公开(公告)号：AU2003206964A8

公开(公告)日：2003-09-16

申请号：AU2003206964

申请日：2003-02-28

Applicant: BASF AG

Inventor： ALTHOFER HENNING

IPC: A01H5/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12N15/52 ,  C12N15/80 ,  C12P25/00 ,  C12R1/15 ,  C12R1/645 ,  C12R1/865 ,  C12N15/79 ,  C12N15/74 ,  C12N1/20 ,  C12N1/14 ,  C12N15/11

Abstract: The invention relates to transcription terminators, to an organism containing at least one of these transcription terminators, and to a method for producing riboflavin. According to the invention, an organism is grown, which is capable of producing riboflavin and has at least one of these transcription terminators, whereby the respective transcription terminator is operatively linked to at least one rib gene.

公开(公告)号：AU2003206964A1

公开(公告)日：2003-09-16

申请号：AU2003206964

申请日：2003-02-28

Applicant: BASF AG

Inventor： ALTHOFER HENNING

IPC: A01H5/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12N15/52 ,  C12N15/80 ,  C12P25/00 ,  C12R1/15 ,  C12R1/645 ,  C12R1/865

Abstract: The invention relates to transcription terminators, to an organism containing at least one of these transcription terminators, and to a method for producing riboflavin. According to the invention, an organism is grown, which is capable of producing riboflavin and has at least one of these transcription terminators, whereby the respective transcription terminator is operatively linked to at least one rib gene.

公开(公告)号：AU2003270098A8

公开(公告)日：2004-03-29

申请号：AU2003270098

申请日：2003-08-23

Applicant: BASF AG

Inventor： ROHL FRANZ ,  FREUND ANNETTE ,  KAROS MARVIN ,  LACOUR THIERRY ,  ALTHOFER HENNING ,  KAESLER BRUNO

IPC: A01N43/90 ,  A01N61/00 ,  C12N9/78 ,  C12N15/04 ,  C12N15/52 ,  C12Q1/32 ,  C12Q1/34

Abstract: The present invention relates to methods for determining GTP Cyclohydrolase I or II activity in a sample.

公开(公告)号：AU2003270098A1

公开(公告)日：2004-03-29

申请号：AU2003270098

申请日：2003-08-23

Applicant: BASF AG

Inventor： LACOUR THIERRY ,  FREUND ANNETTE ,  ROHL FRANZ ,  ALTHOFER HENNING ,  KAROS MARVIN ,  KAESLER BRUNO

IPC: A01N43/90 ,  A01N61/00 ,  C12N9/78 ,  C12N15/04 ,  C12N15/52 ,  C12Q1/32 ,  C12Q1/34

Abstract: The present invention relates to methods for determining GTP Cyclohydrolase I or II activity in a sample.

公开(公告)号：AU6291698A

公开(公告)日：1998-07-31

申请号：AU6291698

申请日：1997-12-29

Applicant: BASF AG

Inventor： ALTMANN-JOHL REGULA ,  PHILIPPSEN PETER ,  ALTHOFER HENNING ,  SEULBERGER HARALD

IPC: C12N15/09 ,  C07K14/37 ,  C12N1/15 ,  C12N9/02 ,  C12N9/04 ,  C12N9/10 ,  C12N9/88 ,  C12N15/00 ,  C12N15/31 ,  C12N15/60 ,  C12P25/00 ,  C12Q1/18 ,  C12Q1/68 ,  C12R1/645 ,  C12R1/865

Abstract: The present invention relates to the terminal sequencing of random genomic fragments performed with the filamentous fungus A.gossypii, to the sequences obtained therewith and the use of the sequences for forensic identification, to characterize genes and gene organization of this ascomycete by inter-genomic comparison, to identify biosynthetic genes that can be used as selection markers, to isolate promotors and terminators for application in a homologous as well as heterologous context, to find putative centromere containing clones, chromosome mapping, chromosome identifying, general information about chromosome organization and in addition to identify ORF containing SRS sequences with no homology to S. cerevisiae or any other organism which allows the identification of A. gossypii specific genes.

公开(公告)号：AU2002333696A1

公开(公告)日：2003-03-10

申请号：AU2002333696

申请日：2002-08-23

Applicant: BASF AG

Inventor： KROGER BURKHARD ,  DOVAL JOSE L REVUELTA ,  ALTHOFER HENNING ,  KAROS MARVIN

IPC: C12N15/09 ,  C07K16/40 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/00 ,  C12N15/31 ,  C12P25/00 ,  C12Q1/68 ,  C12N15/52 ,  C12N15/81 ,  C12Q1/25

Abstract: The present invention relates to novel polynucleotides from Ashbya gossypii; to oligonucleotides hybridizing therewith; to expression cassettes and vectors which comprise these polynudeotides; to microorganisms transformed therewith; to polypeptides encoded by these polynucleotides; and to the use of the novel polypeptides and polynucleotides as targets for modulating the metabolic reactions and, in particular, improving vitamin B2 production in microorganisms of the genus Ashbya.

公开(公告)号：AU2002327839A1

公开(公告)日：2003-03-10

申请号：AU2002327839

申请日：2002-08-21

Applicant: BASF AG

Inventor： KAROS MARVIN ,  KROGER BURKHARD ,  DOVAL JOSE L REVUELTA ,  ALTHOFER HENNING

IPC: C12N15/09 ,  A61K31/7052 ,  A61K38/00 ,  A61P43/00 ,  C07K14/37 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12P19/32 ,  C12Q1/02 ,  C12N15/11 ,  C12N15/63

Abstract: The invention relates to novel polynucleotides from Ashbya gossypii; to oligonucleotides hybridizing therewith; to expression cassettes and vectors which comprise these polynucleotides; to microorganisms transformed therewith; to polypeptides encoded by these polynucleotides; and to the use of the novel polypeptides and polynucleotides as targets for modulating the properties of the cell wall or of the cytoskeleton and, in particular, improving vitamin B2 production in microorganisms of the genus Ashbya.

公开(公告)号：AU1223502A

公开(公告)日：2002-03-26

申请号：AU1223502

申请日：2001-09-13

Applicant: BASF AG

Inventor： ALTHOFER HENNING ,  DOVAL JOSE L REVUELTA ,  SANTOS MARIA

IPC: C07K14/37 ,  C12N15/31 ,  C12N5/10 ,  C12N15/80

公开(公告)号：AU4140999A

公开(公告)日：1999-12-13

申请号：AU4140999

申请日：1999-05-10

Applicant: BASF AG

Inventor： ALTHOFER HENNING ,  SEULBERGER HARALD ,  ZELDER OSKAR ,  DOVAL JOSE LUIS REVUELTA

IPC: C12N15/09 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/54 ,  C12N15/80 ,  C12P25/00 ,  C12N15/52

Abstract: The invention relates to a genetic method for producing riboflavin. The production of riboflavin in organisms is increased by specially selecting genes of the riboflavin biosynthesis or of the combination thereof in organisms, especially in bacteria, fungi, yeasts and plants, and of the expression thereof. The invention also relates to a nucleic acid fragment containing genes with the sequences SEQ ID No. 1, SEQ ID No. 3 or SEQ ID No. 5 or the functional equivalents thereof, to expression vectors containing the nucleic acid fragments, and to organisms containing at least one nucleic acid fragment or at least one vector.

公开(公告)号：CA2521288A1

公开(公告)日：2004-10-21

申请号：CA2521288

申请日：2004-04-06

Applicant: BASF AG

Inventor： KESSELER MARIA ,  ALTHOFER HENNING

IPC: C12N9/04 ,  C12N15/53 ,  C12P7/04 ,  C12P13/00 ,  C12P17/00 ,  C12P41/00 ,  C07D333/20

Abstract: The invention relates to proteins that have an enzymatic activity for reduci ng substituted alkanones, such as 3-methylamino-1-(2-thienyl)-propane-1-on. The invention also relates to nucleic acids that encode these proteins, to nucle ic acid constructs, vectors, genetically modified microorganisms and to methods for producing substituted (S) alkanols, such as for example (S)-3-methylamin o- 1-(2-thienyl)-(S)-propanol.