Abstract:
PURPOSE: A sweetness enrichment composition is provided to have excellent sweetness enrichment, especially, the almost the same or superior sweetness effect than the conventional sweetener, and decreased calories in terms of nutrition by including glycan separated from soy sauce. CONSTITUTION: A sweetness enrichment composition includes glycan represented by general formula 1. (Hex)_5-(HexNac)_1 In the general formula, Hex is hexose, and HexNac is N-acetylhexosamine. The glycan is included in soy sauce or a soy sauce fraction. The sweetness enrichment composition includes the glycopeptide fraction of soy sauce. A glycopeptide fraction yielding step comprises: a step of removing precipitate by centrifuging soy sauce; and a step of separating the glycopeptite fraction with 500-10,000 Da of a molecular weight by ultrafiltrating the product.
Abstract:
본 발명은 장기 숙성 재래 간장에서 분리한 메일라드 펩타이드를 유효성분으로 함유하는 TRPV1 활성 관련 질환 또는 염증 관련 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 메일라드 펩타이드는 TRPV1에 대해서 작용제 및 길항제로 모두 작용함으로써 TRPV1 활성을 조절하는 조절제로 작용하여 통증, 신경 관련 질환, 긴급 배변, 염증성 장 질환, 호흡기 질환, 요실금, 방광 과민증, 신경성증/알레르기성/염증성 피부질환, 피부, 눈 또는 점막의 자극, 청각 과민증, 이명, 전정 과민증, 심장 질환 등과 같은 TRPV1 활성 관련 질환의 예방 또는 치료용 약학적 조성물로 사용되거나, COX-2 활성을 저해할 수 있어 류마티스성 열, 인플루엔자, 감기, 목 통증, 두통, 치통, 염좌, 신경통, 활막염, 류마티스성 관절염, 퇴행성 관절 질환, 통풍, 강직 척추염, 건선, 피부염 등과 같은 염증 관련 질환의 예방 또는 치료용 약학적 조성물로 유용하게 사용될 수 있다. 간장, 메일라드 펩타이드, 바닐로이드 수용체, COX-2, 조절자
Abstract:
PURPOSE: Provided is a composition for prevention and treatment of cardiovascular diseases using Schizandra chinensis Baillon extract which has estrogen-like activity. CONSTITUTION: A composition for prevention and treatment of cardiovascular diseases is characterized by containing Schizandra chinensis Baillon extract concentrated to 0.1-0.3mg/ml and pharmaceutically acceptable carrier. The extract of Schizandra chinensis Baillon is obtained by using the extraction solvent selected from the group consisting of water, lower alcohol and organic solvents.
Abstract:
PURPOSE: Provided are a composition for nitric oxide-mediated vasorelaxation using Rhizoma ligusticum wallichii and a pharmaceutical composition using the same. The composition is useful for prevention and treatment of cardiopulmonary disorders. CONSTITUTION: A composition for nitric oxide-mediated vasorelaxation using Rhizoma ligusticum wallichii is characterized by at least one of Cnidium officinale, Cnidium officinale powder and Cnidium officinale extract as an active ingredient. The Cnidium officinale extract is obtained by using water, lower alcohol or organic solvent as an extraction solvent, wherein the organic solvent includes acetone, chloroform, methylene chloride, ether, ethylacetate or hexane.
Abstract:
PURPOSE: A nitrogen monoxide forming composition prepared by using rice and Monascus ruber IFO32318 as a main component and a pharmaceutical composition are provided, which can be produced in a simple manner, are suitable for mass-production and have stability and safety on physiological activity. CONSTITUTION: The nitrogen monoxide forming composition is characterized in that it contains Monascus and/or powder thereof and/or abstracts thereof. For an example, Monascus extracts are dipped in rice water at 50deg.C for 3hr and innoculated in Monascus ruber IFO32318, fermented at 30deg.C for 2days, fermented aerobically and treated to produce the titled nitrogen monoxide forming composition.