公开(公告)号：JP2013209432A

公开(公告)日：2013-10-10

申请号：JP2013140738

申请日：2013-07-04

Applicant: Basf Se ,  ビーエーエスエフ ソシエタス・ヨーロピアBasf Se

Inventor： HEYDRICH GUNNAR ,  GRALLA GABRIELE ,  RAULS MATTHIAS DR ,  SCHMIDT-LEITHOFF JOACHIM ,  EBEL KLAUS DR ,  KRAUSE WOLFGANG DR ,  OEHLENSCHLAEGER STEFFEN ,  JAEKEL CHRISTOPH ,  FRIEDRICH MARKO ,  BERGNER EIKE JOHANNES ,  KASHANI-SHIRAZI NAWID ,  PACIELLO ROCCO

IPC: C07C29/156 ,  B01J31/28 ,  C07B53/00 ,  C07B61/00 ,  C07C35/12

CPC classification number: C07C29/56 ,  C07B2200/07 ,  C07C29/172 ,  C07C29/78 ,  C07C45/62 ,  C07C45/82 ,  C07C2601/14 ,  C07C2601/16 ,  C07C47/21 ,  C07C35/12 ,  C07C35/17

Abstract: PROBLEM TO BE SOLVED: To provide a method enabling to manufacture optically active menthol, desirably L-menthol and racemic menthol in a variety of quantity according to the demand without changing an enantioselective catalyst system and/or without excessively obtaining one of products for need of changing a reaction condition.SOLUTION: A method for producing menthol includes a process (a. 1) of obtaining a citronellal by catalyst-hydrogenation of a neral and/or a geranial, a process (b. 1) of obtaining an isopulegol by cyclizing citronellal in the presence of an acid catalyst, a process (c. 1) of purifying the isopulegol by crystallization, and a process (d. 1) of producing menthol by catalyst-hydrogenation of the isopulegol.

Abstract translation: 要解决的问题：提供一种能够根据需要以不需要改变对映体选择性催化剂体系，和/或不过度地获得需要的物质的产品之一来制备光学活性薄荷醇，理想的L-薄荷醇和外消旋薄荷醇， 改变反应条件。解决方案：制备薄荷醇的方法包括通过催化剂氢化和/或香草醛获得香茅醛的方法（a.1），通过环化获得异焦耳的方法（b.1） 在酸催化剂存在下的香茅醛，通过结晶纯化异焦耳的方法（c.1），以及通过异双胍的催化氢化制备薄荷醇的方法（d.1）。

公开(公告)号：WO2009068444A3

公开(公告)日：2010-05-27

申请号：PCT/EP2008065503

申请日：2008-11-13

Applicant: BASF SE ,  HEYDRICH GUNNAR ,  GRALLA GABRIELE ,  RAULS MATTHIAS ,  SCHMIDT-LEITHOFF JOACHIM ,  EBEL KLAUS ,  KRAUSE WOLFGANG ,  OEHLENSCHLAEGER STEFFEN ,  JAEKEL CHRISTOPH ,  FRIEDRICH MARKO ,  BERGNER EIKE JOHANNES ,  KASHANI-SHIRAZI NAWID ,  PACIELLO ROCCO

Inventor： HEYDRICH GUNNAR ,  GRALLA GABRIELE ,  RAULS MATTHIAS ,  SCHMIDT-LEITHOFF JOACHIM ,  EBEL KLAUS ,  KRAUSE WOLFGANG ,  OEHLENSCHLAEGER STEFFEN ,  JAEKEL CHRISTOPH ,  FRIEDRICH MARKO ,  BERGNER EIKE JOHANNES ,  KASHANI-SHIRAZI NAWID ,  PACIELLO ROCCO

IPC: C07C29/17

CPC classification number: C07C29/56 ,  C07B2200/07 ,  C07C29/172 ,  C07C29/78 ,  C07C45/62 ,  C07C45/82 ,  C07C2601/14 ,  C07C2601/16 ,  C07C47/21 ,  C07C35/12 ,  C07C35/17

Abstract: The invention relates to a particularly economic, complete method for producing menthol, especially for the production of optically active, essentially enantiomerically and diastereomerically pure L-menthol and of racemic menthol starting from the commercially accessible, inexpensive parent material citral. The method comprises the following steps: a.1 ) catalytic hydrogenation of neral and/or geranial to form citronellal, b.1 ) cyclisation of citronellal to form isopulegol in the presence of an acidic catalyst, c.1 ) purification of isopulegol by crystallisation and d.1 ) catalytic hydrogenation of isopulegol to form menthol.

Abstract translation: 本发明涉及一种用于制备薄荷醇高度经济整个过程，特别地用于制备光学活性的，基本上对映体和非对映异构纯的L-薄荷醇和外消旋薄荷醇从在工业规模的起始材料的柠檬醛可用廉价的速率开始。 该方法包括以下步骤A.1）橙花醛的催化氢化和/或香叶到香茅醛，B.1）香茅醛在酸催化剂的存在下异胡薄荷醇，C.1）通过结晶和D.1异胡薄荷醇的纯化的环化） 胡薄荷醇的催化加氢：薄荷。

公开(公告)号：WO2008046918A3

公开(公告)日：2008-07-31

申请号：PCT/EP2007061229

申请日：2007-10-19

Applicant: BASF SE ,  RUDOLPH JENS ,  PACIELLO ROCCO ,  JAEKEL CHRISTOPH ,  HETTCHE FRANK ,  BOERNER ARMIN ,  DUBROVINA NATALIA ,  BIRKHOLZ MANDY-NICOLE ,  BREIT BERNHARD

Inventor： RUDOLPH JENS ,  PACIELLO ROCCO ,  JAEKEL CHRISTOPH ,  HETTCHE FRANK ,  BOERNER ARMIN ,  DUBROVINA NATALIA ,  BIRKHOLZ MANDY-NICOLE ,  BREIT BERNHARD

IPC: C07B37/02 ,  B01J31/18 ,  C07C29/16 ,  C07C45/50 ,  C07D211/76

CPC classification number: C07C45/50 ,  B01J31/1845 ,  B01J31/2409 ,  B01J31/2438 ,  B01J31/2452 ,  B01J31/2466 ,  B01J31/2471 ,  B01J2231/32 ,  B01J2231/321 ,  B01J2231/323 ,  B01J2231/325 ,  B01J2231/326 ,  B01J2231/342 ,  B01J2231/44 ,  B01J2231/52 ,  B01J2231/543 ,  B01J2231/645 ,  B01J2531/0266 ,  B01J2531/0291 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/842 ,  B01J2531/847 ,  B01J2531/94 ,  C07B53/00 ,  C07B2200/07 ,  C07C45/505 ,  C07C45/72 ,  C07C67/303 ,  C07C231/12 ,  C07F9/65683 ,  C07F15/0073 ,  C07C69/34 ,  C07C233/47

Abstract: The present invention relates to a method for reacting compounds, comprising at least one carbon-carbon or carbon-heteroatom double bond, by 1,2-addition in the presence of a catalyst, comprising at least one transition metal complex having at least two ligands, which each have a pnicogen atom-containing group and at least one functional group enable to form intermolecular, non-covalent bonds, in the presence of a halogenated solvent, which has at least one heteroatom different from halogen. The present invention further relates to a method for producing chiral compounds in the presence of the above-described catalysts and solvents, and to the use of these catalysts in the presence of such solvents.

Abstract translation: 本发明涉及一种用于反应包含至少一个碳 - 碳或碳 - 杂原子双键，由1,2-加成在催化剂的存在下的化合物包含至少一种过渡金属配合物具有至少两个配位体各自具有pnicogenatomhaltige的处理 基团和至少一个能够形成分子间非共价键官能团的基团，并且在具有至少一个除卤素以外的杂原子的卤化溶剂存在下进行。 本发明进一步涉及在上述催化剂和溶剂存在下制备手性化合物的方法以及这些催化剂在这些溶剂存在下的用途。

公开(公告)号：WO2011012687A3

公开(公告)日：2011-03-31

申请号：PCT/EP2010061075

申请日：2010-07-30

Applicant: BASF SE ,  JAEKEL CHRISTOPH ,  HOFMANN PETER ,  SCRIBAN CORINA ,  HANNO-IGELS PATRICK

Inventor： JAEKEL CHRISTOPH ,  HOFMANN PETER ,  SCRIBAN CORINA ,  HANNO-IGELS PATRICK

IPC: C07F9/6506 ,  C07B37/02 ,  C07B53/00 ,  C07F15/00 ,  C07F15/04

CPC classification number: C07F9/65061 ,  C07F5/022 ,  C07F9/65062 ,  C07F15/006 ,  C07F15/0086 ,  C07F15/04

Abstract: The present invention relates to phosphine borane compounds comprising imidazol groups, optically active ligands produced using said compounds, transition metal complexes comprising such ligands, and catalyzers comprising said transition metal complexes. The present invention further relates to methods for producing each of the phosphine borane compounds, the optically active ligands, the transition metal complexes, and the catalyzers, as well as the use of the catalyzers for organic transformation reactions. The present invention further relates to a method for producing phosphor compounds comprising imidazol groups and comprising optically active ligands, using phosphine borane compounds comprising imidazol groups.

Abstract translation: 本发明涉及含有咪唑基的膦硼烷化合物，使用它们，制备的光学活性配体，含有这种配体的过渡金属配合物，以及包含这种过渡金属配合物的催化剂。 此外，本发明涉及用于制备膦硼烷化合物，光学活性配体，过渡金属络合物和催化剂的各种方法以及该催化剂用于有机转化反应的用途。 此外，本发明涉及使用含咪唑的膦硼烷化合物制备含咪唑的磷化合物的光学活性配体的方法。

公开(公告)号：WO2009153272A3

公开(公告)日：2010-03-11

申请号：PCT/EP2009057496

申请日：2009-06-17

Applicant: BASF SE ,  JAEKEL CHRISTOPH ,  SERRA DANIEL ,  VINOKUROV NIKOLAI ,  MELDER JOHANN-PETER

Inventor： JAEKEL CHRISTOPH ,  SERRA DANIEL ,  VINOKUROV NIKOLAI ,  MELDER JOHANN-PETER

IPC: C07F1/12 ,  C07B39/00 ,  C07C17/12 ,  C07D213/61

CPC classification number: C07F1/12 ,  B01J31/181 ,  B01J2531/18 ,  C07B39/00 ,  C07C17/12 ,  C07C209/74 ,  C07D213/06 ,  C07D213/61 ,  C07D401/04 ,  C07C211/52

Abstract: The invention relates to a method for iodinating aromatic and/or heteroaromatic compounds, characterized in that aromatic compounds are reacted with an iodine source in the presence of at least one base and at least one catalyst containing gold. The invention further relates to catalysts containing gold and a method for producing the same. The invention additionally relates to a method for producing aniline.

Abstract translation: 本发明涉及一种用于芳族和/或杂芳族化合物，其特征在于，芳族化合物与碘的至少一个基极和实现的含金的催化剂的存在下，源的碘化。 此外，本发明涉及含有金的催化剂和它们的制备方法。 此外，本发明涉及用于生产苯胺的方法。

公开(公告)号：CA2715225A1

公开(公告)日：2009-08-20

申请号：CA2715225

申请日：2009-02-13

Applicant: BASF SE

Inventor： HOFMANN PETER ,  HANNO-IGELS PATRICK ,  BONDAREV OLEG ,  JAEKEL CHRISTOPH

IPC: C07F9/6506 ,  C07B37/02 ,  C07B53/00 ,  C07F9/6568 ,  C07F9/6571

Abstract: The invention relates to imidazole group-containing phosphorus compounds according to general formula (I) or (II), wherein W is phosphorus (P) or phosphite (P=O), to optically active ligands produced while using the same, to transition metal complexes containing said ligands, and to catalysts comprising said transition metal complexes. The invention further relates to the respective methods for producing the phosphorus compounds, the optically active ligands, the transition metal complexes and the catalysts, and to the use of the catalysts for organic transformation reactions.

公开(公告)号：AT525381T

公开(公告)日：2011-10-15

申请号：AT08867422

申请日：2008-12-16

Applicant: BASF SE

Inventor： JAEKEL CHRISTOPH ,  STEINKE TOBIAS HEINZ ,  REIMER VALENTINE ,  GOVINDASWAMY PADAVATTAN ,  DIAZ-VALENZUELA MARIA-BELEN

IPC: C07F15/04 ,  C08F4/70 ,  C08F10/00

公开(公告)号：DE502006007443D1

公开(公告)日：2010-08-26

申请号：DE502006007443

申请日：2006-08-15

Applicant: BASF SE

Inventor： RAULS MATTHIAS ,  JAEKEL CHRISTOPH ,  KASHANI-SHIRAZI NAWID ,  EBEL KLAUS

IPC: C07C29/78 ,  B01D9/00 ,  C07C29/17 ,  C07C29/56 ,  C07C35/12 ,  C07C35/17 ,  C11B9/00

公开(公告)号：DE502004010307D1

公开(公告)日：2009-12-10

申请号：DE502004010307

申请日：2004-11-24

Applicant: BASF SE

Inventor： JAEKEL CHRISTOPH ,  VOLLAND MARTIN ,  MACKEWITZ THOMAS ,  PACIELLO ROCCO ,  BREIT BERNHARD ,  SEICHE WOLFGANG ,  WEIS MARTINE ,  WALOCH CHRISTOPH

IPC: C07F9/58 ,  C07B53/00 ,  C07F9/6571

Abstract: The present invention relates to a process for asymmetric synthesis in the presence of a chiral catalyst comprising at least one complex of a metal of transition group VIII with ligands capable of dimerization via noncovalent bonds, such catalysts and their use.

公开(公告)号：CA2768744A1

公开(公告)日：2011-02-03

申请号：CA2768744

申请日：2010-07-30

Applicant: BASF SE

Inventor： JAEKEL CHRISTOPH ,  HOFMANN PETER ,  SCRIBAN CORINA ,  HANNO-IGELS PATRICK

IPC: C07F9/6506 ,  C07B37/02 ,  C07B53/00 ,  C07F15/00 ,  C07F15/04

Abstract: The present invention relates to phosphine borane compounds comprising imidazol groups, optically active ligands produced using said compounds, transition metal complexes comprising such ligands, and catalyzers comprising said transition metal complexes. The present invention further relates to methods for producing each of the phosphine borane compounds, the optically active ligands, the transition metal complexes, and the catalyzers, as well as the use of the catalyzers for organic transformation reactions. The present invention further relates to a method for producing phosphor compounds comprising imidazol groups and comprising optically active ligands, using phosphine borane compounds comprising imidazol groups.