公开(公告)号：AU6610086A

公开(公告)日：1987-06-11

申请号：AU6610086

申请日：1986-12-04

Applicant: BASF AG

Inventor： SEITZ WERNER ,  BALDINGER VERENA ,  GRIES JOSEF ,  LENKE DIETER ,  RASCHAK MANFRED ,  RUEBSAMEN KLAUS

IPC: A61K31/135 ,  A61P1/04 ,  A61P9/00 ,  A61P9/12 ,  C07C223/02 ,  C07D317/58 ,  C07D319/18 ,  C07D325/00 ,  C07C95/08 ,  C07D319/08

公开(公告)号：DK149888C

公开(公告)日：1987-05-04

申请号：DK59281

申请日：1981-02-12

Applicant: BASF AG

Inventor： THIEME PETER C ,  FRANKE ALBRECHT ,  LENKE DIETER ,  LEHMANN HANS DIETER ,  GRIES JOSEF

IPC: C07D413/12 ,  A61K31/495 ,  A61K31/496 ,  A61P9/12 ,  C07D271/10 ,  C07D405/12

Abstract: Novel phenylpiperazinylpropanols of 1,3,4-oxadiazolylphenols and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and are useful in the treatment of hypertonia.

公开(公告)号：DK149590B

公开(公告)日：1986-08-04

申请号：DK532679

申请日：1979-12-14

Applicant: BASF AG

Inventor： THYES MARCO ,  GRIES JOSEF ,  LEHMANN HANS DIETER ,  KUNZE JOHANNES ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/395 ,  A61K31/502 ,  A61P7/02 ,  A61P9/12 ,  C07C62/38 ,  C07C205/56 ,  C07D231/54 ,  C07D237/26 ,  C07D403/10

Abstract: 2-Aryl-3,4-diaza-bicyclo-[4.1.0]hept-2-en-5-ones, substituted in the phenyl ring, of the general formula their preparation, and therapeutic agents, containing these compounds, which may be used for the treatment of hypertension or of thrombo-embolic disorders.

公开(公告)号：PH19739A

公开(公告)日：1986-06-23

申请号：PH27104

申请日：1982-04-06

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETZSCHMAR ROLF ,  LEHMANN HANS DIETER ,  FRIEDRICH LUDWIG ,  TREIBER HANS JOERG ,  WUPPERMAN DIRK ,  SIMMERMANN FRANK ,  SEITZ WERNER ,  DENGEL FERDINAND ,  FRANK WOLFRAM ,  KURBJUWELT HANS GEORG ,  MUELLER CLAUS D

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18

公开(公告)号：NO852793L

公开(公告)日：1986-01-13

申请号：NO852793

申请日：1985-07-11

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ ,  SCHMIED BERNHARD ,  RASCHACK MANFRED ,  LEHMANN HANS-DIETER ,  GRIES JOSEF ,  RUEBSAMEN KLAUS

IPC: A61K31/50 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D237/00 ,  C07D403/04 ,  C07D403/10 ,  C07D

Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula I their preparation and their use in the treatment of disorders.

公开(公告)号：DK148536C

公开(公告)日：1986-01-06

申请号：DK257481

申请日：1981-06-12

Applicant: BASF AG

Inventor： THYES MARCO ,  FRANKE ALBRECHT ,  KOENIG HORST ,  LENKE DIETER ,  LEHMANN HANS DIETER ,  GRIES JOSEF

IPC: A61K31/50 ,  C07D237/04

Abstract: Novel 6-phenyl-4,5-dihydro-3(2H)-pyridazinones which are substituted in the p-position of the phenyl ring by a carbamate or thiocarbamate group, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in thrombo-embolic disorders, and as anti-hypertensives.

公开(公告)号：CS238635B2

公开(公告)日：1985-12-16

申请号：CS783882

申请日：1982-04-06

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETZSCHMAR ROLF ,  LEHMANN HANS D ,  FRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER ,  TREIBER HANS J ,  DENGEL FERDINAND ,  FRANK WOLFRAM ,  KURBJUWEIT HANS-GEORG ,  MUELLER CLAUS D

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18 ,  C07C121/66

公开(公告)号：AU546383B2

公开(公告)日：1985-08-29

申请号：AU8249082

申请日：1982-04-08

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETZSCHMAR ROLF ,  LEHMANN HANS DIETER ,  FRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER ,  TREIBER HANS GEORG ,  DENGEL FERDINAND ,  FRANK WOLFRAM ,  KURBJUWEIT HANS-GEORG ,  MUELLER CLAUS D

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18 ,  C07C121/78

公开(公告)号：NO844778L

公开(公告)日：1985-06-03

申请号：NO844778

申请日：1984-11-30

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  SPIEGLER WOLFGANG ,  SIEGEL HARDO ,  MUELLER CLAUS D ,  PHILIPSBORN GERDA VON ,  LENKE DIETER ,  GRIES JOSEF

IPC: A61K31/34 ,  A61K31/341 ,  A61K31/38 ,  A61K31/381 ,  A61K31/40 ,  A61K31/41 ,  A61K31/415 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/4418 ,  A61K31/495 ,  A61P9/06 ,  C07D207/32 ,  C07D207/333 ,  C07D213/50 ,  C07D231/12 ,  C07D307/46 ,  C07D333/22 ,  C07D409/12 ,  C07D

公开(公告)号：CA1187878A

公开(公告)日：1985-05-28

申请号：CA394179

申请日：1982-01-14

Applicant: BASF AG

Inventor： THIEME PETER C ,  STEINER GERD ,  ROHR WOLFGANG ,  LENKE DIETER ,  GRIES JOSEF ,  WEIFENBACH HARALD ,  TESCHENDORF HANS-JUERGEN ,  HOFMANN HANS P ,  KREISKOTT HORST

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/495 ,  A61K31/496 ,  A61P9/02 ,  A61P11/00 ,  A61P25/20 ,  C07D231/12 ,  C07D233/60 ,  C07D233/61 ,  C07D271/10 ,  C07D295/06 ,  C07D295/067 ,  C07D295/096 ,  C07D521/00 ,  C07D295/04 ,  C07D403/12

Abstract: Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.