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    46.
    发明专利
    未知

    公开(公告)号：AT269696T

    公开(公告)日：2004-07-15

    申请号：AT01105544

    申请日：2001-03-06

    Applicant: BASF AG

    Inventor： ANGEL MAXIMILIAN DR ,  KOLTER KARL DR ,  SANNER AXEL DR ,  GOTSCHE MICHAEL DR

    IPC: A61K8/02 ,  A61K8/11 ,  A61K8/64 ,  A61K8/73 ,  A61K8/86 ,  A61K9/48 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/42 ,  B01J13/14 ,  C08F8/12 ,  C08F283/06

    Abstract: Hard capsules contain: (A) polymer obtained by radical polymerization of at least one 1-24C carboxylic acid vinyl ester (a) in presence of a polyether compound (b) and optionally comonomer(s) (c), followed by at least partial saponification of the ester residues in the obtained copolymer; (B) optional structure-improving auxiliaries; and (C) further conventional components. Hard capsules contain: (A) polymer obtained by radical polymerization of at least one 1-24C carboxylic acid vinyl ester (a) in presence of a polyether compound (b) and optionally comonomer(s) (c) (provided that if comonomers (c) are absent then polyether (b) has number average molecular weight of 10000 or less), followed by at least partial saponification of the ester residues in the obtained copolymer; (B) optional structure-improving auxiliaries; and (C) further conventional components. An Independent claim is included for the use of the polymers (A) for the preparation of hard capsules as above, provided that if (c) are absent, then (b) has number average molecular weight 300-10000.

    47.
    发明专利
    未知

    公开(公告)号：DK0868910T3

    公开(公告)日：2003-02-24

    申请号：DK98103626

    申请日：1998-03-02

    Applicant: BASF AG

    Inventor： KOLTER KARL DR ,  TIEFENSEE KRISTIN DR ,  ZEITZ KATRIN DR

    IPC: A61K47/04 ,  A61K9/20 ,  A61K9/32 ,  A61K47/12 ,  A61K47/32 ,  A61K47/38

    Abstract: Use of redispersible polymer powders or granules as binders for preparing solid compositions, where the powders or granules comprise: (a) 10-95 wt.% polyvinyl acetate; (b) 5-90 wt.% of a N-vinylpyrrolidone polymer; (c) 0-20 wt.% of another water-soluble or water-swellable material; (d) 0-20 wt.% of a water-insoluble dusting agent; and optionally (e) further additives, and where the proportion of the binder in the dosage form is 0.5-20 wt.%. Also claimed are solid compositions with a binder comprising components (a)-(e) in the amounts specified above, where the binder makes up 0.5-20% of the total.

    48.
    发明专利
    未知

    公开(公告)号：AT230259T

    公开(公告)日：2003-01-15

    申请号：AT98103626

    申请日：1998-03-02

    Applicant: BASF AG

    Inventor： KOLTER KARL DR ,  TIEFENSEE KRISTIN DR ,  ZEITZ KATRIN DR

    IPC: A61K47/04 ,  A61K9/20 ,  A61K9/32 ,  A61K47/12 ,  A61K47/32 ,  A61K47/38

    Abstract: Use of redispersible polymer powders or granules as binders for preparing solid compositions, where the powders or granules comprise: (a) 10-95 wt.% polyvinyl acetate; (b) 5-90 wt.% of a N-vinylpyrrolidone polymer; (c) 0-20 wt.% of another water-soluble or water-swellable material; (d) 0-20 wt.% of a water-insoluble dusting agent; and optionally (e) further additives, and where the proportion of the binder in the dosage form is 0.5-20 wt.%. Also claimed are solid compositions with a binder comprising components (a)-(e) in the amounts specified above, where the binder makes up 0.5-20% of the total.

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