公开(公告)号：HU213384B

公开(公告)日：1997-05-28

申请号：HU9400743

申请日：1992-09-01

Applicant: BASF AG

Inventor： BUSCHMANN ERNST ,  REISSENWEBER GERNOT ,  SCHAEFER BERND

IPC: C07C253/10 ,  C07C253/30 ,  C07F9/535

公开(公告)号：FI964446A

公开(公告)日：1997-01-03

申请号：FI964446

申请日：1996-11-05

Applicant: BASF AG

Inventor： AMBERG WILHELM ,  BERNARD HARALD ,  BUSCHMANN ERNST ,  HAUPT ANDREAS ,  JANITSCHKE LOTHAR ,  JANSSEN BERND ,  KARL ULRICH ,  KLING ANDREAS ,  MUELLER STEFAN ,  DE POTZOLLI BERND ,  RITTER KURT ,  THYES MARCO ,  ZIERKE THOMAS

IPC: A61K38/00 ,  A61P35/00 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06 ,  C07K

Abstract: Compounds of the formulawhere R1, R2, R3 and R4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.

公开(公告)号：FI964448A0

公开(公告)日：1996-11-05

申请号：FI964448

申请日：1996-11-05

Applicant: BASF AG

Inventor： AMBERG WILHELM ,  BERNARD HARALD ,  BUSCHMANN ERNST ,  HAUPT ANDREAS ,  JANITSCHKE LOTHAR ,  JANSSEN BERND ,  KARL ULRICH ,  KLING ANDREAS ,  MUELLER STEFAN ,  DE POTZOLLI BERND ,  RITTER KURT ,  THYES MARCO ,  ZIERKE THOMAS

IPC: A61K38/08 ,  A61K38/00 ,  A61P35/00 ,  C07K1/08 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06 ,  C07K14/52 ,  C07K

Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.

公开(公告)号：ZA953584B

公开(公告)日：1996-11-04

申请号：ZA953584

申请日：1995-05-04

Applicant: BASF AG

Inventor： BUSCHMANN ERNST ,  AMBERG WILHELM ,  BERNARD HARALD ,  HAUPT ANDREAS ,  JANSSEN BERND ,  KARL ULRICH ,  KLING ANDREAS ,  MUELLER STEFAN ,  JANITSCHKE LOTHAR ,  RITTER KURT ,  THYES MARCO ,  ZIERKE THOMAS ,  POTZOLLI BERND DE

IPC: A61K38/08 ,  A61P35/00 ,  A61K38/00 ,  C07K1/08 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06 ,  C07K14/52 ,  C07K ,  A61K

Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.

公开(公告)号：ES2081132T3

公开(公告)日：1996-02-16

申请号：ES92920403

申请日：1992-09-24

Applicant: BASF AG

Inventor： KLEIN ULRICH ,  NEUMANN ULRICH ,  MACKENROTH WOLFGANG ,  RENZ GUENTER ,  KRIEG WOLFGANG ,  MACKENROTH CHRISTIANE ,  BUSCHMANN ERNST ,  DE KRAMER JACOBUS JAN ,  MILLI ROLAND

IPC: C07C29/10 ,  A01N31/04 ,  A01N49/00 ,  C07C29/60 ,  C07C29/62 ,  C07C33/02 ,  C07C41/48 ,  C07C41/54 ,  C07C43/178 ,  C07C43/313 ,  C07C43/315

公开(公告)号：AT131806T

公开(公告)日：1996-01-15

申请号：AT92920403

申请日：1992-09-24

Applicant: BASF AG

Inventor： KLEIN ULRICH ,  NEUMANN ULRICH ,  MACKENROTH WOLFGANG ,  RENZ GUENTER ,  KRIEG WOLFGANG ,  MACKENROTH CHRISTIANE ,  BUSCHMANN ERNST ,  DE KRAMER JACOBUS JAN ,  MILLI ROLAND

IPC: C07C29/10 ,  A01N31/04 ,  A01N49/00 ,  C07C29/60 ,  C07C29/62 ,  C07C33/02 ,  C07C41/48 ,  C07C41/54 ,  C07C43/178 ,  C07C43/313 ,  C07C43/315

公开(公告)号：CA2168457A1

公开(公告)日：1995-02-09

申请号：CA2168457

申请日：1994-07-08

Applicant: BASF AG

Inventor： KLEIN ULRICH ,  BUSCHMANN ERNST ,  KEIL MICHAEL ,  GOETZ NORBERT ,  HARREUS ALBRECHT

IPC: C07C239/20 ,  C07D333/20 ,  C07D207/335 ,  C07D307/52

Abstract: In order to prepare O-substituted hydroxylammonium salts having formula (I): R1-CHX-O-NH2 . HL, in which L = halogen, hydrogen sulphate; X = H, alkyl R1 = possibly substituted phenyl, thienyl, furanyl, pyrrolyl or -CR2=CR3R4, in which R2, R3, R4 = H, halogen or alkyl, an acetonoxime-O-alkyl or acetonoxime-O-benzyl ether having formula (II) is reacted with water and a mineral acid H-L while the resulting acetone is continuously removed, and hydrolysis is intermittently carried out at 0-50 .degree.C and under 10-500 mbar pressure. The O-substituted hydroxylammonium salts having the formula (I) are intermediate products for plant protective agents and pharmaceuticals.

公开(公告)号：ZA9208195B

公开(公告)日：1994-04-25

申请号：ZA9208195

申请日：1992-10-23

Applicant: BASF AG

Inventor： KLEIN ULRICH ,  NEUMANN ULRICH ,  MACKENROTH WOLFGANG ,  RENZ GUENTER ,  KRIEG WOLFGANG ,  MACKENROTH CHRISTIANE ,  BUSCHMANN ERNST ,  DEKRAMER JACOBUS JAN ,  MILLI ROLAND

IPC: C07C29/10 ,  A01N31/04 ,  A01N49/00 ,  C07C33/02 ,  C07C43/178 ,  C07C43/313 ,  C07C43/315 ,  C07C ,  A01N

CPC classification number: C07C33/02 ,  C07C43/313 ,  C07C43/315 ,  Y02P20/55

公开(公告)号：HU9302798D0

公开(公告)日：1994-01-28

申请号：HU9302798

申请日：1993-10-04

Applicant: BASF AG

Inventor： KLEIN ULRICH ,  BUSCHMANN ERNST ,  KEIL MICHAEL ,  GOETZ NORBERT ,  HARTMANN HORST

IPC: C07C239/20

Abstract: O-Substituted hydroxylammonium salts are prepared by hydrolysis of acetone oxime ethers with acid in the presence of an additive and removal of acetone and water by distillation with the aid of the additive.

公开(公告)号：CA2121250A1

公开(公告)日：1993-04-29

申请号：CA2121250

申请日：1992-09-24

Applicant: BASF AG

Inventor： KLEIN ULRICH ,  NEUMANN ULRICH ,  MACKENROTH WOLFGANG ,  RENZ GUENTER ,  KRIEG WOLFGANG ,  MACKENROTH CHRISTIANE ,  BUSCHMANN ERNST ,  DEKRAMER JACOBUS J ,  MILLI ROLAND ,  DEKRAMER JACOBUS J

IPC: C07C29/10 ,  A01N31/04 ,  A01N49/00 ,  C07C29/60 ,  C07C29/62 ,  C07C33/02 ,  C07C41/48 ,  C07C41/54 ,  C07C43/178 ,  C07C43/313 ,  C07C43/315 ,  A01N31/02

Abstract: A process is disclosed for preparing a mixture of 8E,10E-dodecadienol (Ia), 8E,10Z-dodecadienol (Ib), 8Z,10E-dodecadie- nol (Ic) and 8Z,10Z-dodecadienol (Id), H3C-CH=CH-CH=CH-(CH2)6-CH2-OH, (8E,10 E = Ia), (8E,10Z = Ib), (8Z,10E = Ic), (8Z,10Z = Id) from 1,8-octandiol (II) which is transformed by a halogenating agent into (III): Hal- CH2-(CH2)6-CH2-OH, (III) is then reacted with (IV): H2C = CH-O-R, producing (V): Hal-CH2-(CH2)6-CH2-O- CH(CH3)-OR, which is transformed in the presence of magnesium with crotonaldehyde into (VI): H3C-CH = CH- CH(OH)-(CH2)8-O-CH(CH3)-OR. The alcohol protective group is split off from (VI) in the presence of an acid, at the same time as the hydroxyl function is eliminated. Also disclosed are intermediate s for this process, and a process for fighting the fruit surface eating tortrix moth Cydia pomonella with this mixture accordin g to the mating interruption method.