公开(公告)号：DE19900457A1

公开(公告)日：2000-07-13

申请号：DE19900457

申请日：1999-01-08

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  NGUYEN KIM SON ,  BERNDL GUNTHER ,  SANNER AXEL

IPC: A61K9/16 ,  A61K9/20 ,  A61K9/28

Abstract: The invention relates to a method for producing solid dosage forms by forming a plastic mixture of at least one polymer binding agent, at least one active ingredient and possibly usual additives, which mixture is then shaped. The invention is characterized in that a water-swellable polyurethane having a glass transition temperature Tg >/= 20 DEG C is used as the polymer binding agent.

公开(公告)号：DE19812688A1

公开(公告)日：1999-09-30

申请号：DE19812688

申请日：1998-03-23

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  BERNDL GUNTHER ,  SIMON DIRK ,  SANNER AXEL

IPC: A23L33/00 ,  A61K9/20 ,  A61K9/22 ,  A61K47/32 ,  A61K47/34 ,  C08F279/02 ,  C08L51/04

Abstract: Solid dosage forms contain a water-swellable graft copolymer (I) as binder. An Independent claim is also included for the production of solid dosage forms by mixing (I) with active ingredient(s) and optionally additives, preferably in an extruder, and shaping the resulting plastic mixture.

公开(公告)号：TR9900563T2

公开(公告)日：1999-07-21

申请号：TR9900563

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20

CPC classification number: A61K9/2095 ,  A61K9/2027 ,  A61K9/2086

公开(公告)号：TR199900563T2

公开(公告)日：1999-07-21

申请号：TR9900563

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：NO991527A

公开(公告)日：1999-05-19

申请号：NO991527

申请日：1999-03-29

Applicant: BASF AG

Inventor： NIESSNER MANFRED ,  NILZ CLAUDIA ,  H SSEL PETER ,  KOTHRADE STEPHAN ,  SANNER AXEL

IPC: A61K8/00 ,  A61K8/36 ,  A61K8/42 ,  A61K8/49 ,  A61K8/72 ,  A61K8/81 ,  A61K8/898 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C08F226/02 ,  C08F226/06 ,  A61K7/48

CPC classification number: A61Q5/00 ,  A61K8/817 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  Y10S514/944 ,  Y10S514/945

公开(公告)号：DE59910925D1

公开(公告)日：2004-12-02

申请号：DE59910925

申请日：1999-04-01

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  NEGELE ANTON ,  MEFFERT HELMUT ,  SANNER AXEL

IPC: A61K47/32 ,  A01N25/10 ,  A61K8/72 ,  A61K8/81 ,  C08L39/00 ,  C09K23/00 ,  C09K23/52 ,  B01F17/00

Abstract: A copolymer consisting of the following monomers is used as a solubilizing agent: (a) 5-99 wt.% of at least one N-vinyl carboxamide (I), (b) 1-95 wt.% of at least one monomer with a hydrophobic group, and (c) 0-94 wt.% of at least one other comonomer. A copolymer consisting of the following monomers is used as a solubilizing agent: (a) 5-99 wt.% of at least one N-vinyl carboxamide of formula (I), (b) 1-95 wt.% of at least one monomer with a hydrophobic group, and (c) 0-94 wt.% of at least one other comonomer. R , R = H or 1-6C alkyl. Independent claims are also included for the following: (1) a composition containing at least one water-insoluble ingredient and at least one copolymer as above; (2) use of the copolymer as a protective colloid, especially for stabilizing oil-in-water emulsions.

公开(公告)号：ES2205333T3

公开(公告)日：2004-05-01

申请号：ES98111870

申请日：1998-06-26

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  BLANKENBURG RAINER ,  PETERS IRIS ,  SANNER AXEL

IPC: C08F2/10 ,  C08F2/38 ,  C08F4/28 ,  C08F126/10

Abstract: Production of highly concentrated aqueous solutions of low molecular homopolymers (I) of N-vinylpyrrolidone (NVP) by free radical solution polymerisation in an aqueous medium with hydrogen peroxide (H2O2) as initiator; polymerisation being carried out in the presence of 0.1-30 wt.%, with respect to NVP, of a polymerisation regulator selected from 1-6 carbon (C) alkanols, hydroxylamine salts and water-soluble sulphur compounds.

公开(公告)号：SI0930875T1

公开(公告)日：2003-10-31

申请号：SI9730566

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61K9/20 ,  A61K9/22

公开(公告)号：DE59809260D1

公开(公告)日：2003-09-18

申请号：DE59809260

申请日：1998-06-26

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  BLANKENBURG RAINER ,  PETERS IRIS ,  SANNER AXEL

IPC: C08F2/10 ,  C08F2/38 ,  C08F4/28 ,  C08F126/10

Abstract: Production of highly concentrated aqueous solutions of low molecular homopolymers (I) of N-vinylpyrrolidone (NVP) by free radical solution polymerisation in an aqueous medium with hydrogen peroxide (H2O2) as initiator; polymerisation being carried out in the presence of 0.1-30 wt.%, with respect to NVP, of a polymerisation regulator selected from 1-6 carbon (C) alkanols, hydroxylamine salts and water-soluble sulphur compounds.

公开(公告)号：DE59710059D1

公开(公告)日：2003-06-12

申请号：DE59710059

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.