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    적외선 비선형 분자진동 분광 이미징 장치
    33.
    发明授权
    적외선 비선형 분자진동 분광 이미징 장치 失效
    用于红外线非线性分子显微镜的成像装置

    公开(公告)号：KR100860947B1

    公开(公告)日：2008-09-30

    申请号：KR1020070055952

    申请日：2007-06-08

    Applicant: 한국표준과학연구원

    Inventor： 이재용 ,  이은성

    IPC: G01N21/35 ,  G01N21/00 ,  G01B9/02 ,  G01N33/483

    CPC classification number: G01N21/35 ,  G01N21/1717 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/636 ,  G01N2021/1772 ,  G01N2021/451 ,  G01N2201/0492

    Abstract: An imaging apparatus for infrared ray nonlinear molecular vibration spectrum is provided to improve detection sensitivity by using molecular vibration and infrared pump beam. An imaging apparatus for infrared rays nonlinear molecular vibration spectrum comprises a pump beam source(10) generating an infrared pump beam, a probe beam source(20) generating a probe beam, a beam combiner(30) combining the pump beam and the probe beam, a scanner(40) scanning the combined pump and probe beam to a plane, a first optical collector(50) collecting the scanned pump and probe beam at a local point, a first collimator(60), a first dichroic beam splitter(70), a reference interferometer(80), an optical interferometer beam combiner(90), a photodetector(100), and a data analyzer(110). The infrared pump beam excites molecules of medium forming a sample. The probe beam detects a coherence state of the excited molecules. The beams collected by the first optical collector are subject to an interaction with the sample, and aligned in parallel through first collimator. The first dichroic beam splitter separates a phase-shift probe beam from the collimated beam by removing an infrared pump beam. The reference interferometer generates a reference probe beam by separating a probe beam from the scanned beam. The optical interferometer beam combiner combines the phase-shift probe beam to the reference probe beam. The photodetector detects intensity of a molecular oscillation interference optical signal through the combined phase-shift and reference probe beam. The data analyzer generates a spectrum signal according to a coherence intensity of the molecule oscillation of the sample by collecting the optical signal.

    Abstract translation: 提供了一种用于红外线非线性分子振动谱的成像装置，通过使用分子振动和红外泵浦光束来提高检测灵敏度。 一种用于红外线非线性分子振动光谱的成像设备包括产生红外泵浦光束的泵浦光束源（10），产生探测光束的探测光束源（20），组合泵浦光束和探测光束的光束组合器（30） 扫描器（40）将组合的泵和探针光束扫描到平面;第一光学收集器（50），其在局部点处收集扫描的泵和探测光束;第一准直器（60）;第一分色分束器（70） ），参考干涉仪（80），光干涉仪光束组合器（90），光电检测器（100）和数据分析器（110）。 红外泵浦束激发形成样品的介质分子。 探测光束检测激发的分子的相干状态。 由第一光学收集器收集的光束经受与样品的相互作用，并且通过第一准直仪平行对准。 第一分色光束分离器通过去除红外泵浦光束将相移探测光束与准直光束分离。 参考干涉仪通过将探测光束与扫描光束分离而产生参考探测光束。 光干涉仪光束组合器将相移探测光束组合到参考探测光束。 光电检测器通过组合的相移和参考探测光束来检测分子振荡干涉光信号的强度。 数据分析器通过收集光信号，根据样品的分子振荡的相干强度产生频谱信号。

    전자현미경 복수 시료 연속관찰 시스템
    34.
    发明公开
    전자현미경 복수 시료 연속관찰 시스템 有权
    电子显微镜多重样品连续观察系统

    公开(公告)号：KR1020170121888A

    公开(公告)日：2017-11-03

    申请号：KR1020160050729

    申请日：2016-04-26

    Applicant: 한국기초과학지원연구원

    Inventor： 정종만 ,  권희석 ,  이상철 ,  김진규 ,  한철수 ,  허양훈

    IPC: G01N21/13 ,  G01N3/04 ,  G01N1/06

    CPC classification number: G01N21/13 ,  G01N1/06 ,  G01N3/04 ,  G01N2001/065 ,  G01N2021/135 ,  G01N2201/0492

    Abstract: 본발명은경통외부에층상으로장착되어있는복수시료가순차적으로전자현미경경통으로삽입되어관찰할수 있도록함으로써시료관찰소요시간을대폭절약하고, 복수의시료를연속관찰할수 있도록하는전자현미경복수시료연속관찰시스템에관한것으로, 보다상세하게는 (A) 시료가장착되는판형의시료장착판; (B) 내부에상기복수개의시료장착판이층상으로적층되는결합부, 관찰이완료된시료장착판을보관하는보관부, 및상기시료장착판이하나씩전자현미경의경통부내부로왕복이동되어시료스테이지에장착-탈착될수 있도록경통부와연통된개방구가형성되어있는밀폐형시료챔버; (C) 시료챔버의결합부에적층된것 중하나의시료장착판과임시결합하고밀어서상기시료장착판을경통부내의시료스테이지에장착하고, 관찰이종료되면당겨서상기보관부로이송한후 임시결합을해제하여관찰이종료된시료장착판을보관부로이송하는이송수단;을포함하는전자현미경용복수시료연속관찰시스템에관한것이다.

    Abstract translation: 观察本发明的多个样品连续电子显微镜是显著节省样品观察时间，并且通过使可观察到被插入到多个标本外筒被安装在一个顺序层电子显微镜镜筒中连续地观察所述多个采样的 （A）样品安装在其上的板状样品安装板; （B）的耦合部的内部到所述多个样品安装堆叠成层的板，用于观察样品安装板的保持的存储部已经完成，和试样安装板往复移动到一个电子显微镜的安装在样品台上的桶 - 密封的试样室，其具有与透镜镜筒连通以便可拆卸的开口; （C）层叠时至样品室将重耦合我的样品安装板和暂时推动安装在试样上在一个筒中的样品台安装板的卡合部，和观察通过拉动完成，然后转移到所述存储禁用临时接合 以及用于将观察到的样品安装板转移到存储部分的转移装置。

    INTEGRATED CALIBRATION SAMPLE BAY FOR FLUORESCENCE READERS
    36.
    发明公开
    INTEGRATED CALIBRATION SAMPLE BAY FOR FLUORESCENCE READERS 审中-公开
    荧光读码器的集成校准样品室

    公开(公告)号：EP2470937A1

    公开(公告)日：2012-07-04

    申请号：EP10732563.1

    申请日：2010-06-28

    Applicant: Cellomics, Inc.

    Inventor： SALISBURY, Richard, C. ,  VANDENBERG, Dirk, John ,  IPPOLITO, Kim, Anthony

    IPC: G02B21/26 ,  G01N21/27

    CPC classification number: G01N21/276 ,  G01N21/278 ,  G01N21/6452 ,  G01N21/6458 ,  G01N2201/0492 ,  G02B21/32

    Abstract: A stage assembly, an imaging system that uses the stage assembly, and methods for using the stage assembly in a high content screening system. The stage assembly includes a stage having a top surface and an opposing bottom surface and an opening extending between the top and bottom surfaces to receive a specimen plate. The stage assembly also includes a calibration sample bay formed in the stage. A calibration sample can also be secured within the calibration sample bay.

    Abstract translation: 舞台组装，使用舞台组装的成像系统，以及在高内容筛选系统中使用舞台组装的方法。 台架组件包括具有顶部表面和相对的底部表面的台架以及在顶部表面和底部表面之间延伸以接收标本板的开口。 台架组件还包括在台架中形成的校准样品台。 校准样品也可以固定在校准样品台内。

    Automatic cell sample classifying apparatus
    40.
    发明公开
    Automatic cell sample classifying apparatus 失效
    自动Vorrichtung zur Klassifizierung einer Zellprobe。

    公开(公告)号：EP0251281A2

    公开(公告)日：1988-01-07

    申请号：EP87109342.3

    申请日：1987-06-29

    Applicant: HITACHI, LTD.

    Inventor： Sakuraba, Shinichi ,  Matsushita, Hajime ,  Kurimura, Masaaki

    IPC: G01N15/14 ,  G01N21/25 ,  G01N35/00

    CPC classification number: G06K9/00127 ,  G01N1/30 ,  G01N15/1468 ,  G01N21/25 ,  G01N2201/0492

    Abstract: A stain discriminating apparatus in which light rays having at least one light component having a wave­length in a predetermined range is projected to a cell sample (2) to discriminate the staining method by which the cell sample has been stained on the basis of the light intensity of the light component transmitted through the sample and having the wavelength (530 nm) in the predeter­mined range. An automatic cell sample classifying apparatus in which a plurality of cell sample slides (2) are sequentially fed to the stain discriminating apparatus (6) to determine the staining method by which the cell samples have been stained, respectively. One of the examination/classification programs previously stored in a memory (82) is read out according to the staining method as discriminated and the cell samples are processed in accordance with the program as read out.

    Abstract translation: 一种污染鉴定装置，其中具有至少一种具有预定范围波长的光分量的光线投射到细胞样品（2），以鉴别细胞样品已经被染色的染色方法，基于光强度 的透射通过样品并且具有预定范围的波长（530nm）的光分量。 一种自动细胞样品分选装置，其中多个细胞样品载玻片（2）被顺序地送入染色鉴定装置（6），以确定细胞样品染色的染色方法。 先前存储在存储器（82）中的检查/分类程序之一根据所识别的染色方法读出，并且根据读出的程序按照程序处理单元样本。

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