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公开(公告)号：DE59607794D1
公开(公告)日：2001-10-31
申请号：DE59607794
申请日：1996-07-12
Applicant: BASF AG
Inventor： BUSCHMANN ERNST , ZIERKE THOMAS
IPC: C07C231/02 , C07C237/02 , C07K1/06 , C07K1/08 , C07K7/06
Abstract: PCT No. PCT/EP96/03075 Sec. 371 Date Jan. 20, 1998 Sec. 102(e) Date Jan. 20, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05096 PCT Pub. Date Feb. 13, 1997A process for preparing alpha -(N,N-dialkylamino) carboxamides of the formula I where the substituents have the stated meanings, comprises reacting the corresponding free acids with primary or secondary amines in the presence of anhydrides of an alkanephosphonic acid.
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公开(公告)号：AU729333B2
公开(公告)日：2001-02-01
申请号：AU7495796
申请日：1996-10-30
Applicant: BASF AG
Inventor： KLING ANDREAS , JANSSEN BERND , AMBERG WILHELM , HAUPT ANDREAS , RITTER KURT , BUSCHMANN ERNST , BERNARD HARALD , MULLER STEFAN , ZIERKE THOMAS , BARLOZZARI TERESA , ARRUDA MONIKA DE , ROBINSON SIMON
Abstract: Novel peptides of the formulaA-B-D-E-F-L,wherein A, B, D, E, F, and L have the meanings stated in the specification, and their preparation are disclosed. The novel compounds are suitable for controlling diseases.
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公开(公告)号：AU704270B2
公开(公告)日：1999-04-15
申请号：AU6615596
申请日：1996-07-12
Applicant: BASF AG
Inventor： BUSCHMANN ERNST , ZIERKE THOMAS
IPC: C07C231/02 , C07C237/02 , C07K1/06 , C07K1/08 , C07K7/06
Abstract: PCT No. PCT/EP96/03075 Sec. 371 Date Jan. 20, 1998 Sec. 102(e) Date Jan. 20, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05096 PCT Pub. Date Feb. 13, 1997A process for preparing alpha -(N,N-dialkylamino) carboxamides of the formula I where the substituents have the stated meanings, comprises reacting the corresponding free acids with primary or secondary amines in the presence of anhydrides of an alkanephosphonic acid.
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公开(公告)号：HU9802403A2
公开(公告)日：1999-02-01
申请号：HU9802403
申请日：1996-07-12
Applicant: BASF AG
Inventor： BUSCHMANN ERNST , ZIERKE THOMAS
IPC: C07C231/02 , C07C237/02 , C07K1/06 , C07K1/08 , C07K7/06
Abstract: PCT No. PCT/EP96/03075 Sec. 371 Date Jan. 20, 1998 Sec. 102(e) Date Jan. 20, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05096 PCT Pub. Date Feb. 13, 1997A process for preparing alpha -(N,N-dialkylamino) carboxamides of the formula I where the substituents have the stated meanings, comprises reacting the corresponding free acids with primary or secondary amines in the presence of anhydrides of an alkanephosphonic acid.
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公开(公告)号：NO982711A
公开(公告)日：1998-06-12
申请号：NO982711
申请日：1998-06-12
Applicant: BASF AG
Inventor： AMBERG WILHELM , BARLOZZARI TERESA , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , HEGE HANS-GUENTHER , JANSSEN BERND , KLING ANDREAS , LIETZ HELMUT , RITTER KURT , ULLRICH MARTINA , WEYMANN J RGEN , ZIERKE THOMAS
CPC classification number: A61K38/08
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Patent Agency Ranking
公开(公告)号：ZA966371B
公开(公告)日：1998-01-26
申请号：ZA966371
申请日：1996-07-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , RITER KURT , ZIERKE THOMAS
IPC: C07K1/12 , C07K5/06 , C07K1/02 , C07K5/078 , C07K5/08 , C07K5/083 , C07K5/10 , C07K5/103 , C07K7/06 , A61K , C07K
Abstract: PCT No. PCT/EP96/03073 Sec. 371 Date Jan. 13, 1998 Sec. 102(e) Date Jan. 13, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05162 PCT Pub. Date Feb. 13, 1997A process for preparing pentapeptides of the formula I where A and R1-R3 have the stated meanings, comprises assembling the pentapeptide stepwise starting from a prolinamide of the formula II where R1 and R2 have the abovementioned meanings, and eliminating the group -NR1R2 by hydrolysis where appropriate the peptide obtained in this way.
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公开(公告)号：PL321159A1
公开(公告)日：1997-11-24
申请号：PL32115995
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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公开(公告)号：DE59208590D1
公开(公告)日：1997-07-10
申请号：DE59208590
申请日：1992-09-01
Applicant: BASF AG
Inventor： SCHAEFER BERND , BUSCHMANN ERNST , REISSENWEBER GERNOT
IPC: C07C253/10 , C07C253/30 , C07F9/535
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公开(公告)号：SI9520061A
公开(公告)日：1997-06-30
申请号：SI9520061
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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公开(公告)号：CA2237721A1
公开(公告)日：1997-06-26
申请号：CA2237721
申请日：1996-12-11
Applicant: BASF AG
Inventor： BUSCHMANN ERNST , KLING ANDREAS , LIETZ HELMUT , BARLOZZARI TERESA , HEGE HANS-GUENTHER , HAUPT ANDREAS , WEYMANN JUERGEN , JANSSEN BERND , ZIERKE THOMAS , RITTER KURT , BERNARD HARALD , ULLRICH MARTINA , AMBERG WILHELM
IPC: A61K38/00 , A61K31/00 , A61K38/08 , A61P35/00 , A61P35/02 , C07K1/00 , C07K7/06 , A61K38/07 , C07K5/103
Abstract: Novel peptides of the following formula (I): R1R2N-CHX-CO-A-B-D-E-(G)s-K in which R1, R2, A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.
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