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公开(公告)号：KR1020110060689A
公开(公告)日：2011-06-08
申请号：KR1020090117350
申请日：2009-11-30
Applicant: (주)아모레퍼시픽
IPC: A61K31/327 , A61K31/10 , A61K31/70 , A61P17/10
Abstract: PURPOSE: A composition for preventing or treating acne is provided to ensure high stability and excellent usability. CONSTITUTION: A composition for preventing or treating acne contains 0.001-50 weight% of benzoyl peroxide, derivative thereof, hydrous form, or pharmaceutically salt thereof; 0.001-50 weight% of clindamycin, derivative thereof, hydrous form, or pharmaceutically acceptable salt thereof; and 0.01-10 weight% of sodium pyrosulfite.
Abstract translation: 目的：提供一种预防或治疗痤疮的组合物，以确保高稳定性和优异的使用性。 构成：用于预防或治疗痤疮的组合物含有0.001-50重量％的过氧化苯甲酰，其衍生物，含水形式或其药学上的盐; 克林霉素0.001-50重量％，其衍生物，含水形式或其药学上可接受的盐; 和0.01-10重量％的焦亚硫酸钠。
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公开(公告)号：KR1020110017687A
公开(公告)日：2011-02-22
申请号：KR1020090075280
申请日：2009-08-14
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A23L33/10 , A23L33/105 , A61K36/75 , A61Q19/02
Abstract: PURPOSE: A composition containing Phellodendri Cortex extract is provided to suppress acne pigmentation in a cosmetic, food, or medical field. CONSTITUTION: A composition for suppressing pigmentation by acne contains 0.5-20 weight% of Phellodendri Cortex extract as an active ingredient. An external use skin composition contains the composition for suppressing pigmentation. The composition is a cosmetic formulation. A composition for aftercare of acne contains Phellodendri Cortex extract as an active ingredient. A food additive or health food composition contains the composition for suppressing pigmentation or aftercare.
Abstract translation: 目的：提供含有黄柏提取物的组合物，以抑制化妆品，食品或医疗领域的痤疮色素沉着。 构成：用于抑制痤疮色素沉着的组合物含有0.5-20重量％的黄柏提取物作为活性成分。 外用皮肤组合物含有抑制色素沉着的组合物。 组合物是化妆品制剂。 用于治疗痤疮的组合物含有黄柏提取物作为活性成分。 食品添加剂或保健食品组合物含有抑制色素沉着或后期保养的组合物。
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公开(公告)号：KR1020110017565A
公开(公告)日：2011-02-22
申请号：KR1020090075084
申请日：2009-08-14
Applicant: (주)아모레퍼시픽
IPC: A61K8/97 , A61Q19/02 , A23L1/30 , A61K36/484
CPC classification number: A61K8/97 , A23L33/10 , A61K36/484 , A61Q19/02
Abstract: PURPOSE: A composition containing Glycyrrhiza Uralensis Fischer extract is provided to suppress pigmentation and/or scar by acne and to be used in cosmetic or medical field. CONSTITUTION: A composition for suppressing pigmentation or scar by acne contains Glycyrrhiza Uralensis Fischer extract as an active ingredient. The Glycyrrhiza Uralensis Fischer extract suppresses gelatinase. An external use composition contains the composition for suppressing pigmentation or scar. The composition is a cosmetic formulation. An aftercare composition for acne sequel contains Glycyrrhiza Uralensis Fischer extract as an active ingredient.
Abstract translation: 目的：提供含有甘草红素Fischer提取物的组合物，以抑制痤疮的色素沉着和/或疤痕，并用于化妆品或医疗领域。 构成：用于抑制痤疮色素沉着或疤痕的组合物含有甘草甘草提取物作为活性成分。 甘草甘草提取物抑制明胶酶。 外用组合物含有抑制色素沉着或瘢痕的组合物。 组合物是化妆品制剂。 痤疮后遗症的保健用组合物含有甘草作为活性成分提取物。
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公开(公告)号：KR1020110017564A
公开(公告)日：2011-02-22
申请号：KR1020090075083
申请日：2009-08-14
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing Saururus chinensis extract is provided to suppress pigmentation and/or scar. CONSTITUTION: A composition for preventing pigmentation or scar by acne contains 0.5-2.0 weight% of Saururus chinensis extract. An external use skin composition contains the composition for preventing pigmentation or scar by acne. The composition is a cosmetic formulation. A food additive or health food composition contains the composition for preventing pigmentation or scar or after care composition.
Abstract translation: 目的：提供含有Saururus chinensis提取物的组合物以抑制色素沉着和/或疤痕。 构成：用于预防痤疮色素沉着或疤痕的组合物含有0.5-2.0重量％的中华黄芪提取物。 外用皮肤组合物含有防止色素沉着或痤疮瘢痕的组合物。 组合物是化妆品制剂。 食品添加剂或保健食品组合物含有用于防止色素沉着或瘢痕或护理组合物的组合物。
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公开(公告)号：KR1020100026855A
公开(公告)日：2010-03-10
申请号：KR1020080086021
申请日：2008-09-01
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/82 , A61K36/21 , A61K36/232 , A61K36/234 , A61K36/48 , Y10S514/844 , Y10S514/857 , Y10S514/886
Abstract: PURPOSE: A skin external composition for preventing or treating inflammatory dermatitis containing natural products is provided to ensure anti-inflammation and skin moisturization. CONSTITUTION: A skin external composition for preventing or treating inflammatory dermatitis contains 0.001-20 weight% of green tea, 0.05-3 weight% of sophora root, 0.05-3 weight% of Portulaca oleracea L., and 0.5-30 weight% of Polygonatum officinale as active ingredient. The skin external composition additionally contains 1-50 weight% of starch, 1-10 weight% of cacao bean, 1-10 weight% of Cnidii Rhizoma or 0.5-5 weight% of Angelicae gigantis Radix. The composition is cosmetic composition or pharmaceutical composition.
Abstract translation: 目的：提供用于预防或治疗含有天然产物的炎性皮炎的皮肤外用组合物，以确保抗炎和皮肤保湿。 构成：用于预防或治疗炎症性皮炎的皮肤外用组合物含有绿茶的重量百分比为0.001-20重量％，槐根0.05-3重量％，马齿苋属0.05-3重量％，黄芪0.5-30重量％ 草药作为活性成分。 皮肤外用组合物另外含有1-50重量％的淀粉，1-10重量％的可可豆，1-10重量％的Cnidii Rhizoma或0.5-5重量％的Angelicae gigantis大戟。 组合物是化妆品组合物或药物组合物。
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Patent Agency Ranking
公开(公告)号：KR1020100011226A
公开(公告)日：2010-02-03
申请号：KR1020080072355
申请日：2008-07-24
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A multilayer lamella granule and a skin external composition containing the same are provided to stably maintain lamella structure which is similar to the skin keratin layer and ensure moisturization effect and barrier healing effect. CONSTITUTION: A multilayer lamella granule contains nucleant, lipid lamella layer containing ceramide on the nucleant, and polymer layer on the lipid lamella layer. The nucleant is sugar, salt, hyaluronic acid, alginic acid, chondroitin sulfate, chitosan, chitin, polylysine, collagen, gelatin, stearic acid, cetyl alcohol, stearyl alcohol or their mixture. The ceramide is a natural ceramide 1-8 or similar ceramide of chemical formulas 1-6. A similar keratin lipid lamella layer is contained in 0.000001-99 weight% based on total weight. The similar keratin lipid lamella layer additionally contains fatty acid, cholesterol or its derivative or their mixture. The fatty acid is saturated or unsaturated fatty acid of 8-30 carbon atoms.
Abstract translation: 目的：提供多层薄片颗粒和含有它的皮肤外用组合物，以稳定地保持与皮肤角质层相似的薄片结构，并确保保湿效果和屏障愈合效果。 构成：多层薄片颗粒含有成核剂，成核剂上含有神经酰胺的脂质层层和脂质层层上的聚合物层。 成核剂是糖，盐，透明质酸，海藻酸，硫酸软骨素，壳聚糖，壳多糖，聚赖氨酸，胶原，明胶，硬脂酸，鲸蜡醇，硬脂醇或它们的混合物。 神经酰胺是天然神经酰胺1-8或类似化学式1-6的神经酰胺。 基于总重量，类似的角蛋白脂质层层含量为0.000001-99重量％。 类似的角蛋白脂质层层还含有脂肪酸，胆固醇或其衍生物或其混合物。 脂肪酸是8-30个碳原子的饱和或不饱和脂肪酸。
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37.发明公开
公开(公告)号：KR1020080097420A
公开(公告)日：2008-11-05
申请号：KR1020087019182
申请日：2007-02-14
Applicant: (주)아모레퍼시픽
IPC: A61K31/17 , A61K31/765 , A61P17/00
CPC classification number: A61K9/0014 , A61K31/17 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/26 , A61K47/32
Abstract: A composition for external application for treating and preventing the pruritus or irritant skin disease is provided to have excellent fluxes and stability by containing the thiourea derivative and to be useful in pruritus or irritant skin disease. A composition for external application of O/w-shaped emulsion form comprises (1) drug expressed as a compound of a chemical formula 1, (2) a component selected from a group consisting of squalene, dimethicone, propylene glycol, butylene glycol and mineral oil, (3) a component selected from a group consisting of polyethylene glycol 400, polyoxyethylene alkyl ether, cetyl alcohol and solbitan stearate, (4) water and (5) a component selected from a group consisting of ethanol, twin 60, carbomer 940, EDTA.2Na and triethanolammine.
Abstract translation: 提供用于治疗和预防瘙痒或刺激性皮肤病的外用组合物，通过含有硫脲衍生物具有优异的通量和稳定性，并且可用于瘙痒或刺激性皮肤病。 用于外用O / W型乳液形式的组合物包括（1）以化学式1化合物表示的药物，（2）选自角鲨烯，聚二甲基硅氧烷，丙二醇，丁二醇和矿物质的组分 油，（3）选自聚乙二醇400，聚氧乙烯烷基醚，鲸蜡醇和硬脂酸solbitan的组分，（4）水和（5）选自乙醇，双螺杆菌60，卡波姆940 ，EDTA.2Na和三乙醇胺。
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38.发明授权2,2-디메틸-3-알킬에테르-4-알콕시-6-알킬 아미노벤조피란 유도체를 유효성분으로 함유하는 PGE2 활성에 관련된 염증질환 치료제 有权由含有作为有效成分的2,2-二甲基-3-烷基-4-羟基-6-烷基氨基苯甲酰基衍生物的PGE2活性诱导的抗炎性疾病治疗剂
公开(公告)号：KR100673974B1
公开(公告)日：2007-01-24
申请号：KR1020050045294
申请日：2005-05-28
Inventor： 공영대 , 이일영 , 이종철 , 조희영 , 황종연 , 최형섭 , 전현숙 , 유성은 , 이창훈 , 성대석 , 김광미 , 김대권 , 양혜진 , 김형준 , 박종희 , 심영철
IPC: C07D311/22 , C07D311/24
CPC classification number: C07D311/22
Abstract: 본 발명은 하기 화학식 1로 표시되는 2,2-디메틸-3-알킬에테르-4-알콕시-6-알킬 아미노벤조피란 유도체, 약제학적으로 허용 가능한 그의 염 및 그를 유효성분으로 함유하는 프로스타그란딘 E2(prostagrandine E2 ; PGE2)의 생성 억제활성 및 그로 인한 용도에 관한 것이다.
본 발명의 2,2-디메틸-3-알킬에테르-4-알콕시-6-알킬 아미노벤조피란 유도체는 PGE2의 생성에 대하여 우수한 억제활성을 나타냄을 세포 수준 및 동물실험을 통하여 규명함으로써, 상기 2,2-디메틸-3-알킬에테르-4-알콕시-6-알킬 아미노벤조피란 유도체 또는 약제학적으로 허용 가능한 그의 염을 유효성분으로 함유하여 PGE2 활성으로 유발되는 염증관련 질환 치료제 개발에 유용하다.
(상기 식에서, R
1 , R
2 , 및 R
3 는 명세서에서 정의한 바와 같다.)
아미노벤조피란, 프로스타그란딘, 산화적스트레스, 라디칼, 염증치료제-
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公开(公告)号：KR100879411B1
公开(公告)日：2009-01-19
申请号：KR1020060065840
申请日：2006-07-13
Applicant: (주)아모레퍼시픽 , 에스비사이언스(주)
IPC: A61K31/131 , A61P17/02
Abstract: 본 발명은 하기 화학식 1로 표시되는 2-아미노-2-옥틸옥시메틸-프로판-1,3-디올(2-amino-2-octyloxymethyl-propane-1,3-diol, AOOMP) 또는 이의 약학적으로 허용 가능한 염을 포함하는, 스핑고실포스포릴콜린(sphingosylphosphorylcholine, SPC)의 작용을 억제하는 약학 조성물에 관한 것이다.
본 발명에 따른 약학 조성물은 SPC의 생체내 및 생체외 작용에 따른 세포 분열 증식, 염증 반응, 히스타민 분비 또는 가려움증 등을 효과적으로 억제하고, 투여시 심장 박동수의 저하와 같은 부작용이 없으므로, 외상 후의 흉터 형성 억제 및 아토피성 피부염 또는 기타 질환에서 나타나는 염증, 소양증, 및 피부 감염증 등의 예방 및 치료에 유용하게 사용될 수 있다.
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