公开(公告)号：EP0535700A2

公开(公告)日：1993-04-07

申请号：EP92116913.2

申请日：1992-10-02

Applicant: THE PERKIN-ELMER CORPORATION

Inventor： Ivaldi, Juan ,  Tracy, David H. ,  Hoult, Robert,c/o Perkin-Elmer Ltd. ,  Spragg, Richard

IPC: G01J3/28

CPC classification number: G01J3/433 ,  G01J3/28 ,  G01N2201/129

Abstract: The multiple linear least squares regression method of determining the concentration of an analyte from a spectrum of an unknown mixture containing the analyte is improved. It is known to combine spectra of individual components of the mixture to derive a model which is then applied to the unknown spectrum. In accordance with this invention, first, and possibly higher, derivatives of the unknown spectrum are also generated and included in the derived model.

Abstract translation: 从包含分析物的未知混合物的光谱确定分析物浓度的多重线性最小二乘回归方法得到改善。 已知将混合物的各个组分的光谱组合以导出随后应用于未知光谱的模型。 根据本发明，还产生未知光谱的第一个，也可能更高的导数，并将其包括在导出的模型中。

公开(公告)号：EP0420135A1

公开(公告)日：1991-04-03

申请号：EP90118365.7

申请日：1990-09-25

Applicant: NIRSYSTEMS INCORPORATED

Inventor： Norris, Carl

IPC: G01J3/06 ,  G01J3/28

CPC classification number: G01J3/2889 ,  G01J3/433 ,  G01J2003/2866 ,  G01J2003/2876 ,  G01N21/4738

Abstract: In a spectrophotometric instrument, a system is provided to correct for distortion caused by rapid scanning of the spectrum. In the instrument, photodetectors (19) detect light energy which is scanned through a spectrum at a rapid rate. An amplifier (20) amplifies the output signal generated by the photodetectors (19). The output signal of the amplifier (20) is sampled at increments and the samples are converted to digital values. A first derivative is determined from the digital values by subtracting from each value the value from the preceding increment. The first derivative values are multiplied times a constant selected to correct for the distortion and the resulting product values are added to the amplitude digital values to provide a set of corrected values representing the intensity detected by the photo­detectors.

Abstract translation: 在分光光度计中，提供了一种系统来校正由于光谱的快速扫描引起的失真。 在仪器中，光电检测器（19）检测以快速扫描频谱的光能。 放大器（20）放大由光检测器（19）产生的输出信号。 放大器（20）的输出信号以增量取样，样本被转换为数字值。 通过从每个值减去前一增量的值，从数字值确定一阶导数。 一阶导数值乘以选定的常数以校正失真，并将所得到的乘积值加到幅度数字值上，以提供一组校正值，这些校正值表示由光电检测器检测到的强度。

公开(公告)号：EP0352923A1

公开(公告)日：1990-01-31

申请号：EP89306879.1

申请日：1989-07-06

Applicant: BAXTER INTERNATIONAL INC. (a Delaware corporation)

Inventor： Cross, Klaus

IPC: A61B5/00 ,  G01N21/31

CPC classification number: A61B5/14551 ,  A61B5/7239 ,  G01J3/433 ,  G01J2003/123 ,  G01J2003/2853 ,  G01J2003/4332 ,  G01N21/31 ,  G01N2021/3144 ,  G01N2201/0826

Abstract: A continuous spectrum of light (10) in a selected wavelength (12) band is transmitted through selected tissue. The spectral distribution of light transmitted through the selected tissue is monitored and differentiated (36) with respect to wavelength. The differentiated spectral data is processed (38) to determine the oxygen saturation in the tissue. The spectral data may be digitized (34) and stored in a storage device (33) that correlates the transmitted intensity with the wavelength. The intensity values for a predetermined number of spectra may be averaged (35) to smooth the spectral data. The first derivative of the averaged spectral data is then determined at predetermined wavelengths and processed (38) with an algorithm to determine the oxygen saturation.

Abstract translation: 所选波长（12）带中的连续光谱（10）被透过选定的组织。 通过选择的组织透射的光的光谱分布被监测并且相对于波长被区分（36）。 处理差分光谱数据（38）以确定组织中的氧饱和度。 频谱数据可以被数字化（34）并存储在存储装置（33）中，其将发送的强度与波长相关联。 可以对预定数量的光谱的强度值进行平均（35）以平滑光谱数据。 然后在预定波长处确定平均光谱数据的一阶导数，并用算法处理（38）以确定氧饱和度。

公开(公告)号：EP0202585A2

公开(公告)日：1986-11-26

申请号：EP86106509.2

申请日：1986-05-13

Applicant: Hellige GmbH

Inventor： Schmidtke, Gerhard, Dr. ,  Hindelang, Fritz, Dr.

IPC: G01J3/433

CPC classification number: G01J3/433 ,  G01J2003/4332

Abstract: Bai einem Derivativ-Spektrometer mit einer Strahlungsquelle (1), einer Meßprobenzelle (4), einem Detektor (6), einer Verstärkeranordnung (7,8) und einer Signalauswerteeinrichtung (10) erfolgt ein Wobbeln der Wellenlänge des die Meßprobenzelle (4) durchquerenden Lichtes mit Hilfe eines taumelnd rotierenden Interferenzfilters (11),

Abstract translation: 在具有辐射源（1），测试样品池（4），检测器（6），放大器系统（7,8）和信号评估装置（10）的衍生光谱仪中，光通过的波长 测试样品池（4）通过以转动方式旋转的干涉滤光器（11）摆动。

公开(公告)号：EP0198021A1

公开(公告)日：1986-10-22

申请号：EP85905179.0

申请日：1985-10-09

Applicant: ANDROS ANALYZERS INCORPORATED

Inventor： WONG, Jacob, Yauman

IPC: G01J3 ,  G01N21

CPC classification number: G01J3/433 ,  G01J2003/4334 ,  G01N21/33

Abstract: Procédé et appareil permettant de détecter la présence d'oxygène élémentaire et d'en déterminer la quantité dans une cellule d'échantillon (15). L'intensité de lumière ultraviolette extrême passant au travers de la cellule d'échantillon (15) avec une bande de longueur d'ondes chevauchant au moins l'une des lignes d'absorption de Shumann-Runge d'oxygène est détectée et comparée avec une condition prédéterminée de non-absorption de la lumière ultraviolette. La condition de non-absorption peut-être obtenue en rétrécissant la bande de longueur d'ondes de sorte que cette bande ne chevauche pas la ligne d'absorption de Shumann-Runge, ou bien elle peut être obtenue en détectant la lumière ultraviolette passant au travers d'une cellule de référence. Est également décrite une nouvelle source de lumière ultraviolette (29) dans laquelle une zone froide capture les atomes neutres du gaz d'émission pour réduire l'effet d'absorption de résonance de la lumière ultraviolette émise par ces atomes neutres.

公开(公告)号：US12085500B2

公开(公告)日：2024-09-10

申请号：US18111740

申请日：2023-02-20

Applicant: Apple Inc.

Inventor： Miikka M. Kangas ,  Mark Alan Arbore ,  David I. Simon ,  Michael J. Bishop ,  James W. Hillendahl ,  Robert Chen

IPC: G01N21/27 ,  G01J3/02 ,  G01J3/32 ,  G01J3/36 ,  G01J3/42 ,  G01J3/433 ,  G01J3/447 ,  G01N21/21 ,  G01N21/35 ,  G01N21/47 ,  G01N21/49

CPC classification number: G01N21/276 ,  G01J3/0286 ,  G01J3/32 ,  G01J3/36 ,  G01J3/42 ,  G01J3/433 ,  G01J3/447 ,  G01N21/35 ,  G01N21/474 ,  G01N21/4785 ,  G01N21/21 ,  G01N2021/4709 ,  G01N2021/4778 ,  G01N21/49 ,  G01N2201/0221 ,  G01N2201/12707 ,  G01N2201/12723

Abstract: This relates to systems and methods for measuring a concentration and type of substance in a sample at a sampling interface. The systems can include a light source, optics, one or more modulators, a reference, a detector, and a controller. The systems and methods disclosed can be capable of accounting for drift originating from the light source, one or more optics, and the detector by sharing one or more components between different measurement light paths. Additionally, the systems can be capable of differentiating between different types of drift and eliminating erroneous measurements due to stray light with the placement of one or more modulators between the light source and the sample or reference. Furthermore, the systems can be capable of detecting the substance along various locations and depths within the sample by mapping a detector pixel and a microoptics to the location and depth in the sample.

公开(公告)号：US20230349761A1

公开(公告)日：2023-11-02

申请号：US18141647

申请日：2023-05-01

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Ian Robert Coddington ,  Nathan Reynolds Newbury ,  Jean-Daniel Deschenes ,  Fabrizio Raphael Giorgetta ,  Esther Baumann

IPC: G01J3/433 ,  G01J3/45 ,  G01J3/02

CPC classification number: G01J3/433 ,  G01J3/45 ,  G01J3/0248 ,  G01J2003/4332 ,  G01J2003/2836

Abstract: Embodiments of the present invention relate to apparatus and methods for dual comb spectroscopy with deterministic stepping and scanning of temporal pulse offset. In one embodiment, the present invention relates to a novel dual-comb spectroscopy including mode locked robust Er-combs and digital phase-locking electronics for step scanning between the two frequency combs and applicable to any phase-locked dual-comb system. The tight phase control of the DCS source allows for the control of temporal offset between the two comb pulses during measurements.

公开(公告)号：US20180149520A1

公开(公告)日：2018-05-31

申请号：US15823421

申请日：2017-11-27

Applicant: CANON KABUSHIKI KAISHA

Inventor： Naoki Kohara

IPC: G01J3/02 ,  H01S3/108 ,  G01J3/44 ,  H01S3/00 ,  G01J3/433 ,  G01N21/65 ,  H01S3/23

CPC classification number: G01J3/0297 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0262 ,  G01J3/433 ,  G01J3/44 ,  G01N21/65 ,  G01N2021/655 ,  G01N2021/656 ,  H01S3/0078 ,  H01S3/1086 ,  H01S3/2391

Abstract: A noise reduction apparatus includes a first delaying/combining unit configured to output first and second pulse light beams, and a second delaying/combining unit configured to branch the first pulse light beam into two pulse light beams to output third and fourth pulse light beams and branch the second pulse light beam into two pulse light beams to output fifth and sixth pulse light beams.

公开(公告)号：US09869633B2

公开(公告)日：2018-01-16

申请号：US15451714

申请日：2017-03-07

Applicant: Daylight Solutions Inc.

Inventor： Benjamin Bird ,  Miles James Weida ,  Jeremy Rowlette

IPC: G01N21/35 ,  G01J3/28 ,  G01J3/10 ,  G01N33/50

CPC classification number: G01N21/35 ,  G01J3/10 ,  G01J3/108 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/433 ,  G01J5/52 ,  G01J2003/104 ,  G01J2003/2826 ,  G01J2003/4332 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/50 ,  G01N2201/12

Abstract: Spectrally analyzing an unknown sample (10A) for the existence of a characteristic includes (i) analyzing a first known sample (10C) having the characteristic and a second known sample (10D) not having the characteristic to identify less than fifty diagnostic spectral features, each diagnostic spectral feature being present at a different diagnostic wavelength in a mid-infrared spectral region; (ii) directing a plurality of interrogation beams (16) at the unknown sample (10A), each of the interrogation beams (16) having a different interrogation wavelength, and each interrogation wavelength corresponding to a different one of the diagnostic wavelengths; (iii) acquiring a plurality of separate output images (245) of the unknown sample (10A), wherein each of the output images (245) is acquired while the unknown sample is illuminated by a different one of the interrogation beams (16); and (iv) analyzing less than fifty output images (245) with a control system (28) to determine whether the characteristic is present in the unknown sample (10A).

公开(公告)号：US09846117B2

公开(公告)日：2017-12-19

申请号：US12814315

申请日：2010-06-11

Applicant: Xin Zhou ,  Xiang Liu ,  Alfred Feitisch

Inventor： Xin Zhou ,  Xiang Liu ,  Alfred Feitisch

IPC: G01J3/433 ,  G01N21/39 ,  G01N21/03 ,  G01N21/05 ,  G01N21/3504 ,  G01N21/27

CPC classification number: G01N21/39 ,  G01J3/433 ,  G01J3/4338 ,  G01J2003/4332 ,  G01J2003/4334 ,  G01N21/031 ,  G01N21/05 ,  G01N21/274 ,  G01N21/3504 ,  G01N2021/354 ,  G01N2021/399

Abstract: Detector data representative of an intensity of light that impinges on a detector after being emitted from a light source and passing through a gas over a path length can be analyzed using a first analysis method to obtain a first calculation of an analyte concentration in the volume of gas and a second analysis method to obtain a second calculation of the analyte concentration. The second calculation can be promoted as the analyte concentration upon determining that the analyte concentration is out of a first target range for the first analysis method.