公开(公告)号：BR9507328A

公开(公告)日：1997-09-30

申请号：BR9507328

申请日：1995-04-05

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/16 ,  A61K9/22

Abstract: Slow-release matrix pellets with a spherical or lenticular shape and uniform maximum diameters in the range from 0.5 to 4 mm, composed ofa) 0.1-87% by weight of at least one biologically active compound,b) 5-50% by weight of at least one water-insoluble polymer,c) 5-45% by weight of at least one lipophilic component as plasticizer for polymer b),d) 3-40% by weight of a natural or semisynthetic gel former,e) 0-50% by weight of one or more conventional formulation aids.

公开(公告)号：ZA962242B

公开(公告)日：1997-09-22

申请号：ZA962242

申请日：1996-03-20

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  RIEGER JENS ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/20 ,  A61K9/16 ,  A61K47/30 ,  A61K

公开(公告)号：ZA9602243B

公开(公告)日：1997-09-22

申请号：ZA9602243

申请日：1996-03-20

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG

IPC: A61K9/14 ,  A61K9/20 ,  B01J2/20 ,  B01J ,  A61K

CPC classification number: A61K9/2013 ,  A61K9/146 ,  A61K9/2027 ,  A61K9/2095 ,  B01J2/20

公开(公告)号：AU1541697A

公开(公告)日：1997-08-20

申请号：AU1541697

申请日：1997-01-17

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  ROSENBERG JOERG

IPC: A61K47/04 ,  A61K9/20 ,  A61K31/00 ,  A61K31/19 ,  A61K31/192 ,  A61K45/00 ,  A61K47/32 ,  A61P25/00 ,  A61P29/00

Abstract: Preparations of non-steroidal analgesics with antipyretic and antiinflammatory effect are obtainable by extrusion and shaping of a melt, comprising, besides one or more active ingredients, a mixture ofa) 40-99.5% by weight of a homopolymer of N-vinylpyrrolidone with a Fikentscher K value of 30,b) 0.25-59.75% by weight of a water-soluble copolymer of N-vinylpyrrolidone, andc) 0.25-10% by weight of one or more physiologically acceptable salts of sodium or potassium,where the stated amounts are based on the total of components a), b) and c).

公开(公告)号：NO972912A

公开(公告)日：1997-08-19

申请号：NO972912

申请日：1997-06-20

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16 ,  A61J3/06

CPC classification number: B30B11/165 ,  A61J3/10 ,  A61K9/2072 ,  Y10S53/90

公开(公告)号：CA2243522A1

公开(公告)日：1997-07-31

申请号：CA2243522

申请日：1997-01-17

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG

IPC: A61K9/20 ,  A61K31/19

Abstract: The invention concerns preparation of non-steroidal analgesics with antipyretic and antiphlogistic effect, obtained through extrusion and moulding of a melt containing in addition one or more substances in a mixture of: a) 40 to 99.5 wt% of a homopolymer of N -vinylpyrrolidone with a K value according to Fikentscher of 30; b) 0.25 to 59.75 wt% of a water-soluble copolymer of Nvinylpyrr olidone; and c) 0.25 to 10 wt% of one or more physiologically ac ceptable sodium or potassium salts, where the quantities refer to the total of the components a), b) and c).

公开(公告)号：FI972631A0

公开(公告)日：1997-06-18

申请号：FI972631

申请日：1997-06-18

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16 ,  A61J

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：FI972555A

公开(公告)日：1997-06-16

申请号：FI972555

申请日：1997-06-16

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  GRABOWSKI SVEN ,  BREITENBACH JOERG

IPC: A61J1/03 ,  A61J3/00 ,  A61J3/10 ,  A61K9/20 ,  A61K9/28 ,  B30B11/16 ,  B65B9/04 ,  A61J

公开(公告)号：AU7491296A

公开(公告)日：1997-05-15

申请号：AU7491296

申请日：1996-10-23

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  HARTL AXEL PAUL ,  HOFMANN JURGEN ,  ROSENBERG JOERG ,  SCHIESSL MICHAEL ,  ZETTLER HANS DIETER

IPC: A61J3/10 ,  A61K9/20 ,  A61K9/24 ,  A61K9/28 ,  A61K31/07 ,  A61K31/167 ,  A61K31/192 ,  A61K31/277 ,  A61K31/355 ,  A61K31/375 ,  A61K31/401 ,  A61K31/4422 ,  A61K31/52 ,  A61K31/522 ,  A61K31/60

Abstract: PCT No. PCT/EP96/04601 Sec. 371 Date Apr. 15, 1998 Sec. 102(e) Date Apr. 15, 1998 PCT Filed Oct. 23, 1996 PCT Pub. No. WO97/15293 PCT Pub. Date May 1, 1997The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.

公开(公告)号：NO964939L

公开(公告)日：1997-01-17

申请号：NO964939

申请日：1996-11-20

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG

IPC: A61K9/14 ,  A61K9/20 ,  B01J2/20

Abstract: PCT No. PCT/EP96/01047 Sec. 371 Date Nov. 21, 1996 Sec. 102(e) Date Nov. 21, 1996 PCT Filed Mar. 12, 1996 PCT Pub. No. WO96/29061 PCT Pub. Date Sep. 26, 1996A process for producing active substance compositions in the form of a solid solution of the active substance in a polymer matrix, which comprises melt extrusion of the active substance in nonionic form together with a polymer and a salt.