中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

12 records (took 0.026 seconds)

    SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS
    1.
    发明申请
    SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS 审中-公开
    生物分析系统与方法

    公开(公告)号：WO2013049659A2

    公开(公告)日：2013-04-04

    申请号：PCT/US2012/058042

    申请日：2012-09-28

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： DANEHY, Ronald ,  LIM, Gary ,  FREUDENTHAL, Jacob

    IPC: B01L3/00 ,  C12M1/00

    CPC classification number: C12Q1/6806 ,  B01L3/50851 ,  B01L3/50855 ,  B01L3/50857 ,  B01L2200/026 ,  B01L2200/0642 ,  B01L2200/0684 ,  B01L2200/142 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/0858 ,  B01L2300/0893 ,  B01L2300/161 ,  C12M23/12 ,  C12M23/38

    Abstract: A case for containing a plurality of biological samples contains a base, a substrate and a cover. The substrate is attached to the base and comprises a plurality of reaction regions configured to receive one or more biological samples. The cover comprises an inner surface and is configured to be attached to the base such that the base and cover together provide a cavity containing the substrate. The inner surface includes a central area and a recessed area disposed about the central area. The central area is configured to cover the reaction regions, while the recessed area is offset from the central area in a direction normal to the inner surface.

    Abstract translation: 用于容纳多个生物样品的壳体包含基底，基底和盖。 底物附着到基底上，并且包括被配置成接收一个或多个生物样品的多个反应区域。 盖子包括内表面，并且被构造成附接到基座，使得基座和盖子一起提供容纳基底的空腔。 内表面包括中心区域和围绕中心区域设置的凹陷区域。 中心区域构造成覆盖反应区域，而凹陷区域在垂直于内表面的方向上偏离中心区域。

    CAPILLARY ELECTROPHORESIS SYSTEMS, RELATED DEVICES, AND RELATED METHODS
    4.
    发明申请
    CAPILLARY ELECTROPHORESIS SYSTEMS, RELATED DEVICES, AND RELATED METHODS 审中-公开

    公开(公告)号：WO2018156880A1

    公开(公告)日：2018-08-30

    申请号：PCT/US2018/019399

    申请日：2018-02-23

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： LIM, Gary ,  LIU, David ,  LI, Peng ,  CAO, Bin ,  HIRANO, Kirk ,  DUKHOVNY, Alexander ,  DIXON, John

    IPC: G01N27/447

    Abstract: A biological analysis device (100) for performing capillary electrophoresis includes a voltage section (124) configured to generate a voltage differential across a cathode (106) connector and an anode (116) connector, an optical detector system (112) configured to detect light emission from a sample, a temperature regulation section (126), and a cartridge holding portion configured to receive at least a portion of a removable cartridge (102) comprising one or more capillaries (104) and a separation medium container (118). The biological analysis device may include one or more actuators (122) configured to actuate components of the removable cartridge when the removable cartridge is received in the cartridge holding portion. Devices and methods relate to biological analysis.

    SYSTEMS AND METHODS FOR LOADING LIQUID SAMPLES
    5.
    发明申请
    SYSTEMS AND METHODS FOR LOADING LIQUID SAMPLES 审中-公开
    用于装载液体样品的系统和方法

    公开(公告)号：WO2015074076A1

    公开(公告)日：2015-05-21

    申请号：PCT/US2014/066225

    申请日：2014-11-18

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： LIM, Gary ,  STRAUB, Theodore

    IPC: B01L3/02

    CPC classification number: B01L3/0293 ,  B01L3/50857 ,  B01L2200/026 ,  B01L2200/0642 ,  B01L2300/0829 ,  B01L2300/0893 ,  B01L2300/12 ,  B01L2400/0406 ,  C12Q1/686

    Abstract: A sample loader for loading a liquid sample into a plurality of reaction sites within a substrate is provided. The sample loader includes a first blade, and a second blade coupled to the first blade. The sample loader further comprises a flow path between the first blade and second blade configured to dispense a liquid sample to a substrate including a plurality of reaction sites. Further, in various embodiments the liquid sample has an advancing contact angle of 85 +/- 15 degrees with the first and second blade. Furthermore, loading of the liquid sample dispensed from the flow path to the plurality of reaction sites may be based on capillary action. The first and second blade may dispense the liquid by laterally moving over the plurality of reaction sites, where a motor laterally moves the first and second blade.

    Abstract translation: 提供了一种用于将液体样品加载到基底内的多个反应位点的样品装载器。 样品装载器包括第一叶片和联接到第一叶片的第二叶片。 样品装载器还包括在第一叶片和第二叶片之间的流动路径，其构造成将液体样品分配到包括多个反应位点的基底。 此外，在各种实施例中，液体样品与第一和第二叶片具有85 +/- 15度的前进接触角。 此外，从流动路径分配到多个反应位点的液体样品的装载可以基于毛细作用。 第一和第二叶片可以通过横向移动多个反应部位来分配液体，其中马达横向移动第一和第二叶片。

    SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS
    6.
    发明申请
    SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS 审中-公开
    生物分析系统与方法

    公开(公告)号：WO2013138767A1

    公开(公告)日：2013-09-19

    申请号：PCT/US2013/032420

    申请日：2013-03-15

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： PALLAS, Michael, C. ,  NURSE, James ,  LIM, Gary ,  STRAUB, Theodore ,  GHENCIU, Eliodor ,  FOSTER, Evan ,  FONSECA, Jorge ,  MAHER, Kevin

    IPC: B01L7/00 ,  C12Q1/68 ,  B01L3/00

    CPC classification number: B01L3/50857 ,  B01L3/50 ,  B01L3/50851 ,  B01L2200/141 ,  B01L2300/0893 ,  B01L2300/0896 ,  B01L2300/161 ,  C12Q1/6806 ,  C12Q1/686 ,  G03F7/2002

    Abstract: A system for performing biological reactions is provided. The system includes a chip including a substrate and a plurality of reaction sites. The plurality of reaction sites are each configured to include a liquid sample of at most one nanoliter. Further, the system includes a control system configured to initiate biological reactions within the liquid samples. The system further includes a detection system configured to detect biological reactions on the chip. According to various embodiments, the chip includes at least 20000 reaction sites. In other embodiments, the chip includes at least 30000 reaction sites.

    Abstract translation: 提供了用于进行生物反应的系统。 该系统包括包括基底和多个反应位点的芯片。 多个反应位点各自被配置为包括至多一个纳升级的液体样品。 此外，该系统包括被配置为启动液体样品内的生物反应的控制系统。 该系统还包括被配置为检测芯片上的生物反应的检测系统。 根据各种实施方案，该芯片包括至少20000个反应位点。 在其它实施方案中，芯片包括至少30000个反应位点。

    SYSTEMS AND METHODS FOR LOADING LIQUID SAMPLES
    7.
    发明公开
    SYSTEMS AND METHODS FOR LOADING LIQUID SAMPLES 审中-公开
    系统和方法用于装载液体样品

    公开(公告)号：EP3071331A1

    公开(公告)日：2016-09-28

    申请号：EP14821331.7

    申请日：2014-11-18

    Applicant: Life Technologies Corporation

    Inventor： LIM, Gary ,  STRAUB, Theodore

    IPC: B01L3/02

    CPC classification number: B01L3/0293 ,  B01L3/50857 ,  B01L2200/026 ,  B01L2200/0642 ,  B01L2300/0829 ,  B01L2300/0893 ,  B01L2300/12 ,  B01L2400/0406 ,  C12Q1/686

    Abstract: A sample loader for loading a liquid sample into a plurality of reaction sites within a substrate is provided. The sample loader includes a first blade, and a second blade coupled to the first blade. The sample loader further comprises a flow path between the first blade and second blade configured to dispense a liquid sample to a substrate including a plurality of reaction sites. Further, in various embodiments the liquid sample has an advancing contact angle of 85 +/- 15 degrees with the first and second blade. Furthermore, loading of the liquid sample dispensed from the flow path to the plurality of reaction sites may be based on capillary action. The first and second blade may dispense the liquid by laterally moving over the plurality of reaction sites, where a motor laterally moves the first and second blade.

    SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS
    9.
    发明公开
    SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS 审中-公开
    系统和生物分析方法

    公开(公告)号：EP2760583A2

    公开(公告)日：2014-08-06

    申请号：EP12787175.4

    申请日：2012-09-28

    Applicant: Life Technologies Corporation

    Inventor： DANEHY, Ronald ,  LIM, Gary ,  FREUDENTHAL, Jacob

    IPC: B01L3/00 ,  C12M1/00

    Abstract: A case for containing a plurality of biological samples contains a base, a substrate and a cover. The substrate is attached to the base and comprises a plurality of reaction regions configured to receive one or more biological samples. The cover comprises an inner surface and is configured to be attached to the base such that the base and cover together provide a cavity containing the substrate. The inner surface includes a central area and a recessed area disposed about the central area. The central area is configured to cover the reaction regions, while the recessed area is offset from the central area in a direction normal to the inner surface.

Patent Agency Ranking