ,  F28F27/00 ,  G01K13/00 ,  G01N21/25 ,  G01N35/10 ,  G05B23/02 ,  G05D21/00

Abstract: Devices and methods for controlling and monitoring the progress and properti es of multiple reactions are disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injectin g liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for proces s controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight. Computer-based methods are disclosed for process monitoring and control, and for data display and analysis.

公开(公告)号：AT245286T

公开(公告)日：2003-08-15

申请号：AT00928837

申请日：2000-05-05

Applicant: SYMYX TECHNOLOGIES INC

Inventor： RUST WILLIAM C ,  NIELSEN RALPH B

IPC: B01J19/00 ,  C40B50/02 ,  G05B19/042 ,  G05B19/414

公开(公告)号：AU1385402A

公开(公告)日：2002-02-25

申请号：AU1385402

申请日：2001-08-14

Applicant: BASF AG ,  SYMYX TECHNOLOGIES INC

Inventor： HEGER ROBERT ,  SCHROF WOLFGANG ,  SEUFERT MICHAEL ,  AUWETER HELMUT ,  MACHTLE WALTER ,  IDEN RUDIGER ,  HORN DIETER ,  NIELSEN RALPH B ,  CARLSON ERIC ,  CHANG HAN TING ,  KUEBLER SIGRID ,  PETRO MIROSLAV

IPC: B41J2/01 ,  C08F212/04 ,  C08F212/08 ,  C08F220/34 ,  C08F226/06 ,  C09B1/54 ,  C09B67/20 ,  C09B67/46 ,  C09D11/00 ,  C09D11/10 ,  C09D17/00 ,  C09D133/14 ,  C09D135/06 ,  C09D139/08 ,  C09K23/34 ,  C09K23/52 ,  C08F220/00

Abstract: The present invention relates to a set of (co)polymers, dispersion formulations, solid solutions and formulation conditions able to disperse a dye selected from the group of a monoazo dye, quinophthalone dye and an anthraquinone dye in a stable nanoparticular form in an aqueous medium.

公开(公告)号：AU2041200A

公开(公告)日：2000-06-19

申请号：AU2041200

申请日：1999-12-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： FREITAG CHRISTOPHER J ,  HAJDUK DAMIAN ,  NIELSEN RALPH B ,  SAFIR ADAM ,  TIEDE RICHARD

IPC: G01N35/02 ,  B01J4/00 ,  B01J19/00 ,  B01J19/26 ,  C08F2/00 ,  C40B40/14 ,  C40B60/14 ,  G01N35/10

公开(公告)号：AU3742599A

公开(公告)日：1999-10-25

申请号：AU3742599

申请日：1999-04-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： CARLSON ERIC ,  SAFIR ADAM ,  PETRO MIROSLAV ,  NIELSEN RALPH B ,  LEE THOMAS S ,  FRECHET JEAN M J ,  DALES G CAMERON ,  KUEBLER SIGRID C ,  BENNETT JAMES

IPC: G01N37/00 ,  B01D15/08 ,  B01D15/26 ,  B01D15/32 ,  B01D15/34 ,  B01J19/00 ,  B01J19/26 ,  C40B40/14 ,  C40B40/18 ,  G01N1/00 ,  G01N15/02 ,  G01N30/02 ,  G01N30/16 ,  G01N30/24 ,  G01N30/30 ,  G01N30/32 ,  G01N30/46 ,  G01N30/54 ,  G01N30/60 ,  G01N30/88 ,  G01N30/90 ,  G01N33/44 ,  G01N35/08

Abstract: A method and system for researching and developing and/or optimizing new catalysts and products in a combinatorial manner is disclosed. The method begins with starting components or a ligand library and provides methods of creating catalyst or product libraries, which are then tested in a reaction of interest. The system uses methods of robotic handling for moving libraries from station to station. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial catalyst libraries, but also offer significant advantages over conventional experimental methods as well.

公开(公告)号：CA2527935A1

公开(公告)日：1999-10-14

申请号：CA2527935

申请日：1999-04-02

Applicant: SYMYX TECHNOLOGIES INC

Inventor： LEE THOMAS S ,  FRECHET JEAN M J ,  DALES G CAMERON ,  KUEBLER SIGRID C ,  SAFIR ADAM ,  CARLSON ERIC ,  PETRO MIROSLAV ,  BENNETT JAMES ,  NIELSEN RALPH B

IPC: G01N30/54 ,  G01N30/24 ,  G01N30/30 ,  G01N30/36 ,  G01N30/74 ,  G01N35/10

Abstract: A method for characterizing a polymer sample that includes the steps of withdrawing a polymer sample from a sample container into an injection probe of an auto- sampler where the probe is heated to maintain the withdrawn sample at a temperature of not less than about 75 degrees Celsius while resident in the probe. The heated injection probe resides in a first environment maintained at about ambient temperature while withdrawing the polymer sample. The method further includes loading at least a portion of the withdrawn sample into an injection port or a loading port of a liquid chromatography system where the injection port or loading port is adaptable for fluid communication with a chromatographic column. The chromatographic column resides in a heated second environment maintained at a temperature of not less than about 75 degrees Celsius. The loaded sample is injected into a mobile phase of the liquid chromatography system. The sample is maintained at a temperature but not les s than about 75 degrees Celsius during a period of time including from when the sample is withdrawn from the sample container to when the sample is within the heated second environment. The injected sample is chromatographically separated and a property of the sample or a composition thereof is detected.

公开(公告)号：AT323113T

公开(公告)日：2006-04-15

申请号：AT00943377

申请日：2000-07-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： KLAERNER GERRIT ,  NIELSEN RALPH B ,  MANSKY PAUL ,  BENOIT DIDIER ,  CHARMOT DOMINIQUE ,  JANDELEIT BERND ,  MAZZOLA LAURA T

IPC: C08F4/00 ,  C08F220/54 ,  C08F220/58 ,  G01N27/447 ,  G01N33/543 ,  C08F292/00 ,  G01N33/48 ,  C12Q1/68

Abstract: Sensors for determining the presence and concentration of bio-molecules in a biological sample are provided in the form of polymer brushes, which comprise a substrate having a surface that is modified with a water-dispersible or water-soluble polymer segment having functional groups that bind probes. The method of synthesis of such sensors preferably includes use of controlled free radical polymerization techniques, and in particular the use of an iniferter initiator, which allows for controlled architecture polymers to modify the surface of the substrate. In this manner functional groups in the polymer chain are removed from the surface, which allows for solution chemistry to be more realistically reproduced with the benefits of a solid bound probe.

公开(公告)号：DK1069942T3

公开(公告)日：2003-09-29

申请号：DK99942147

申请日：1999-08-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： HAJDUK DAMIAN A ,  DALES G CAMERON ,  VAN ERDEN LYNN ,  NIELSEN RALPH B ,  MANSKY PAUL ,  WANG PEI ,  MCFARLAND ERIC ,  TURNER HOWARD ,  VAN BEEK JOHANNES A M ,  MATSIEV LEONID

IPC: B01F13/06 ,  B01J19/18 ,  B01F13/08 ,  B01F15/00 ,  B01J19/00 ,  B01J19/26 ,  B01L3/00 ,  B01L7/00 ,  C40B40/14 ,  C40B40/18 ,  F28F27/00 ,  G01K13/00 ,  G01N21/25 ,  G01N35/10 ,  G05B23/02 ,  G05D21/00

Abstract: An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight.

公开(公告)号：CA2419376A1

公开(公告)日：2002-02-21

申请号：CA2419376

申请日：2001-08-14

Applicant: SYMYX TECHNOLOGIES INC ,  BASF AG

Inventor： CARLSON ERIC ,  SCHROF WOLFGANG ,  NIELSEN RALPH B ,  AUWETER HELMUT ,  SEUFERT MICHAEL ,  HORN DIETER ,  PETRO MIROSLAV ,  HEGER ROBERT ,  KUEBLER SIGRID ,  MACHTLE WALTER ,  IDEN RUDIGER ,  CHANG HAN TING

IPC: B41J2/01 ,  C08F212/04 ,  C08F212/08 ,  C08F220/34 ,  C08F226/06 ,  C09B1/54 ,  C09B67/20 ,  C09B67/46 ,  C09D11/00 ,  C09D11/10 ,  C09D17/00 ,  C09D133/14 ,  C09D135/06 ,  C09D139/08 ,  C09K23/34 ,  C09K23/52 ,  C08F220/06 ,  C08L25/08 ,  C08L33/14

Abstract: Disclosed are random radical (co)polymers containing -20 to 50 mol% of styre ne as component A, -15 to 35 mol% of acrylic acid as component B, and -15 to 60 mol% of dimethylaminoethylmethacrylate (DMAEM) or 4-vinyl pyridine as component C; and dispersion formulations containing said (co)polymer, a dye selected from the group consisting of a monoazo dye, a quinophtalone dye, an anthraquinone dye, optionally further assistants, and an aqueous system; sol id solutions containing said (co)polmyer, a dye selected from the group consisting of a monoazo dye, a quinophthalone dye, an anthraquinone dye, optionally further assistants; and dyeing formulations and formulations of inks for ink-jets comprising said dispersion formulation and optionally conventional dyeing auxiliaries.