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公开(公告)号：KR1020140148227A
公开(公告)日：2014-12-31
申请号：KR1020130071907
申请日：2013-06-21
Applicant: 한림대학교 산학협력단
CPC classification number: A61K8/97 , A61K36/232 , A61K36/258 , A61K36/758 , A61K36/882 , A61K2236/333 , A61K2236/39 , A61K2236/51 , A61Q7/00 , Y10S514/88
Abstract: The present invention relates to a composition for hair growth promotion and hair loss prevention, the composition containing an extract of an herbal complex composed of Scrophularia buergeriana, Glycyrrhiza uralensis Fischer, Korean angelica, Acorus calamus, Cnidium officinale, ginseng, green tea, Persica Semen, Salviae miltiorrhizae, Chinese pepper, and Carthamus tinctorius. In an embodiment of the present invention, the weight ratio of the respective components of the herbal complex composed of Scrophularia buergeriana, Glycyrrhiza uralensis Fischer, Korean angelica, Acorus calamus, Cnidium officinale, ginseng, green tea, Persica Semen, Salviae miltiorrhizae, Chinese pepper, and Carthamus tinctorius is 2.5:1:1:1:1:1:1:1:1:1:1. In addition, the purpose of the present invention is to provide a novel preparation method wherein an effective extract is obtained from the herbal complex composed of Scrophularia buergeriana, Glycyrrhiza uralensis Fischer, Korean angelica, Acorus calamus, Cnidium officinale, ginseng, green tea, Persica Semen, Salviae miltiorrhizae, Chinese pepper, and Carthamus tinctorius.
Abstract translation: 本发明涉及一种用于头发生长促进和脱发预防的组合物，该组合物含有由玄参，甘草，义肯，韩国当归，菖蒲，芫荽，人参，绿茶，Persica Semen ，丹参，中国胡椒和红花。 在本发明的一个实施方案中，由玄参，甘草，韩国当归，菖蒲，芫荽，人参，绿茶，柿子，丹参，胡椒粉组成的草本复合物各成分的重量比 ，Carthamus tinctorius为2.5：1：1：1：1：1：1：1：1：1。 另外，本发明的目的是提供一种新颖的制备方法，其中有效提取物是从由玄参，甘草，费肯，韩国当归，菖蒲，芫荽，人参，绿茶，Persica 精液，丹参，辣椒和红花。
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公开(公告)号：KR1020140094845A
公开(公告)日：2014-07-31
申请号：KR1020130007400
申请日：2013-01-23
Applicant: 한림대학교 산학협력단
IPC: A23L33/155 , A23L1/28 , A23G1/00
CPC classification number: A23L33/155 , A23G1/32 , A23L33/10 , A23L33/105 , C12N1/14
Abstract: According to the present invention, a food composition for vitamin D intake: includes a vitamin D precursor extract and chocolate; does not have side effects caused by pharmacological administration; can be absorbed into a human body very well. The vitamin D precursor extract includes a mushroom extract, which is selected from a group, constituted by shiitake mushrooms, oyster mushrooms, enoki mushrooms, button mushrooms, black mushrooms, manna lichens, Coriolus versicolor, lingzhi mushroom, and a mixture of those.
Abstract translation: 根据本发明，维生素D摄入食品组合物包括维生素D前体提取物和巧克力; 没有药理作用引起的副作用; 可以很好地吸收到人体内。 维生素D前体提取物包括蘑菇提取物，其由香菇，蚝蘑，香菇，纽扣蘑菇，黑蘑菇，甘露地衣，Coriolus versicolor，灵芝蘑菇及其混合物组成的组中选出。
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公开(公告)号：KR1020130138569A
公开(公告)日：2013-12-19
申请号：KR1020120062261
申请日：2012-06-11
Applicant: 한림대학교 산학협력단 , (주)프론트바이오
IPC: A61K36/28 , A61K31/192 , A61K31/19 , A61K31/216
CPC classification number: A61K31/216 , A61K36/28 , Y10S514/824 , Y10S514/866 , Y10S514/912
Abstract: The present invention relates to a use of xanthium fruit extract and/or dicaffeoyl quinic acid derivatives for preventing, curing, and/or treating a diabetes induced complication, more specifically a medicinal composition or a food composition containing more than one material selected from the group consisting of a xanthium fruit extract and a dicaffeoyl quinic acid derivative denoted by chemical formula 1 as active ingredients. The composition has excellent antioxidant activity, aldose reductase suppression activity, and final saccharified product suppression activity, has almost no problems related to side effects and safety by using natural extracts, and is capable of being used for curing, preventing, and treating a diabetes induced complication.
Abstract translation: 本发明涉及一种用于预防，治愈和/或治疗糖尿病并发症的黄素果实提取物和/或二草酰奎尼酸衍生物的用途，更具体地说，涉及一种药物组合物或含有多于一种选自下组的材料的食品组合物 由化学式1表示的苍耳果提取物和二菌酸奎酸衍生物作为活性成分组成。 该组合物具有优异的抗氧化活性，醛糖还原酶抑制活性和最终的糖化产物抑制活性，几乎没有通过使用天然提取物与副作用和安全性相关的问题，并且能够用于治疗，预防和治疗糖尿病诱导 并发症。
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公开(公告)号：KR1020130088333A
公开(公告)日：2013-08-08
申请号：KR1020120009503
申请日：2012-01-31
Applicant: 한림대학교 산학협력단
IPC: A61K36/734 , A61K36/17 , A61K36/60 , A61K36/28
CPC classification number: A61K36/734 , A61K36/17 , A61K36/60 , A61Q7/00 , Y10S514/859 , Y10S514/864
Abstract: PURPOSE: A composition for suppressing testosterone 5-alpha reductase is provided to effectively suppress testosterone 5-alpha reductase with safety and little side effects. CONSTITUTION: A composition for suppressing testosterone 5-alpha reductase contains one or more extracts selected among a Crataegus pinnatifida extract, an Ephedra sinica extract, a Morus bombycis extract, an Acer tegmentosum extract, a Nelumbo nucifera extract, and a Siegesbeckia glabrescens extract as active ingredients. A pharmaceutical composition for preventing or treating male hormone dependent diseases contains the extracts as active ingredients.
Abstract translation: 目的：提供抑制睾酮5-α还原酶的组合物，以有效抑制睾酮5-α还原酶的安全性和副作用。 构成：用于抑制睾酮5-α还原酶的组合物含有一种或多种提取物，其选自Crataegus pinnatifida提取物，麻黄提取物，Morus bombycis提取物，Acer tegmentosum提取物，Nelumbo Nucifera提取物和作为活性的Siegesbeckia glabrescens提取物 配料。 用于预防或治疗雄性激素依赖性疾病的药物组合物含有作为活性成分的提取物。
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65.发明授权현초 추출물 또는 이의 분획물을 유효성분으로 포함하는 당뇨병 합병증의 예방 또는 치료용 조성물 有权包含来自GUNANIUM THUNBERGII的提取物的组合物，用于预防或治疗各种糖尿病并发症
公开(公告)号：KR101276293B1
公开(公告)日：2013-06-24
申请号：KR1020110062851
申请日：2011-06-28
Applicant: 한림대학교 산학협력단
IPC: A61K36/185 , A61P3/10 , A61P3/00
Abstract: 본 발명은 부작용 또는 독성 등의 우려가 없고 알도스 환원효소 억제활성 및 최종당화산물생성 억제활성이 뛰어난 효과가 있는 현초 추출물 또는 이의 분획물을 유효성분으로 포함하는 당뇨병 합병증의 예방 또는 치료용 조성물에 관한 것이다.
보다 구체적으로 본 발명에 따라 알도스 환원효소 억제, 갈락티톨 생성 억제, 및 최종당화산물 생성 억제 효과가 뛰어난 현초 추출물 및 이의 분획물, 상기 현초 추출물 또는 이의 분획물을 유효성분으로 포함하는 당뇨병 합병증의 예방 또는 치료용 조성물이 제공된다. 상기 현초 추출물 및/또는 이의 분획물을 유효성분으로 포함하는 당뇨병 합병증의 예방 또는 치료용 조성물은 복부팽만감, 구역감, 설사, 저혈당 유발 등의 원치 않는 부작용 내지 독성의 우려 없이 당뇨병 합병증의 예방 또는 치료를 위해 유용하게 사용될 수 있다.-
Patent Agency Ranking
公开(公告)号：KR1020130010942A
公开(公告)日：2013-01-30
申请号：KR1020110071744
申请日：2011-07-20
Applicant: 한림대학교 산학협력단
IPC: A61K36/882 , A61P19/10 , A61P19/00
Abstract: PURPOSE: A composition containing a yellow flag iris extract for preventing and treating osteoporosis is provided to suppress TRAP activity of osteoclast and bone absorption and to promote osteogenesis. CONSTITUTION: A composition for preventing and treating osteoporosis contains 0.001-5 % of a yellow flag iris extract as an active ingredient. The extract is prepared by mixing yellow flag iris with water, alcohol, acetone, hexane, ethyl acetate, or a mixture thereof, heating at 60-70 deg.C., filtering and concentrating the extract, and freeze-drying the extract. The composition enhances alkaline phosphatase activity and promotes calcification.
Abstract translation: 目的：提供含有用于预防和治疗骨质疏松症的黄旗虹膜提取物的组合物，以抑制破骨细胞和骨吸收的TRAP活性并促进成骨。 构成：用于预防和治疗骨质疏松症的组合物含有0.001-5％的黄旗虹膜提取物作为活性成分。 通过将黄旗虹膜与水，醇，丙酮，己烷，乙酸乙酯或其混合物混合，在60-70℃加热，过滤并浓缩提取物，并将提取物冷冻干燥，制备提取物。 该组合物增强碱性磷酸酶活性并促进钙化。
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公开(公告)号：KR1020130010941A
公开(公告)日：2013-01-30
申请号：KR1020110071743
申请日：2011-07-20
Applicant: 한림대학교 산학협력단
CPC classification number: A61K36/537 , A61K2236/331 , A61K2236/333 , A61K2236/35 , A61K2236/51 , Y10S514/824
Abstract: PURPOSE: A composition containing a Salvia plebeia R.Br extract for preventing and treating atherosclerosis is provided to reduce foam cell formation and to promote the release of cholesterol to the outside. CONSTITUTION: A composition for preventing and treating atherosclerosis contains a Salvia plebeia R. Br. extract as an active ingredient. The extract is prepared by mixing water, alcohol, acetone, hexane, ethyl acetate, or a mixture thereof with Salvia plebeia R. Br. and heating at 60-70 deg.C. for 3-5 hours; a step of filtering and concentrating; and a step of freeze-drying.
Abstract translation: 目的：提供含有用于预防和治疗动脉粥样硬化的Salvia plebia R.Br提取物的组合物以减少泡沫细胞的形成并促进胆固醇向外部的释放。 构成：用于预防和治疗动脉粥样硬化的组合物含有Salvia plebia R.Br。 提取物作为活性成分。 通过将水，醇，丙酮，己烷，乙酸乙酯或其与Salvia plebeia R.Br的混合物混合来制备提取物。 并在60-70℃加热。 3-5小时; 过滤和集中的一个步骤; 和冷冻干燥步骤。
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68.发明公开
公开(公告)号：KR1020120119561A
公开(公告)日：2012-10-31
申请号：KR1020110037572
申请日：2011-04-22
Applicant: 한림대학교 산학협력단
CPC classification number: A61K47/64 , A23L33/17 , A61K8/64 , A61K47/22 , Y10S514/824 , Y10S514/885 , Y10S514/886
Abstract: PURPOSE: An increase method of fused protein into living cells or organs by adding levosulpiride to fused protein in which protein transport domains and therapeutic protein are covalently bonded is provided to increase therapeutic effects of protein medicines for various diseases. CONSTITUTION: An increase method of fused protein into living cells or organs is processed by adding levosulpiride to fused protein in which protein transport domains and therapeutic protein are covalently bonded. The levosulpiride is primarily processed in the living cells or organs than the fused protein. A protein transport domain is Tat, PEP-1, oligolysine, oligo arginine or oligo(lysine and arginine). The therapeutic protein is rpS3. A composition for preventing and treating inflammatory diseases comprises fused proteins in which is covalently bonded with the protein transport domain and levosulpiride. The inflammation therapeutic protein is rpS3. A composition for preventing and improving skin external application comprises fused proteins in which is covalently bonded with the protein transport domain and levosulpiride.
Abstract translation: 目的：提供蛋白质转运区域和治疗性蛋白质共价键合的融合蛋白中的左半乳糖苷加入活细胞或器官中的融合蛋白的增加方法，以增加蛋白质药物对各种疾病的治疗效果。 构成：将融合蛋白加入到活细胞或器官中的增加方法是通过将蛋白质转运结构域和治疗性蛋白质共价结合的融合蛋白中加入左美沙比来进行加工。 左氧氟沙棱主要在活体细胞或器官中处理，而不是融合蛋白。 蛋白质转运结构域是Tat，PEP-1，寡聚赖氨酸，寡聚精氨酸或寡聚（赖氨酸和精氨酸）。 治疗性蛋白质是rpS3。 用于预防和治疗炎性疾病的组合物包括其中与蛋白质转运结构域和左旋舒巴比妥共价键合的融合蛋白。 炎症治疗蛋白是rpS3。 用于预防和改善皮肤外用的组合物包括其中与蛋白质转运结构域和左旋肉碱共价结合的融合蛋白。
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公开(公告)号：KR101185901B1
公开(公告)日：2012-09-25
申请号：KR1020100012585
申请日：2010-02-10
Applicant: 한림대학교 산학협력단
Abstract: 본 발명은 등골나물 추출물을 유효성분으로 포함하는 약학 조성물에 관한 것이다. 상기 등골나물 추출물은 암세포를 이용하여 측정한 항암효과 즉, 암세포에 대한 세포사멸 효과가 있고, 암전이 저해 효과가 우수한 것으로 확인되었을 뿐만 아니라, 천연물 추출물이므로 부작용과 안전성 관련 문제가 거의 없고 실험결과 세포 독성도 없으므로, 이를 유효성분으로 포함하는 상기 약학 조성물은 암을 치료, 예방 또는 개선하기 위하여 사용될 수 있다.
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公开(公告)号：KR101174074B1
公开(公告)日：2012-08-14
申请号：KR1020100043080
申请日：2010-05-07
Applicant: 한림대학교 산학협력단
IPC: A61K36/484 , A61K31/352 , A61P35/00 , A23L1/30
Abstract: 감초의 유기 용매 추출물, 이의 분획물 및 이로부터 분리된 화합물의 항암 및/또는 암전이 억제에 있어서의 신규한 용도가 제공된다. 즉, 감초의 유기 용매 추출물, 이의 분획물 및 이로부터 분리된 화합물로 이루어진 군에서 선택된 1종 이상을 포함하는 항암 및/또는 암전이 억제용 조성물이 제공된다.
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