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公开(公告)号：CA2101010A1
公开(公告)日：1994-01-23
申请号：CA2101010
申请日：1993-07-21
Applicant: HOECHST AG
Inventor： AHLERS MICHAEL , GLOMBIK HEINER , MUELLNER STEFAN , WALCH AXEL
IPC: A61K31/785 , A61P3/06 , C08F8/12 , C08F26/00 , C08F26/02 , C08F226/00 , A23L1/30 , A61K47/32
Abstract: Crosslinked, nitrogen-containing vinyl copolymers, processes for their preparation and the use of these compounds Crosslinked, nitrogen-containing vinyl copolymers having units of the formula I I and physiologically tolerated salts thereof, in which, in formula I, A1, A2, R, w, x, y and z have the meanings given, a process for their preparation and the use of the compounds as medicaments, active compound carriers and foodstuff auxiliaries are described.
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公开(公告)号：ES2123994T3
公开(公告)日：1999-01-16
申请号：ES95923321
申请日：1995-06-13
Applicant: HOECHST AG
Inventor： HORSCH BRIGITTE , AHLERS MICHAEL , KRETZSCHMAR GERHARD , BARTNIK ECKART , SEIFFGE DIRK
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公开(公告)号：ZA951910B
公开(公告)日：1995-11-13
申请号：ZA951910
申请日：1995-03-08
Applicant: HOECHST AG
Inventor： AHLERS MICHAEL , WALCH AXEL , SEIPKE GERHARD , RUSSEL-JONES GREGORY
Abstract: Nanoparticles contg. an active ingredient (A) and a poly (ketal tartaric acid amide) (B) with at least 95 mole% of repeating units of formula (I) are new: X = NH; R2 = alkyl or cycloalkyl, opt. with 1 or more inert substits.
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公开(公告)号：NZ270648A
公开(公告)日：1995-09-26
申请号：NZ27064895
申请日：1995-03-07
Applicant: HOECHST AG
Inventor： AHLERS MICHAEL , WALCH AXEL , SEIPKE GERHARD , RUSSELL-JONES GREGORY
Abstract: Nanoparticles contg. an active ingredient (A) and a poly (ketal tartaric acid amide) (B) with at least 95 mole% of repeating units of formula (I) are new: X = NH; R2 = alkyl or cycloalkyl, opt. with 1 or more inert substits.
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35.发明专利
公开(公告)号：NZ248192A
公开(公告)日：1995-05-26
申请号：NZ24819293
申请日：1993-07-20
Applicant: HOECHST AG
Inventor： AHLERS MICHAEL , GLOMBIK HEINER , GRABLEY SUSANNE , GRANZER ERNOLD , MULLNER STEFAN , WALCH AXEL , XU GUAN-YU
IPC: A23L33/00 , A61K31/785 , A61K47/30 , A61P3/06 , A61P3/12 , C08F8/12 , C08F26/00 , C08F226/02 , C08F8/44 , C08F8/32 , C08J3/24 , C08F26/02 , A23L1/29 , A23L1/307
Abstract: The invention relates to polyvinylamine derivatives containing hydrophilic centres, of the formula I in which R , R , R , X, w, x, y and z are as defined, and to a process for their preparation, and to the use of these compounds as medicaments (drugs, pharmaceuticals), active compound (active ingredient) carriers and as foodstuff auxiliaries. The preparation starts, in particular, from highly pure polyvinylamines containing the recurring unit of the formula Ia whose preparation is likewise described.a
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Patent Agency Ranking
公开(公告)号：HU9500698D0
公开(公告)日：1995-04-28
申请号：HU9500698
申请日：1995-03-08
Applicant: HOECHST AG
Inventor： SEIPKE GERHARD , WALCH AXEL , AHLERS MICHAEL , RUSSEL-JONES GREGORY
Abstract: Nanoparticles contg. an active ingredient (A) and a poly (ketal tartaric acid amide) (B) with at least 95 mole% of repeating units of formula (I) are new: X = NH; R2 = alkyl or cycloalkyl, opt. with 1 or more inert substits.
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公开(公告)号：NO950889D0
公开(公告)日：1995-03-08
申请号：NO950889
申请日：1995-03-08
Applicant: HOECHST AG
Inventor： AHLERS MICHAEL , WALCH AXEL , SEIPKE GERHARD , RUSSELL-JONES GREGORY JOHN
Abstract: Nanoparticles contg. an active ingredient (A) and a poly (ketal tartaric acid amide) (B) with at least 95 mole% of repeating units of formula (I) are new: X = NH; R2 = alkyl or cycloalkyl, opt. with 1 or more inert substits.
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公开(公告)号：ZA9309270B
公开(公告)日：1994-08-08
申请号：ZA9309270
申请日：1993-12-10
Applicant: HOECHST AG
Inventor： STAHL WILHELM , AHLERS MICHAEL , WALCH AXEL , BARTNIK ECKART , KRETZSCHMAR GERHARD , GRABLEY SUSANNE , SCHLEYERBACH RUDOLF
IPC: A61K20060101 , C07H20060101 , C07H , A61K
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公开(公告)号：HU9303538D0
公开(公告)日：1994-04-28
申请号：HU9303538
申请日：1993-12-10
Applicant: HOECHST AG
Inventor： STAHL WILHELM , AHLERS MICHAEL , WALCH AXEL , BARTNIK ECKHART , KRETZSCHMAR GERHARD , GRABLEY SUSANNE , SCHLEYERBACH RUDOLF
IPC: A61K31/715 , A61K31/765 , A61K31/785 , A61K31/80 , A61K47/48 , A61K49/00 , A61P29/00 , A61P31/04 , A61P31/12 , A61P35/00 , A61P43/00 , C07H15/04 , C07H15/203 , C08B37/00 , C08G63/00 , C08G63/06 , C08G64/00 , C08G64/42 , C08G65/16 , C08G67/04 , C08G69/00 , C08G69/10 , C08G73/16
Abstract: The invention relates to physiologically compatible and physiologically degradable polymer-based carbohydrate receptor blocker with an HLB of 10 to 20, containing: carbohydrate portion - bifunctional spacer - hydrophilic biodegradable polymer - potentiator, where the carbohydrate portion consists of 1 to 20 naturally occurring, identical or different, monosaccharide units and is coupled via one or more bifunctional spacers, which is a natural or synthetic molecule, to a hydrophilic biodegradable polymer, and the polymer in turn is the carrier of one or more spacers and the hydrophilic biodegradable polymer is additionally linked to the potentiator which is a crosslinker, one or more groups with hydrophobic, hydrophilic or ionic properties or a solubility improver, to a method for the preparation and to its use in vivo for blocking carbohydrate-recognising receptors. The carbohydrate receptor blocker induces no incompatibility reaction in vivo either in its totality or in the form of breakdown products.
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公开(公告)号：ZA935267B
公开(公告)日：1994-04-18
申请号：ZA935267
申请日：1993-07-21
Applicant: HOECHST AG
Inventor： AHLERS MICHAEL , MUELLNER STEFAN , WALCH AXEL , GLOMBIK HEINER
Abstract: The invention relates to crosslinked, nitrogen-containing vinyl copolymers containing units of the formula I and the physiologically acceptable salts thereof, where, in formula I, A1, A2, R, w, x, y and z are as defined, to a process for their preparation, and to the use of the compounds as medicaments (drugs, pharmaceuticals), active compound (active ingredient) carriers and as foodstuff auxiliaries.
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