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公开(公告)号:DE58901297D1
公开(公告)日:1992-06-11
申请号:DE58901297
申请日:1989-02-09
Applicant: BASF AG
Inventor: HOFMANN HANS PETER DR , SEITZ WERNER DR , TREIBER HANS-JOERG DR
IPC: A61K31/275 , A61P9/00 , A61P9/10 , A61P25/28 , A61P43/00 , C07C255/42 , C07C255/50 , C07C255/61
Abstract: Noremopamil and its preparation are described. The substance is suitable for the treatment of disorders.
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公开(公告)号:DE3635931A1
公开(公告)日:1988-04-28
申请号:DE3635931
申请日:1986-10-22
Applicant: BASF AG
Inventor: DAUM LOTHAR DR , EMLING FRANZ DR , KEILHAUER GERHARD DR , SEITZ WERNER DR
IPC: A61K31/275 , A61K31/277 , A61P35/00 , A61K45/05
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公开(公告)号:CS228932B2
公开(公告)日:1984-05-14
申请号:CS405282
申请日:1982-06-01
Applicant: BASF AG
Inventor: SEITZ WERNER DR , SCHEIB KLAUS DR , MICHEL ALFRED
IPC: C07C255/42 , A61K31/275 , C07C20060101 , C07C67/00 , C07C253/00 , C07C255/32 , C07C255/58 , C07C121/66
Abstract: Phenylacetonitriles carrying basic substituents, of the formula I where D, E, F, G, H, I and K have the meanings given in the description, are prepared by reacting the corresponding phenylacetonitrile with a compound of the formula III where X, H, I and K have the meanings given in the description, in a solid/liquid phase system in the presence of a phase transfer catalyst.
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公开(公告)号:DE19632773A1
公开(公告)日:1998-02-19
申请号:DE19632773
申请日:1996-08-14
Applicant: BASF AG
Inventor: MACK HELMUT DR , SEITZ WERNER DR , BAUCKE DORIT DR , LANGE UDO DR , HORNBERGER WILFRIED DR , HOEFFKEN HANS WOLFGANG DR , ZIERKE THOMAS DR
IPC: A61K38/00 , A61K38/05 , A61P7/02 , A61P29/00 , A61P35/00 , A61P35/04 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/078
Abstract: Compounds having formula (I) wherein A, B, E and D have the m eanings indicated in the description, are described, in addition to the production thereof. The substances can be used to combat illnesses.
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25.
公开(公告)号:CZ9701537A3
公开(公告)日:1998-02-18
申请号:CZ153797
申请日:1995-11-25
Applicant: BASF AG
Inventor: BOHM HANS JOACHIM DR , KOSER STEFAN DR , MACK HELMUT DR , PFEIFFER THOMAS DR , SEITZ WERNER DR , HOFFKEN HANS WOLFGANG DR , HORNBERGER WILFRIED DR , ZIERKE THOMAS DR
IPC: A61K38/00 , A61K38/05 , A61P7/02 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/072 , C07K5/087 , A61K38/55
CPC classification number: C07K5/0812 , A61K38/00 , C07K5/06026 , C07K5/06043 , C07K5/06078 , C07K5/06113
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公开(公告)号:DE19502967A1
公开(公告)日:1996-08-01
申请号:DE19502967
申请日:1995-01-31
Applicant: BASF AG
Inventor: KARL ULRICH DR , SEITZ WERNER DR
IPC: C07B57/00 , C07C253/34 , C07C255/43 , C07C253/32
Abstract: A process is disclosed for separating racemates of phenyl acetonitriles having the formula (I), in which R , R , R and n have the meaning given in the description. The process consists in dissolving the racemates (I) in a polar solvent, adding thereto 0.5 to 1.0 mole of optically active camphosulphonic acid per mole of compound (I), heating the mixture up to 40 to 100 DEG C, letting it cool down and extracting the optically active phenyl acetonitrile (I) from the thus obtained salt.
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公开(公告)号:ES2054650T3
公开(公告)日:1994-08-16
申请号:ES87117946
申请日:1987-12-04
Applicant: BASF AG
Inventor: SEITZ WERNER DR , UNGER LILIANE DR , RASCHACK MANFRED DR , BALDINGER VERENA DR , RUEBSAMEN KLAUS DR , GRIES JOSEF DR
IPC: A61K31/275 , A61K31/335 , A61K31/357 , A61K31/36 , A61P1/04 , A61P3/00 , A61P9/00 , A61P11/00 , A61P43/00 , C07C67/00 , C07C253/00 , C07C253/30 , C07C255/32 , C07C255/33 , C07C255/35 , C07C255/37 , C07C255/42 , C07C255/53 , C07C255/58 , C07D317/50 , C07D317/60 , C07D319/08 , C07D319/18 , C07D321/00
Abstract: Basic-substituted phenylacetonitriles of the formula I … … in which… R to R and n have the meaning given in the description, are suitable for combating diseases.
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公开(公告)号:ES2051721T3
公开(公告)日:1994-07-01
申请号:ES87115378
申请日:1987-10-21
Applicant: BASF AG
Inventor: SEITZ WERNER DR , DAUM LOTHAR DR , EMLING FRANZ DR , KEILHAUER GERHARD DR
IPC: A61K31/275 , A61K31/277 , A61P35/00
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公开(公告)号:AT79255T
公开(公告)日:1992-08-15
申请号:AT87115378
申请日:1987-10-21
Applicant: BASF AG
Inventor: SEITZ WERNER DR , DAUM LOTHAR DR , EMLING FRANZ DR , KEILHAUER GERHARD DR
IPC: A61K31/275 , A61K31/277 , A61P35/00
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公开(公告)号:DE3603032A1
公开(公告)日:1987-08-06
申请号:DE3603032
申请日:1986-01-31
Applicant: BASF AG
Inventor: UNGER LILIANE DR , RASCHACK MANFRED DR , BALDINGER VERENA DR , DENGEL FERDINAND DR , EHRMANN OSKAR DR , TREIBER HANS-JOERG DR , SEITZ WERNER DR
IPC: A61K31/275 , A61K31/335 , A61K31/357 , A61P7/02 , A61P9/00 , A61P9/12 , A61P43/00 , C07C67/00 , C07C253/00 , C07C255/32 , C07C255/42 , C07C255/43 , C07C255/53 , C07C255/58 , C07D317/58 , C07D319/08 , C07D319/18 , C07D321/12 , C07D325/00 , C07C121/66 , C07C121/75 , C07D317/50 , C07D317/52 , C07D317/62 , C07D317/64
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