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公开(公告)号：AT534383T
公开(公告)日：2011-12-15
申请号：AT07762162
申请日：2007-05-14
Applicant: VERTEX PHARMA
Inventor： YOUNG CHRISTOPHER , ROWE CHARLES
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公开(公告)号：AU2009282419A2
公开(公告)日：2011-03-31
申请号：AU2009282419
申请日：2009-08-13
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO
IPC: A61K47/32
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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公开(公告)号：ES2718273T5
公开(公告)日：2025-02-06
申请号：ES10708442
申请日：2010-02-18
Applicant: VERTEX PHARMA
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公开(公告)号：LT2464337T
公开(公告)日：2019-05-10
申请号：LT10708442
申请日：2010-02-18
Applicant: VERTEX PHARMA
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公开(公告)号：LT2328618T
公开(公告)日：2018-03-26
申请号：LT09789125
申请日：2009-08-13
Applicant: VERTEX PHARMA
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Patent Agency Ranking
公开(公告)号：EA021706B1
公开(公告)日：2015-08-31
申请号：EA201170330
申请日：2009-08-13
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO
IPC: A61K47/32
Abstract: Изобретениеотноситсяк областифармацевтики, аименнок таблетке, содержащейтвердуюдисперсию N-[2,4-бис-(1,1-диметилэтил)-5-гидроксифенил]-1,4-дигидро-4-оксохинолин-3-карбоксамидаи способуеевведения. Заявленнаятаблеткахарактеризуетсяхорошейрастворимостьюи высокойстабильностью.
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公开(公告)号：HK1161140A1
公开(公告)日：2012-08-24
申请号：HK12102076
申请日：2012-02-29
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO
IPC: A61K20060101
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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公开(公告)号：CA2736545A1
公开(公告)日：2010-04-01
申请号：CA2736545
申请日：2009-09-29
Applicant: VERTEX PHARMA
Inventor： YOUNG CHRISTOPHER
IPC: A61K31/443 , A61P43/00 , C07D405/12
Abstract: The present invention relates to formulations of 3 -(6-(I -(2,2- difluorobenzo[d][l,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2- yl)benzoic acid in Form I, pharmaceutical packs or kits thereof, and methods of treatment therewith.
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公开(公告)号：CA2708146A1
公开(公告)日：2009-06-18
申请号：CA2708146
申请日：2008-12-04
Applicant: VERTEX PHARMA
Inventor： KESHAVARZ-SHOKRI ALI , YOUNG CHRISTOPHER
IPC: A61K31/443 , A61K9/00 , A61K9/10 , A61K31/00 , A61P43/00
Abstract: The present invention relates to formulations of 3-(6-(l-(2,2- difluorobenzo[d] [ 1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid, pharmaceutical packs or kits thereof, and methods of treatment therewith.
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公开(公告)号：MX373230B
公开(公告)日：2025-03-05
申请号：MX2018015847
申请日：2011-02-14
Applicant: VERTEX PHARMA
Inventor： GROSSI ALFREDO , YOUNG CHRISTOPHER , DINEHART KIRK , OVERHOFF KIRK , JACOBUS VERWIJS MARINUS , BOTFIELD MARTYN , HURTER PATRICIA , GROOTENHUIS PETER D J , ROWE WILLIAM
Abstract: La presente invención se refiere a composiciones farmacéuticas que comprenden una dispersión sólida de N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida, a métodos de producción de composiciones farmacéuticas de la presente invención y a métodos de administración de composiciones farmacéuticas de la presente invención.
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