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公开(公告)号：KR1020100111288A
公开(公告)日：2010-10-14
申请号：KR1020107017336
申请日：2008-12-03
Applicant: (주)아모레퍼시픽
CPC classification number: A61K38/20 , A23L2/52 , A23L33/105 , A23L33/15 , A23L33/16 , A23L33/40 , A23V2002/00 , A61K8/64 , A61K9/0019 , A61K9/0095 , A61K9/1623 , A61K9/2018 , A61K9/2059 , A61K9/4866 , A61Q19/06 , A23V2200/332
Abstract: PURPOSE: A sliming composition containing interleukin-17(IL-17) is provided to suppress adipocyte differentiation and to reduce lipid level in differentiated adipocyte. CONSTITUTION: A sliming composition contains interleukin-17(IL-17) as an active ingredient. The IL-17 includes IL-17A or IL-17F. The adipocyte is obtained by differentiating mesenchymal stem cell. The composition increases the number or size of lipid droplet inside the adipocytes. The composition is a pharmaceutical, cosmetic or functional composition. The active ingredient is contained in 0.001-100 weight% based on total weight.
Abstract translation: 目的：提供含有白细胞介素-17（IL-17）的减肥组合物以抑制脂肪细胞分化并降低分化脂肪细胞中的脂质水平。 构成：苗条组合物含有白细胞介素-17（IL-17）作为活性成分。 IL-17包括IL-17A或IL-17F。 脂肪细胞通过分化间充质干细胞获得。 该组合物增加脂肪细胞内的脂滴的数量或大小。 组合物是药物，化妆品或功能组合物。 活性成分以总重量计为0.001-100重量％。
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公开(公告)号：KR1020100037832A
公开(公告)日：2010-04-12
申请号：KR1020080097137
申请日：2008-10-02
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/447 , A61K2800/78 , A61Q19/00
Abstract: PURPOSE: A composition containing L-cystathionine, cystathionine or mixture thereof is provided to ensure excellent sliming effect through suppression of adipocyte differentiation. CONSTITUTION: A composition for sliming contains L-cystathionine, cystathionine or mixture thereof as an active ingredient. The composition suppresses adipocyte differentiation. The differentiation of adipocytes is differentiation of mesenchymal stem cells to adipocytes. The composition contains 0.0001-30 weight% of active ingredient based on total weight.
Abstract translation: 目的：提供含有L-胱硫醚，胱硫醚或其混合物的组合物以通过抑制脂肪细胞分化来确保优异的苗条效果。 构成：用于减肥的组合物含有L-胱硫醚，胱硫醚或其混合物作为活性成分。 该组合物抑制脂肪细胞分化。 脂肪细胞的分化是间充质干细胞向脂肪细胞的分化。 该组合物含有0.0001-30重量％的基于总重量的活性成分。
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公开(公告)号：KR1020100018278A
公开(公告)日：2010-02-17
申请号：KR1020080076976
申请日：2008-08-06
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/498 , A61K8/97 , A61K36/232 , A61Q19/08
Abstract: PURPOSE: A cosmetic or pharmaceutical composition containing decursin is provided to enhance the number of epidermal keratinocyte stem cells(KSC) and ensure anti-aging. CONSTITUTION: A composition for proliferating epidermal keratinocyte stem cells contains decursin as an active ingredient. The decursin is obtained from Angelica gigas Nakai ethanol extract or Angelica gigas Nakai supercritical extract. The Angelica gigas Nakai ethanol extract is obtained by adding ethanol, stirring and removing solvent. The Angelica gigas Nakai supercritical extract is obtained by preparing micro powder, and purifying using silica gel column chromatography. A cosmetic composition and a pharmaceutical composition for anti-aging contain a composition containing decursin as an active ingredient.
Abstract translation: 目的：提供含有前胡素的化妆品或药物组合物，以增强表皮角质形成细胞干细胞（KSC）的数量，并确保抗衰老。 构成：用于增殖表皮角化细胞干细胞的组合物含有前胡素作为活性成分。 前胡素是从当归奈加乙醇提取物或当归奈加超临界提取物得到的。 通过加入乙醇，搅拌和除去溶剂获得当归黑加诺乙醇提取物。 通过制备微粉末，使用硅胶柱色谱法纯化得到当归奈加超临界提取物。 化妆品组合物和用于抗衰老的药物组合物含有含有前胡素作为活性成分的组合物。
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公开(公告)号：KR1020100005485A
公开(公告)日：2010-01-15
申请号：KR1020080065534
申请日：2008-07-07
Applicant: (주)아모레퍼시픽
IPC: A61B10/00
Abstract: PURPOSE: A method for measuring skin moisturizing capacity is provided to simply measure skin moisturizing capacity of a candidate material by measuring moisture retention capacity of a green-lentil jelly coated on the candidate material. CONSTITUTION: A green-lentil jelly is spread on a candidate material. The skin moisturizing capacity of the candidate material is evaluated by measuring the skin moisturizing retention of the green-lentil jelly. The evaluation of the skin moisturizing capacity is performed by analyzing an image about the moisture retention capacity of the green-lentil jelly. The moisture retention capacity of the green-lentil jelly is evaluated by measuring the contraction and a curve of the green-lentil jelly. The moisture retention capacity of the green-lentil jelly is in inverse proportion to the contraction and the curve of the moisture retention capacity. The contraction of the green-lentil jelly is measured by evaluating the thickness and the cross section of the green-lentil jelly.
Abstract translation: 目的：提供一种测量皮肤保湿能力的方法，通过测量涂覆在候选材料上的绿扁豆果冻的保湿能力来简单地测量候选材料的皮肤保湿能力。 构成：绿扁豆果冻散布在候选材料上。 通过测量绿扁豆果冻的皮肤保湿保留度来评估候选材料的皮肤保湿能力。 通过分析关于绿扁豆果冻的保湿能力的图像来进行皮肤保湿能力的评价。 通过测量青扁豆果冻的收缩和曲线来评估绿扁豆果冻的保湿能力。 绿扁豆果冻的保湿能力与收缩和保湿能力的曲线成反比。 通过评估绿扁豆果冻的厚度和横截面来测量绿扁豆果冻的收缩。
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65.发明授权3-클로로-5-치환-퀴녹살린-2-아민 유도체 및 약제학적으로허용 가능한 그의 염, 그의 제조방법 및 그를 유효성분으로함유하는 ＳＰＣ 수용체 활성으로 유발되는 염증관련 질환치료제 有权新型3-氯代-5-取代的喹喔啉-2-胺衍生物及其药学上可接受的盐，其制备方法，用于通过含有3-氯代-5-取代的喹喔啉-2-胺衍生物的SPC活性诱导的抗炎性疾病的治疗剂 有效的成分
公开(公告)号：KR100916716B1
公开(公告)日：2009-09-10
申请号：KR1020070097554
申请日：2007-09-27
Inventor： 공영대 , 조희영 , 전문국 , 이태호 , 최길돈 , 공재양 , 박우규 , 황순희 , 김정주 , 이창훈 , 고재영 , 노민수 , 한은실 , 김혁 , 윤준원 , 모주현 , 김도훈
IPC: C07D401/12 , A61K31/498 , A61P29/00
CPC classification number: C07D401/12
Abstract: 본 발명은 하기 화학식 1로 표시되는 3-클로로-5-치환-퀴녹살린-2-아민 유도체 및 약제학적으로 허용 가능한 그의 염, 그의 제조방법 및 그를 유효성분으로 함유하는 SPC 수용체 활성으로 유발되는 염증관련 질환에 유용한 그의 용도에 관한 것이다.
본 발명의 3-클로로-5-치환-퀴녹살린-2-아민 유도체는 사람으로부터 유래된 진피세포 및 마우스를 이용한 동물실험을 통하여 항염증 효과를 검색한 결과, SPC 수용체에 대한 우수한 억제활성을 규명함으로써, 상기 3-클로로-5-치환-퀴녹살린-2-아민 유도체 및 약제학적으로 허용 가능한 그의 염을 유효성분으로 함유하여 SPC 수용체 활성으로 유발되는 아토피성 피부염, 기타 질환에서 나타나는 염증, 소양증 또는 피부 감염증에 유효한 염증관련 질환 치료제로서 유용하게 활용될 수 있다.
(상기 식에서, R
1 및 R
2 는 명세서에서 정의한 바와 같다.)-
Patent Agency Ranking
公开(公告)号：KR101794750B1
公开(公告)日：2017-11-10
申请号：KR1020110094352
申请日：2011-09-20
Applicant: (주)아모레퍼시픽
IPC: A61K36/9066 , C12N5/0775 , A61P17/00
Abstract: 본발명은인간중간엽줄기세포의지방세포로의분화를촉진하는조성물에관한것으로, 보다상세하게는울금추출물을유효성분으로함유하여인간중간엽줄기세포를지방세포로분화하는것을촉진시킴으로써지방체 (Lipid droplet)를생성하여피부의볼륨과탄력을증진시키고주름을개선시키는조성물에관한것이다.
Abstract translation: 因此本发明涉及一种组合物用于促进人类的间充质干细胞的脂肪细胞的分化，由作为活性成分的促进人类干细胞的分化的间充质脂肪细胞，脂肪体（脂质含有更具体地，姜黄提取物 改善皮肤的容量和弹性并改善皱纹。
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公开(公告)号：KR101757734B1
公开(公告)日：2017-07-17
申请号：KR1020100120313
申请日：2010-11-30
Applicant: (주)아모레퍼시픽
Abstract: 본발명은세콰이어캘러스추출물을유효성분으로함유하는지방유래줄기세포의줄기세포성증진용조성물및 피부세포증식용조성물을제공한다. 본발명의세콰이어캘러스추출물을유효성분으로함유하는조성물은지방유래줄기세포재생을촉진시키고표피의재생에관여하는피부표피기저층의전이-증폭세포의증식을촉진시켜, 피부볼륨감을증진시키고손상된피하지방의기능을회복시켜주므로, 피부볼륨감증대용피부미용및 성형용조성물및 피부볼륨감증대용피부외용제조성물에적용가능하다.
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公开(公告)号：KR101753655B1
公开(公告)日：2017-07-06
申请号：KR1020100116411
申请日：2010-11-22
Applicant: (주)아모레퍼시픽
IPC: A61K8/37 , A61K8/368 , A61K8/36 , A61K8/49 , A61K8/89 , A61Q17/04 , A61K31/41 , A61K31/192 , A61K31/215 , A61K31/60
Abstract: 본발명의유효성분으로서신남산유도체, 메톡시페닐아크릴레이트유도체및 β,β-디페닐아크릴레이트유도체를포함하는선스크린용조성물은광 조사시에화학적분해가현저히감소되어광안정성(photo-stability)이향상되고활성이상승되므로광보호성이우수하다.
Abstract translation: 包含本发明活性成分（包括黄原胶衍生物，甲氧基苯基丙烯酸酯衍生物和α，α-二苯基丙烯酸酯衍生物）的防晒组合物显示出光敏性， 光学保护由于偏置和激活而得到改进。
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公开(公告)号：KR101732594B1
公开(公告)日：2017-05-10
申请号：KR1020090075678
申请日：2009-08-17
Applicant: (주)아모레퍼시픽
Abstract: 4',7,8-트리하이드록시이소플라본, 4',6,7-트리하이드록시이소플라본, 및 3',4',7-트리하이드록시이소플라본을포함하는군으로부터선택되는 1 종이상의오르토-디하이드록시이소플라본유도체를유효성분으로함유하는피부재생력향상또는피부탄력개선용조성물이개시된다. 상기조성물은피부각질줄기세포의증식을유도하여, 피부재생력향상또는피부탄력개선효과를나타내며, 이를통해화장품또는의약분야에서다양하게활용가능하다.
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公开(公告)号：KR101663971B1
公开(公告)日：2016-10-12
申请号：KR1020100037969
申请日：2010-04-23
Applicant: (주)아모레퍼시픽
IPC: A61K36/185 , A61K8/97 , A61K9/00 , C12N5/0775
Abstract: 본발명은인간중간엽줄기세포의지방세포로의분화를촉진하는조성물에관한것으로, 보다상세하게는미후도및 미후등추출물중 적어도 1종이상을유효성분으로함유하여인간중간엽줄기세포를지방세포로분화하는것을촉진시킴으로써지방체(Lipid droplet)를생성하여피부의볼륨과탄력을증진시키고주름을개선시키는조성물에관한것이다.
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