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    Polymer coatings containing drug powder of controlled morphology
    22.
    发明专利
    Polymer coatings containing drug powder of controlled morphology 未知

    公开(公告)号：AU2006270221B2

    公开(公告)日：2012-01-19

    申请号：AU2006270221

    申请日：2006-07-14

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： TAYLOR DOUG ,  COLE MIKE ,  DEYOUNG JAMES ,  MCCLAIN JIM ,  SMOKE CLINT

    IPC: B05D3/00 ,  A61L2/00

    Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.

    POLYMER COATINGS CONTAINING DRUG POWDER OF CONTROLLED MORPHOLOGY
    23.
    发明专利
    POLYMER COATINGS CONTAINING DRUG POWDER OF CONTROLLED MORPHOLOGY 未知

    公开(公告)号：CA2615452A1

    公开(公告)日：2007-01-25

    申请号：CA2615452

    申请日：2006-07-14

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： MCCLAIN JAMES B ,  SMOKE CLINT ,  TAYLOR DOUG ,  COLE MIKE ,  DEYOUNG JAMES

    IPC: B05D3/00 ,  A61L2/00

    Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.

    Method of coating microelectronic substrates
    24.
    发明专利
    Method of coating microelectronic substrates 未知

    公开(公告)号：AU2003294557A8

    公开(公告)日：2004-08-30

    申请号：AU2003294557

    申请日：2003-12-02

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： TAYLOR DOUG ,  WAGNER MARK I ,  MCCLAIN JAMES B ,  GROSS STEPHEN M ,  BRAINARD DAVID E ,  DEYOUNG JAMES P

    IPC: B05D1/18 ,  H01L21/00 ,  H01L21/02 ,  H01L21/285 ,  H01L21/288 ,  B05D1/00

    Abstract: A method of coating a substrate comprises the steps of: (a) providing a substrate in an enclosed vessel, the substrate having a surface portion; (b) at least partially filling the enclosed vessel with a first supercritical fluid so that said first supercritical fluid contacts the surface portion, with the first supercritical fluid carrying or containing a coating component; then (c) adding a separate compressed gas atmosphere to the reaction vessel so that a boundary is formed between the first supercritical fluid and the separate compressed gas atmosphere, said separate compressed gas atmosphere having a density less than said first supercritical fluid; and then (d) displacing said first supercritical fluid from said vessel by continuing adding said separate compressed gas atmosphere to said vessel so that said boundary moves across said surface portion and a thin film of coating component is deposited on said microelectronic substrate.

    METHOD OF COATING MICROELECTRONIC SUBSTRATES
    26.
    发明申请
    METHOD OF COATING MICROELECTRONIC SUBSTRATES 审中-公开
    涂覆微电子基片的方法

    公开(公告)号：WO2004070071A3

    公开(公告)日：2004-11-11

    申请号：PCT/US0338324

    申请日：2003-12-02

    Applicant: MICELL TECHNOLOGIES INC ,  DEYOUNG JAMES P ,  MCCLAIN JAMES B ,  GROSS STEPHEN M ,  TAYLOR DOUG ,  WAGNER MARK I ,  BRAINARD DAVID E

    Inventor： DEYOUNG JAMES P ,  MCCLAIN JAMES B ,  GROSS STEPHEN M ,  TAYLOR DOUG ,  WAGNER MARK I ,  BRAINARD DAVID E

    IPC: B05D1/18 ,  H01L21/00 ,  H01L21/02 ,  H01L21/285 ,  H01L21/288 ,  B05D1/00

    CPC classification number: H01L21/283 ,  B05D1/18 ,  B05D2401/90 ,  H01L21/28556 ,  H01L21/288 ,  H01L21/67028 ,  H01L28/65

    Abstract: A method of coating a substrate comprises the steps of: (a) providing a substrate in an enclosed vessel, the substrate having a surface portion; (b) at least partially filling the enclosed vessel with a first supercritical fluid so that said first supercritical fluid contacts the surface portion, with the first supercritical fluid carrying or containing a coating component; then (c) adding a separate compressed gas atmosphere to the reaction vessel so that a boundary is formed between the first supercritical fluid and the separate compressed gas atmosphere, said separate compressed gas atmosphere having a density less than said first supercritical fluid; and then (d) displacing said first supercritical fluid from said vessel by continuing adding said separate compressed gas atmosphere to said vessel so that said boundary moves across said surface portion and a thin film of coating component is deposited on said microelectronic substrate.

    Abstract translation: 一种涂布基材的方法包括以下步骤：（a）在封闭容器中提供基材，基材具有表面部分; （b）用第一超临界流体至少部分地填充封闭容器，使得所述第一超临界流体接触表面部分，第一超临界流体携带或含有涂层组分; 然后（c）将单独的压缩气体气氛添加到反应容器中，使得在第一超临界流体和单独的压缩气体气氛之间形成边界，所述单独的压缩气体气氛的密度小于所述第一超临界流体的密度; 然后（d）通过继续将所述分开的压缩气体气氛加入所述容器，使所述边界移过所述表面部分，并将涂层组分的薄膜沉积在所述微电子基底上，从所述容器中置换所述第一超临界流体。

    STENT WITH POLYMER COATING CONTAINING AMORPHOUS RAPAMYCIN
    28.
    发明申请
    STENT WITH POLYMER COATING CONTAINING AMORPHOUS RAPAMYCIN 审中-公开
    含非晶形RAPAMYCIN的聚合物涂层支架

    公开(公告)号：WO2007011708A8

    公开(公告)日：2007-04-26

    申请号：PCT/US2006027322

    申请日：2006-07-14

    Applicant: MICELL TECHNOLOGIES INC ,  TAYLOR DOUG ,  DAYOUNG JAMES ,  MCCLAIN JIM

    Inventor： TAYLOR DOUG ,  DAYOUNG JAMES ,  MCCLAIN JIM

    IPC: A61F2/02

    CPC classification number: A61F2/86 ,  A61F2/07 ,  A61F2002/821 ,  A61F2240/002 ,  A61F2250/0067 ,  A61L31/022 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/216 ,  A61L2300/606 ,  A61L2420/08

    Abstract: A coated coronary stent, comprising: a stainless steel sent framework coated with a primer layer of Parylene C; and a rapamycin-polyrner coating having substantially uniform thickness disposed on the stent framework, wherein the rapamycin-polymer coating comprises polybutyl methacrylate (PBMA), polyethylene-co-vinyl acetate (PEVA) and rapamycin, wherein substantially all of the rapamycin in the coating is in amorphous form and substantially uniformly dispersed within the rapamycin-polymer coating.

    Abstract translation: 一种带涂层的冠状动脉支架，包括：涂有聚对二甲苯C的底层的不锈钢发送框架; 和布置在支架框架上的具有基本均匀厚度的雷帕霉素聚合物涂层，其中雷帕霉素聚合物涂层包含聚甲基丙烯酸丁酯（PBMA），聚乙烯 - 共聚乙酸乙烯酯（PEVA）和雷帕霉素，其中涂层中基本上所有的雷帕霉素 呈无定形形式且基本均匀地分散在雷帕霉素聚合物涂层内。

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