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51.发明授权황매목 추출물을 유효성분으로 포함하는 스트레스성 질환의 예방 또는 치료용 조성물 有权用于预防或治疗包含LINDERA OBTUSILOBA BL的应力相关疾病的组合物。 提取物作为活性成分
公开(公告)号：KR101232853B1
公开(公告)日：2013-02-13
申请号：KR1020120033875
申请日：2012-04-02
Applicant: 한국식품연구원
CPC classification number: A61K36/54 , A23V2200/322 , A61K2236/331 , A61K2236/333
Abstract: PURPOSE: A composition containing a Lindera obtusiloba BL. extract for preventing or treating stress diseases is provided to suppress glucocorticoid receptor activity and to suppress signal transduction induced by stress. CONSTITUTION: A composition for preventing or treating depression contains a Lindera obtusiloba BL. extract as an active ingredient. The extract is prepared by extracting with an organic solvent, water, or a mixture thereof. The organic solvent is ethanol, methanol, acetone, hexane, ethyl acetate, or methylene chloride. The extract is prepared using an ultrasonicator. The composition suppresses glucocorticoid receptor activation and reduces c-fos expression. A food composition for treating or relieving depression contains the extract as an active ingredient.
Abstract translation: 目的：含有Lindera obtusiloba BL的组合物。 提供用于预防或治疗应激疾病的提取物以抑制糖皮质激素受体活性并抑制由应激引起的信号转导。 构成：用于预防或治疗抑郁症的组合物含有林德氏黑莓（Lindera obtusiloba BL）。 提取物作为活性成分。 提取物通过用有机溶剂，水或其混合物萃取来制备。 有机溶剂为乙醇，甲醇，丙酮，己烷，乙酸乙酯或二氯甲烷。 使用超声波器制备提取物。 该组合物抑制糖皮质激素受体激活并降低c-fos表达。 用于治疗或缓解抑郁症的食物组合物含有作为活性成分的提取物。
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52.发明公开
公开(公告)号：KR1020120132653A
公开(公告)日：2012-12-07
申请号：KR1020110050474
申请日：2011-05-27
Applicant: 한국식품연구원
IPC: A61K36/899 , A61P25/24 , A61P25/22 , A61P25/20
Abstract: PURPOSE: A composition containing rice bran extract for preventing or treating sleep disorder, anxiety, or depression is provided to reduce sleep latency and to enable long-term use without side effects such as cognitive impairment. CONSTITUTION: A pharmaceutical composition for preventing or treating deep sleep, anxiety, or depression contains rice bran extract or powder as an active ingredient. The rice extract is prepared using water, an organic solvent, or a mixture thereof. The organic solvent is low carbon number alcohol, hexane, acetone, ethyl acetate, chloroform, or diethyl ether. The rice bran extract includes an oil fraction, a liquid phase fraction, or a wax fraction of the rice bran extract. The rice extract also includes a fraction. A food composition for preventing or treating sleep disorder, anxiety, or depression contains the rice bran extract as an active ingredient. [Reference numerals] (AA) Time for sleep onset(minutes); (BB) BEE-H subfraction(250 mg/kg)
Abstract translation: 目的：提供含有米糠提取物用于预防或治疗睡眠障碍，焦虑或抑郁症的组合物，以减少睡眠潜伏期并使其能够长期使用而无副作用，如认知障碍。 构成：用于预防或治疗深度睡眠，焦虑或抑郁的药物组合物含有米糠提取物或粉末作为活性成分。 水提取物是使用水，有机溶剂或其混合物制备的。 有机溶剂为低碳值醇，己烷，丙酮，乙酸乙酯，氯仿或二乙醚。 米糠提取物包括油级分，液相级分或米糠提取物的蜡级分。 水稻提取物还包括一部分。 用于预防或治疗睡眠障碍，焦虑或抑郁的食物组合物含有米糠提取物作为活性成分。 （参考号）（AA）睡眠开始时间（分钟）; （BB）BEE-H次级分（250mg / kg）
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公开(公告)号：KR101169217B1
公开(公告)日：2012-07-27
申请号：KR1020100057339
申请日：2010-06-17
Applicant: 한국식품연구원
Abstract: 본 발명은 스코파론(scoparone)을 고농도로 함유하는 인진쑥 에탄올 추출물을 인진쑥 열수 추출물에 첨가하여 인진쑥 열수 추출물 내의 스코파론의 농도를 일정하게 유지하는 단계를 포함하는 스코파론의 농도가 일정하게 유지되는 인진쑥 음료 조성물의 제조 방법 및 상기 방법에 의해 제조된 스코파론(scoparone)의 농도가 일정하게 유지되는 인진쑥 음료 조성물에 관한 것으로, 본 발명의 스코파론(scoparone)의 농도가 일정하게 유지되는 인진쑥 음료 조성물은 지방간에 효율적으로 이용할 수 있다.
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54.发明公开
公开(公告)号：KR1020120078898A
公开(公告)日：2012-07-11
申请号：KR1020110000197
申请日：2011-01-03
Applicant: 한국식품연구원
IPC: A61K31/12 , A61K36/484 , A23L33/00 , A61P25/20
CPC classification number: Y02A50/415
Abstract: PURPOSE: A composition containing isoliquiritigenin for activating GABAA-benzodiazepine receptors is provided to enhance deep sleep, sedation, and anti-anxiety. CONSTITUTION: A composition for activating GABAA-benzodiazepine receptors contains a compound of chemical formula 1. A composition for deep sleep, sedation, anti-anxiety, or anti-convulsion contains the compound of chemical formula 1. A functional food for deep sleep, sedation, anti-anxiety, or anti-convulsion contains the compound of chemical formula 1. The functional food contains Glycyrrhiza uralensis Fischer extract. The extract is prepared by extracting Glycyrrhiza uralensis Fischer with 28-32% ethanol at 38-42 Deg.C for 10-14 hours.
Abstract translation: 目的：提供含有用于激活GABA A - 苯并二氮杂受体的异iqu igen素的组合物，以增强深度睡眠，镇静和抗焦虑。 组成：用于激活GABAA-苯并二氮杂受体的组合物含有化学式1的化合物。用于深度睡眠，镇静，抗焦虑或抗惊厥的组合物含有化学式1的化合物。用于深度睡眠，镇静的功能性食物 ，抗焦虑或抗惊厥含有化学式1的化合物。功能性食品含有甘草黄芪提取物。 提取物采用28-32％乙醇在38-42℃下提取甘草10-7小时。
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公开(公告)号：KR101155426B1
公开(公告)日：2012-06-15
申请号：KR1020100091517
申请日：2010-09-17
Applicant: 한국식품연구원
IPC: A23L33/00 , A61K31/7048 , A61K31/35 , A61P3/04
Abstract: PURPOSE: A food ingredient composition for suppressing the appetite of a user is provided to prevent the generation of side effect when using the composition for a long time. CONSTITUTION: A food ingredient composition for suppressing the appetite of a user contains more than one component selected from the group consisting of 3-hydroxy flavone, rutin, quercetin, flavonone, naringin, and hesperidin. The suppressing effect of the appetite is obtained by controlling the activity of ghrelin promoting the appetite of the user. The composition suppresses the activity of the ghrelin at 60-100deg C.
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Patent Agency Ranking
公开(公告)号：KR1020120029992A
公开(公告)日：2012-03-27
申请号：KR1020110078568
申请日：2011-08-08
Applicant: 한국식품연구원
IPC: A61K36/282 , A61P25/28 , A61P25/00
Abstract: PURPOSE: A composition for improving memory power and learning ability comprising extract from artemisia apiaceae as active ingredient is provided to control antioxidant activity and activity of acetylcholinesterase. CONSTITUTION: A composition for improving memory power and learning ability including Artemisia apiaceae extract as an active ingredient. A composition for preventing or treating cognitive disorder includes the Artemisia apiaceae extract as the active ingredient. The compositions for improving memory power, learning ability, and preventing or treating cognitive disorder have several functions as follow: suppressing activity of Acetylcholinesterase, antioxidant activity, controlling or eliminating generation of reactive oxygen species, acting as antagonist [antagonist of NMDA[N-methyl-D-aspartate] receptor. The cognitive disorder stands for dementia, formerly LDH, agnosia, amnesia, aphasia, parectropia, or delirium. A pharmaceutical composition for preventing or treating cognitive disorder includes therapeutic effective amount of composition including Artemisia apiaceae extracts and pharmaceutically allowed carrier.
Abstract translation: 目的：提供一种用于提高记忆力和学习能力的组合物，其包括作为活性成分的姬松蒿提取物，以控制乙酰胆碱酯酶的抗氧化活性和活性。 构成：用于提高记忆力和学习能力的组合物，包括蒿科植物提取物作为活性成分。 用于预防或治疗认知障碍的组合物包括蒿科艾蒿提取物作为活性成分。 用于提高记忆力，学习能力和预防或治疗认知障碍的组合物具有以下功能：抑制乙酰胆碱酯酶的活性，抗氧化活性，控制或消除作为拮抗剂的活性氧的产生[NMDA [N-甲基 -D-天冬氨酸]受体。 认知障碍代表痴呆，以前称为LDH，恶性呕吐症，遗忘症，失语症，副作用或del妄。 用于预防或治疗认知障碍的药物组合物包括治疗有效量的组合物，包括蒿科植物提取物和药学上允许的载体。
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公开(公告)号：KR1020110127998A
公开(公告)日：2011-11-28
申请号：KR1020100047576
申请日：2010-05-20
Applicant: 한국식품연구원
CPC classification number: A23L2/04 , A23L2/60 , A23L21/25 , A23V2250/208 , A23V2250/28 , A23V2250/6422 , A23V2300/24
Abstract: PURPOSE: Pine mushroom tea having improved storing property, and a producing method thereof are provided to use pine mushroom having low merchantable quality instead of wasting. CONSTITUTION: A producing method of pine mushroom tea comprises the following steps: heating a pine mushroom material containing slices pine mushrooms, and a pine mushroom extract in a weight ratio of 3:1 for 2 minutes at 100 deg C: heating a sugar material containing sugar, honey, oligosaccharide, and xylitol in a ratio of 4:4:4:1 for 2 minutes at 100 deg C; mixing the heated pine mushroom material and the sugar material in a weight ratio of 2:3; and adding a food additive selected from the group consisting of carrageenan, citric acid, vitamin C, or their compound.
Abstract translation: 目的：具有改善储藏性能的松蘑茶及其制造方法，使用具有低商品质量而不是浪费的松蘑。 构成：松蘑茶的制造方法，包括如下步骤：在100℃下加热含有松果蘑菇的松蘑菇材料，重量比为3:1的松木提取物2分钟：加热含有 糖，蜂蜜，寡糖和木糖醇，比例为4:4:4:1，在100℃下2分钟; 将加热的松木材料和糖料以2：3的重量比混合; 并加入选自角叉菜胶，柠檬酸，维生素C或其化合物的食品添加剂。
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公开(公告)号：KR1020110125959A
公开(公告)日：2011-11-22
申请号：KR1020100045617
申请日：2010-05-14
Applicant: 한국식품연구원
IPC: A61K36/704 , A61P7/02
CPC classification number: A61K36/704 , A23V2200/326 , A61K2236/333 , Y10S514/822
Abstract: PURPOSE: A pharmaceutical composition containing Polygonum multiflorum extract for reducing blood clot is provided to prevent and relieve adult diseases such as heart disease and stroke. CONSTITUTION: A pharmaceutical composition for reducing blood clot contains Polygonum multiflorum ethanol extract as an active ingredient. The ethanol is 70-90% ethanol. A functional food with an activity of reducing blood clot contains the Polygonum multiflorum ethanol extract as an active ingredient. The Polygonum multiflorum extract is contained in 0.02-50 wt% based on total pharmaceutical composition. The pharmaceutical composition is manufactured in the form of powder, granules, tablets, capsules, suspensions, syrup, external use formulation, and suppository.
Abstract translation: 目的：提供一种含有减少血块的茯苓提取物的药物组合物，用于预防和缓解成人疾病如心脏病和中风。 构成：用于减少血块的药物组合物含有枸杞多酚乙醇提取物作为活性成分。 乙醇为70-90％乙醇。 具有减少血块活性的功能性食品含有枸杞多酚乙醇提取物作为活性成分。 茯苓提取物含量为基于总药物组合物的0.02-50重量％。 药物组合物以粉末，颗粒，片剂，胶囊，悬浮液，糖浆，外用制剂和栓剂的形式制备。
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公开(公告)号：KR101049493B1
公开(公告)日：2011-07-15
申请号：KR1020100092045
申请日：2010-09-17
Applicant: 한국식품연구원
Abstract: PURPOSE: A composition containing Lepidium apefalum extract for enhancing memory and learning ability is provided to prevent or treat cognitive disorder. CONSTITUTION: A composition for enhancing memory and learning ability contains Lepidium apefalum extract as an active ingredient. A pharmaceutical composition for preventing and treating cognitive disorder contains Lepidium apefalum extract as an active ingredient. The Lepidium apefalum extract is prepared using a polar solvent or non-polar solvent. The polar solvent is water, alcohol, acetic acid, DMFO(dimethyl-formamide), and DMSO(dimethyl sulfoxide). The non-polar solvent is acetone, acetonitrile, ethyl acetate, methyl acetate, fluoroalkane, pentane, and hexane.
Abstract translation: 目的：提供含有提取记忆和学习能力的百日咳提取物的组合物，用于预防或治疗认知障碍。 构成：用于提高记忆力和学习能力的组合物，含有韭菜提取物作为活性成分。 一种用于预防和治疗认知障碍的药物组合物，含有虱属的提取物作为活性成分。 使用极性溶剂或非极性溶剂制备韭菜提取物。 极性溶剂是水，乙醇，乙酸，DMFO（二甲基甲酰胺）和DMSO（二甲基亚砜）。 非极性溶剂是丙酮，乙腈，乙酸乙酯，乙酸甲酯，氟烷烃，戊烷和己烷。
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公开(公告)号：KR1020100127599A
公开(公告)日：2010-12-06
申请号：KR1020090046109
申请日：2009-05-26
Applicant: 한국식품연구원
Abstract: PURPOSE: A liquid seasoning with antihypertensive action containing pine mushroom juice is provided to maintain blood pressure reduction effect and to ensure excellent sensory characteristics such as taste and flavor. CONSTITUTION: Juice is obtained from Tricholoma matsutake. 3-8%(w/v) Lycium chinense powder and 4-9%(w/v) Taraxacum platycarpum powder are added to Tricholoma matsutake juice. The liquid seasoning comprises Tricholoma matsutake, Lycium chinense, and Taraxacum platycarpum.
Abstract translation: 目的：提供含有松果汁的抗高血压作用的液体调味料，以保持降血压作用，并确保优异的感官特征，如味道和风味。 构成：果汁从马铃薯Tricholoma matsutake获得。 将3-8％（w / v）枸杞子粉末和4-9％（w / v）蒲公英的蒲公英粉末加入到牙龈蓟马汁中。 液体调味料包括Tricholoma matsutake，枸杞和蒲公英。
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