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公开(公告)号:CA1282338C
公开(公告)日:1991-04-02
申请号:CA540065
申请日:1987-06-18
Applicant: KAO CORP
Inventor: KITAHARA TAKASHI , YOSHIDA EISAKU , AKATSU MITSUHIRO , JOKURA YOJI , HATTORI MICHIHIRO , TAKAISHI NAOTAKE
IPC: A61K8/00 , A61K8/97 , A61K36/00 , A61K36/18 , A61K36/52 , A61P35/00 , A61P43/00 , A61Q5/00 , A61Q7/00 , A61Q7/02 , A61Q15/00 , A61K35/78
Abstract: Disclosed is a 5.alpha.-reductase inhibitor comprising as an effective component an extract from leaves and/or pericarps of a walnut. The inhibitor exhibits highly potent 5.alpha.-reductase inhibiting activity and high safety, and is thus effective in curing and preventing diseases caused by testosterone, e.g. male-pattern alopecia, hirsutism, prostate cancer and the like.
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公开(公告)号:ES2012045B3
公开(公告)日:1990-03-01
申请号:ES86117200
申请日:1986-12-10
Applicant: KAO CORP
Inventor: KAWAMATA AKIRA , YANO SHINJI , HATTORI MICHIHIRO , AKAZAKI SHUICHI , IMOKAWA GENJI , TAKAISHI NAOTAKE
IPC: A61K8/30 , A61K8/00 , A61K8/42 , A61K8/68 , A61K31/16 , A61P17/00 , A61Q19/00 , C07C67/00 , C07C231/00 , C07C233/18 , C07C233/20 , C09K23/22 , F16K31/18
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公开(公告)号:GB2213723A
公开(公告)日:1989-08-23
申请号:GB8905357
申请日:1989-03-09
Applicant: KAO CORP
Inventor: HATTORI MICHIHIRO , AKAZAKI SHUICHI , YOSHIZUKA NAONOBU , IMOKAWA GENJI
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公开(公告)号:FR2574399B1
公开(公告)日:1989-05-05
申请号:FR8518341
申请日:1985-12-11
Applicant: KAO CORP
Inventor: NAKAMURA KOICHI , HORI KIMIHIKO , HATTORI MICHIHIRO , TEJIMA TORU , IMOKAWA GENJI , TAKAISHI NAOTAKE
IPC: C07C65/32 , A61K8/368 , A61Q17/04 , C07C51/00 , C07C51/373 , C07C65/40 , C07C67/00 , C07C51/083 , A61K7/44
Abstract: 4-methoxy-2'-carboxydibenzoylmethane of the following general formula (I) (I) is prepared by reacting p-methoxyacetophenone (III) with phthalic anhydride (II) in accordance with the following reaction equation. +TR The compound (I) and its salts absorb both UV-A and UV-B, and exhibit prominent effects as a ultraviolet absorber for cosmetic formulations such as skin cosmetic formulations and hair cosmetic formulations.
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公开(公告)号:CH665205A5
公开(公告)日:1988-04-29
申请号:CH526985
申请日:1985-12-10
Applicant: KAO CORP
Inventor: NAKAMURA KOICHI , HORI KIMIHIKO , HATTORI MICHIHIRO , TEJIMA TORU , IMOKAWA GENJI , TAKAISHI NAOTAKE
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公开(公告)号:FR2555167B1
公开(公告)日:1987-07-24
申请号:FR8417487
申请日:1984-11-16
Applicant: KAO CORP
Inventor: TEJIMA TOHRU , NAKAMURA KOICHI , HATTORI MICHIHIRO , MASUDA SHINICHI , IMOKAWA GENJI , TAKAISHI NAOTAKE
IPC: C07C69/28 , A61K8/00 , A61K8/33 , A61K8/37 , A61K31/235 , A61Q17/04 , C07C69/017 , C07C69/035 , C07C69/24 , C07C69/527 , C07C69/533 , C09K3/00 , A61K7/42
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公开(公告)号:GB2149789B
公开(公告)日:1987-05-07
申请号:GB8427998
申请日:1984-11-06
Applicant: KAO CORP
Inventor: TEJIMA TOHRU , NAKAMURA KOICHI , HATTORI MICHIHIRO , MASUDA SHINICHI , IMOKAWA GENJI , TAKAISHA NAOTAKE
IPC: C07C69/28 , A61K8/00 , A61K8/33 , A61K8/37 , A61K31/235 , A61Q17/04 , C07C69/017 , C07C69/035 , C07C69/24 , C07C69/527 , C07C69/533 , C09K3/00 , A61K7/42
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公开(公告)号:FR2574399A1
公开(公告)日:1986-06-13
申请号:FR8518341
申请日:1985-12-11
Applicant: KAO CORP
Inventor: NAKAMURA KOICHI , HORI KIMIHIKO , HATTORI MICHIHIRO , TEJIMA TORU , IMOKAWA GENJI , TAKAISHI NAOTAKE
IPC: C07C65/32 , A61K8/368 , A61Q17/04 , C07C51/00 , C07C51/373 , C07C65/40 , C07C67/00 , C07C51/083 , A61K7/44
Abstract: 4-methoxy-2'-carboxydibenzoylmethane of the following general formula (I) (I) is prepared by reacting p-methoxyacetophenone (III) with phthalic anhydride (II) in accordance with the following reaction equation. +TR The compound (I) and its salts absorb both UV-A and UV-B, and exhibit prominent effects as a ultraviolet absorber for cosmetic formulations such as skin cosmetic formulations and hair cosmetic formulations.
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公开(公告)号:JPS61213280A
公开(公告)日:1986-09-22
申请号:JP5702685
申请日:1985-03-20
Applicant: KAO CORP
Inventor: HOTTA HAJIME , TEJIMA SUSUMU , NAKAMURA KOICHI , HATTORI MICHIHIRO
IPC: A61K8/00 , A61K8/26 , A61K8/33 , A61K8/36 , A61K8/368 , A61K8/37 , A61K8/39 , A61Q1/00 , A61Q1/12 , A61Q17/04 , C09K3/00
Abstract: PURPOSE:An ultraviolet ray absorber preventing effectively ultraviolet rays in the whole wave length, protecting the skin from sunburn, having stability to light rays and heat with day, containing a specific dibenzoylmethane and a hydrous oxide of a polyvalent metal. CONSTITUTION:The aimed substance containing (A) a dibenzoylmethane derivative (e.g., sodium 3'-hydroxy-4'-methoxybenzoylmethane-2-carboxylate, etc.) shown by the formula I (X is H, monovalent metallic cation, organic cation, 1-24C aliphatic hydrocarbon, or 2-3C polyoxyalkylene oxide; nY and mZ are OH, 1-24C aliphatic hydrocarbon, 1-24C alkoxy, or 2-3C polyoxyalkylene oxide; m and n are 0-3), and (B) a hydrous oxide of a polyvalent metallic element [e.g., alpha-alumina-hydrate(Al2O3-H2O), etc.]. The component A, for example, is obtained by condensing a monoester shown by the formula II (R is methyl, or ethyl) with a substituted acetophenone shown by the formula III.
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公开(公告)号:JP2004326708A
公开(公告)日:2004-11-18
申请号:JP2003124493
申请日:2003-04-28
Applicant: Dentsu Research Inc , Kao Corp , 株式会社電通リサーチ , 花王株式会社
Inventor: KONDO MIYUKI , HATTORI MICHIHIRO , NAKAJI YOSHIYO , TAKEDA MASAKI
Abstract: PROBLEM TO BE SOLVED: To provide an analysis technique of "consumer value model" based on "post-modern approach" and analyze and judge concepts of values of a consumer for all of matters for which the consumer finds some values. SOLUTION: The analysis method of consumer values comprises allocating a first value axis (purpose and means), a second value axis (self reference and other reference) and a third value axis (active and passive) which are each based on an opposed concept to x-axis, y-axis and z-axis in the three-dimensional space; arranging a cube having ridgelines on the value axes; allocating, to each apex of the cube, total 8 consumer values which constitutes 12 pairs (convenience, quality, impression, possession, pleasure, aesthetic appreciation, rule and mood); asking questions on value trend of subjects for each of 12 pairs of consumer values; summing up the responses to the questions; and displaying a value pattern of the consumer in a system of 8 consumer values. COPYRIGHT: (C)2005,JPO&NCIPI
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