公开(公告)号：DE19704990A1

公开(公告)日：1997-08-21

申请号：DE19704990

申请日：1997-02-10

Applicant: KAO CORP

Inventor： HOSHINO MASAHIDE ,  SUGIYAMA MITSURU

IPC: A61K8/55 ,  A61K8/00 ,  A61K8/58 ,  A61K8/89 ,  A61Q1/00 ,  A61Q1/12 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q17/04 ,  A61Q19/00 ,  C07F7/08 ,  C08G77/38 ,  C08L83/04 ,  C09K3/00 ,  A61K7/06 ,  A61K7/42 ,  C07F7/18 ,  C08G77/04 ,  C08G77/14

Abstract: Benzalmalonate derivative-modified organo(poly)siloxanes of formula (I) are new. R = hydrocarbyl; p = 0-3; R = hydrocarbyl (optionally containing O bonded to C or between two C); A,B = organo(poly)siloxane residues, or together complete an organo(poly)siloxane residue.

公开(公告)号：DE60043187D1

公开(公告)日：2009-12-03

申请号：DE60043187

申请日：2000-03-08

Applicant: KAO CORP

Inventor： HOSHINO MASAHIDE ,  SUGAI YOSHIYA ,  KAMEYAMA AKIYO ,  SAITO HIROAKI ,  NISHIZAWA YOSHINORI ,  TAKAGI YUTAKA

IPC: A61Q19/00 ,  A61K8/42 ,  A61K31/131 ,  A61K31/16 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q17/00 ,  A61Q19/08 ,  C07C233/18 ,  C07C233/20

公开(公告)号：DE60229460D1

公开(公告)日：2008-12-04

申请号：DE60229460

申请日：2002-03-01

Applicant: KAO CORP

Inventor： HOSHINO MASAHIDE ,  SAITO HIROAKI ,  SUGAI YOSHIYA ,  SUGIYAMA MITSURU ,  NISHIZAWA YOSHINORI ,  KATAYAMA YASUSHI

IPC: A61K31/16 ,  A61Q19/00 ,  A61K8/42 ,  A61Q5/02 ,  A61Q17/00 ,  A61Q17/04

Abstract: The present invention relates to a composition for external application, containing a diamide derivative represented by the following formula (1) : (wherein R 1a and R 1b are the same or different and each represents a C 1-23 hydrocarbon group, R 2a and R 2b are the same or different and each represents a divalent C 1-6 hydrocarbon group, R 3 s are the same or different and each represents a divalent C 2-6 hydrocarbon group and n stands for 1 to 100). The composition for external application basically improves the water retaining ability and barrier functions of the horny layer, is excellent in miscibility and mixing stability and can be prepared efficiently at a low cost.

公开(公告)号：DE69611444T2

公开(公告)日：2001-06-07

申请号：DE69611444

申请日：1996-05-16

Applicant: KAO CORP

Inventor： MURAYAMA KOICHI ,  HOSHINO MASAHIDE ,  KUSUOKU HIROSHI ,  NAGAI MINORU ,  SUGINO KIYOKO

IPC: C07D303/18 ,  A61K8/00 ,  A61K8/30 ,  A61K8/41 ,  A61K8/42 ,  A61K8/68 ,  A61K31/16 ,  A61K31/195 ,  A61Q5/00 ,  A61Q19/00 ,  C07C217/28 ,  C07C231/02 ,  C07C231/12 ,  C07C233/05 ,  C07C233/18 ,  A61K7/48

公开(公告)号：DE69611444D1

公开(公告)日：2001-02-08

申请号：DE69611444

申请日：1996-05-16

Applicant: KAO CORP

Inventor： MURAYAMA KOICHI ,  HOSHINO MASAHIDE ,  KUSUOKU HIROSHI ,  NAGAI MINORU ,  SUGINO KIYOKO

IPC: C07D303/18 ,  A61K8/00 ,  A61K8/30 ,  A61K8/41 ,  A61K8/42 ,  A61K8/68 ,  A61K31/16 ,  A61K31/195 ,  A61Q5/00 ,  A61Q19/00 ,  C07C217/28 ,  C07C231/02 ,  C07C231/12 ,  C07C233/05 ,  C07C233/18 ,  A61K7/48

公开(公告)号：EP1166766A4

公开(公告)日：2006-01-11

申请号：EP00907931

申请日：2000-03-08

Applicant: KAO CORP

Inventor： HOSHINO MASAHIDE ,  SUGAI YOSHIYA ,  KAMEYAMA AKIYO ,  SAITO HIROAKI ,  NISHIZAWA YOSHINORI ,  TAKAGI YUTAKA

IPC: A61K8/42 ,  A61K31/131 ,  A61K31/16 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/08 ,  C07C233/18 ,  C07C233/20 ,  A61K7/48 ,  A61K7/00 ,  A61K7/06

CPC classification number: C07C233/20 ,  A61K8/42 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/08 ,  C07C233/18

Abstract: External preparation compositions containing diamide derivatives represented by the general formula (1): wherein R1 represents optionally hydroxylated and/or alkoxylated linear or branched C¿1-22? hydrocarbyl; R?2¿ represents linear or branched divalent C¿1-12? hydrocarbyl; and R?3¿ represents linear or branched divalent C¿1-42? hydrocarbyl. These diamide derivatives (1) essentially improve the water retention function and barrier function of the horny layer, are excellent in blending properties and blending stability and can be produced efficiently and economically.