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公开(公告)号:CZ184698A3
公开(公告)日:1998-09-16
申请号:CZ184698
申请日:1996-12-11
Applicant: BASF AG
Inventor: AMBERG WILHELM DR , BARLOZZARI TERESA , BERNARD HARALD DR , BUSCHMANN ERNST DR , HAUPT ANDREAS DR , HEGE HANS-GUENTHER DR , JANSSEN BERND DR , KLING ANDREAS DR , LIETZ HELMUT , RITTER KURT DR , ULRICH MARTINA DR , WEYMANN JURGEN DR , ZIERKE THOMAS DR
Abstract: Novel peptides of the formula R R N-CHX-CO-A-B-D-E-(G)s-K in which R , R , A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.
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公开(公告)号:CZ24398A3
公开(公告)日:1998-07-15
申请号:CZ24398
申请日:1996-07-12
Applicant: BASF AG
Inventor: AMBERG WILHELM DR , BERNARD HARALD DR , BUSCHMANN ERNST DR , HAUPT ANDREAS DR , JANSSEN BERND DR , KARL ULRICH DR , KLING ANDREAS DR , MULLER STEFAN DR , RITTER KURT DR , ZIERKE THOMAS DR
IPC: C07K1/02 , C07K1/12 , C07K5/06 , C07K5/078 , C07K5/08 , C07K5/083 , C07K5/10 , C07K5/103 , C07K7/06
Abstract: PCT No. PCT/EP96/03073 Sec. 371 Date Jan. 13, 1998 Sec. 102(e) Date Jan. 13, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05162 PCT Pub. Date Feb. 13, 1997A process for preparing pentapeptides of the formula I where A and R1-R3 have the stated meanings, comprises assembling the pentapeptide stepwise starting from a prolinamide of the formula II where R1 and R2 have the abovementioned meanings, and eliminating the group -NR1R2 by hydrolysis where appropriate the peptide obtained in this way.
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公开(公告)号:ES2099530T3
公开(公告)日:1997-05-16
申请号:ES94119479
申请日:1994-12-09
Applicant: BASF AG
Inventor: JANITSCHKE LOTHAR DR , BUSCHMANN ERNST DR
IPC: C07C231/02
Abstract: A process is described for the preparation of ultrapure isobutyramide which comprises reacting isobutyryl chloride with ammonia in toluene or xylene at -15 to 30 DEG C.
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公开(公告)号:CZ326096A3
公开(公告)日:1997-04-16
申请号:CZ326096
申请日:1995-04-26
Applicant: BASF AG
Inventor: AMBERG WILHELM DR , BERNARD HARALD DR , BUSCHMANN ERNST DR , HAUPT ANDREAS DR , JANITSCHKE LOTHAR DR , JANSSEN BERND DR , KARL ULRICH DR , KLING ANDREAS DR , MULLER STEFAN DR , DE POTZOLLI BERND DR , RITTER KURT DR , THYES MARCO DR , ZIERKE THOMAS DR
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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公开(公告)号:DE4343175A1
公开(公告)日:1995-06-22
申请号:DE4343175
申请日:1993-12-17
Applicant: BASF AG
Inventor: JANITSCHKE LOTHAR DR , BUSCHMANN ERNST DR
IPC: C07C231/02 , C07C233/02 , C07C231/24
Abstract: A process is described for the preparation of ultrapure isobutyramide which comprises reacting isobutyryl chloride with ammonia in toluene or xylene at -15 to 30 DEG C.
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公开(公告)号:DE59200819D1
公开(公告)日:1995-01-12
申请号:DE59200819
申请日:1992-02-21
Applicant: BASF AG
Inventor: MACKENROTH CHRISTIANE , BUSCHMANN ERNST DR
IPC: C07C67/313 , C07C45/42 , C07C45/52 , C07C45/59 , C07C45/60 , C07C47/21 , C07C47/225 , C07C47/232 , C07C47/263 , C07C47/277 , C07C69/007 , C07C69/145 , C07C403/14
Abstract: Method for the production of alpha , beta -unsaturated aldehydes and ketones I,… O=C(R )-CR =CR R I,… by acid hydrolysis of cyclic alpha , beta -unsaturated acetals II, … … in the presence of saturated aldehydes.
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公开(公告)号:ES2063431T3
公开(公告)日:1995-01-01
申请号:ES91122072
申请日:1991-12-21
Applicant: BASF AG
Inventor: NEUMANN ULRICH DR , BUEHRLE HANS , RENZ GUENTER DR , BUSCHMANN ERNST DR
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公开(公告)号:ES2061588T3
公开(公告)日:1994-12-16
申请号:ES88116480
申请日:1988-10-05
Applicant: BASF AG
IPC: C07C43/13 , C07C27/00 , C07C29/09 , C07C29/17 , C07C29/32 , C07C29/36 , C07C29/42 , C07C33/035 , C07C41/00 , C07C41/20 , C07C41/30 , C07C43/178 , C07C45/29 , C07C47/263 , C07C47/277 , C07C67/00 , C07C67/08 , C07C69/007 , C07F7/18
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公开(公告)号:AT114626T
公开(公告)日:1994-12-15
申请号:AT92102915
申请日:1992-02-21
Applicant: BASF AG
Inventor: MACKENROTH CHRISTIANE , BUSCHMANN ERNST DR
IPC: C07C67/313 , C07C45/42 , C07C45/52 , C07C45/59 , C07C45/60 , C07C47/21 , C07C47/225 , C07C47/232 , C07C47/263 , C07C47/277 , C07C69/007 , C07C69/145 , C07C403/14
Abstract: Method for the production of alpha , beta -unsaturated aldehydes and ketones I,… O=C(R )-CR =CR R I,… by acid hydrolysis of cyclic alpha , beta -unsaturated acetals II, … … in the presence of saturated aldehydes.
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公开(公告)号:DE59103361D1
公开(公告)日:1994-12-01
申请号:DE59103361
申请日:1991-12-21
Applicant: BASF AG
Inventor: NEUMANN ULRICH DR , BUEHRLE HANS , RENZ GUENTER DR , BUSCHMANN ERNST DR
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