公开(公告)号：CA1105023A

公开(公告)日：1981-07-14

申请号：CA305369

申请日：1978-06-13

Applicant: BASF AG

Inventor： BINNIG FRITZ ,  FRIEDRICH LUDWIG ,  HOFMANN HANS P ,  KREISKOTT HORST ,  MUELLER CLAUS ,  RASCHACK MANFRED

IPC: A61K31/435 ,  A61K31/445 ,  A61P9/06 ,  C07D221/00 ,  C07D471/08

Abstract: This invention relates to bispidine derivatives of the formula where R1 is H or C6H5, R2 is H, Cl or CF3, R3 is H, F or Cl and X is 0 or 1, with the proviso that R1, R2 and R3 cannot all be H when X is 0. The compounds are prepared by condensing N-monobenzylbispidine with appropriately substituted phenylethyl halides or by a Mannich reaction of N-benzyl-piperid-4-one with appropriately substituted phenylalkylamines, followed by redustion. They exhibit mainly anto-arrhythmic action.

公开(公告)号：FI780915A

公开(公告)日：1978-10-03

申请号：FI780915

申请日：1978-03-23

Applicant: BASF AG

Inventor： ALBRECHT HANS PETER ,  FRIEDRICH LUDWIG ,  ZIMMERMANN FRANK

IPC: C07H15/26 ,  A61K31/522 ,  A61K31/70 ,  A61K31/7028 ,  A61P3/06 ,  C07D473/08 ,  C07H7/06 ,  C07H9/04 ,  C07H13/10 ,  C07H

公开(公告)号：MX9203501A

公开(公告)日：1992-09-01

申请号：MX9203501

申请日：1992-06-26

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETZSCHMAR ROLF ,  LEHMANN HANS DIETER ,  FRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18 ,  A61K31/33

公开(公告)号：FI76083C

公开(公告)日：1988-09-09

申请号：FI821141

申请日：1982-04-01

Applicant: BASF AG

Inventor： STEINER GERD ,  FRIEDRICH LUDWIG ,  LENKE DIETER

IPC: A61K31/00 ,  A61K31/55 ,  A61P1/04 ,  C07D223/20 ,  C07D401/06 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D413/12 ,  C07F9/59

公开(公告)号：CA1215365A

公开(公告)日：1986-12-16

申请号：CA415118

申请日：1982-11-08

Applicant: BASF AG

Inventor： SCHLECKER RAINER ,  FRIEDRICH LUDWIG ,  LENKE DIETER

IPC: A61K31/505 ,  A61P37/08 ,  C07D239/95 ,  C07D487/04 ,  C07D491/04 ,  C07D491/14 ,  C07D491/147 ,  C07D491/056

Abstract: 0050/35590 1,2,4-Triazolo¢1,5-c!-quinazolinones of the general formula I (I) and their pharmaceutically tolerated salts, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful drugs in the treatment of allergic disorders.

公开(公告)号：CA1184186A

公开(公告)日：1985-03-19

申请号：CA399115

申请日：1982-03-23

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETZSCHMAR ROLF ,  LEHMANN HANS D ,  FRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER ,  TREIBER HANS J ,  DENGEL FERDINAND ,  FRANK WOLFRAM ,  KURBJUWEIT HANS-GEORG ,  MUELLER CLAUS D

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18 ,  C07C121/78

Abstract: m-Cyano-1,m-dipheny-aza-alkane derivatives of the formula I I wherein Rl, R2, R3, R4, R5, R6, R7, R8, m and n have the meanings given in the description, and salts thereof with physiologically tolerated acids,are useful in treating cardiovascular disorders,

公开(公告)号：CA1180706A

公开(公告)日：1985-01-08

申请号：CA381703

申请日：1981-07-14

Applicant: BASF AG

Inventor： EILINGSFELD HEINZ ,  NEUMANN PETER ,  SEYBOLD GUENTHER ,  LENKE DIETER ,  FRIEDRICH LUDWIG

IPC: A61K31/425 ,  A61K31/428 ,  A61P37/08 ,  C07D277/60 ,  C07D277/82 ,  C07D417/00

Abstract: Cycloalkano-thiazolyl-oxamic acids and their esters, processes for their preparation, and therapeutic agents which contain these compounds and are useful in the treatment of allergic disorders.

公开(公告)号：NO840213A

公开(公告)日：1984-07-23

申请号：NO840213

申请日：1984-01-20

Applicant: BASF AG

Inventor： ROSSY PHILLIP A ,  THYES MARCO ,  FRANKE ALBRECHT ,  KOENIG HORST ,  LEHMANN HANS DIETER ,  GRIES JOSEF ,  FRIEDRICH LUDWIG ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00 ,  C07D

CPC classification number: C07D231/12 ,  C07D233/56 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D249/08 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12

公开(公告)号：DK24984A

公开(公告)日：1984-07-23

申请号：DK24984

申请日：1984-01-20

Applicant: BASF AG

Inventor： ROSSY PHILLIP A ,  THYES MARCO ,  FRANKE ALBRECHT ,  KOENIG HORST ,  LEHMANN HANS DIETER ,  GRIES JOSEF ,  FRIEDRICH LUDWIG ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00 ,  C07D

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

公开(公告)号：FI840224A0

公开(公告)日：1984-01-19

申请号：FI840224

申请日：1984-01-19

Applicant: BASF AG

Inventor： ROSSY PHILLIP A ,  THYES MARCO ,  FRANKE ALBRECHT ,  KOENIG HORST ,  LEHMANN HANS DIETER ,  GRIES JOSEF ,  FRIEDRICH LUDWIG ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00 ,  C07D

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.