公开(公告)号：AU2020277027A1

公开(公告)日：2021-12-09

申请号：AU2020277027

申请日：2020-05-12

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  ALAM MD RAUFUL ,  AMEDZO LUKIANA ,  ARNOLD MICHAEL A ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  KARP GARY MITCHELL ,  KENTON NATHANIEL T ,  LUONG TOM TUAN ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  MORRILL CHRISTIE ,  MSZAR NICHOLAS WALTER ,  NARASIMHAN JANA ,  PATEL JIGAR S ,  REN HONGYU ,  TURPOFF ANTHONY ,  WANG GANG ,  WOLL MATTHEW G ,  ZHANG NANJING ,  ZHANG XIAOYAN

IPC: C07D401/14 ,  A61K31/501 ,  A61K31/53 ,  A61P25/28 ,  C07D413/14 ,  C07D417/14 ,  C07D487/04

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：CA3139821A1

公开(公告)日：2020-11-19

申请号：CA3139821

申请日：2020-05-12

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  ALAM MD RAUFUL ,  AMEDZO LUKIANA ,  ARNOLD MICHAEL A ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  KARP GARY MITCHELL ,  KENTON NATHANIEL T ,  LUONG TOM TUAN ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  MORRILL CHRISTIE ,  MSZAR NICHOLAS WALTER ,  NARASIMHAN JANA ,  PATEL JIGAR S ,  REN HONGYU ,  TURPOFF ANTHONY ,  WANG GANG ,  WOLL MATTHEW G ,  ZHANG NANJING ,  ZHANG XIAOYAN

IPC: C07D401/14 ,  A61K31/501 ,  A61K31/53 ,  A61P25/28 ,  C07D413/14 ,  C07D417/14 ,  C07D487/04

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：AU2021254418A1

公开(公告)日：2022-11-03

申请号：AU2021254418

申请日：2021-04-08

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  ALAM RAUFUL ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  CHEN GUANGMING ,  CHIERCHIA MATTEO ,  KARP GARY MITCHELL ,  LUONG TOM TUAN ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  MSZAR NICHOLAS WALTER ,  NARASIMHAN JANA ,  PATEL JIGAR S ,  REN HONGYU ,  WANG GANG ,  WOLL MATTHEW G ,  ZHANG NANJING ,  ZHANG XIAOYAN

IPC: C07D401/14 ,  A61K31/53 ,  A61P25/28 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D491/04 ,  C07D498/04 ,  C07D513/04

Abstract: The present description relates to compounds of Formula (I), forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：SG11202112504YA

公开(公告)日：2021-12-30

申请号：SG11202112504Y

申请日：2020-05-12

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  ALAM MD RAUFUL ,  AMEDZO LUKIANA ,  ARNOLD MICHAEL A ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  KARP GARY MITCHELL ,  KENTON NATHANIEL T ,  LUONG TOM TUAN ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  MORRILL CHRISTIE ,  NARASIMHAN JANA ,  MSZAR NICHOLAS WALTER ,  PATEL JIGAR S ,  REN HONGYU ,  TURPOFF ANTHONY ,  WANG GANG ,  WOLL MATTHEW G ,  ZHANG NANJING ,  ZHANG XIAOYAN

IPC: C07D401/14 ,  A61K31/501 ,  A61K31/53 ,  A61P25/28 ,  C07D413/14 ,  C07D417/14 ,  C07D487/04

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.