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公开(公告)号：DE69732796T2
公开(公告)日：2006-05-04
申请号：DE69732796
申请日：1997-10-08
Applicant: KAO CORP
Inventor： FUJIMURA TSUTOMU , ITO NORIKO , NAGAI MINORU , ONO TOSHIYA , YAMAMURO AKIRA , TAKEMA YOSHINORI
IPC: A01N43/00 , A01N43/36 , A01N43/40 , A01N43/58 , A01N43/64 , A61K6/00 , A61K8/49 , A61K31/395 , A61K31/397 , A61K31/40 , A61K31/41 , A61K31/435 , A61K31/445 , A61K31/495 , A61K31/50 , A61K31/535 , A61P17/00 , A61Q19/08
Abstract: Wrinkling modifiers and anti-aging cosmetic preparations which contain guanidine derivatives of general formula (1) or salts thereof, wherein (a) is a group derived from a heterocyclic compound selected from among azetidine, pyrrolidine, piperidine, piperazine and morpholine; and R and R are each independently hydrogen, alkyl, hydroxyl, hydroxyalkyl, carboxyl, carboxyalkyl or amidino. The cosmetic preparations are excellent in the effect of suppressing wrinkling and the effect of making wrinkles disappear and exhibit an excellent feeling in use
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公开(公告)号：DE69209513D1
公开(公告)日：1996-05-02
申请号：DE69209513
申请日：1992-09-22
Applicant: KAO CORP
Inventor： OHASHI YUKIHIRO , FUJIMORI TAKETOSHI , NAGAI MINORU , KAWAMATA AKIRA , YADA YUKIHIRO , HIGUCHI KAZUHIKO , IMOKAWA GENJI , TAKEMA YOSHINORI , SAKAINO YUKIKO , OGAWA AYUMI , FUJIMURA TSUTOMU
Abstract: PCT No. PCT/JP92/01210 Sec. 371 Date Mar. 23, 1994 Sec. 102(e) Date Mar. 23, 1994 PCT Filed Sep. 22, 1992 PCT Pub. No. WO93/05763 PCT Pub. Date Apr. 1, 1993A composition for external skin care comprising an amine derivative represented by the following formula (1), (1) wherein R1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R2, R3, R4, R5 and R6 are individually a hydrogen atom or a hydrocarbon group having 1-10 carbon atoms, which may be substituted or unsubstituted by 1 or more hydroxy groups; or an acid addition salt thereof, in an amount from 0.0001 to less than 0.1% by weight; and a method of curing wrinkles and keratinization of the skin characterized by applying said amine derivative or its salt to the skin.
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公开(公告)号：EP0965327A4
公开(公告)日：2001-08-29
申请号：EP97943153
申请日：1997-10-08
Applicant: KAO CORP
Inventor： FUJIMURA TSUTOMU , ITO NORIKO , NAGAI MINORU , ONO TOSHIYA , YAMAMURO AKIRA , TAKEMA YOSHINORI
IPC: A01N43/00 , A01N43/36 , A01N43/40 , A01N43/58 , A01N43/64 , A61K6/00 , A61K8/49 , A61K31/395 , A61K31/397 , A61K31/40 , A61K31/41 , A61K31/435 , A61K31/445 , A61K31/495 , A61K31/50 , A61K31/535 , A61P17/00 , A61Q19/08 , A61K7/48 , A61K7/00
CPC classification number: A61Q19/08 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/494
Abstract: Wrinkling modifiers and anti-aging cosmetic preparations which contain guanidine derivatives of general formula (1) or salts thereof, wherein (a) is a group derived from a heterocyclic compound selected from among azetidine, pyrrolidine, piperidine, piperazine and morpholine; and R and R are each independently hydrogen, alkyl, hydroxyl, hydroxyalkyl, carboxyl, carboxyalkyl or amidino. The cosmetic preparations are excellent in the effect of suppressing wrinkling and the effect of making wrinkles disappear and exhibit an excellent feeling in use.
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公开(公告)号：DE19527313B4
公开(公告)日：2012-01-26
申请号：DE19527313
申请日：1995-07-26
Applicant: KAO CORP
Inventor： NAGAI MINORU , KAWADA HIROMITSU , TSUCHIYA MAYUMI , YAMASAKI SEIJI , YAMAMURO AKIRA , ONO TOSHIYA
IPC: A61K8/43 , A61K8/02 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/46 , A61K8/49 , A61K8/73 , A61Q19/00 , C07C279/08 , C07D207/16 , C07F9/09
Abstract: Verwendung eines Guanidinderivates, das durch die Formeln (1), (2) oder (3) dargestellt ist, oder eines Säureadditionssalz davon als Hautkosmetikum zum Weichmachen der Keratinschichtworin in Formel (1): A und B gleich oder voneinander verschieden sein können und jeweils eine Alkylengruppe mit 2 bis 8 Kohlenstoffatomen darstellen; D eine Einfachbindung, -CO- oder eine Alkylengruppe, die 1 bis 6 Kohlenstoffatome hat und die eine Substituentengruppe haben kann, darstellt; E ein Wasserstoffatom, eine Niedrigalkylgruppe, eine Aralkylgruppe oder eine Arylgruppe, die eine Substituentengruppe haben kann, darstellt; m eine ganze Zahl von 1 bis 6 ist; n eine ganze Zahl von 1 bis 6 ist; und R1 ein Wasserstoffatom, eine Niedrigalkylgruppe oder -(AO)m-(BO)n-D-E darstellt, unter der Voraussetzung, dass -(AO)m-(BO)n-D-E keine Hydroxyethylgruppe ist, wenn R1 eine Methylgruppe ist; in Formel (2): l eine ppe, Carboxylgruppe oder eine Phosphorsäuregruppe ist; und R1 wie oben definiert ist;...
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公开(公告)号：DE69732796D1
公开(公告)日：2005-04-21
申请号：DE69732796
申请日：1997-10-08
Applicant: KAO CORP
Inventor： FUJIMURA TSUTOMU , ITO NORIKO , NAGAI MINORU , ONO TOSHIYA , YAMAMURO AKIRA , TAKEMA YOSHINORI
IPC: A01N43/00 , A01N43/36 , A01N43/40 , A01N43/58 , A01N43/64 , A61K6/00 , A61K8/49 , A61K31/395 , A61K31/397 , A61K31/40 , A61K31/41 , A61K31/435 , A61K31/445 , A61K31/495 , A61K31/50 , A61K31/535 , A61P17/00 , A61Q19/08 , A61K7/48 , A61K7/00
Abstract: Wrinkling modifiers and anti-aging cosmetic preparations which contain guanidine derivatives of general formula (1) or salts thereof, wherein (a) is a group derived from a heterocyclic compound selected from among azetidine, pyrrolidine, piperidine, piperazine and morpholine; and R and R are each independently hydrogen, alkyl, hydroxyl, hydroxyalkyl, carboxyl, carboxyalkyl or amidino. The cosmetic preparations are excellent in the effect of suppressing wrinkling and the effect of making wrinkles disappear and exhibit an excellent feeling in use
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Patent Agency Ranking
公开(公告)号：DE602005012006D1
公开(公告)日：2009-02-12
申请号：DE602005012006
申请日：2005-03-24
Applicant: KAO CORP
Inventor： NOJIRI MASAYOSHI , NAGAI MINORU
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公开(公告)号：DE69611444T2
公开(公告)日：2001-06-07
申请号：DE69611444
申请日：1996-05-16
Applicant: KAO CORP
Inventor： MURAYAMA KOICHI , HOSHINO MASAHIDE , KUSUOKU HIROSHI , NAGAI MINORU , SUGINO KIYOKO
IPC: C07D303/18 , A61K8/00 , A61K8/30 , A61K8/41 , A61K8/42 , A61K8/68 , A61K31/16 , A61K31/195 , A61Q5/00 , A61Q19/00 , C07C217/28 , C07C231/02 , C07C231/12 , C07C233/05 , C07C233/18 , A61K7/48
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公开(公告)号：DE69611444D1
公开(公告)日：2001-02-08
申请号：DE69611444
申请日：1996-05-16
Applicant: KAO CORP
Inventor： MURAYAMA KOICHI , HOSHINO MASAHIDE , KUSUOKU HIROSHI , NAGAI MINORU , SUGINO KIYOKO
IPC: C07D303/18 , A61K8/00 , A61K8/30 , A61K8/41 , A61K8/42 , A61K8/68 , A61K31/16 , A61K31/195 , A61Q5/00 , A61Q19/00 , C07C217/28 , C07C231/02 , C07C231/12 , C07C233/05 , C07C233/18 , A61K7/48
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公开(公告)号：DE69209513T2
公开(公告)日：1996-09-12
申请号：DE69209513
申请日：1992-09-22
Applicant: KAO CORP
Inventor： OHASHI YUKIHIRO , FUJIMORI TAKETOSHI , NAGAI MINORU , KAWAMATA AKIRA , YADA YUKIHIRO , HIGUCHI KAZUHIKO , IMOKAWA GENJI , TAKEMA YOSHINORI , SAKAINO YUKIKO , OGAWA AYUMI , FUJIMURA TSUTOMU
Abstract: PCT No. PCT/JP92/01210 Sec. 371 Date Mar. 23, 1994 Sec. 102(e) Date Mar. 23, 1994 PCT Filed Sep. 22, 1992 PCT Pub. No. WO93/05763 PCT Pub. Date Apr. 1, 1993A composition for external skin care comprising an amine derivative represented by the following formula (1), (1) wherein R1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R2, R3, R4, R5 and R6 are individually a hydrogen atom or a hydrocarbon group having 1-10 carbon atoms, which may be substituted or unsubstituted by 1 or more hydroxy groups; or an acid addition salt thereof, in an amount from 0.0001 to less than 0.1% by weight; and a method of curing wrinkles and keratinization of the skin characterized by applying said amine derivative or its salt to the skin.
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