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公开(公告)号：WO2013049702A9
公开(公告)日：2013-04-04
申请号：PCT/US2012/058096
申请日：2012-09-28
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： FREUDENTHAL, Jacob K. , DAHLHOFF, Geoffrey , MAHER, Kevin , CHEN, Mingsong , LIM, Gary , DANEHY, Ronald , FORTESCUE, David , SHEN, Ming , SOH, Woon Liang Terence , CHENG, Francis , WU, Ruoyun , LEE, Thiam Chye , CHAPPELL, Gary , LIM, Chee Kiong , DERE, Jeff , STRAUB, Ted , FONSECA, Jorge , BOO, Kuan Moon , LAU, Soo Yong
Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.
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Patent Agency Ranking
公开(公告)号：WO2018049251A1
公开(公告)日：2018-03-15
申请号：PCT/US2017/050806
申请日：2017-09-08
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： HABERSTROH, Marc , DAHLHOFF, Geoffrey
IPC: G01N27/447
Abstract: The present disclosure relates, in some embodiments, to a system for measuring capillary electrophoresis current. The system includes a plurality of capillaries (206), where each capillary has a cathode end and an anode end. The system further includes a plurality of cathode buffers (202). Each of the cathode buffers is configured to be electrically isolated from the other cathode buffers. Further, each cathode buffer (202) is associated with one capillary (206) of the plurality of capillaries. The cathode end of each capillary (206) is immersed in its associated cathode buffer (202). The system includes a plurality of current sensors (204), each current sensor associated with one capillary of the plurality of capillaries for measuring current. In some embodiments, the plurality of capillaries is four capillaries.
Abstract translation: 在一些实施例中，本公开涉及用于测量毛细管电泳电流的系统。 该系统包括多个毛细管（206），其中每个毛细管具有阴极端和阳极端。 该系统还包括多个阴极缓冲器（202）。 每个阴极缓冲器被配置为与其他阴极缓冲器电隔离。 此外，每个阴极缓冲器（202）与多个毛细管中的一个毛细管（206）相关联。 每个毛细管（206）的阴极端被浸入其相关的阴极缓冲器（202）中。 该系统包括多个电流传感器（204），每个电流传感器与多个毛细管中的一个毛细管相关联，用于测量电流。 在一些实施例中，多个毛细管是四个毛细管。
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3.发明申请THERMAL BLOCK ASSEMBLIES AND INSTRUMENTS PROVIDING LOW THERMAL NON-UNIFORMITY FOR RAPID THERMAL CYCLING 审中-公开为快速热循环提供低热量非均匀性的热块组件和仪器
公开(公告)号：WO2011028834A2
公开(公告)日：2011-03-10
申请号：PCT/US2010/047573
申请日：2010-09-01
Applicant: LIFE TECHNOLOGIES CORPORATION , WOJTOWICZ, Janusz , DAHLHOFF, Geoffrey , GRUNEWALD, Douglas W. , CONNER, Thomas A.
Inventor： WOJTOWICZ, Janusz , DAHLHOFF, Geoffrey , GRUNEWALD, Douglas W. , CONNER, Thomas A.
CPC classification number: H01L21/4882 , F28D2021/0029 , H01L23/467 , H01L2924/0002 , H01L2924/00
Abstract: The present teachings disclose various embodiments of a thermal block assembly having low thermal non-uniformity throughout the thermal block assembly. Accordingly, various embodiments of thermal block assemblies having such low thermal non-uniformity provide for desired performance of bioanalysis instrumentation utilizing such thermal block assemblies.
Abstract translation: 本教导公开了在整个热块组件中具有低热不均匀性的热块组件的各种实施例。 因此，具有这种低热不均匀性的热块组件的各种实施例提供利用这种热块组件的生物分析仪器的期望性能。
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公开(公告)号：EP3510391A1
公开(公告)日：2019-07-17
申请号：EP17768946.0
申请日：2017-09-08
Applicant: Life Technologies Corporation
Inventor： HABERSTROH, Marc , DAHLHOFF, Geoffrey
IPC: G01N27/447
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5.发明公开THERMAL BLOCK ASSEMBLIES AND INSTRUMENTS PROVIDING LOW THERMAL NON-UNIFORMITY FOR RAPID THERMAL CYCLING 审中-公开热火锁定安排与仪器低热不等式快速热循环
公开(公告)号：EP2473893A2
公开(公告)日：2012-07-11
申请号：EP10814448.6
申请日：2010-09-01
Applicant: Life Technologies Corporation
Inventor： WOJTOWICZ, Janusz , DAHLHOFF, Geoffrey , GRUNEWALD, Douglas W. , CONNER, Thomas A.
CPC classification number: H01L21/4882 , F28D2021/0029 , H01L23/467 , H01L2924/0002 , H01L2924/00
Abstract: The present teachings disclose various embodiments of a thermal block assembly having low thermal non-uniformity throughout the thermal block assembly. Accordingly, various embodiments of thermal block assemblies having such low thermal non-uniformity provide for desired performance of bioanalysis instrumentation utilizing such thermal block assemblies.
Abstract translation: 本发明的教导公开了具有低的热非均匀性在整个热块组件的热块组件的各种实施例。 因此，在审查的热块组件各种实施例中较低的热非均匀性提供了生物分析仪器利用寻求热块组件的期望的性能。
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6.发明公开
公开(公告)号：EP2760585A2
公开(公告)日：2014-08-06
申请号：EP12784373.8
申请日：2012-09-28
Applicant: Life Technologies Corporation
Inventor： FREUDENTHAL, Jacob K. , DAHLHOFF, Geoffrey , MAHER, Kevin , CHEN, Mingsong , LIM, Gary , DANEHY, Ronald , FORTESCUE, David , SHEN, Ming , SOH, Woon Liang Terence , CHENG, Francis , WU, Ruoyun , LEE, Thiam Chye , CHAPPELL, Gary , LIM, Chee Kiong , DERE, Jeff , STRAUB, Ted , FONSECA, Jorge , BOO, Kuan Moon , LAU, Soo Yong
CPC classification number: C12Q1/686 , B01L3/50855 , B01L3/50857 , B01L7/52 , B01L2200/023 , B01L2200/025 , B01L2200/028 , B01L2200/143 , B01L2300/021 , B01L2300/046 , B01L2300/0654 , B01L2300/0829 , B01L2300/1827 , B01L2300/1844
Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.
Abstract translation: 提供生物分析系统。 该系统包括被配置为容纳多个样本保持器中的任何一个的可互换组件，每个样本保持器被配置为接收多个样本。 该系统还包括配置成使多个样品循环通过一系列温度的控制系统。 该系统还包括被配置为检测从多个样本发射的荧光信号的光学系统。 特别地，光学系统可以包括单个场透镜，激发源，光学传感器和多个滤光器组件。 激发源可以是一个或多个发光二极管。 场透镜可以是双凸透镜。
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